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Epstein-Barr (EB) virus is a herpes group virus that is ubiquitous. It leads to infectious mononucleosis and may play a role in the development of Burkitt lymphoma, some nasopharyngeal carcinomas, and a few rare genetic lymphoproliferative disorders. Antibodies to early antigen, IgM and IgG antibodies to viral capsid antigen (VCA), and antibodies to Epstein-Barr nuclear antigen (EBNA) are all part of the EBV test.