Bodybuilder lab tests

Is 2ml of Testosterone a Week Enough to Build Muscle? Study Results Testosterone is a hormone that plays many roles in the body, like building muscle, increasing strength, sexual health, and overall well-being. People wonder how much testosterone is needed to achieve these benefits, especially when considering testosterone replacement therapy (TRT) for muscle growth. Those with low testosterone might be considering TRT to feel better. But figuring out the right testosterone dose to use is tricky because it depends on your age, health, diet, exercise program, and how your body reacts to the treatment. In this article we will be looking at a study by Dr. Bhasin and his colleagues in 2001 published in the American Journal of Physiology and Endocrinology Metabolism. Their study was to see how different amounts of testosterone affect young men and what’s the best dose for different results. By going through what they found out we can learn a lot about what’s the right amount of testosterone for getting stronger or building muscle. Watch video here: What is the Optimal Testosterone Dose? Testosterone and Muscle Growth Testosterone is a hormone that plays a big role in muscle growth and development. Produced mainly in the testicles in men, testosterone is responsible for the development of male characteristics, including muscle mass and strength. As men age, their testosterone levels decline naturally, which can lead to a decrease in muscle mass and strength. This decline can affect overall health and well-being, so it’s important to understand the connection between testosterone and muscle growth. For those who want to build muscle, maintaining optimal testosterone levels is crucial. Testosterone stimulates protein synthesis, which is the process by which the body repairs and builds muscle tissues. Higher testosterone levels can increase muscle mass, strength, and overall health. By understanding how testosterone affects muscle growth, you can make informed decisions about your fitness and health goals. Testosterone Replacement Therapy (TRT) for Muscle Growth Testosterone Replacement Therapy (TRT) is a treatment for those with low testosterone. TRT involves injecting, gelling, or patching testosterone to restore normal testosterone levels. This is especially good for those experiencing symptoms of low testosterone such as decreased muscle mass, fatigue, and decreased libido. TRT can increase muscle mass and strength, bone density, and overall health. By restoring testosterone levels, TRT supports the body’s natural ability to build muscle and perform physically. But please note that TRT should only be done under the guidance of a doctor. While TRT can be beneficial, it also has side effects and risks, like increased red blood cell production and changes in cholesterol levels. So medical supervision is necessary to ensure safe and effective treatment. The Study In the study, about 65 young men around 25 years old and in good shape were studied. The study also included 1 ml of testosterone as part of the dosage variations. First they stopped their bodies from making testosterone naturally by giving them a drug that blocks testosterone. Then for 20 weeks they gave these men shots of a type of testosterone called cypionate once a week. The dose varied from 25 milligrams to 600 milligrams a week. By doing this, they could see how different doses affect different things. Testosterone Dose and Hormone Levels The study found a correlation between the dose of testosterone and the levels of different hormones in the body. They looked at total testosterone, free testosterone, LH (luteinizing hormone), SHBG (sex hormone-binding globulin), and IGF-1 (insulin-like growth factor 1). Here’s what they found out: As the dose of testosterone increased, so did the total testosterone levels in the body. At the beginning, the subjects had testosterone levels of 500-600 ng/dL. By week 16, those who got higher doses (300-600 mg/week) had levels of 1300-2300 ng/dL. Even with a smaller dose of 125 mg/week, the subjects had levels near what they started with. So taking around 100-125 mg/week might be enough for young men to get their testosterone back to normal. Free testosterone: Just like total testosterone, as more was given, free testosterone increased. So more dosage means more free testosterone is available in your system. LH and SHBG: The more testosterone you take, the lower these levels go. As people increase their dose of testosterone, they see a drop in LH and also in SHBG. So taking more testosterone can slow down LH production and decrease SHBG. So more free testosterone is available for your body to use. Testosterone dosage for muscle growth and body composition The study looked into how different doses of testosterone affect muscle building, muscle size, and body composition. They used various methods to measure lean muscle mass (fat-free mass) and body fat. Here’s what they found out: For fat-free mass, the study found that 100-125 mg of testosterone per week helped people gain muscle without fat. Those who took these doses had less body fat and more muscle. Even more (300-600 mg/week) gave better results in gaining muscle without fat. But the smallest doses (25-50 mg/week) didn’t do much; sometimes they even added fat. For body fat, it seems that higher doses help reduce it. Those who got 100-125 mg per week lost body fat. Those who got very low doses (25-50 mg/week) didn’t lose weight or might have added body fat. So high levels of this hormone can make you leaner by cutting down fatty tissues while increasing muscle growth. Factors to Consider in Testosterone Dosage Determining the right testosterone dosage for TRT involves considering age, health status, and individual goals. Age is a big factor, as older men may need different dosages than younger men due to natural hormonal decline. Men with underlying health conditions such as cardiovascular disease or metabolic disorder may need customized dosages to ensure safety and effectiveness. Individual goals also matter in determining testosterone dosage. For example, someone looking to improve overall health may need a different dosage than someone looking to gain massive muscle and bodybuilding. Personalized treatment plans