Protein, Gloublin and Albumin - The major proteins seen in the serum are albumin and globulin-the latter being primarily alpha 1 and alpha 2 globulin, beta globulin and gamma globulin. Albumin accounts for more than 50% of the total serum proteins. The albumin to globulin (A/G) ratio has been used as an index of disease state, however, it is not a specific marker for disease because it does not indicate which specific proteins are altered. The normal A/G ratio is 0.8-2.0. The A/G ratio can be decreased in response to a low albumin or to elevated globulins. Total globulins may be increased in some chronic inflammatory diseases (TB, syphilis) multiple myeloma, collagen disease, and rheumatoid arthritis.  Decreased levels are seen in hepatic dysfunction, renal disease and various neoplasms.

The tests are usually ordered for patients prior to surgery to ensure normal clotting ability.  The PT and PTT Blood Tests are useful in the diagnosis of excessive, unexplained bleeding in patients who are not taking blood-thinning medications. These bleeding disorders include conditions such as nosebleeds, bruising, heavy menstrual periods, blood in the stool and/or urine, and bleeding gums, among others,

This test includes prothrombin time plus INR and it measures how long it takes your blood to clot. It’s used to monitor the effects of the medication warfarin, and can help identify possible hereditary and clotting disorders. This test does not require fasting. Prothrombin Time (PT) is a blood test used in the evaluation of the extrinsic coagulation system; aid in screening for congenital and acquired deficiencies of factors II, V, VII, X, and fibrinogen. This test is used clinically for the therapeutic monitoring of warfarin (Coumadin®) anticoagulant therapy.

The pre-op (surgery) blood test includes the three test panels (CBC, CMP, and Prothrombin Time Test) most commonly ordered before a person has surgery. Pre-operative testing is usually done during the few days before the surgery. This panel lets your surgeon know what to be aware of in case of complications during surgery.