Lipoprotein a

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Lipoprotein a
Special Price $42.00 Regular Price $55.25

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Lipoprotein(a) has been called a powerful predictor of premature atherosclerotic vascular disease. As an independent risk factor for premature coronary artery disease, excess Lp(a) concentrations are associated with an increased risk of cardiac death in patients with acute coronary syndromes and with restenosis after angioplasty (PTCA) and coronary bypass procedures. In general, concentrations greater than or equal to 75 nmol/L of Lp(a) in serum are associated with a two- to sixfold increase in risk, depending on the presence of other risk factors.

Lipoprotein(a)  has been called a powerful predictor of premature atherosclerotic vascular disease. As an independent risk factor for premature coronary artery disease, excess Lp(a) concentrations are associated with an increased risk of cardiac death in patients with acute coronary syndromes and with restenosis after angioplasty (PTCA) and coronary bypass procedures. In general, concentrations greater than or equal to 75 nmol/L of Lp(a) in serum are associated with a two- to sixfold increase in risk, depending on the presence of other risk factors.

Reference Range(s)

<75 nmol/L

Risk nmol/L
Optimal <75
Moderate 75-125
High >125


Cardiovascular event risk category cut points (optimal, moderate, high) are based on Tsimikas S. JACC 2017;69:692-711.

 

Lp(a) test is an independent risk factor for coronary artery disease and cerebral infarction (in white populations) equal to high LDL cholesterol. Serum concentrations are genetically determined. Fifteen percent to 20% of the white population have Lp(a) levels ≥75 nmol/L and are presumed to be at risk. Race-dependent differences in Lp(a) concentrations are known. The significance of high Lp(a) in nonwhite populations must be evaluated with caution. The Lp(a) levels in different ethnic populations can vary widely. Africans, or people of African descent, generally have Lp(a) levels higher than Caucasians and Asians, while Native Americans generally have levels lower than Caucasians. This variability of Lp(a) levels by ethnic population requires careful interpretation of results based on a knowledge of the patient and other cardiac risk factors that may be present.

A blood test called the Lipoprotein(a) [Lp(a)] test is used to determine the levels of Lipoprotein(a) [Lp(a)], a kind of lipoprotein that shares structural similarities with LDL (low-density lipoprotein), or "bad" cholesterol. Increased Lp(a) levels are regarded as a risk factor for cardiovascular disease because they can aid in the formation of arterial plaque.

The following are some Lp(a) test-related frequently asked questions:


What is the Lp(a) level normal range?
A: Lp(a) levels that are considered elevated are those that are greater than 30 mg/dL in the normal range. Some professionals define high readings as those more than 10 mg/dL.

What do elevated Lp(a) levels mean?
A: Heart attack, stroke, and peripheral artery disease are all related with an elevated risk of cardiovascular disease in people with high levels of Lp(a) (over 30 mg/dL).

What do low Lp(a) levels suggest?
A: A lower risk of cardiovascular disease is linked to low levels of Lp(a) (below 10 mg/dL).

What are the danger signs of elevated Lp(a) levels?
A: Family history of cardiovascular disease, advanced age, high LDL cholesterol levels, and a history of smoking are risk factors for high Lp(a) levels.

How can I reduce the amounts of Lp(a) in my body?
A: By changing your lifestyle to include regular exercise, a good diet, giving up smoking, and stress management, you can lower your Lp(a) levels. Medications like statins, for example, may also aid in lowering Lp(a) levels.

How exactly is the Lp(a) test run?
A blood sample is drawn for the Lp(a) test, which is subsequently sent to a lab for evaluation.

An Lp(a) test should be read in conjunction with other lipid panel tests, other clinical information, and laboratory data because it is not a diagnostic tool on its own. Additionally, it's crucial to speak with a medical professional to go through the findings and any possible health consequences.

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