Epstein-Barr Virus (EBV) Antibodies Panel
Epstein-Barr (EB) virus is a herpes group virus that is ubiquitous. It is the cause of classic infectious mononucleosis and is causally implicated in the pathogenesis of Burkitt lymphoma, some nasopharyngeal carcinomas, and rare hereditary lymphoproliferative disorders. The serologic response to EB virus includes antibody to early antigen, IgM and IgG antibodies to viral capsid antigen (VCA), and antibodies to Epstein-Barr nuclear antigen (EBNA)
Epstein-Barr (EB) virus is a herpes group virus that is ubiquitous. It is the cause of classic infectious mononucleosis and is causally implicated in the pathogenesis of Burkitt lymphoma, some nasopharyngeal carcinomas, and rare hereditary lymphoproliferative disorders. The serologic response to EB virus includes antibody to early antigen, IgM and IgG antibodies to viral capsid antigen (VCA), and antibodies to Epstein-Barr nuclear antigen (EBNA).
Although most cases of infectious mononucleosis can be diagnosed on the basis of clinical findings, blood count and morphology, and a positive test for heterophile antibody, as many as 20% may be heterophile-negative, at least at presentation (Heterophile may become positive when repeated in a few days). In some of these cases, a test for Epstein-Barr virus antibodies may be useful.
The most controversial use of EBV serology is in chronic fatigue syndrome, a complaint predominantly (but not exclusively) of young to middle-aged women, characterized by long persistent debilitating fatigue and a panoply of usually mild somatic complaints. The high levels of EBV antibodies in the general population, their long persistence, and the poor correlation of antibody titers with symptoms combine to make EBV serology useless in diagnosing, following, or ruling out chronic fatigue syndrome. See table in project description.
Test Includes:
- Epstein-Barr Virus VCA Antibody (IgM), Epstein-Barr Virus VCA Antibody (IgG), Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)
Methodology
Immunoassay (IA)
Reference Range(s)
Epstein-Barr Virus VCA Antibody (IgM)
| U/mL | Interpretation |
| <36.00 | Negative |
| 36.00-43.99 | Equivocal |
| >43.99 | Positive |
Epstein-Barr Virus VCA Antibody (IgG)
| U/mL | Interpretation |
| <18.00 | Negative |
| 18.00-21.99 | Equivocal |
| >21.99 | Positive |
Epstein-Barr Virus Nuclear Antigen (EBNA) Antibody (IgG)
| U/mL | Interpretation |
| <18.00 | Negative |
| 18.00-21.99 | Equivocal |
| >21.99 | Positive |
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IMPORTANT: Discounted Labs only serves these states: Find a Location
Please read the following frequently asked questions before placing an order: FAQs
HOW DOES DISCOUNTEDLABS.COM WORK?
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Go to the "Find a Location" page to find the closest lab location. No need to make an appointment since walk-ins are welcomed. Once you have identified your closest location, go to step 2.
NOTE: We serve all states in the U.S. except New York, New Jersey, and Rhode Island. Residents of those states need a written lab order from an in-state provider. Individuals cannot obtain a blood draw in neighboring states. -
Go to "Choose a Test" and add your selection (s) in the shopping cart. If you prefer to save money on bundled tests, we have created "Lab Test Panels" that can help you decide what to order.
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If you have a discount coupon code, add it to your cart.
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A $8 lab processing fee will be added to your total.
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Pay using a credit card.
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You will receive an order confirmation and instructions email on how to download your lab request.
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Print lab request form that you downloaded.
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Take that form to the closest Quest Diagnostics location with a picture ID. Get your blood drawn.
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You will receive an email when the results are ready for you to download.
Note: You cannot place an order under someone else's profile. The profile person's name will appear on the lab order form.If you have questions, please review our FAQ Page.
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