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Although testosterone frequently overshadows estradiol, a hormone more commonly associated with women, estradiol plays a significant role in men's health. Derived from testosterone through a process known as aromatization, estradiol contributes to various physiological aspects in men. Although it's crucial for maintaining bone density, its role in sexual health, body composition, and other health parameters is subject to ongoing discourse. Here, we delve into the dynamics of estradiol in men, its implications, and the importance of accurate measurement. Understanding Estradiol in Men The hormone estradiol, although present in smaller quantities in men compared to women, is produced through the aromatization of testosterone in liver, fat, and other cells. This conversion is nature’s design, hinting at a purpose behind it. Besides promoting bone health, estradiol’s influence on men's libido, body composition, and other factors is a hot topic among researchers. Excessive levels of estradiol, especially alongside low testosterone levels, could lead to conditions like gynecomastia (enlarged breasts in men). Hormonal Balance: The HPT Axis The Hypothalamic-Pituitary-Testicular (HPT) axis is a hormonal cascade that adjusts testosterone production based on the levels of testosterone and estradiol in the body. When either hormone level goes up too high, the HPT axis responds by decreasing the production of testosterone to keep hormone levels in balance. Aromatase Inhibitors: Boon or Bane? Aromatase inhibitors (AIs) stop the production of estradiol and are often given to people who are getting testosterone replacement therapy (TRT) to help them look younger and stay healthy. While higher estradiol levels could potentially cause gynecomastia and water retention, there's speculation, albeit without scientific backing, linking high estradiol levels to erectile dysfunction. The use of AIs is thought to mitigate these issues by lowering estradiol levels. However, the exact threshold of estradiol levels in men, beyond which it could be detrimental, remains undefined. Unveiling the Optimal Range Recent studies have started to shed light on estradiol's optimal range. For instance, levels below 20 pg/ml have been associated with increased bone loss, higher fat mass, and diminished sexual function in men. It is very important to get a correct reading of estradiol, and it is better to use a sensitive estradiol test (LC/MS assay) instead of the more common ECLIA-based test to avoid getting wrongly high estradiol readings from things like CRP (C-reactive protein). Estradiol’s Diverse Effects: A Closer Look 1. Bone Density: A study showed that estradiol levels below 11 pg/ml were linked to increased bone loss in men, emphasizing estradiol's role in bone health (Source). 2. Libido and Erectile Function: One groundbreaking study revealed that lower estradiol levels were correlated with increased body fat and a decrease in sexual desire and erectile function (Source). 3. Mortality Rate: A study highlighted that men with estradiol levels either below 21.80 pg/ml or above 30.11 pg/ml had a higher mortality rate, indicating a potential sweet spot for estradiol levels (Source). 4. Testosterone Therapy: In men undergoing TRT, elevated estradiol levels were associated with heightened libido, suggesting a nuanced interplay between testosterone and estradiol (Source). Conclusion The journey to demystify estradiol's role in men is ongoing. While its importance in bone health is well acknowledged, the hormone's broader impact on male physiology is gradually being unraveled. Accurate estradiol measurement and a deeper understanding of its optimal range could pave the way for enhanced men's health management, particularly for those undergoing testosterone replacement therapy.     Here is a more detailed discussion on estradiol in men: Click here   How to Get a sensitive estradiol test  

Table of Contents The 6 Most Popular Discounted Lab Panels Online Why Using Direct-to-Consumer Labs? How Do Online Lab Tests Work? What Lab Tests Can You Choose? What Are the Most Popular Blood Tests Online? 1. Heavy Metal Test Symptoms of Heavy Metal Poisoning 2. Hormone and Wellness Panels for Men and Women 3. Comprehensive Fatigue Panel 4. Erectile Dysfunction ED Panel 5. Electrolyte Panel 6. Elite Male Blood Test Panel Get Your Blood Test Today! The 6 Most Popular Discounted Lab Panels Online   According to the World Health Organization, chronic diseases kill millions of people each year. Diabetes alone accounted for nearly 1.6 million deaths in 2015. Deaths caused by neurodegenerative diseases such as dementia doubled since 2000, and this number is expected to grow in the upcoming years. Although these are alarming facts, you might be happy to find out that numerous diseases and injuries, particularly chronic illnesses, can be prevented. To prevent a disease, you first need to be aware of it. To be aware of it, you need to do the right thing and get your health checked periodically. Discovering a predisposition to the disease earlier on gives you a massive advantage. You’ll be able to follow special treatments and minimize its risks or eliminate them. But how to get tested for various diseases which might affect you? Well, one of the simplest and most efficient ways is by using direct-to-consumer labs. These are usually discount labs you can purchase online at affordable prices and have your general health checked in a matter of days. Why Using Direct-to-Consumer Labs? Direct-to-consumer labs are discounted labs sold by various companies such as DiscountedLabs.com. Many people decide to buy their lab tests instead of working with their primary physicians because this route offers numerous advantages. For example: You can choose your preferred test from hundreds of labs available online You save money since you eliminate the middle man and buy "directly from the source” and not having to pay for a doctor’s visit copay. You get your results back in just a few business days.  Your information and results are confidential and secure You can draw blood or offer a urine sample in the nearest clinic from your house You have more control over your health More and more people are taking advantage of this opportunity to buy a cheap blood test and become more aware of their health, so why shouldn’t you? How Do Online Lab Tests Work? Getting a blood test online is not rocket science. The procedure has just a few steps: 1. Order your preferred test from DiscountedLabs.com 2. Get a form which allows you to go to the nearest lab or clinic to draw blood that you can download after your purchase. 3. Have your blood samples analyzed by a Quest Diagnostics laboratory in your state or the nearest state. 4. The results will be available for you to download in 5-7 business days from the day of your lab blood draw. 5. You can visit your doctor to help you interpret these results or compare them against reference values you find online As you can see, the process is simple, confidential and secure. You don’t even have to visit your doctor for a prescription since DiscountedLabs.com provides that for you. What Lab Tests Can You Choose? There are numerous things you can test in a human body using just a blood, urine or saliva sample. For example, some of the most popular tests include a complete blood count test which tells you how much hemoglobin there is in your blood, the number, and type of your blood cells, etc. You can also go for a pregnenolone test or a cheap testosterone test to determine your testosterone levels. Cheap blood tests are also available, and they can show information about your cholesterol levels, triglycerides, inflammation biomarkers and more. Buying a testosterone test online is increasingly popular especially if you’re a bodybuilder and you want to monitor your T levels or if you think you have testosterone deficiency. DiscountedLabs.com offers dozens of affordable tests for both men and women, so you have a lot of options at your disposal when it comes to taking care of your health. What Are the Most Popular Blood Tests Online? If you’re buying for the first time and you don’t know what to focus on, keep reading to find out a list of some of the most popular direct-to-consumer labs you can buy today. These tests can be obtained using a discounted labs coupon to help you save some money in the process. Here is a way to compare all discounted lab panels to see which one is best for you. 1. Heavy Metal Test The dangers of having heavy metals in your body are real. The heavy metals category includes mercury, arsenic, cadmium, lead and other types of toxic substances. These elements can stick to your bones and organs, causing serious health problems in the long run. The body can easily eliminate trace amounts of heavy metals regularly. However, if you get too high of a quantity of arsenic, for example, you're exposed to serious health risks. Lead is one of the most poisonous heavy metal out there. It can cause brain damage, depression, anxiety, and even panic attacks. Testing for heavy metals can be done using a single blood sample or a urine sample. The Heavy Metals Profile I is performed using a blood sample, and it determines the levels of arsenic, mercury, and lead in your body. There are two more tests sold by DiscountedLabs such as the heavy metal profile II and the urine test. These also come at affordable prices and allow you to discover the levels of cadmium, lead, and arsenic in your system. Symptoms of Heavy Metal Poisoning Having a high amount of toxic metals in your body puts you in a risky situation, so you need to see your doctor immediately if this happens. Moreover, you’ll be able to experience certain symptoms along the way, and you shouldn’t ignore them. These symptoms depend on the type of metal which caused the poisoning. For example, these symptoms are common among people: l Stomach pain l Diarrhea l Nausea l Dizziness l Tingling in your feet l Weakness and headaches l Vomiting Some of these symptoms are your body's desperate attempt to eliminate the accumulated heavy metals. Help your body by getting tested for heavy metals immediately and find out if you're at risk. 2. Hormone and Wellness Panels for Men and Women Any hormonal imbalance you might experience can drastically influence your health. For example, testosterone deficiency can lead to poor sex drive and even symptoms of anxiety and depression in men of all ages. Instead of looking for “testosterone testing near me” on Google, you can order a testosterone test online and have your hormonal levels checked quickly. In women, estrogen levels are the most important. One of the most popular estrogens is estradiol. This hormone directly influences mood, cognition, sex drive, libido, and other functions in women. It is also possible to check the estradiol levels for men and see if they are elevated. Very high estradiol levels in men might be caused by testosterone replacement therapy. This is a rare but known side effect of TRT, but it can be minimized with certain medications. Another common side effect of TRT has high hematocrit. If you’re wondering what high hematocrit mean then you should know that this is the percentage of red blood cells in the blood. An elevated hematocrit might cause various health problems in the long run. Donating blood can be the answer if you’re wondering how to lower hematocrit on TRT, donating blood can be the answer. However, you shouldn’t donate blood more often than one or two times per year because this can lower your ferritin levels which causes anemia. There are high hematocrit symptoms to which you should pay attention. For example, having high hematocrit levels can lead to: l Fatigue l Itching l Bone pain l Blurred vision l Excessive sweating As you can see, there are numerous important hormones you need to be mindful of such as testosterone, estrogen, estradiol, ferritin, etc. A complete hormone and wellness panel can make your life easier because it provides a complete overview of your health. DiscountedLabs.com sells a Complete Hormone & Wellness Panel for MEN and a Hormone & Wellness Panel for WOMEN, so pick the one suitable for you to learn more about your hormonal health. 