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Vitamin D is essential for bone health and many metabolic processes. The body derives it from sunlight and food sources. Many people do not get enough sunlight or do not consume enough vitamin D rich foods. This test is important to determine if you need vitamin D supplementation or if your current supplementation is effective.

The adrenal gland produces a hormone known as dehydroepiandrosterone (DHEA). It is also made in the brain. DHEA leads to the production of androgens and estrogens (male and female sex hormones). DHEA levels in the body begin to decrease after age 30. Lower DHEA levels are found in people with hormonal disorders, HIV/AIDS, Alzheimer's disease, heart disease, depression, diabetes, inflammation, immune disorders, and osteoporosis. Corticosteroids, birth control taken by mouth, and agents that treat psychiatric disorders may reduce DHEA levels.

Pregnenolone is known as the mother hormone. All other steroids including testosterone and estrogen are derived from this important hormone. For this reason, optimal blood levels of pregnenolone are critical for a healthy hormone balance.  This test uses liquid chromatography/mass spectrometry, the most accurate assay for hormones.

Discounted Labs’ basic adrenal insufficiency panel includes cortisol, ACTH, and DHEA as a starting point. Depending on lab test results from this panel, physicians may choose to do an ACTH stimulation test, renin, potassium, and sodium. Imaging studies like a CT scan of the adrenal glands may also be considered to check for adrenal growths. In order to check for Addison's Disease, the auto-immune type of primary adrenal insufficiency, labs should be drawn to check 21-hydroxylase