These two tests measure antithyroglobulin antibodies and Anti-TPO antibodies that are commonly present in patients with Hashimoto's thyroiditis, Graves disease and other thyroid-related conditions. Antibodies against the protein thyroglobulin can result in the destruction of thyroid cells. TPO antibodies are created when the immune system of a person targets by pure error elements of the thyroid gland or protein, leading to chronic thyroid inflammation, tissue damage, and damage to the thyroid function. Leaving this untreated may cause severe health issues. 

This test panel includes most tests needed to more deeply explore the possibility of hypothyroidism and/or Hashimoto's disease diagnosis. It includes: TSH, Free T3, Free T4, Reverse T3, Thyroglobulin Antibody and Thyroid Peroxidase Antibody (Anti-TPO). If you are taking biotin, please stop it 72 hours before the blood draw since it may interfere with hormone blood tests. A study found that TSH was suppressed in all subjects after food, so fasting may be suggested although it is not reqired by Quest. Free T4 and Free T4 values did not change significantly after eating. NOTE: Reverse T3 is analyzed using a specific technique called liquid chromatography/tandem mass spectrometry (LC/MS-MS). There's a special place in the U.S. where these precise machines needed for LC/MS panels run only on two specific days a week. So, sometimes the clock ticks a bit while we wait for samples to return from their initial collection points. Results may take 7 business days.

This Arthritis Panel Includes Sedimentation Rate, Anti-Nuclear Antibody (ANA), Rheumatoid Factor, C-Reactive Protein (CRP), and Serum Uric Acid

1. TSH (Thyroid Stimulating Hormone) Test The TSH test is crucial for diagnosing Hashimoto's disease. It gauges the level of TSH that the pituitary gland produces, which in turn stimulates the thyroid to produce T4 and T3 hormones. Elevated TSH levels can indicate hypothyroidism, commonly associated with Hashimoto's disease 

2. Thyroid Hormone Tests These tests measure the levels of free T3 (free triiodothyronine) and free T4 (free thyroxine) in the blood. A low level of free T4, along with an elevated TSH level, is a key indicator of Hashimoto's disease 

3. Thyroid Antibody Tests Most individuals with Hashimoto's disease have thyroid peroxidase (TPO) antibodies in their blood. Testing for these and other thyroid-related antibodies is a significant step in diagnosing the condition 

4. Thyroglobulin Antibody Test This test screens for antibodies against thyroglobulin, a protein in the thyroid gland. High levels are another marker of Hashimoto's disease

This osteoporosis panel includes:

• Serum total calcium, albumin (to calculate albumin adjusted calcium) and phosphorus as part of a CMP panel to detect conditions associated with hypercalcemia such as primary hyperparathyroidism or hypocalcemia and consequent secondary hyperparathyroidism causing bone loss
• Serum creatinine and estimated glomerular filtration rate (GFR) as part of the CMP panel are useful to detect renal failure which can affect bone health. 
• Serum alkaline phosphatase (ALP) as part of a CMP panel. ALP measurement is useful to detect conditions including Paget's disease, metastatic bone disease and osteomalacia, etc.
• Vitamin D nutrition should be determined by measuring serum 25-hydroxy vitamin D [25(OH)D]. Although there is controversy about the optimum level of 25(OH)D for bone health; while 50 nmol/L is considered acceptable
• Parathyroid Hormone (PTH) measurement would be required if serum calcium is abnormal, to help investigate the cause of the calcium abnormality.
• Ultra-sensitive Estradiol. Low estradiol in men and women has been linked to bone loss.
• Phosphorus. An increased phosphorus with decreased calcium suggests either hypoparathyroidism or renal disease. A decreased phosphorus and an increased calcium suggests hyperparathyroidism or sarcoidosis. When both calcium and phosphorus are decreased diagnostic considerations include malabsorption, vitamin D deficiency and renal tubular acidosis. Increased phosphorus and normal or increased calcium suggests Milk-alkali syndrome or hypervitaminosis D.

The causes of fatigue are multifactorial and could involve imbalances in several hormones. This panel includes most hormones and variables involved in the diagnosis and treatment of fatigue. Ordering this panel provides substantial cost savings when compared to ordering each test separately. The panel is useful for men and women. TESTS INCLUDED IN THIS PANEL: TOTAL AND FREE TESTOSTERONE, THYROID FUNCTION: TSH, Free T3, Free T4, Thyroid Antibodies, HEMOGLOBIN A1c, Complete Blood Count (CBC) Test (Includes white, red cells and platelets), Comprehensive Metabolic Panel (CMP), IRON, TIBC (Total Iron Binding Capacity), FERRITIN, ADRENAL FUNCTION: Cortisol and DHEA-S