3. Comprehensive Fatigue Panel If you feel tired after a long day at work, it’s normal to be so, especially if you also found some time to visit a local gym for half an hour. However, if you constantly feel tired, even in the morning when you wake up, then this is not normal. Diagnosing excessive fatigue is not that easy. There are numerous potential causes which need to be analyzed independently. For example, here are a few factors which might directly influence your energy levels and how tired you feel regularly: l Your thyroid function l Whether you have hyperglycemia or hypoglycemia l Your total and free testosterone levels l The amount of iron in your blood cells l The number of red blood cells in the blood l Any adrenal problems you might have One hormonal imbalance in these areas can make you feel excessively tired. Also, keep in mind that such health problems don’t get corrected on their own. You need to do a thorough health checkup and see what causes your tiredness. A comprehensive fatigue panel takes all these factors into account and analyzes multiple hormones and substances in your bloodstream. Based on the results, your doctor can make appropriate health recommendations. For example, people who have low energy levels as a result of insufficient iron in their bloodstream might need to take an iron supplement. Similarly, those who have low testosterone levels might benefit from TRT or various lifestyle changes to improve their total and free testosterone levels. 4. Erectile Dysfunction ED Panel Another commonly purchased panel is the ED blood test. Unfortunately, the prevalence of erectile dysfunction is quite high, especially among men who are 40 years old or older. However, this health condition can be treated in numerous ways. There are both invasive and non-invasive procedures as well as pills which can improve the symptoms of erectile dysfunction. Certain lifestyle changes can also improve one's erection. However, the most important thing is to know exactly what caused the ED and how to treat it efficiently. For example, having low testosterone levels can lead to erectile dysfunction in men of all ages. In this case, TRT might be the appropriate treatment method to improve libido. Similarly, high estradiol can also be linked to erectile problems. Estradiol is a female sex hormone. If there is too much (or even too little) estradiol in the bloodstream, the person in question will experience erectile dysfunction. ED can also be caused by thyroid problems. For example, the TSH, T3, and T4 are all thyroid hormones which directly influence the production of testosterone and sex drive in general. If these hormones are out of balance, one might not be in the mood for sex that often. Prolactin is another important hormone in the body. It is produced by the pituitary gland, and if it’s not secreted correctly, ED can appear in men. As you can see, there are numerous factors which influence sex drive. The Erectile Dysfunction Panel which can be bought from DiscountedLabs.com looks at all these hormones to determine which one is out of balance. All you need to do is to buy the panel online and go to your nearest lab for a blood sample. The results will be communicated to you in a few business days, and then you can begin looking for appropriate solutions to your ED problem. 5. Electrolyte Panel Electrolytes are important substances in the human body. The most popular ones are potassium and sodium. Other electrolytes include chloride and carbon dioxide. The job of electrolytes is to regulate important bodily functions such as maintaining correct blood pH, muscle and nerve function. When electrolytes go out of balance, various physical symptoms can appear. For example, too much sodium in the body makes the blood acidic. This can lead to chronic illnesses in the long run. At the same time, too much potassium can cause heart problems and other similar health conditions. The Electrolyte Panel which can be bought from DiscountedLabs.com looks at four different important electrolytes in the body such as carbon dioxide, chloride, potassium, and sodium. This is one of the most affordable blood tests online, and it requires only a small blood sample to run it. 6. Elite Male Blood Test Panel If you want to have a broader overview of your health, the Elite Male Blood Test Panel is highly recommended for you. This is one of the most comprehensive panels sold on DiscountedLabs and one of the most affordable in the United States. Using just a simple blood sample, you get to find out more information about multiple hormones, enzymes, and substances in your body such as testosterone, prolactin, thyroid hormones, IGF-1, PSA and more. This panel looks at more than ten different hormones in your bloodstream, helping you diagnose certain conditions or preventing more serious diseases. A lipid panel is also included in this package, revealing information about your good cholesterol, bad cholesterol, and triglyceride levels. Another important hormone checked by this panel is sensitive estradiol. This hormone is linked to sex drive, and if it is in high quantities, it can lead to gynecomastia which is also known as “male boobs.” The estradiol levels might increase as a result of testosterone replacement therapy. If you’re currently using TRT, you might want to get this panel to find out if you’re prone to develop gynecomastia in the future. The Elite Male Blood Test Panel also looks at your complete blood count. It analyzes your hematocrit, the number of red blood cells, the amount of hemoglobin in your bloodstream, etc. Knowing more information about red blood cells helps you determine if you’re predisposed to anemia. Similarly, having a high hematocrit can cause problems in the long run so that you can monitor this important parameter with the Elite Male Panel. Another important aspect checked by this panel is the metabolic function. More precisely, the test looks at the kidney and liver health. As you probably already know, your liver is one of the most important organs in the body. It is responsible for eliminating toxins and producing numerous hormones required for a healthy living. Once you know the state of your liver, you'll be able to make appropriate lifestyle changes to improve its function. The same story goes for your kidneys. For example, creatinine is a byproduct which needs to be excreted by the kidneys. If this process doesn't happen correctly, you can develop kidney problems in the future. The Elite Male Blood Panel helps you look at all these vital aspects and have a broader understanding of your health. Get Your Blood Test Today! As you can see, ordering direct-to-consumer labs is efficient, more affordable and saves time. You don’t have to search for “discounted labs tests near me” on Google anymore; the answer comes directly from DiscountedLabs.com.  

It is suggested that you talk to your physician about the need for proper blood tests before and during testosterone. Read this first since it is the most common testosterone side effect: High hematocrit Problem Solution and Comments Acne/oily skin Caused by Dihydrotestosterone (DHT) effect on increased oil production · Accutane– a powerful prescription item - 40 mg/day for one week sometimes stops acne if started at the first sign or as directed by your doctor. Accutane is potentially highly liver toxic and can lower testosterone. Do not use unless as last resort. · Sporanox – Effective for some acne-like eruptions that are caused by fungi. Some doctors also prescribe antibiotics, like tetracycline, for acne with good results. . Minocycline . Shower with Nizoral shampoo· Anti-bacterial soaps - Use a scrubbing brush and wash twice a day, especially after sweating during a workout. · UV light or sunlight with moderation. . Zinc/copper supplements or zinc soaps may help some men with acne. . Other options: How to treat and prevent acne Hair loss Caused by DHT effect on hair follicles · Nizoral shampoo– Available by prescription and over-the-counter as a lower dose product. · Rogaine – Available over the counter · Propecia (finasteride) - Available by prescription. A few males experience decreased erections with finasteride. Do not use. Increased sex drive · A problem? Sex drive is part of quality-of-life. This is not necessarily a bad side effect. Enjoy it. Unresolved erectile function · ED Drugs– Available by prescription; enables robust erections. If you have sinus congestion or headaches/backaches take non-drowsy allergy medication and ibuprofen. ED drugs can be combined with alpha-blockers and/or nitric oxide precursor amino acids (arginine or citrulline) · Yohimbine (Yocon) - Available by prescription; increases sex organ sensitivity. Can increase heart rate and blood pressure · Muse - Available by prescription; pellet inserted into the urethra to produce an erection. Unpopular · Trimix – Available by prescription from compounding pharmacies. The best and cheapest formula for injection into the penis for lasting erections. · Caverject - Available by prescription. An injection into the penis that produces an erection that can last 1 to 2 hours. Be careful with injecting too much since it can produce dangerously ling erections that need to be treated in emergency rooms! Follow instructions from your urologist. · Papaverine – An older injectable medication, less expensive than Caverject. · Wellbutrin – Prescription at 300 to 450 mg/day; increases dopamine. · Human chorionic gonadotropin (HCG) – First dose is 2,000 IU, then 250-500 IU twice or three times a week. No protocol has been proven in controlled studies yet. Insomnia Usually, this is caused by dosages that are too high. Find the least amount that gives you a good result. · Sleeping medications – e.g. Ambien, Sonata, Lunesta, Restoril · Melatonin- 1 to 3 mg before bedtime. If you wake up groggy after 6 hours your dose should be lower. · Avoid working out too close to bedtime. · Limit caffeine, especially after 3 pm. · You may want to try a sleep formula with tryptophan, melatonin, and magnesium. Nutrients do not work as well as drugs, but they can help some people. Article: How to protect your circadian rhythm Sleep Apnea · Have your doctor prescribe a sleep study if you snore and wake up tired even after 7 hours of sleep. Some people may have to wear a C-PAP machine to breathe at night. Visit Home - SleepApnea.org for more information. There are also oral devices for those people who fail CPAP. Fatigue- When Testosterone Is Not Enough Testicular atrophy · Human Chorionic Gonadotropin (hCG)– One 2,000 unit injection per week for 2 weeks, followed by maintenance of 350-500 IU twice a week. For men who want to remain fertile while on TRT, 500 IU every other day has been studied. Watch this video on hCG and men Enhanced assertiveness or reactivity. · Make sure you are getting enough sleep. . Count until 10 and be aware of your interaction with others. · Decrease caffeine. · Meditation, mindfulness, yoga, breathe from your belly for a few minutes when overreacting. · The testosterone dosage may be too high. · Ask yourself: Do I need to always be right? . Vent extra energy at the gym, sex, and sharing with your buddies at www.excelmale.com High blood pressure: Can be caused by sodium retention, high hematocrit, being overweight, and other factors · Blood pressure medications - Elevated blood pressure may be transient or not. Try ACE or ARBs since they seem to have fewer sexual dysfunction related effects.  · Magnesium (600 mg/day); vitamin B6 (100 to 200 mg/day); may help reduce water retention. · Water - Drink extra water every day to help flush the kidneys. . Make sure you are doing cardio exercise at least 3 times a week for 30 min. Sweat and lower your salt intake since TRT increases sodium retention in some men. Gynecomastia- RARE in TRT (male breast development) Caused by overproduction of estrogen in the presence of low testosterone and high IGF-1 · Arimidex Inhibits estrogen production. Available by prescription. 0.5 mg/week max. Ensure that your estradiol is never under 20 pg/ml (by sensitive test) since it is needed for bone, skin, brain, lipids, libido, good lipids and hair health. Only 0.3-0.4% of testosterone is aromatized to estradiol. Current lab ranges were derived from men not on TRT. Most men on TRT do not need anastrozole. Be careful not to crash your estradiol. · Nolvadex (tamoxifen)– Competes with estrogen for receptors. Available by prescription, 10 to 20 mg/day. Use of Nolvadex during a steroid cycle may reduce the net anabolic effect, as it decreases the production of GH and IGF-1.  . Severe cases may require removal of the breast tissue by surgery. · DHT cream- Some people have obtained great results by rubbing a 10% DHT cream on their nipples. Not available in the US but some people order it online from Germany . Read about medications/foods to avoid if you have gynecomastia. . Those who do know to respond to the above, check other reasons Watch this video about estradiol in men Check your estradiol with the right sensitive test. To find out how long it takes testosterone replacement to potentially show benefits, read this article. For affordable blood tests in most cities in the U.S. (Prescription provided): DiscountedLabs.com We also highly recommend reading this and other articles from our friend Lee Myers from peaktestosterone.com : Testosterone Risks Metzger, DL, et al. Estrogen receptor blockade with tamoxifen diminishes growth hormone secretion in boys: evidence for a stimulatory role of endogenous estrogens during male adolescence. J Clin Endocrinol Metab (1994) 79(2):513-518. [ii] el-Sheikh, MM, et al. The effect of Permixon (saw palmetto) on androgen receptors. J Acta Obstet Gynecol Scand (1988) 67(5):397-399. [iii] Suzuki, K, et al. Endocrine environment of benign prostatic hyperplasia: prostate size and volume are correlated with serum estrogen concentration. Scand J Urol Nephrol (1995) 29:65-68. [iv] Gann, PH, et al. A prospective study of plasma hormone levels, nonhormonal factors, and development of benign prostatic hyperplasia. The Prostate (1995) 26:40-49.   Buy testosterone tests on DiscountedLabs.com

The Best Illustrated Testosterone Book Now Available on Amazon Nelson Vergel, a well-known author of men’s health and hormone books, has published his fourth testosterone book, Beyond Testosterone. Nelson Vergel holds a chemical engineering degree and an MBA. After an HIV diagnosis over 33 years ago, he explored therapies to reverse wasting syndrome to save his life and those of his peers, leading him to co-author “Built to Survive: The Clinical Use of Anabolic Steroids for HIV+ Men and Women”,” a book that became the leading wasting treatment guide in the HIV field. He has been a member of several NIH and pharmaceutical advisory groups and FDA review panels. Nelson also founded the Body Positive Wellness Clinic and Program for Wellness Restoration in Houston, providing health education and services to HIV+ people. To expand help to the general population, he wrote “Testosterone: A Man’s Guide” and created ExcelMale.com and DiscountedLabs.com to provide men’s health education and access to affordable blood testing. His latest project aims to improve access to testosterone and hormone replacement treatments around the world by providing the largest physician directory in the world. About the Book: Beyond Testosterone This 427-page illustrated book covers all aspects of testosterone replacement therapy, including the basics of testosterone, testosterone in women, and how to increase testosterone levels naturally. It also covers the diagnosis of low testosterone and the different treatment options available by prescription in the United States and around the world. Moreover, "Beyond Testosterone" goes in-depth on the benefits of testosterone replacement therapy, side-effect management, and the effects of testosterone on the prostate and cardiovascular system. The book also reviews the uses of human chorionic gonadotropin (HCG) and discusses whether estradiol is an enemy or a friend of men. It covers the use of anastrozole and how to prevent and treat gynecomastia, acne, hair loss, water retention, high blood pressure, erectile dysfunction, and low libido. It also explores the clinical use of FDA-approved anabolic steroids for different conditions, like wasting and other diseases. Furthermore, "Beyond Testosterone" provides information on fertility and HPTA recovery after anabolic steroid use or after stopping testosterone treatment. It also covers growth hormone-releasing hormones, DHEA supplementation, thyroid dysfunction diagnosis and treatment, and maintaining good mental health. Additionally, it provides tips on nutrition for muscle gain and fat loss, exercise, and how to monitor TRT lab tests. Lastly, the book includes a section on slack testosterone in Spanish, interviews with different experts, and resources. This book is an excellent resource for men who are considering testosterone replacement therapy or are already on TRT. It is a comprehensive guide that provides information on all aspects of TRT, from diagnosis to treatment to recovery. With "Beyond Testosterone," men can have a better understanding of their options and make informed decisions about their health.    Beyond Testosterone: Book Contents Introduction How to Use This Book Testosterone 101 Testosterone in Women How to Increase Testosterone Naturally Benefits of Testosterone Replacement Diagnosis of Hypogonadism (Low Testosterone) Testosterone Treatment Options Testosterone Side Effect Management Testosterone and the Prostate Testosterone and the Cardiovascular System Human Chorionic Gonadotropin (HCG) Estradiol: The Other Male Hormone Gynecomastia: Not a Simple Diagnosis Dihydrotestosterone: Should We Be Concerned About This Testosterone Metabolite? TRT-Related Acne and Hair Loss TRT-Related Water Retention and High Blood Pressure Erectile Dysfunction/Low Libido Clinical Use of FDA-Approved Anabolic Steroids Fertility and HPTA Recovery Growth Hormone-Releasing Products Thyroid Dysfunction: Diagnosis and Management Mental Health Nutritional Considerations Exercise Considerations Nelson's Tips for TRT Patients How to Monitor TRT Lab Tests La Testosterona: Información en Español Expert Interviews TRT Resources "Beyond Testosterone" is more than a medical guide; it's a tribute to the collective wisdom of the ExcelMale.com community, capturing the essence of community-driven health discussion. Each topic is enhanced with QR codes for updated information and practical tips, making it a dynamic tool for anyone seeking to understand the broader implications of testosterone in health. This book is indispensable for patients exploring testosterone therapy and clinicians aiming to enhance their therapeutic practices. It promises to empower readers with knowledge and inspire them to take charge of their health. Click here to buy: Beyond Testosterone by Nelson Vergel Click here to buy: US: Buy Now Canada: Buy Now UK: Buy Now Australia: Buy Now Spain: Buy Now Germany: Buy Now ALSO AVAILABLE ON THESE DEVICES FIRE TABLETS Fire HD 8 (8th Generation) Fire 7 (9th Generation) Fire HD 10 (9th Generation) Fire HD 8 (10th Generation) Fire HD 10 (11th Generation) Fire HD 10 Plus Fire 7 (12th Generation) Fire HD 8 (12th Generation) Fire HD 8 Plus   FREE KINDLE READING APPS Kindle for Android Phones Kindle for Android Tablets Kindle for iPhone Kindle for iPad Kindle for Mac Kindle for PC Kindle for Web

Are you a bodybuilder looking to maximize your performance and ensure optimal health? Regular bodybuilding blood work is key to achieving these goals. It provides valuable insights into your body's functioning, allowing you to make informed decisions about your training, nutrition, and supplementation. In this blog, we will explore the importance of regular blood work for bodybuilders and how it can help you strike the right balance between performance and health. We'll also address common factors that can affect blood test values in bodybuilders, as well as essential lab tests that every bodybuilder should consider. Don't miss out on this valuable information that can take your bodybuilding journey to new heights. Table of Contents The Importance of Regular Bodybuilding Blood Work Maximizing Performance and Health: A Balance Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care Factors that Affect Blood Test Values in Bodybuilders Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Resistance Exercise Can Increase Liver Enzymes Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol High Doses of Anabolics Can Decrease Ferritin in Bodybuilders Understanding Essential Bodybuilding Blood Work Tests Complete Blood Count (CBC) Hematocrit Comprehensive Metabolic Panel (CMP) Lipid Test Panel Cystatin C with EGFR Kidney Test eGFR Kidney Test GGT Liver Test Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Free Testosterone (Equilibrium Ultrafiltration) Test Ultra-Sensitive Estradiol (E2) Test Prolactin Test DHT Test IGF-1 Test Ferritin Test How do these tests help optimize bodybuilding performance? The role of these tests in muscle gain, fat loss, and quality of life How can bodybuilders