are necessary to address these individual needs and goals. Working with a doctor is key to determining the right dosage. Regular blood tests and monitoring can help adjust the dosage as needed to keep testosterone levels within normal range. By considering these factors and working with a medical professional, you can get the best out of your TRT. Testosterone Dose and Sexual Function and Libido The study also looked into how different doses of testosterone affect sexual function and desire. To find out they asked participants to fill out questionnaires about their sex life and how much they wanted sex. Here’s what they found out: For sexual activity, the study didn’t show much change in how often people were sexually active when they took more testosterone. The frequency of sexual encounters remained the same across all doses. Note that there were not many participants in this study, so this might have affected the results. For libido, it was found that 300-600 mg/week of testosterone gave a slight increase in desire. But 25-125 mg/week didn’t make much of a difference in libido. So higher doses used by bodybuilders might be more effective in increasing sexual desire. No Change in Cognitive Function In the study they also looked into how well people can think and remember. But even with different doses of testosterone, there was no big change in brain function. Note that this study was done on young guys. To know if testosterone affects thinking and memory in older men more studies need to be done. Testosterone Dose and Strength and Power In the study they tested the strength and power of participants’ legs by having them do leg press for 20 weeks. What they found out was interesting—the amount of testosterone given to the participants made a difference in how much stronger or more powerful their legs became. Those who got 300-600 mg/week had a significant increase in strength and power of their legs. So taking higher doses of testosterone can make you stronger and more powerful even if you don’t work out. Hemoglobin, Hematocrit and Cholesterol Levels Giving testosterone changes blood counts and fat levels in the body. The results match what we already know: Hemoglobin: As testosterone dose increased, so did hemoglobin levels. So as more testosterone is given more hemoglobin goes up. This means treatment with testosterone can affect erythropoiesis, which is how our body makes red blood cells. Just like hemoglobin, when testosterone doses go up, so does hematocrit. Hematocrit is all about how much space red blood cells take up in our blood. The study didn’t specify what’s the ideal level of hematocrit is, but note that too much can be bad for your heart health. Lipid Profile: The administration of testosterone caused a fluctuation in the levels of HDL cholesterol, the beneficial type. When you have more testosterone in your system, your HDL cholesterol tends to decrease. So it’s really important to monitor lipid profiles if you’re on testosterone therapy. Conclusion In 2001 Dr. Bhasin and his team did a study that looked into how different doses of testosterone affect several factors. Although the study was done on young men and had a small number of participants, it still gives us valuable information on how testosterone levels relate to muscle size, sexual health, brain function, physical strength, and blood-related measures. According to the study, 100-125 mg/week may be enough for young men to get their testosterone levels back to normal. For bodybuilding, 300-600 mg/week seems to increase muscle size, strength, and sex drive. But we have to remember that people react differently to each other. So any treatment with testosterone should be customized for each person’s needs and monitored by a healthcare professional who knows what he’s doing. Note that the study was done more than 20 years ago. Since then there might be new findings. If you’re thinking of testosterone therapy, talk to medical experts. They can assess your situation and give you personalized advice. The study provides valuable insights into the functioning of testosterone dosing, highlighting the need for further investigation. By doing more research, we can make the most of testosterone therapy and minimize the downsides. Get a budget-friendly testosterone test without seeing a doctor. Buy a testosterone test from DiscountedLabs.com and find out your testosterone blood level and adjust your TRT dose. FAQs Is 2 ml of testosterone a week enough to build muscle? The study above showed that 125 mg/week of injectable testosterone was enough to increase muscle. 2 ml of testosterone is 400 mg/week which will increase muscle but may cause high hematocrit, water retention, and blood pressure. How much test cypionate a week for bodybuilding? The study above showed that 125 mg/week of test cypionate is enough to increase muscle in bodybuilding without TRT side effects. References: In a study titled "Age trends in the level of serum testosterone and other hormones in middle-aged men: longitudinal results from the Massachusetts male aging study", researchers looked at how hormone levels, including testosterone, change as men get older. The article "Testosterone Replacement in Older Men: A Clinical Perspective" discusses the benefits and considerations of giving older men testosterone to improve their health. According to research found on Harvard's website, scientists have figured out what dose of testosterone works best for women. Another study called "Effects of Testosterone Treatment on Body Fat and Lean Mass in Obese Men on a Hypocaloric Diet: A Randomized Controlled Trial" explores how taking testosterone can help obese men lose fat but keep muscle while eating fewer calories.

