The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells sediment in a period of one hour. It is a common hematology test and is a non-specific measure of inflammation. To perform the test, anticoagulated blood is traditionally placed in an upright tube, known as a Westergren tube, and the rate at which the red blood cells fall is measured and reported in mm at the end of one hour. Elevated levels of ESR are usually found in people who have different types of diseases, such as autoimmune disease, anemia, kidney disease, cancer, and other health complications.

Immunoglobulin A (IgA) is a crucial antibody in the immune system, predominantly found in mucous membranes of the respiratory and gastrointestinal tracts. It helps protect against infections by neutralizing pathogens before they can cause harm. Testing IgA levels can provide insights into immune health, indicating potential issues such as chronic infections, autoimmune diseases, or immunodeficiency disorders. Elevated or decreased IgA levels can signal various health conditions, making this test valuable for diagnosing and managing immune-related issues. For those experiencing frequent infections or gastrointestinal issues, an IgA test can be an essential diagnostic tool.

The Rheumatoid Arthritis Factor is often evaluated in patients suspected of having any form of arthritis or destructive articular disease even though positive results can be due to other causes, and negative results do not rule out disease. But, in combination with signs and symptoms, it can play a role in both diagnosis and disease prognosis. It is part of the usual disease criteria of rheumatoid arthritis.

The thyroid stimulating hormone (TSH) is produced and secreted by the pituitary gland and stimulates the thyroid to produce T3 and T4. When TSH is elevated, low thyroid function may be indicated. If TSH is low it is indicative of high thyroid function. A study found that TSH was suppressed in all subjects after food, so fasting may be suggested although it is not reqired by Quest. Free T4 and Free T4 values did not change significantly after eating.

A complete blood count CBC with differential test panel measures several components of your blood including:Red blood cells, which carry oxygen, White blood cells, which fight infection, Hemoglobin, the oxygen-carrying protein in red blood cells, Hematocrit, the proportion of red blood cells to the fluid component in your blood (which correlated with blood thickness), and Platelets, which help with blood clotting. This is also called Complete Blood Count (CBC) with Differential and Platelets Blood Test

Patients with diabetes may get a C-peptide test as a means of distinguishing type 1 diabetes from type 2 diabetes or Maturity onset diabetes of the young (MODY). Measuring C-peptide can help to determine how much of their own natural insulin a person is producing as C-peptide is secreted in equimolar amounts to insulin. C-peptide levels are measured instead of insulin levels because C-peptide can assess a person's own insulin secretion even if they receive insulin injections, and because the liver metabolizes a large and variable amount of insulin secreted into the portal vein but does not metabolize C-peptide, meaning blood C-peptide may be a better measure of portal insulin secretion than insulin itself.