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SHBG (sex hormone binding globulin) binds to testosterone and estradiol. High SHBG may decrease free testosterone and free estradiol.

THIS IS THE MOST AFFORDABLE TESTOSTERONE TEST IN THE U.S. The most accurate way to measure total testosterone is with liquid chromatography/mass spectrometry. This panel also shows free testosterone percent by equilibrium dialysis and free testosterone calculated from percent free T. This test is more accurate for low and high testosterone blood levels (for men who expect high testosterone blood levels over 1,500 ng/dL, women, and children who usually have low T levels). It has no interferences with supplements or anabolics. Note: Results may take 5-7 business days. For a faster turnaround, choose this test instead: Testosterone, Free, Bioavailable and Total (With Lower & Upper Limit) plus SHBG

This is the most cost effective testosterone test panel that takes the least amount of time to perform and that includes 5 important tests: 1- Total testosterone, 2- Calculated free testosterone, 3- Bioavailable (unbound) testosterone, 4- Sex hormone binding globulin (SHBG), and albumin. Testosterone upper limit under 1,500 ng/dL (ECLIA, immunoassay). It is accurate for most men using or not using TRT . For men expecting very high testosterone blood levels over 1,500 ng/dL or low total T below 250 ng/dL, the LC/MS testosterone test is more appropriate, but it takes a few more days to perform. NOTE: Despite SHBG not being listed on the lab requisition form under "Testosterone, Free, Bioavailable, and Total, Males (Adult)," rest assured the results include this critical component, as it's necessary for calculating bioavailable testosterone.

This test measures the free (unbound to SHBG or albumin) estradiol and total sensitive estradiol in blood. The test is performed using liquid chromatography/mass spectrometry (LC/MS). NOTE: This test is a send out test to Quest's Nichols Institute San Juan Capistrano.  Testing schedule is Mon and Wed.  Reports are available within 4-14 days from the time the specimen is received at the send out testing lab. Test results may take up to 16 business days.