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Quest Diagnostics test code 17911 is for a DNA mutation analysis of Methylenetetrahydrofolate Reductase (MTHFR). The test determines if a patient has one, two, or no copies of either of the two mutations in the MTHFR gene, C677T and A1298C.

Changes in the methylenetetrahydrofolate reductase gene can lead to certain health conditions. One of them is hyperhomocysteinemia (high blood levels of homocysteine), which is a risk factor for cerebrovascular disease, cerebral vein thrombosis, coronary artery disease, myocardial infarction, and venous thrombosis. At least 40 mutations in the MTHFR gene have been identified in people with homocystinuria, a disorder in which the body is unable to process certain amino acids properly.

Both chronically low and high levels of glutathione in the body are indicative of potentially debilitating health problems. Glutathione level is a crucial marker for many diseases, both chronic and acute. Given the importance of this protein to human health; discovering your glutathione levels could be one more way to monitor health levels, immune function, and the potential risk of diseases that have been associated with chronically low or high levels of this essential peptide.

Iodine, Serum/Plasma - Iodine is an essential element that is required for thyroid hormone production. The measurement of iodine serves as an index of adequate dietary intake and iodine overload, particularly from iodine-containing drugs such as Amiodarone.

This comprehensive panel includes key vitamins and minerals that affect quality of life and survival. Test included are: Vitamin D, Vitamin B-12, Folate (Folic Acid), Magnesium in Red Blood Cells, and Zinc in Red Blood Cells.

Vitamin D is essential for bone health and many metabolic processes. The body derives it from sunlight and food sources. Many people do not get enough sunlight or do not consume enough vitamin D rich foods. This test is important to determine if you need vitamin D supplementation or if your current supplementation is effective.

Vitamin B-12 is an essential vitamin. Low blood levels of B12 can cause: Anemia and pernicious anemia, loss of balance , numbness or tingling in the arms and legs, and weakness

A Magnesium RBC test can provide an earlier indicator of magnesium deficiency that a standard magnesium blood test. When levels are low, the body will pull magnesium from the cells to keep blood levels normal. In this case, a magnesium blood test may show normal levels while a magnesium RBC test will give a more accurate result.