prepare for these tests? Why is regular bodybuilding blood work essential? How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com Conclusion   The Importance of Regular Bodybuilding Blood Work Regular bodybuilding blood work plays a crucial role in monitoring hormone levels and overall health, including high blood pressure. By conducting regular blood tests, bodybuilders can identify potential health issues before they become serious. Additionally, blood work provides valuable insights for optimizing nutrition and supplementation, leading to better performance. Tracking blood markers allows bodybuilders to make informed decisions about their training and recovery strategies. Ultimately, regular blood work is essential for long-term health and longevity in the world of bodybuilding. By staying on top of blood markers like testosterone, hormone levels, glucose, and kidney function, bodybuilders can ensure they are in optimal condition to achieve their goals. Maximizing Performance and Health: A Balance Regular monitoring of bodybuilding blood work, including testosterone tests, is crucial for bodybuilders to maximize their performance and maintain good health. Through regular blood tests, bodybuilders can monitor hormone levels, nutrient deficiencies, and overall organ function. This information is invaluable in making informed adjustments to diet, supplements, and training routines. By maintaining a balance between performance and health, bodybuilders can optimize their training and achieve their goals. Prioritizing health through regular blood work is essential for long-term success and sustainable progress in bodybuilding. It allows bodybuilders to identify any potential imbalances and make the necessary adjustments for optimal performance. By utilizing comprehensive metabolic panels, lipid panels, and hormone level tests, bodybuilders can ensure that their training is effective and their bodies are functioning optimally. Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses   According to a scientific review, the use of anabolic steroids has the following ergogenic effects: ■ Increase in lean body mass ■ Increase in muscle cross-sectional area ■ Decrease in body fat percent ■ Increase muscle strength & power ■ Enhance recovery between workouts ■ Enhance recovery from injury ■ Increase in protein synthesis ■ Increase in muscle endurance ■ Increase in erythropoiesis, hemoglobin, and hematocrit ■ Increase in bone mineral density ■ Increase in glycogen storage ■ Increase in lipolysis ■ Increase in neural transmission ■ Reduced muscle damage ■ Increase in pain tolerance   However, the use of these agents could have the following side effects: Cardiovascular ■ Lipid profile changes ■ Elevated blood pressure ■ Decreased myocardial function Increased in blood viscosity due to high hematocrit Dermatological ■ Acne ■ Male pattern baldness Endocrine ■ Gynecomastia ■ Decreased sperm count ■ Testicular atrophy ■ Impotence and transient infertility Hepatic ■ Increased liver enzymes Renal Decreased kidney function Genitourinary Males ■ Reduced sperm counts ■ Decreased testicular size Females ■ Menstrual irregularities ■ Clitoromegaly ■ Masculinization Males and Females ■ Gynecomastia ■ Libido changes Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care The stigma surrounding performance-enhancing drugs (PEDs) frequently makes bodybuilders reluctant to seek medical attention. Many bodybuilders are reluctant to disclose their PED use due to fear of judgment or a lack of understanding from healthcare professionals. This can impede their access to important resources such as regular blood work, which is vital for monitoring health and performance. Healthcare professionals need to be knowledgeable about the potential risks and side effects associated with PEDs in order to provide appropriate care and guidance. Open communication and support between bodybuilders and healthcare professionals can foster collaboration for optimizing performance while minimizing health risks.   Factors that Affect Blood Test Values in Bodybuilders Muscle damage and inflammation can impact blood test results in bodybuilders, as the body's response to intense training can cause temporary changes in certain blood markers. Additionally, high protein intake, which is common among bodybuilders, may affect kidney function and liver enzymes but is not clinically significant, which is concerning to doctors not familiar with this fact. Steroid use can also lead to hormonal imbalances and abnormal blood test results. Dehydration, which can occur during intense workouts or when bodybuilders are cutting weight, can cause changes in electrolyte and blood cell levels. Weight training can also increase certain live enzymes in a non-clinical way. Supplements like creatine can falsely increase serum creatinine, which can alarm certain physicians. It is important for bodybuilders to address any nutritional deficiencies identified through blood testing, as these deficiencies can impact performance and overall health. Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Anabolic steroid use without testosterone can result in a decline in testosterone levels among bodybuilders, leading to low testosterone, or TSH. Testosterone plays a crucial role in muscle growth, recovery, and overall performance in bodybuilding. To ensure optimal health and performance, bodybuilders should regularly monitor their testosterone levels. Consulting with a healthcare professional can help them effectively manage their hormone levels. It is essential to maintain balanced testosterone levels to avoid negative side effects and maximize results. By being proactive in monitoring testosterone levels, bodybuilders can optimize their performance and achieve their desired outcomes. Resistance Exercise Can Increase Liver Enzymes Intense resistance exercise can result in temporary elevations in liver enzymes, including alkaline phosphatase, which is a normal response to muscle damage and repair. It is crucial for bodybuilders to inform their healthcare provider about their exercise routine before getting blood work done. Although elevated liver enzymes due to exercise are typically harmless and resolve on their own, regular monitoring of liver enzymes is essential for bodybuilders to ensure optimal health and performance. By keeping track of liver enzyme levels, bodybuilders can identify any abnormalities early on and take appropriate actions to maintain their liver function. Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Creatine supplementation can temporarily decrease kidney function markers, leading to lower creatinine and potassium levels in bodybuilders. It is important for bodybuilders to inform their healthcare providers about any dietary supplements before undergoing blood tests. Once creatine supplementation is discontinued, creatinine and potassium levels can normalize. However, monitoring kidney function through multiple biomarkers is essential for an accurate assessment. By incorporating these measures, bodybuilders can ensure that their kidney function is accurately evaluated. Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol Certain oral anabolic steroids used by bodybuilders have the potential to increase liver enzymes and decrease HDL cholesterol levels, leading to an increase in total cholesterol and low-density lipoprotein. Regular blood tests are vital for bodybuilders who use these oral steroids to monitor their impact on liver function and cholesterol levels. Elevations in liver enzymes can be a sign of liver damage, while decreased HDL cholesterol levels pose a risk for cardiovascular health. Working with a healthcare professional is essential to mitigating these potential risks associated with the use of oral anabolic steroids. By closely monitoring liver health and cholesterol levels, bodybuilders can make informed decisions about their supplementation and take necessary steps to protect their overall health. High Doses of Anabolics Can Decrease Ferritin in Bodybuilders High doses of anabolic steroids can result in decreased ferritin levels among bodybuilders, impacting their overall performance. Ferritin plays a crucial role as a protein that stores iron, and deficiencies can have negative effects on muscle growth and health. To optimize supplementation and monitor ferritin levels, regular blood tests are essential. Consulting with a healthcare professional can provide personalized guidance on maintaining optimal ferritin levels and growth hormone levels. It is important for bodybuilders to be aware of the potential impact of high doses of anabolic steroids on ferritin levels and take proactive measures to ensure balanced hormone levels and nutrition. By prioritizing the monitoring of ferritin levels, bodybuilders can support their muscle growth and overall well-being. Understanding Essential Bodybuilding Blood Work Tests Regular blood work is vital for bodybuilders to monitor their health and optimize their performance. Key lab tests for bodybuilders include hormone levels, liver function, kidney function, and thyroid function. These tests can help identify potential health issues and allow for adjustments in training and nutrition plans. Working with a healthcare professional who specializes in sports medicine or bodybuilding is beneficial to ensure an accurate interpretation of the results. By regularly monitoring hormone levels, such as testosterone and estradiol, bodybuilders can address any imbalances and make necessary adjustments to their supplementation or hormone replacement therapy. Additionally, liver function tests like ALT and AST can assist in identifying any liver abnormalities or damage that may result from the use of anabolic steroids. Kidney function tests, like creatinine and BUN, are crucial for assessing the impact of intense training and supplement use on the kidneys. These lab tests provide valuable insights into a bodybuilder's health and play a crucial role in maintaining optimal performance, including CMP. Complete Blood Count (CBC) A complete blood count (CBC) test panel measures several components of your blood, including Red blood cells, which carry oxygen, White blood cells, which fight infection; hemoglobin, the oxygen-carrying protein in red blood cells; hematocrit, the proportion of red blood cells to the fluid component in your blood (which is correlated with blood thickness); and Platelets, which help with blood clotting. Hematocrit All androgens, like testosterone and AAS, can increase red blood cells and their proportion in the blood (hematocrit), increasing blood thickness (erythrocytosis). High hematocrit can cause high blood pressure, headaches, and cardiovascular risks. This panel is essential since it determines when you reach a hematocrit of 53, indicating that blood donation or therapeutic phlebotomy is needed. Comprehensive Metabolic Panel (CMP) The comprehensive metabolic panel, or CMP panel, consists of 14 blood tests that are an initial medical screening tool to review overall health. The CMP blood test panel checks for glucose, kidney function, liver function, electrolytes, and fluid