Your hormones control everything from energy and strength to recovery and muscle-building. Regular testing can identify imbalances that hold you back and help fine-tune your training, diet, and recovery. Here’s a quick summary of the 8 key hormone tests every athlete and bodybuilder should know about: Testosterone: Measures muscle growth and recovery potential. Cortisol: Tracks stress and recovery balance. Growth Hormone (GH): Supports muscle repair and fat metabolism. Thyroid Function: Regulates energy and metabolism. IGF-1: Reflects growth hormone activity for muscle building. Estradiol: Affects recovery, bone health, and fat distribution. DHEA: Precursor to testosterone and estrogen, key for hormonal balance. LH & FSH: Monitors reproductive health and testosterone production. Why it matters: Hormonal imbalances can lead to fatigue, poor recovery, and reduced performance. Testing provides actionable data to optimize training and avoid overtraining. Pro Tip: Start with a testosterone-to-cortisol ratio or thyroid panel if you're noticing fatigue, slow recovery, or muscle loss. Dive into the full article for details on each test and how to use them to improve your results. Fitness Improvement Requires Stress & Cortisol 1. Testosterone Levels Testing testosterone levels is crucial for athletes, as it directly affects muscle growth, recovery, and overall performance. Understanding Testosterone Testing Blood tests are used to measure two key types of testosterone: total testosterone (which includes both free and protein-bound forms) and free testosterone (the active form). For the most accurate results, it's recommended to test between 7 a.m. and 10 a.m., when levels are naturally highest [3]. Services like DiscountedLabs.com offer hormone panels at over 2,200 locations across the U.S., delivering confidential results in just 2–7 business days. This detailed measurement helps assess performance potential and identify areas for improvement. Normal Testosterone Ranges for Athletes Gender Normal Range (ng/dL) Men 300–1,000 Women 15–70 Dr. Paul Gittens, a board-certified urologist and founder of the Rockwell Centers for Sexual Medicine and Wellness, emphasizes: "It's not all about numbers. It's about how your numbers reflect with your symptoms." [2] How Testosterone Affects Athletic Performance Maintaining balanced testosterone levels is essential for any athlete aiming to maximize strength and recovery. Testosterone supports several key functions, including: Promoting muscle protein synthesis Maintaining bone density Speeding up post-workout recovery Regulating fat distribution It's worth noting that testosterone levels naturally decline by about 1.6% per year, which can influence performance over time. Signs of Low Testosterone Be alert to these potential warning signs of low testosterone: Loss of muscle mass despite consistent training Longer recovery periods after workouts Reduced strength gains Unusual fatigue during exercise Lack of motivation to train Dr. Justin Dubin, a urologist and men's health expert at Memorial Healthcare System, points out: "Just because your testosterone is very, very high doesn't mean you have a better libido or anything. Everyone's body is different." [2] 2. Cortisol Measurement Cortisol, often referred to as the "stress hormone", can directly impact recovery and performance when levels remain elevated for too long. For athletes and bodybuilders, keeping cortisol in check is key to improving training outcomes. This hormone plays a role in regulating metabolism, immune response, and inflammation [7]. Testing Methods and Timing Cortisol levels can be assessed using three primary methods: Test Type Collection Time Normal Range (8 a.m.) Blood Test Morning + 4 p.m. 5-25 mcg/dL Saliva Test Before bedtime Varies by lab 24-hour Urine Full day collection Lab-specific Impact on Athletic Performance When exercise intensity exceeds 60% of VO2 max, cortisol levels naturally rise [6]. While short-term spikes are part of the body's normal response, consistently high levels can lead to: Poor muscle recovery Weakened immune function Loss of bone density Trouble sleeping Increased fat storage Professor Chris McLellan highlights the importance of monitoring cortisol: "Cortisol testing provides coaches, trainers and health & fitness professionals with increased capacity in conjunction with existing performance monitoring methods to establish preparedness for training and competition and optimize recovery. With cortisol, what gets measured, gets managed." [4] Understanding these effects is just the first step. The next challenge is learning how to control elevated cortisol levels. Managing Cortisol Levels Overtraining can cause a surge in cortisol that slows recovery and breaks down muscle tissue [8]. To keep cortisol levels balanced: Post-workout nutrition: After exercise, drink a carb-to-protein mix in a 3:1–4:1 ratio to help regulate cortisol [5]. Training structure: Build workout routines that include proper rest periods, especially for endurance-focused athletes [5]. Recovery strategies: Incorporate stress management techniques and prioritize high-quality sleep [4]. 3. Growth Hormone Testing Growth hormone (GH) testing plays an important role for athletes and bodybuilders aiming to improve performance and recovery. Since GH levels naturally rise and fall throughout the day, accurate testing can reveal useful details about hormonal health and how well training is working. Testing Methods and Accuracy Measuring GH isn't straightforward because of its pulsatile secretion pattern. Standard blood tests aren't enough. Instead, endocrinologists rely on specialized tests: Test Type Purpose Normal Range Approximate Cost IGF-1 Blood Test Primary screening Age/gender specific $70 GH Stimulation Diagnose deficiency >4 ng/mL (adults) Varies GH Suppression Diagnose excess <1 ng/mL Varies Macimorelin Test Oral diagnostic ≤2.8 μg/L Varies Dr. Jennifer Osipoff, a Pediatric Endocrinologist at Stony Brook Children's Hospital, notes: "A random GH level is not a clinically relevant value if assessing for growth hormone deficiency or excess. Instead, endocrinologists will measure insulin-like growth factor 1 (IGF-1), a protein that is made in response to GH secretion." [10] Impact on Athletic Performance GH plays a role in muscle growth, protein synthesis, fat metabolism, and recovery. Studies show that athletes using GH supplementation gained an average of 4.6 pounds of lean body mass [11]. However, GH alone doesn't lead to noticeable improvements in strength or exercise performance. This underscores the importance of focusing on natural ways to optimize GH levels. Natural GH Optimization Tracking GH levels can help adjust training plans. Here are some insights: Women produce about 50% more GH than men over a 24-hour period [9]. GH production decreases by roughly 14% per decade after early adulthood [9]. Anaerobic workouts stimulate more GH release compared to steady-state cardio [9]. Testing Considerations When preparing for GH testing, keep the following in mind: Follow fasting guidelines carefully. Inform your doctor about any medications that could affect results. Schedule tests at times when GH levels are most likely to be measurable. Consider pairing GH testing with IGF-1 measurement for a more complete picture. 