Prothrombin with INR and Partial Thromboplastin Times (PTT)

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Prothrombin with INR and Partial Thromboplastin Times (PTT)
$38.00

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The tests are usually ordered for patients prior to surgery to ensure normal clotting ability.  The PT and PTT Blood Tests are useful in the diagnosis of excessive, unexplained bleeding in patients who are not taking blood-thinning medications. These bleeding disorders include conditions such as nosebleeds, bruising, heavy menstrual periods, blood in the stool and/or urine, and bleeding gums, among others,

This test is usually required before surgeries by doctors to ensure someone can coagulate properly during an operation.

Prothrombin with INR and Partial Thromboplastin Times - PT/INR: Screening test for abnormalities of coagulation factors that are involved in the extrinsic pathway. Also used to monitor effects of Warfarin therapy and to study patients with hereditary and acquired clotting disorders.

The PT and PTT Blood Tests are useful in the diagnosis of excessive, unexplained bleeding in patients who are not taking blood-thinning medications. These bleeding disorders include conditions such as nosebleeds, bruising, heavy menstrual periods, blood in the stool and/or urine, and bleeding gums, among others. The tests are also sometimes ordered for patients prior to surgery to ensure normal clotting ability.

A “prolonged” result means that a blood clot is taking longer than normal to form. There are a variety of causes for this, including coagulation/clotting factor deficiency/dysfunction, vitamin K deficiency, liver disease, inhibition by certain antibodies, and others. General interpretation of PT & PTT Blood Test results can be summarized as follows:

  • PT prolonged, PTT prolonged: Dysfunctional or insufficient coagulation factor I, II, V or X; acute disseminated intravascular coagulation (DIC) (abnormal activation of coagulation factors); severe liver disease

  • PT prolonged, PTT normal: Dysfunctional or insufficient coagulation factor VII, chronic low-grade DIC, insufficient vitamin K, liver disease, warfarin (anticoagulant) therapy

  • PT normal, PTT prolonged: Dysfunctional or insufficient coagulation factor VIII, IX or XI; severe von Willebrand disease (hereditary bleeding disorder); presence of lupus anticoagulant

  • PT normal, PTT normal or slightly prolonged: Normal clotting ability, mild deficiencies in other coagulation factors, mild form of von Willebrand disease

 

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