balance. Fasting IS REQUIRED. Lipid Test Panel This panel includes LDL (bad cholesterol), HDL (good cholesterol), and triglycerides (fatty acids dissolved in the blood). Higher doses of T and AAS can increase LDL and decrease HDL and triglycerides. Severely decreased HDL may cause cardiovascular issues in the long term. FASTING IS REQUIRED. Cystatin C with EGFR Kidney Test Since higher muscle mass, protein intake, and creatine supplementation can all affect creatinine as the primary variable, cystatin C is a more accurate way to assess kidney function in people with higher muscle mass. Another one of the measures of kidney function is the estimated glomerular filtration rate (eGFR). The glomerular filtration rate describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCRCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit of time and is a useful measure for approximating the GFR. eGFR under 60 may indicate issues that are affecting kidney function. eGFR Kidney Test The eGFR kidney test is an important tool for bodybuilders to monitor their kidney health and ensure optimal performance. By measuring how well the kidneys are functioning, this test can help detect any potential kidney issues that may arise, affecting metabolism. It is crucial for bodybuilders to regularly check their eGFR levels, as low levels under 60 can indicate kidney damage or impaired kidney function, which can have a negative impact on performance. Maintaining a healthy eGFR level is essential for overall health and athletic performance. Consulting with a healthcare professional is recommended for interpreting eGFR results and taking the necessary steps to support kidney health. GGT Liver Test The GGT blood test looks for an enzyme, or protein, called gamma-glutamyl transpeptidase (GGT) in your blood. GGT is found in liver cells. This test helps your doctor look for damage to your liver or its ducts. It can also help tell the difference between liver and bone disease if your results from a different blood test called alkaline phosphatase are abnormal. Higher than-average test results could indicate liver damage from diseases such as hepatitis, cirrhosis, tumors, or pancreatic cancer. The good thing about GGT (unlike liver enzymes included in the CMP like AST and ALT) is that resistance exercise does not affect its value, so it is a more accurate way to detect liver disease in bodybuilders. Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Men with high testosterone cannot use the regular total testosterone test based on immunoassays since it has an upper limit of 1,500 ng/dL. The LC/MS testosterone test does not have an upper limit. Also, some labs offer calculated free testosterone instead of the equilibrium ultrafiltration-based one, which is more accurate for this critical variable. Free Testosterone (Equilibrium Ultrafiltration) Test The equilibrium ultrafiltration test is a precise method used to measure the amount of unbound testosterone in the bloodstream. Free testosterone plays a crucial role in muscle growth, strength, and overall performance for bodybuilders. Monitoring free testosterone levels can provide valuable insights into potential imbalances or deficiencies that may impact training, recovery, and hormone balance. By regularly testing free testosterone, bodybuilders can optimize their training and supplement plans to maximize their performance and health. This test, along with other essential lab tests, helps bodybuilders maintain optimal hormone levels and ensure their body is functioning at its best. Ultra-Sensitive Estradiol (E2) Test The commonly used estradiol test may overestimate estradiol. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This ultrasensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation. Furthermore, DHT analogs like oxandrolone may dramatically decrease estradiol, causing joint aches and other low estradiol issues. Note: 0.4 percent of total testosterone aromatizes to estradiol. This is the body's way of balancing testosterone's negative effect on lipids with estradiol's beneficial effect. If your total testosterone is high, so is your estradiol. Be very careful in assuming that an aromatase inhibitor is needed. For more information, click on the effect of high and low estradiol on men's health. How to predict estradiol for different testosterone doses. Prolactin Test Many bodybuilders worry about increased prolactin since it has been associated with erectile dysfunction. Regular monitoring of hormone levels is essential for bodybuilders, and the prolactin test plays a crucial role in this process. This test helps detect potential imbalances that can impact performance and overall health. Elevated prolactin levels may indicate issues such as reduced testosterone production or the presence of pituitary gland tumors. Therefore, it is vital for bodybuilders to undergo regular prolactin testing to optimize their performance and maintain their overall well-being. However, interpreting the results accurately requires consultation with healthcare professionals. By keeping prolactin levels in the optimal range, bodybuilders can enhance muscle growth, support recovery, and promote their overall physical and mental well-being. DHT Test This test measures the amount of dihydrotestosterone (DHT) in the blood. Low DHT has been associated with low libido, and high DHT has been linked to acne, hair loss, and benign prostatic inflammation in a minority of men. DHT test (LC/MS) measures dihydrotestosterone levels, a hormone linked to muscle growth and male characteristics. It helps bodybuilders evaluate hormonal balance for enhanced performance. Monitoring DHT levels provides insights into potential side effects or risks associated with supplements or steroid use. Regular testing tracks progress and informs decisions on training and supplementation. Discussing results with healthcare professionals creates personalized strategies for goals. IGF-1 Test Insulin-like Growth Factor 1, also known as IGF-1, is used as a biomarker for blood levels of human growth hormone. It is a hormone that the liver and other tissues produce that affects glucose metabolism and growth-promoting activities. Low IGF-1 may impede muscle growth. The IGF-1 test, performed using LC/MS, is a crucial tool for bodybuilders to assess their performance and overall health. This test measures the levels of insulin-like growth factor-1, a hormone that plays a vital role in muscle growth and repair. By analyzing IGF-1 levels, bodybuilders can determine whether they have optimal hormone levels for performance and recovery. Low levels of IGF-1 may indicate potential limitations in muscle growth or underlying health issues. Ferritin Test Ferritin is a protein that stores iron. Red blood cells need iron to form and carry oxygen around your body. Low levels of ferritin lead to anemia. TRT and anabolic steroids make the body make more red blood cells (erythrocytosis). This increased production decreases iron stores and ferritin. Testosterone has been shown to decrease ferritin. Men who use TRT and anabolic steroids and have high hematocrit (increased blood thickness due to TRT or anabolic steroids) frequently donate blood or undergo therapeutic phlebotomy to lower hematocrit. There is a loss of around 30 points of ferritin during every donation. Low ferritin can cause fatigue, restless leg syndrome, muscle aches, and other issues. How do these tests help optimize bodybuilding performance? Bloodwork tests play a crucial role in optimizing bodybuilding performance. They provide valuable insights into hormone levels, nutrient deficiencies, and overall health. By identifying imbalances or deficiencies, bodybuilders can make targeted adjustments to their diet and supplementation, enhancing muscle growth, recovery, and overall performance. Regular blood work helps track progress and make necessary adjustments to training and nutrition protocols. The role of these tests in muscle gain, fat loss, and quality of life Blood tests play a vital role in bodybuilding, specifically when it comes to muscle gain, fat loss, and overall quality of life. These tests provide valuable insights into hormone levels, such as testosterone and cortisol, which are crucial for optimal muscle growth and fat loss. By monitoring these blood markers, bodybuilders can optimize their recovery and prevent overtraining. Additionally, blood work can reveal any nutrient deficiencies that may be hindering progress in muscle gain or fat loss. Moreover, assessing liver and kidney function through blood tests ensures the overall health and longevity of bodybuilders. Regular blood work is essential for identifying potential health risks and allowing for timely intervention to maintain a high quality of life. How can bodybuilders prepare for these tests? To prepare for bodybuilding blood work, it's important for bodybuilders to stay hydrated, avoid strenuous exercise or heavy lifting 48 hours before the test, follow any fasting requirements given by the healthcare provider, and inform them about any supplements or medications being taken. Why is regular bodybuilding blood work essential? Regular monitoring of crucial parameters is essential for bodybuilders. It helps ensure optimal performance and overall health. By tracking hormone levels, liver function, and kidney function, bodybuilders can make informed decisions about their training, nutrition, and supplementation strategies. Regular blood work also provides a baseline for comparison and allows assessment of the effectiveness of lifestyle choices on health and performance. How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com To buy affordable bodybuilder blood work on DiscountedLabs.com, simply visit the website and create an account. Then, search for the specific bodybuilder blood work panel you need and add it to your cart. Proceed to checkout and apply any available discount codes before completing your purchase. Bodybuilder Panels Sold by DiscountedLabs.com Bodybuilder Blood Test Panel- Basic Bodybuilder Blood Test Panel- Beginner Bodybuilder Blood Test Panel- Comprehensive Conclusion Regular bodybuilding blood work is essential for maximizing performance and maintaining good health. It helps bodybuilders identify any imbalances or potential health risks caused by their training regimen and performance-enhancing agents. Understanding the importance of these tests and regularly monitoring key parameters such as testosterone levels, kidney function, liver enzymes, and lipid profiles can help bodybuilders optimize their muscle gain, fat loss, and overall quality of life. To ensure accurate results, it is important for bodybuilders to prepare for these tests by following specific guidelines. Regular monitoring of these parameters allows bodybuilders to make adjustments to their training and nutrition plans, minimizing potential risks and improving long-term outcomes. DiscountedLabs.com offers affordable bodybuilder blood work, making it easier for individuals to access these crucial tests. Take charge of your bodybuilding journey and prioritize your health and performance with regular blood work.        