4. Thyroid Function Tests Thyroid tests provide important insights for athletes looking to refine their training. These hormones play a key role in metabolism, muscle function, and overall performance, making thyroid health essential for athletic success. Core Thyroid Panel Components Test Type Purpose Indicator TSH (Thyroid Stimulating Hormone) Initial screening test General thyroid function Free T4 Measures active thyroid hormone Direct thyroid output Free T3 Measures active thyroid hormone Reflects metabolic activity Thyroid Antibodies Identifies autoimmune issues Autoimmune conditions How Thyroid Hormones Affect Performance Thyroid hormones impact several areas critical to athletes: Muscle strength, recovery, and protein synthesis Energy production and usage Heart rate and blood pressure regulation Body temperature control Weight stability Dr. Sumedha Chablani, an endocrinologist and clinical assistant professor at NYU Grossman School of Medicine, notes: "Both hypothyroidism and hyperthyroidism can present with fatigue or changes in energy levels, which can impact athletic performance and endurance."[13] Understanding these effects helps athletes address potential issues early. Signs to Watch For Athletes should pay attention to these symptoms for thyroid imbalances: Hyperthyroidism (Overactive Thyroid) Unexplained weight loss with increased appetite Muscle weakness Rapid heart rate Excessive sweating Sleep problems Hypothyroidism (Underactive Thyroid) Persistent fatigue Trouble building or maintaining muscle Slower recovery from workouts Joint and muscle pain Unexplained weight gain If you notice these signs, testing is critical to confirm and address the issue. Testing Tips for Athletes Studies show that 57–90% of hypothyroid patients have elevated creatine kinase (CK) levels [12]. To ensure accurate results: Schedule tests in the early morning. Keep follow-up tests at consistent times. Let your provider know about any medications, supplements, or thyroid concerns. Athletes using androgenic anabolic steroids should be particularly cautious, as these substances can disrupt thyroid function [12]. Supporting Thyroid Health Regular testing can guide adjustments to training and recovery routines. Thyroid hormones are important for muscle function, especially in promoting faster muscle fiber types in muscles with a higher proportion of slow fibers [14]. To maintain thyroid health, athletes should focus on: Prioritizing quality sleep Managing training-related stress Following a well-rounded diet Monitoring thyroid levels regularly Taking care of thyroid health ensures you’re getting the most out of your training efforts. sbb-itb-2f7d8a0 5. IGF-1 Blood Test The IGF-1 blood test measures muscle growth, recovery, and tissue development influenced by growth hormone activity. IGF-1 works alongside growth hormone to support tissue building and muscle protein synthesis. Understanding IGF-1's Role About 75% of IGF-1 is produced in the liver [18]. Unlike growth hormone, which fluctuates throughout the day, IGF-1 levels remain steady, making it a reliable marker for assessing average growth hormone activity [16][17]. IGF-1 Function Impact on Performance Muscle Growth Promotes protein synthesis and muscle development Recovery Activates satellite cells to aid muscle repair Metabolism Improves insulin sensitivity and glucose uptake Bone Health Contributes to bone growth and strength Testing Considerations The United States Anti-Doping Agency (USADA) highlights the importance of medical oversight when it comes to IGF-1: "IGF-1 is produced in response to physiological or pharmaceutical growth hormone (GH), and is responsible for many of the anabolic effects of GH. It can enhance the production of lean muscle as well as aid in recovery time, but when used without medical necessity, exogenous IGF-1 can cause serious harm." [15] Supporting IGF-1 Naturally Boost IGF-1 levels through a diet rich in protein and selenium, paired with progressive strength training. Age-Related Trends IGF-1 levels naturally rise during childhood, peak during puberty, and decline with age. Always refer to age-specific ranges for accurate interpretation. Performance Benefits IGF-1 can improve athletic performance in several ways: Stimulating satellite cells to repair and rebuild muscle fibers Activating the mTOR pathway to increase protein synthesis Reducing protein breakdown by inhibiting FoxO-1 Enhancing insulin sensitivity for better glucose uptake [18] Regular IGF-1 testing can help fine-tune your training plan while ensuring compliance with anti-doping regulations. 6. Estradiol Measurement Estradiol testing is valuable for both male and female athletes aiming to improve their performance. This hormone plays a role in muscle growth, recovery, bone strength, and overall hormone balance, making it an important factor in crafting an effective performance strategy. Normal Reference Ranges Understanding baseline estradiol levels is essential for accurate analysis: Gender/Status Normal Range (pg/mL) Male 10–50 Female (Premenopausal) 30–400 Female (Postmenopausal) 0–30 Impact on Athletic Performance Balanced estradiol levels contribute to muscle strength, recovery, bone density, fat distribution, and mood stability. Studies indicate that estradiol can enhance muscle recovery and strength [20]. Testing Considerations Accurate estradiol measurements require sensitive testing methods. Opt for FDA-approved techniques to ensure reliable results. Warning Signs In men, estradiol levels above 40 pg/mL may indicate potential performance issues. Low estradiol levels can result in: Reduced bone density Slower muscle recovery Sexual health challenges Increased fat accumulation [19] Identifying these imbalances early helps fine-tune training and overall health strategies. Optimization Strategies To maintain healthy estradiol levels: Engage in strength training and maintain a balanced body composition Follow an anti-inflammatory diet rich in vitamin D and calcium Manage stress effectively and prioritize good sleep For athletes using performance-enhancing substances, avoid excessive estradiol suppression, as it can cause negative health effects [19]. Making informed adjustments based on estradiol levels can lead to better training outcomes. Regular Monitoring Incorporate estradiol testing into your routine hormone panel checks to refine your performance strategy and identify any additional markers for optimization. 