Elevated levels of homocysteine in the blood, known as hyperhomocysteinemia, have been linked to an increased risk of cardiovascular disease, including heart attack and stroke. High homocysteine levels may also be associated with an increased risk of certain other health conditions, such as osteoporosis and pregnancy complications.

Quest Diagnostics test code 17911 is for a DNA mutation analysis of Methylenetetrahydrofolate Reductase (MTHFR). The test determines if a patient has one, two, or no copies of either of the two mutations in the MTHFR gene, C677T and A1298C.

Changes in the methylenetetrahydrofolate reductase gene can lead to certain health conditions. One of them is hyperhomocysteinemia (high blood levels of homocysteine), which is a risk factor for cerebrovascular disease, cerebral vein thrombosis, coronary artery disease, myocardial infarction, and venous thrombosis. At least 40 mutations in the MTHFR gene have been identified in people with homocystinuria, a disorder in which the body is unable to process certain amino acids properly.

The Cardio IQ® Report provides an in-depth assessment of cardiovascular risks to help physicians recommend the ideal individualized treatment option for patient to minimize cardiovascular disease.

The report is simple, yet comprehensive. It is color-coded to display progressive risk values versus goal using “optimal,” “moderate,” and “high-risk” categories and grouped by functional categories.

Cardio IQ Advanced Lipid Panel The Cardio IQ Advanced Lipid Panel includes:Total Cholesterol, Triglycerides, HDL, LDL and Cholesterol/HDL ratio, LDL Particle Number, LDL Peak Size, LDL Pattern, HDL Large, LDL Small, LDL Medium, Apolipoprotein B, Lipoprotein (a). Fasting is not required prior to collection of a lipid panel. Results for this test take 2 weeks to receive.