Historically, when we think of sex hormones in men and women, we identify testosterone as the core regulator of orderly male growth and sexual function. In a similar fashion, we identify estrogens as central to regulating sexual and reproductive function, along with a host of non-reproductive functions in women. 17ß-Estradiol or E2, the principal form of estrogen, is also produced in significant quantities in males. Research over the last two decades has demonstrated that estrogens can play a pivotal role in regulating male sex drive, erectile function, spermatogenesis, and can also be responsible for body fat distribution, bone density, and overall morbidity and mortality. High estradiol, however, is known to cause breast tissue growth (gynecomastia) and water retention in men with low testosterone. Because of this dynamic, regulation of the balance of testosterone and estradiol in men is paramount. Although there is evidence to suggest that lower levels of estradiol (10-20 pg/ml) can increase bone loss, the impact of high levels of estrogen on male reproductive function and other morbid conditions is complex, and it is difficult to discern upper values for the optimal range where deleterious effects begin to occur. The impact of both estrogen deficiency and excess remains controversial. We present here a background of estradiol in men along with studies that highlight the importance of estrogen in male physiology.   Video: Increased Estradiol Improved Sex Drive in Men   Estradiol in Men: Background As early as the 1930s, it was known that the male testis was responsive to estrogen and that exposure to high doses of estrogens causes developmental abnormalities. It was also speculated that the source of estrogen in males was the conversion from testosterone, which at the time was still considered the main “male hormone.” It wasn’t until the 1950s that conversion of testosterone to estrogen became well-documented. In the following decades, it became well-established that males produced significant quantities of estrogens and males of multiple species had quantifiable amounts of circulating estradiol that was synthesized in reproductive and non-reproductive tissues. In females, ovaries are the main source of circulating estrogens and regulate many facets of the female reproductive system. In males, it has been shown that the testes only produce approximately 20% of circulating estrogens, with the remainder being produced in tissues such as adipose, brain, bone, and skin, which convert testosterone to estrogens through the aromatase cytochrome P450. The diffuse pattern of estrogen production in men meant that there was no simple means to produce an estrogen-deficient state in the male comparable to an ovariectomized female. Thus, the role of estradiol and estrogen signaling in the normal male remained elusive due to a shortage of clear endpoints for estrogen action, as well as a lack of a good experimental model to approach the problem. One significant advancement in the field came in the 1970s when it was demonstrated that the testes were the major source of estrogens in men. Biochemical analysis on aromatization of androgens to estrogens and protein labeling studies for localization of estrogen receptors (ER) and the conversion enzyme aromatase in the testis were utilized to further characterize the system. New developments in the ‘80s and ‘90s led to the hypothesis that estrogen and its α-receptor were “essential” for normal fertility. Because of this, the interest in the implications of estrogen signaling in the male reproductive system increased toward the end of the century. Work over the last two decades in genetically modified mouse models, and the discovery of natural mutations in men helped to make major advances in the investigation of estrogen physiology in men. Studies further revealed that estrogens are critical for normal development and function of male reproductive and nonreproductive organs.   Sex Steroids and the Male Libido As mentioned earlier, testosterone has long been identified as the dominant sex hormone in men, and we now know that estradiol, previously thought to be only a female hormone, also plays a critical role in modulating libido, erectile function, and spermatogenesis. The extent of this role, however, is unclear and remains the subject of debate. There is an abundance of estrogen receptors, as well as aromatase in organs important to sexual function such as the brain, penis, and testis. Estradiol, therefore, can affect libido at multiple stages. Studies have indicated that decreased testosterone is associated with low libido in males. In these men, administration of exogenous estradiol can improve libido. It is known that higher testosterone levels in men can prompt higher estradiol levels through conversion of androgens like testosterone to estradiol. In male hypogonadism, a condition in which the body does not produce enough testosterone, testosterone replacement (or supplementation) therapy can improve quality of life. Testosterone therapy is prescribed for millions of men and the numbers are increasing yearly. Currently, testosterone therapy is more often used in patients with non-specific symptoms, such as sexual function and fatigue, when lab levels of testosterone fall below a certain criterion (2 standard deviations below the mean value for health young adults). Although the measure is helpful, it fails to address the physiological changes at certain testosterone levels or potential role of the associated decline in estrogens that may occur in androgen deficiency. Effect of Testosterone and Estradiol on Men's Libido: In an innovative study to address these concerns, one group recruited healthy males to determine the point at which undesirable changes begin to occur with testosterone deficiency, estrogen deficiency or both and whether these changes were androgen-dependent, estrogen-dependent or a combination of the two.(Finkelstein et al. 2013) 2 groups of males (20 to 50 years of age) with normal testosterone levels were given goserelin acetate (to suppress endogenous testosterone and estradiol) and randomly assigned them to receive varying amounts of 1% testosterone gel (0g, 1.25g, 2.5g, 5g, or 10g) for 16 weeks. One group also received an aromatase inhibitor to suppress the conversion of testosterone to estradiol. Over the 16-week period, changes in body fat percentage, lean mass, subcutaneous- and intraabdominal-fat areas, thigh-muscle area and strength, and sexual function were assessed. The findings of this study indicate that when estradiol production was intact, fat accumulation began with mild testosterone deficiency (about 300 to 350 ng per deciliter). Lean mass, thigh-muscle area, and muscle strength, however, were maintained until testosterone levels dropped below 200 ng per deciliter. Sexual desire and erectile function exhibited different patterns in response to changes in serum testosterone reduction. While changes in lean mass, thigh-muscle area, and leg-press strength were associated with variations in testosterone levels, changes in fat measures were associated with changes in estradiol levels. Also, both androgens and estrogens were responsible for the maintenance of libido and erectile function.   Low Estradiol and Fat Gain: Surprising Results This study provides important information regarding the interpretation of testosterone levels in young and middle-aged men. The authors indicate that the increases in intraabdominal fat with aromatase inhibition can foreshadow an increase in cardiovascular disease observed with long-term estrogen deficiency. Lastly, since lean mass, thigh-muscle area, and erectile function were reduced at a dose of testosterone that prompted a mean serum level of approximately 200 ng per deciliter (1.25g per day).   High Estrogen in Men: Studies In the past, there has been some concern with possible side effects of elevated estrogen levels (hyperestrogenism), such as fatigue, gynecomastia, diminished libido, and erectile dysfunction. A large retrospective study conducted at 35 Low T Centers sought to understand if there were predictive factors of patients who were more likely to develop high estradiol levels after testosterone replacement therapy. (Tan, Cook, and Reilly 2015) As part of the study, the researchers also incorporated the use of aromatase inhibitor (AI) such as anastrozole (Arimidex) and selective estrogen receptor modulators (SERM) such as tamoxifen (Nolvadex) to alleviate symptoms of hyperestrogenism. The trend in estradiol levels in the 4 age groups studied (<25, 25 to 44, 45 to 65, and >65 years) was analyzed. Estradiol was lowest in the <25 years age-group with a rise in the 2 middle age groups the gradually tapered in the oldest age group (>65 years). Much of the use of aromatase inhibitors was in the 2 middle age groups, resembling the prevalence of hyperestrogenism. Interestingly, it was determined that patients with lower estradiol (<42.6 pg/ml) had complaints of low libido. The authors also make note that despite the use of AI and SERM in 30% of the treatment population, side effects occurred in <1%. One additional study worth mentioning sought to determine the associations between serum testosterone, estradiol, and libido in men undergoing testosterone supplementation therapy for symptomatic hypogonadism (total testosterone <300 ng/dl and 3 or more symptoms on the Androgen Decline in Aging Male questionnaire [ADAM]). (Ramasamy et al. 2014) As part of the ADAM questionnaire, all men were asked to rate their libido on a 5-point scale. Men were categorized into low (<300 ng/dl) or high (>300 ng/dl) testosterone and low (0.5-5.0 ng/dl) and high (>5.0 ng/dl) estradiol. Serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), serum testosterone, and sex hormone-binding globulin (SHBG) were analyzed to evaluate factors predicting libido. Men with high serum testosterone and estradiol levels reported greater libido. In total, 60.4% of men with both high serum testosterone and estradiol levels reported a very good to excellent levels of libido on their questionnaire. When analyzing the combined data, only estradiol at serum levels >5 ng/dl was associated with a greater libido. The authors indicate several limitations of the study and despite the lack of proper controls, a small sample size, and absence of score comparison before and after initiation of therapy, the study emphasizes the importance of estradiol in men on testosterone. Another recent study showed that change in estradiol level was the best predictor not only of the change in bone mineral density (BMD) and sexual desire.    