7. DHEA Blood Test The DHEA blood test is a useful tool for monitoring hormonal health. DHEA, a steroid hormone produced mainly by the adrenal glands, plays a key role in the production of testosterone and estrogen. Understanding DHEA Levels DHEA-S (sulfate) levels naturally vary based on age and gender. They typically peak during puberty and slowly decline as you age. Since lab reference ranges can differ, it's important to review your results with a healthcare provider. How DHEA Affects Performance DHEA can influence athletic performance in several ways: It supports muscle growth when combined with resistance training. It helps reduce muscle damage and soreness with doses of about 100 mg daily. It aids in maintaining hormonal balance as a precursor to testosterone and estrogen [22] [23]. When Should You Test? Athletes might consider testing if they notice signs like unexplained fatigue, reduced performance, difficulty building or maintaining muscle, slow recovery, or other hormonal imbalance symptoms. Women experiencing menstrual irregularities or signs of virilization might also benefit from testing. Identifying these issues early can help you address potential setbacks. What High or Low Levels Mean High DHEA-S levels: Could indicate conditions like congenital adrenal hyperplasia, adrenal tumors, or polycystic ovary syndrome (PCOS). Low DHEA-S levels: May suggest adrenal insufficiency or hypopituitarism. They might also reflect the natural decline in hormone production with age. Tips for Maintaining Healthy DHEA Levels Athletes looking to maintain or improve their DHEA levels can take these steps: Use trusted providers like Discounted Labs for hormone panels at over 2,200 U.S. locations. Get regular tests every three to six months to track changes. Prioritize quality sleep, manage stress, and follow a balanced diet to support overall hormonal health. Key Points to Remember DHEA supplements are banned by the World Anti-Doping Agency (WADA) [21]. Research shows that plasma DHEA-S levels can drop by up to 80% between ages 25 and 75 [22]. Regular blood tests and professional guidance are essential for keeping your hormones in check and staying on top of your performance. 8. LH and FSH Testing LH (Luteinizing Hormone) and FSH (Follicle-Stimulating Hormone) tests offer insight into hormonal balance and endocrine health, especially for athletes and bodybuilders. These hormones, produced by the pituitary gland, play key roles in reproductive health. What Do LH and FSH Do? In men, LH stimulates the Leydig cells in the testes to produce testosterone, which is crucial for sperm production. FSH, on the other hand, supports the development of healthy sperm. For women, LH is involved in triggering ovulation and regulating the menstrual cycle, while FSH helps ovarian follicles grow and mature. Normal LH levels in men aged 20 to 70 usually range from 0.7 to 7.9 IU/L [25]. These functions highlight why testing is important, particularly when performance or recovery issues arise. When Should You Get Tested? Consider testing LH and FSH levels if you notice: Unexplained fatigue or a drop in performance Loss of muscle mass or strength Low sex drive Irregular menstrual cycles (for female athletes) Struggles with workout recovery What Do Test Results Mean? Elevated levels may indicate ovarian or testicular failure, while low levels could point to problems with the pituitary gland or hypothalamus. These imbalances can result from chronic stress, overtraining, poor recovery, or nutritional gaps [26]. Supporting Healthy Hormone Levels To maintain balanced LH and FSH levels, athletes can: Eat a well-rounded diet Adjust training intensity as needed Prioritize recovery time Address insulin resistance through dietary changes [24] Consider a Mediterranean-style diet to support overall hormonal health The Importance of Regular Monitoring Routine testing helps athletes keep track of their hormone levels and address imbalances early. Consulting healthcare professionals ensures proper interpretation of results and helps guide effective interventions. This is particularly important for competitive athletes, as prolonged training stress can disrupt the hypothalamus and reduce LH production [24]. Conclusion Regular hormone testing plays a crucial role for athletes who want to fine-tune their performance. Research shows that up to 85% of people may deal with hormonal imbalances [27], making these tests an important tool for staying in top physical shape. For instance, a testosterone-to-cortisol ratio drop of 30% or more can signal poor recovery and overtraining [28]. Experts like Dr. Zane Hauck and Dr. Mini Sara Cherian highlight how blood tests help athletes adjust workload, recovery, and overall health [1][29]. These insights ensure training programs are based on solid data. To get the most out of hormone testing, athletes should keep these factors in mind: Timing Matters: Tests should account for variables like time of day, hydration, training intensity, and - for women - the menstrual cycle [30]. Diet Adjustments: Results may suggest dietary changes. For example, consuming up to 2 grams of protein per kilogram of body weight and maintaining moderate fat intake can help keep hormone levels in check [30]. Recovery Insights: Monitoring hormones can guide recovery strategies and help avoid overtraining [30]. From testosterone to LH/FSH, each test adds to a comprehensive view of hormonal health. Fortunately, FDA-approved labs across the country now widely offer these tests, making it easier than ever for athletes to maintain optimal hormonal health.

