This ultrasensitive estradiol test is recommended for men. The commonly used estradiol test may overestimate estradiol in men. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This ultrasensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation. Important note: The blood sample is sent out to Quest Diagnostics Nichols Institute San Juan Capistrano, Caifornia. Overnight delivery and testing is performed on Sunday and Friday. Reports are available within 5-7 business days from the time the specimen is collected.
SHBG (sex hormone binding globulin) binds to testosterone and estradiol. High SHBG may decrease free testosterone and free estradiol.
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