Conclusions: In a review of the clinical implications of estrogens for sexual function and testosterone replacement therapy, one group notes that estrogens may contribute to the persistence of sexually stimulated erectile function when serum testosterone is severely depressed. Naturally occurring elevations in estradiol do not appear to be harmful, and the incidence of symptoms of excess estrogens are rare. They also add that the use of aromatase inhibitors is not recommended for long-term use and recommend against the use of aromatase inhibitors in men that experience positive effects from testosterone therapy despite elevated estradiol concentrations. When used, an aromatase inhibitor should be titrated so that estradiol levels remain above 40 pmol/L to preserve bone health. It is important to mention that levels of circulating sex hormones are highly regulated via feedback loop of the hypothalamic-pituitary-gonadal (HPG) axis and on a tissue level with aromatase activity. As levels change, the body compensates. Caution should be taken when testosterone is used pharmacologically. It is difficult to compare the response from patient to patient because of many contributing factors and levels of testosterone alone may not give a clear picture of an individual’s disposition.   References Cooke PS, Nanjappa MK, Ko C, Prins GS, Hess RA. Estrogens in Male Physiology. Physiol Rev. 2017 Jul 1;97(3):995-1043. Finkelstein JS, Yu EW, Burnett-Bowie SA. Gonadal steroids and body composition, strength, and sexual function in men. N Engl J Med. 2013 Dec 19;369(25):2457. Tan RS, Cook KR, Reilly WG. High estrogen in men after injectable testosterone therapy: the low T experience. Am J Mens Health. 2015 May;9(3):229-34. Ramasamy R, Scovell JM, Kovac JR, Lipshultz LI. Elevated serum estradiol is associated with higher libido in men on testosterone supplementation therapy. Eur Urol. 2014 Jun;65(6):1224-5. Vermeulen A, Kaufman JM, Goemaere S, van Pottelberg I. Estradiol in elderly men. Aging Male. 2002 Jun;5(2):98-102. Kacker R, Traish AM, Morgentaler A. Estrogens in men: clinical implications for sexual function and the treatment of testosterone deficiency. J Sex Med. 2012 Jun;9(6):1681-96. Hess RA. Estrogen in the adult male reproductive tract: a review. Reprod Biol Endocrinol. 2003. Rochira V, Granata AR, Madeo B, Zirilli L, Rossi G, Carani C. Estrogens in males: what have we learned in the last 10 years? Asian J Androl. 2005 Mar;7(1):3-20. Schulster M, Bernie AM, Ramasamy R. The role of estradiol in male reproductive function. Asian J Androl. 2016 May-Jun;18(3):435-40. Blakemore J, Naftolin F. Aromatase: Contributions to Physiology and Disease in Women and Men. Physiology (Bethesda). 2016 Jul;31(4):258-69.

Searching for " TRT Doctor Near Me "? If you have signs of low testosterone, like low sex drive, erectile dysfunction, less motivation, or mood swings, you should find a good TRT doctor near you. A qualified TRT doctor can treat these issues with testosterone replacement therapy. This treatment can help boost your sex drive and sexual function. It can also raise your energy levels and improve your mood and thinking. With a TRT doctor by your side, you can feel like yourself again and enjoy life better. Plus, having low testosterone levels might put you at a higher risk for heart disease. That’s why it’s important to see a trusted TRT doctor. Understanding Testosterone Replacement Therapy (TRT) Testosterone Replacement Therapy (TRT) can change lives for men with low testosterone levels. This treatment helps those who want a better life. TRT means using testosterone medications to bring testosterone levels back to a normal state in the body. It can boost mood and energy levels, improve libido, and increase muscle mass. It may also reduce body fat and irritability. However, you should talk to a qualified TRT doctor before starting. The doctor will check your testosterone levels and explain the risks and benefits of this therapy. They will help you decide if it is right for you. What is Low Testosterone or Hypogonadism? Low testosterone, also known as hypogonadism, affects many men as they get older. Testosterone levels are highest during early adulthood. After 30, these levels usually drop by about 1 to 2 percent each year. This slow decline can cause several health problems. A low testosterone level can result in symptoms that can greatly affect a man's life. It is important to understand what low testosterone means. This can help in knowing when to seek medical checks and possible treatment. As testosterone levels drop, men might feel several symptoms. These include tiredness, lower libido, and mood swings. These changes can link to a condition called hypogonadism. This condition can impact sexual health and may need medical help to balance hormones again. If you think you have low testosterone, it's important to talk to a qualified doctor. They can provide the right diagnosis and treatment options for you. Common Symptoms of Low-T Recognizing the signs of low testosterone is important for quick diagnosis and treatment. Many men with low testosterone, or Low-T, face several concerning symptoms that can impact their everyday life. Here are some common symptoms to watch for to get more info: Reduced sex drive: A drop in libido can cause problems in relationships and lower overall happiness. Erectile dysfunction: Low testosterone levels can make it hard to get or keep an erection, which affects sexual performance. Loss of muscle mass: Many guys see a reduction in strength and muscle tone, making it tough to stay fit. Fatigue: Ongoing tiredness and low energy are common issues linked to low testosterone levels. It is important to know that these symptoms can feel different from person to person. Many things, like age, lifestyle, and health, can change how severe they are. If you notice any of these symptoms, especially those related to prostate health, it's a good idea to see a doctor. A healthcare professional can do tests to check your testosterone levels. They can also talk about the right treatment options for you. Understanding and dealing with low testosterone can really help improve your health and well-being. Your Ultimate Guide to Finding a TRT Doctor Near Me When we start any health treatment, we mainly want to find the best options. This is true for men who feel symptoms of low testosterone. Sadly, many men find it very hard to find a doctor who will treat testosterone deficiency properly. More doctors around the world are learning about testosterone and how to treat it. Still, some doctors think treating low testosterone is unnecessary. They believe testosterone levels drop naturally as we age, so we should just accept it. This view is strange because doctors usually don’t think this way about other health issues. For many years, testosterone and related supplements have been viewed differently in medicine for several reasons we won't discuss now. Right now, we just want to understand how to find the right testosterone replacement therapy (TRT) doctor. A good doctor can help meet your needs and boost your quality of life as you age. Plus, you can still enjoy a satisfying sexual life. When you search for "testosterone doctor near me" on Google, you will see many clinics advertised. But how do you find the best one for you? It might surprise you that there are no reliable doctor directories for testosterone and hormone treatments, not just in the United States but worldwide. Thankfully, a new directory helps men and women find hormone clinics nearby. Just go to the site and click on "Search." If there are clinics near you, they will email you with details about their services, including hormone replacement therapy. You can also tailor your search by health issues, TRT, and other related products that interest you. To find a TRT doctor near you, click on the image below. Main Questions to Ask a TRT Doctor Once you find a doctor who treats low testosterone with TRT therapy, this is just the first step. The next step is more important and can be harder. You need to find a doctor who prescribes TRT the right way. There are many ways to treat low testosterone, just like the saying goes about skinning a cat. But, some of these ways can be less effective and could even cause problems or worse outcomes. First, learn as much as you can by reading a testosterone book such as "Testosterone: A Man's Guide." Also, check posts on the top TRT forum, ExcelMale.com. This knowledge will help you become an informed patient. You will feel more comfortable asking questions to a TRT doctor or clinic. Once you find a doctor who treats TRT, there are several questions to ask. Some doctors may not want to answer these questions. They might feel you are questioning their skills and prefer you to stay quiet and accept what they say without asking. It's important to remember that while you should respect your doctor, they are here to serve you. You pay for their services. If a doctor is not willing to answer basic questions or have a discussion, it may be time to look for another one. If your TRT doctor is open to talking before taking the next steps, here is a helpful list of questions for you to ask: 1. How long have they been treating patients with low testosterone, and how many are they currently treating? The answer to these two questions does not have to be a deal-breaker. This is true if a person hasn't been doing this for long or if they haven't treated many people. What really matters is that they know the right way to treat. Still, if the numbers are low, this might be a sign to watch. Anyway, let’s keep going with our questions. 2. What type of TRT treatment options do you prescribe—injectables, creams, or other options? Self-given injectable testosterone is often seen as one of the best and most affordable ways to handle low testosterone. However, some men might feel uneasy about using needles. For them, testosterone gels or creams could help with weight loss. Other options for testosterone replacement therapy (TRT) include pellets, nasal gel, oral forms, long-lasting injections, and more. 3. Do they accept insurance or cash pay only? If they take insurance, that's great. You should use it with good treatment. But if you can only get the best treatment by paying cash, you may need to choose that option if your budget lets you. 4. Do they prescribe HCG along with testosterone, or have it available as an option for treating testicular atrophy or helping to preserve fertility? Many men like the extra benefits that HCG can provide for their testosterone replacement therapy (TRT). Younger patients especially feel good knowing that they can still conceive well with HCG. Sadly, many doctors, even those who know more about testosterone than most, do not get the advantages of using HCG with TRT. This can be a warning sign, and it might be a good idea to find a new doctor. 5. Do they prescribe other products or ED medications? When a person is on testosterone replacement therapy, simply boosting testosterone levels is not enough. We need to think about all the hormones in our body. One important hormone to watch is estradiol. A high level of estradiol compared to testosterone can cause unwanted side effects. These may include gynecomastia, water retention, and erectile issues. For instance, if a man has too much estrogen, he may struggle to get a firm erection. On the other hand, if he has too little estrogen, keeping an erection can be hard. Testosterone is also key for strong bones and muscle mass. Contrary to what people read online, most men won't need an aromatase inhibitor in the long run. However, having the option to get one when necessary is important. Moreover, when a man has low testosterone and sees symptoms like gynecomastia or growing breasts, gaining weight can lead to further health issues, such as high cholesterol and diabetes. 