The Cystatin C Blood Test The cystatin C blood test is used to monitor kidney function in people experiencing or suspected to have, kidney disease (1). If a physician suspects that you’re suffering from impaired kidney function they will likely order a cystatin C blood test. The cystatin C test can be done instead of the creatinine or creatinine clearance test in cases where those tests aren’t appropriate (2), such as: In patients with cirrhosis Cases of morbid obesity Malnourishment Reduced or more than "normal" amount of muscle mass Patients taking creatine supplements that are increasing their creatinine and decreasing their estimated creatinine clearance (eGFR) Since the concentration of cystatin C in the blood will not change due to infection or inflammation and isn’t affected by body weight, lean mass, drugs or diet - cystatin C level could be a more reliable indicator of kidney health than creatinine (2). On the other hand, creatinine has been shown to be affected by higher body weight and lean mass. Testing for cystatin may also be useful to detect kidney disease early when the affected person isn’t experiencing many (if any) symptoms, and other test results are normal. What is Cystatin C? Cystatin C is a protein found in almost all the cells in the body. Cystatin C helps to regulate the activity of enzymes needed to break down bigger molecules both inside of and around those cells (3). Cystatin C level in the blood can be measured to determine how well the kidneys are functioning (3). The kidneys, liver, and spleen all work to filter the blood and excrete any waste substances as urine. This filtration process happens in a microscopic structure in the kidneys; the glomerulus (4). Each kidney contains approximately one-million glomeruli that function as tiny sieves to extract waste. The glomerular filtration rate (GFR) rate is a measure of how well the glomeruli are filtering blood (4). If the kidneys and glomeruli are impaired, the GFR could decrease. A decreased GFR can cause certain proteins to accumulate (like cystatin C and creatinine) in the blood. So, the Cystatin C blood test is used to measure circulating levels of cystatin C. The levels of cystatin C in the blood can be used to assess the glomerular filtration rate to indirectly provide an assessment of kidney function. Risk factors for Kidney Disease Over 30 million American adults have kidney disease, but most of them aren’t aware of it (5). This lack of awareness is because people who have kidney disease tend to not experience any symptoms until kidney disease is in its latest stages. This happens when the kidneys are failing or when there are already large amounts of protein present in the urine. If your risk for kidney problems is already high due to hypertension (high blood pressure, diabetes, kidney failure runs in your family or you’re over 60 years of age (6), it’s crucial that you get tested yearly for kidney disease. Symptoms that May Mean a Cystatin C Test is Needed Although the only way to find out if you have kidney disease is to get tested, some symptoms indicate you may be experiencing kidney problems. These are five symptoms that could indicate impaired kidney function (7): 1) You need to urinate more frequently than normal. If you need to urinate more frequently, particularly at night, it can be a sign of kidney disease. When the kidney’s filters aren’t functioning well, it can result in an increased need to urinate. 2) Swollen ankles and feet. A decrease in kidney function may cause sodium retention which can make feet and ankles swell. Lower extremity swelling can also indicate heart or liver disease and circulatory problems. 3) Foamy urine. The presence of bubbles in your urine, especially persistent ones that require several flushes before they go away, could indicate excess protein is present in the urine. This foam may resemble the foam seen when scrambling eggs, since a protein found in urine is the same protein found in eggs: Albumin. 4) Dry and itchy skin. Healthy kidneys perform many critical functions. From removing waste and excess fluid from the body and helping to make blood cells to helping keep bones healthy by maintaining the correct amount of minerals in the blood. When skin becomes dry and itchy, it can be a symptom of mineral or bone disease that can accompany late-stage kidney disease because the kidneys can no longer maintain the correct balance of minerals in your blood. 5) Fatigue. A severe impairment of kidney function may lead to an excess of toxins and impurities in your blood. This accumulation of toxins can result in fatigue and can make it difficult to concentrate. Tiredness and weakness may also be the result of anemia, which is another complication of kidney disease. What Else Can Cause High Cystatin C Levels? While abnormally high cystatin C levels may indicate that you have a potentially serious kidney condition, it’s not the only medical issue that can cause this. Elevated levels of cystatin C could also be caused by conditions like (8,9,10) : Diabetes Cancer HIV Hyperthyroidism Hypothyroidism It’s best to speak to your doctor to understand precisely what the results of a cystatin C test mean for your health.   BUY THE CYSTATIN-C TEST HERE   References Mayo Clinic. Cystatin C with Estimated GFR, Serum. Mayo Clinic Staff. (N.D.) Baxmann, Alessandra Calábria et al. "Influence of Muscle Mass and Physical Activity on Serum and Urinary Creatinine and Serum Cystatin C." Clinical Journal of the American Society of Nephrology: CJASN 3.2 (2008): 348–354. PMC. Web. 25 Nov. 2017. National Kidney Foundation. Cystatin C. NKF Staff. (N.D.) De Martino C., Allen D.J., Accinni L. (1985) Microscopic structure of the kidney. In: Didio L.J.A., Motta P.M. (eds) Basic, Clinical, and Surgical Nephrology. Developments in Nephrology, vol 8. Springer, Boston, MA National Institute of Diabetes and Digestive and Kidney Diseases. Kidney Disease Statistics for the United States. NIDDK Staff. (N.D.) Kazancioğlu, Rumeyza. "Risk Factors for Chronic Kidney Disease: An Update." Kidney International Supplements 3.4 (2013): 368–371. PMC. Web. 25 Nov. 2017. Mayo Clinic. Chronic Kidney Disease. Mayo Clinic Staff. (N.D.) Inker, Lesley A et al. "Performance of Creatinine and Cystatin C GFR Estimating Equations in an HIV-Positive Population on Antiretrovirals." Journal of Acquired Immune Deficiency Syndromes (1999) 61.3 (2012): 302–309. PMC. Web. 25 Nov. 2017. Yaffe, Kristine et al. "Higher Levels of Cystatin C Are Associated with Worse Cognitive Function Among Older Adults with Chronic Kidney Disease: The CRIC COG Study." Journal of the American Geriatrics Society 62.9 (2014): 1623–1629. PMC. Web. 25 Nov. 2017. Madero, Magdalena, and Mark J. Sarnak. "Association of Cystatin C with Adverse Outcomes." Current Opinion in Nephrology and Hypertension 18.3 (2009): 258–263. Print.

