Prothrombin Time (PT)

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Prothrombin Time (PT)
$21.00
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Overview

Blood test used in the evaluation of the extrinsic coagulation system; aid in screening for congenital and acquired deficiencies of factors II, V, VII, X, and fibrinogen. This test is used clinically for the therapeutic monitoring of warfarin (Coumadin®) anticoagulant therapy.

Prothrombin Time (PT) is a blood test used in the evaluation of the extrinsic coagulation system; aid in screening for congenital and acquired deficiencies of factors II, V, VII, X, and fibrinogen. This test is used clinically for the therapeutic monitoring of warfarin (Coumadin®) anticoagulant therapy.

Limitations

The PT test may not be sensitive to slight deficiencies of single factors. Heparin can extend the PT. Lupus anticoagulants may affect prothrombin time producing results that do not accurately reflect the true level of anticoagulation. The PT (and aPTT) results can be extended in patients receiving antithrombin anticoagulants such as hirudin and argatroban. These patients can be monitored for warfarin effectiveness with a chromogenic factor X assay, which is not affected by lupus anticoagulant or thrombin inhibitors.

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