6. Blood testing: How often is your doctor going to run lab tests? What are they going to check on the lab report? After the first test, you should have lab tests every 6 to 8 weeks. This should continue until your levels are stable and in a good range. It may take 3 to 6 months to achieve this. A “good range” means looking at both your numbers and how you feel. Be sure to ask your doctor if they will check both total and free testosterone in your tests. Just checking total testosterone is not enough. Also, ask your doctor if they'll check estradiol levels with the sensitive estradiol test, not the regular estrogen test. Remember, the sensitive estradiol test may not be available in all countries. A regular test often shows higher estradiol levels due to other factors affecting the results. Many people still discuss if it’s necessary to manage or treat high estrogen levels in men who are on TRT. Your doctor should check your hemoglobin and red blood cell levels. They can request a therapeutic phlebotomy at the nearest blood center. This will allow you to donate blood. Some doctors may check your thyroid function. This is because low thyroid (hypothyroidism) can feel similar to low testosterone. So, make sure to mention it! Remember, if your doctor is open and caring, they might let you order your own lab tests. This way, you can get the exact tests you need through sites like DiscountedLabs.com. 7. Do they offer prescriptions for therapeutic phlebotomy for high hematocrit? Your blood might get a bit thick with TRT. This is not a big problem if we fix it, and it's simple to correct. You can go to a blood center and donate blood. If your doctor orders the right tests, you can keep an eye on this issue. If needed, you can solve it by donating blood. Remember that giving blood often can lower your iron and ferritin levels. This can lead to feeling very tired. Do not donate blood more than once every 2.5 months. 8. Do they offer other treatment options, such as erectile dysfunction medications, high blood pressure medications, or other wellness options? You might need these things or you might not; we will see as time goes by. However, it's always a good idea to have them available just in case you need them. 9. One of our most important questions we will need to ask our doctor is: do they allow self-injecting at home? If the testosterone injection plan is done right, we will discuss it in the next question. There is nothing more frustrating than visiting the doctor every week or even several times a week. Your doctor should let you inject the medicine at home. If they do not, it's time to find a new doctor. 10. Injection protocols: Ask your doctor if they are prescribing testosterone cypionate or testosterone enanthate and what their typical injection protocols look like. If your doctor gives you injections every two weeks or less, ask if you can take them once a week or even twice a week. Some men feel the effects of testosterone replacement therapy (TRT) wearing off around days 12 to 14 with just every two-week injections. Also, if your doctor does not let you use an insulin syringe to inject under the skin instead of older methods, ask why. New information shows that subcutaneous injections work just as well as deep intramuscular ones and are less painful. 11. Does your TRT doctor work with compounding pharmacies or allow you to work with the pharmacy of your choice? If your insurance covers your TRT, be sure to compare pharmacies. Look for one that offers the lowest copay. If you are paying in cash, check compounding pharmacies. They often have lower prices for injectable and transdermal (gel or cream) testosterone products. A good doctor will give you a prescription for a generic drug. This helps you go to a compounding pharmacy. There, you can get the same testosterone for a much lower price than with a big-brand pharmacy. A good doctor likely knows someone at a compounding pharmacy, which makes this process easier. Plus, you will usually find that the service at a compounding pharmacy is better than at other pharmacies you know. 12. Ask your doctor how many times they will require you to come to the office. If it’s more than twice a year, this doctor probably isn’t for you. It is important for you to know that the doctor will let you see your lab results. They should also have an open talk with you about your health. If you feel that this will not happen, you should consider finding another doctor. 13. What’s all this going to cost me? How much will the doctor’s visit cost, including any follow-up visits? How much will blood work cost, including follow-up labs? Finally, how much can I expect to pay monthly for medications, and are there any other fees I need to be aware of that may exist? Preparing for your first TRT doctor visit is important. It helps you feel confident in your decision. It also helps you understand what to expect and how much it will cost. Visit ExcelMale.com for information about TRT treatment options and other men's health choices. Common Men’s Tests: Bodybuilder Tests Cancer Tests Erectile Dysfunction Tests Fatigue Tests Hormone Clinic Referrals Hormone Testing Hormone Tests for Men Male Hormone Tests Men's Health Tests Testosterone Tests Thyroid Lab Tests TRT Side Effects Tests TRT Tests These tests can help you understand your health better. There are options for issues like erectile dysfunction. You can also look into testosterone tests. They can provide useful information for men's health.   Common Questions   How Can I Get Prescribed TRT Near Me? If you think you might have low testosterone levels and want to look into TRT as a treatment, you should talk to a healthcare professional. A primary care doctor or an endocrinologist at a men's health clinic can help you. They will check your symptoms and look at your medical history. They may also do blood tests to check your hormone levels. If these tests show low testosterone levels and you qualify for TRT, your provider can explain the benefits and risks of this therapy. They will also help you get a prescription if needed. It is very important to work with a qualified healthcare professional. This will help you get the right diagnosis. They will also monitor and manage any hormonal imbalances properly. What is the cost of TRT? Every clinic charges different prices for lab work, medications, and doctor visits. A self-pay clinic can cost between $100 and $250 each month. This depends on the TRT and other medications that are given. Does insurance typically cover TRT? TRT, or Testosterone Replacement Therapy, may or may not be paid for by insurance. This depends on your insurance plan and your testosterone level. Some insurance plans can cover TRT, especially if it is needed for low testosterone levels. However, the coverage can be very different from one plan to another. So, it is important to ask your insurance provider if TRT is included in your plan. You may also need to meet some requirements or get approval from your insurance company before you start TRT. It is smart to talk with your healthcare provider and your insurance company to understand the details of your coverage for TRT. What type of doctor should I see for TRT? If you are thinking about testosterone replacement therapy (TRT), you should talk to a healthcare expert. Look for someone who is specialized in hormone therapy, urology, or endocrinology. These doctors know how to check your symptoms and run the right tests. They can create a treatment plan just for you. They will also keep track of your hormone levels and change your treatment if needed. This helps you get the best results and reduce side effects. It’s very important to have a skilled healthcare provider to help you during the process and give you support along the way. How do I find a reputable testosterone doctor near me? Finding a good TRT doctor nearby is an important step for fixing hormone issues or worries. Here are some tips to help you find a trusted TRT doctor: Research online: Begin by searching online for doctors or clinics that focus on hormone therapy or TRT near you. Look for reviews and testimonials. Check their credentials or certifications to see their skills in this area. Ask for referrals: Talk to friends, family, or coworkers. They might have gone through TRT or know someone who has. They can guide you to a good doctor or clinic from their own experiences. Talk to your main doctor: Your main doctor can give you advice or connect you with a specialist who focuses on hormone therapy or TRT based on your personal preferences. Look at professional directories. You can find them at places like the American Academy of Anti-Aging Medicine (A4M) or the American Urological Association (AUA). These directories can help you find doctors who focus on hormone therapy or TRT. Once you find some doctors you might like, the next step is to set up meetings with them. During these consultations, ask questions about their experience and how they treat patients. It's also good to learn about possible side effects or risks of TRT. Don't forget to check their credentials and licenses before you start any treatment. What questions should I ask before scheduling an appointment with a testosterone doctor near me? When you want to schedule an appointment with a possible TRT doctor, it’s good to ask some important questions. This way, you can make sure they are the right choice for you. Here are some questions you might think about asking: What experience and qualifications do you have for prescribing TRT? What tests will you do to see if I can get TRT? Will my treatment plan be made just for my needs and goals? What are the possible risks or side effects of TRT, and how will you watch for and manage them? How often will I need to come back for follow-up appointments, and what will happen during those visits? Are there any lifestyle changes or extra therapies that I should think about with TRT? Finding the right urologists is very important for your health. Don't hold back on asking these questions or any others that pop into your head during your first visit. It’s key to feel good and sure about the care you get. What are some common treatments that testosterone doctors recommend, and what are the potential side effects? TRT doctors might give you different types of testosterone. You could get injections, gels, patches, or pellets. The way you will be treated will depend on what you need and what you prefer. Some possible side effects of TRT are acne, water retention, more red blood cells, less sperm production, testicle shrinking, mood swings, and sleep apnea. However, not everyone will have these side effects. They can be different for each person. If you are thinking about TRT or have questions about treatments or side effects, it is a good idea to talk to a qualified healthcare professional. He or she specializes in hormone therapy. They can give you advice that is specific to your situation and medical history.