High AST and ALT in Bodybuilding: How Weight Training Can Affect Liver Function Understanding Liver Function Tests Liver function tests (LFTs) are essential tools in assessing an individual’s overall health. These tests evaluate the liver’s ability to perform its vital functions, such as detoxification, metabolism, and the production of essential proteins. By measuring specific enzymes and proteins in the blood, LFTs can detect liver damage or disease, allowing for early intervention and treatment. In the context of exercise and muscle damage, LFTs are particularly valuable as they help differentiate between liver damage and muscle damage, which can both cause elevated liver enzymes. Importance of Liver Function Tests in Monitoring Health Liver function tests play a crucial role in monitoring an individual’s health. They provide insights into the liver’s performance and can detect early signs of liver damage or disease. Elevated liver enzymes, such as ALT and AST, can indicate liver inflammation or damage. However, these enzymes can also be released into the bloodstream due to muscle damage from strenuous exercise. By conducting LFTs, healthcare professionals can determine whether elevated liver enzymes are due to liver damage or muscle damage, ensuring accurate diagnosis and appropriate treatment. What Liver Function Tests Measure Liver function tests measure the levels of various enzymes and proteins produced by the liver. The most common LFTs include: Alanine transaminase (ALT): An enzyme that helps convert proteins into energy for liver cells. Elevated levels can indicate liver damage. Aspartate transaminase (AST): An enzyme found in the liver and other tissues, such as the heart and muscles. Elevated levels can indicate liver or muscle damage. Alkaline phosphatase (ALP): An enzyme related to the bile ducts; often increased when they are blocked or inflamed. Gamma-glutamyl transferase (GGT): An enzyme involved in the metabolism of drugs and toxins. Elevated levels can indicate liver or bile duct damage. Bilirubin: A waste product from the breakdown of red blood cells. Elevated levels can indicate liver dysfunction or bile duct problems. These tests help identify liver damage or disease and monitor the effectiveness of treatment, providing a comprehensive picture of liver health. Normal Ranges for Liver Enzymes The normal ranges for liver enzymes can vary slightly depending on the laboratory and the individual’s age, sex, and other factors. Generally, the normal ranges are: ALT: 0-40 U/L AST: 0-40 U/L ALP: 30-120 U/L GGT: 0-60 U/L Bilirubin: 0.1-1.2 mg/dL It’s important to note that these ranges can vary, and a healthcare professional should interpret the results in the context of the individual’s overall health and medical history. Understanding these normal ranges is crucial for accurately interpreting liver function tests and diagnosing potential liver issues. High AST and ALT in Bodybuilding: How Weight Training Can Affect Liver Function Understanding Liver Function Tests Liver function tests (LFTs) are essential tools in assessing an individual’s overall health. These tests evaluate the liver’s ability to perform its vital functions, such as detoxification, metabolism, and the production of essential proteins. By measuring specific enzymes and proteins in the blood, LFTs can detect liver damage or disease, allowing for early intervention and treatment. In the context of exercise and muscle damage, LFTs are particularly valuable as they help differentiate between liver damage and muscle damage, which can both cause elevated liver enzymes. Importance of Liver Function Tests in Monitoring Health Liver function tests play a crucial role in monitoring an individual’s health. They provide insights into the liver’s performance and can detect early signs of liver damage or disease. Elevated liver enzymes, such as ALT and AST, can indicate liver inflammation or damage. However, these enzymes can also be released into the bloodstream due to muscle damage from strenuous exercise. By conducting LFTs, healthcare professionals can determine whether elevated liver enzymes are due to liver damage or muscle damage, ensuring accurate diagnosis and appropriate treatment. What Liver Function Tests Measure Liver function tests measure the levels of various enzymes and proteins produced by the liver. The most common LFTs include: Alanine transaminase (ALT): An enzyme that helps convert proteins into energy for liver cells. Elevated levels can indicate liver damage. Aspartate transaminase (AST): An enzyme found in the liver and other tissues, such as the heart and muscles. Elevated levels can indicate liver or muscle damage. Alkaline phosphatase (ALP): An enzyme related to the bile ducts; often increased when they are blocked or inflamed. Gamma-glutamyl transferase (GGT): An enzyme involved in the metabolism of drugs and toxins. Elevated levels can indicate liver or bile duct damage. Bilirubin: A waste product from the breakdown of red blood cells. Elevated levels can indicate liver dysfunction or bile duct problems. These tests help identify liver damage or disease and monitor the effectiveness of treatment, providing a comprehensive picture of liver health. Normal Ranges for Liver Enzymes The normal ranges for liver enzymes can vary slightly depending on the laboratory and the individual’s age, sex, and other factors. Generally, the normal ranges are: ALT: 0-40 U/L AST: 0-40 U/L ALP: 30-120 U/L GGT: 0-60 U/L Bilirubin: 0.1-1.2 mg/dL It’s important to note that these ranges can vary, and a healthcare professional should interpret the results in the context of the individual’s overall health and medical history. Understanding these normal ranges is crucial for accurately interpreting liver function tests and diagnosing potential liver issues. The Impact of Weight Training on Elevated Liver Enzymes If you have high levels of transaminases, especially alanine transaminase (ALT) and aspartate transaminase (AST), it could mean that your liver is damaged or even has cancer, or it could mean that you are hitting the gym hard. Vigorous exercise, such as intense weightlifting, can also cause a temporary increase in liver enzyme levels. The liver has transaminases, such as ALT levels, to synthesize and break down amino acids and to convert energy storage molecules. The concentrations of these transaminases in the serum (the non-cellular portion of blood) are normally low. However, if the liver is damaged, the liver cell (hepatocyte) membrane becomes more permeable, and some of the enzymes leak out into the blood circulation. A blood test can show elevated liver enzymes. The blood test checks for raised levels of AST and ALT, which are enzymes that the liver releases when it becomes inflamed or damaged. If a doctor finds that a person has raised AST or ALT levels, they are likely to carry out further tests to determine the underlying cause of liver damage, such as acute viral hepatitis, chronic viral hepatitis, or cirrhosis of the liver. Other medical conditions can increase liver enzymes, like hepatitis B or C and a condition that runs in families called hemochromatosis. Chronic liver disease, such as non-alcoholic steatohepatitis (NASH), can also lead to elevated liver enzymes. Liver Enzyme Tests and Exercise The two transaminases commonly measured as part of a liver function panel are alanine transaminase (ALT) and aspartate transaminase (AST). These levels were previously called serum glutamate-pyruvate transaminase (SGPT) and serum glutamate-oxaloacetate transaminase (SGOT). Elevated levels are sensitive to liver injury, meaning that they are likely to be present if there is an injury. However, they may also be elevated in other conditions such as thyroid disorders, celiac disease, and muscle disorders. Elevated liver enzymes can also be a result of drug-induced liver injury, which requires careful interpretation of liver function tests to distinguish from exercise-induced elevations. Additionally, several studies have described enzyme elevations in response to running, whereas only a few have dealt with the effects of weight training. The effects of muscular exercise on clinical chemistry parameters may also vary depending on gender and the fitness level of the individual. But before 2008, no research looked at how weightlifting might affect lab tests that are often used to check how well the liver is working, how long that effect might last, or whether people with weightlifting had yellow eyes or skin, which is a common sign of jaundice. The gamma-glutamyltransferase (GGT) test is another liver enzyme test that can provide valuable insights into liver and bile duct damage. The Effect of Weight Training on Liver Enzyme Tests: Study The Swedish study, which was published in the February 2008 issue of the British Journal of Pharmacology, looked at what happened to liver enzymes in healthy men who did heavy weightlifting just once. The men were not used to doing heavy weightlifting regularly. A second goal was to look into what effect a single bout of intense muscle exercise (weightlifting) had on creatine kinase (CK) and myoglobin, two clinical chemistry markers that show muscle damage. Fifteen healthy men, used to moderate physical activity, not including weightlifting, performed a 1-hour-long weight training program. The following clinical chemistry parameters were measured in the blood: aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LD), gamma-glutamyl transferase (γGT), alkaline phosphatase (ALP), bilirubin, creatine kinase (CK), and myoglobin. These tests were done several times during the first week after exercise and again 10–12 days later. Five out of eight studied clinical chemistry parameters (AST, ALT, LD, CK, and myoglobin) increased significantly after exercise (P < 0.01) and remained increased for at least 7 days post-exercise. Bilirubin, γGT, and ALP remained within the normal range. The liver function parameters, AST and ALT, were significantly increased for at least 7 days after the exercise. In addition, LD and, in particular, CK and myoglobin showed highly elevated levels. These results show how important it is to limit weightlifting before and during clinical studies so that wrong assumptions are not made about how study drugs might hurt the liver. This is particularly important in patients with pre-existing liver disease, where elevated enzyme levels could be misinterpreted. Intensive muscular exercise, e.g., weightlifting, should also be considered as a cause of asymptomatic elevations of liver function tests in daily clinical practice. Muscle Damage and Liver Enzymes Exercise-Induced Muscle Damage and Liver Enzyme Release Exercise-induced muscle damage can lead to the release of liver enzymes, such as AST and ALT, into the bloodstream. This occurs because muscle tissue contains these enzymes, and when muscle damage happens, they are released into the blood. Strenuous exercise, like weightlifting, can cause significant muscle damage, leading to a temporary increase in liver enzymes. This increase can sometimes be misinterpreted as liver damage, but it usually resolves on its own once the muscle damage heals. It’s essential to recognize that muscle damage can also result from other factors, such as muscle conditions, medication use, or other medical conditions. A healthcare professional should evaluate the individual’s overall health and medical history to determine the cause of elevated liver enzymes. In the context of exercise, it’s important to consider the type and intensity of the activity, as well as the individual’s fitness level and medical history. High-intensity exercises, such as weightlifting, can cause more significant muscle damage compared to low-intensity activities like yoga. Understanding this distinction helps in accurately interpreting liver function tests and avoiding misdiagnosis. In conclusion, liver function tests are vital in monitoring an individual’s overall health. Understanding the normal ranges for liver enzymes is crucial for interpreting the results accurately. Exercise-induced muscle damage can lead to the release of liver enzymes, but this increase is usually temporary and resolves once the muscle damage heals. A healthcare professional should evaluate the individual’s overall health and medical history to determine the cause of elevated liver enzymes, ensuring accurate diagnosis and appropriate treatment. Doctors Need to Know that Exercise Can Increase Liver Enzymes Liver function tests are significantly increased for at least 7 days after weight training among men used to moderate physical activity but not used to performing weight training on a regular basis. In line with these findings and to rule out any possible exercise-related effects on liver function tests, it is important to limit weight training for at least one week before the start of clinical trials. The study also shows how important it is to think about weight training and probably other types of intense muscle training as possible causes of liver function tests that are elevated without any symptoms in everyday clinical practice. This will reduce the risk of erroneously attributing changes in liver function tests to a drug effect. Recognizing liver enzyme alteration due to exercise is crucial for accurate diagnosis and treatment. This is especially important for men on testosterone replacement therapy (TRT) who usually work out, and that may have led physicians to wrongly assume that TRT is causing liver abnormalities. Additionally, individuals with high blood pressure should also be cautious when engaging in weight training to avoid any potential impact on liver function. People can work with their doctor to treat NAFLD with weight loss. The doctor may advise a person to make lifestyle changes to lose weight, such as exercising more, eating a healthy, balanced diet, and trying to burn more calories than they consume. Speaking with a nutritionist or even a personal trainer can help someone stay on track with their weight-loss plan. Alcohol consumption can exacerbate the effects of weight training on liver function and should be avoided to maintain liver health. Reference: Br J Clin Pharmacol. 2008 Feb; 65(2): 253–259.  

How to Safely Use PCT After TRT: Stopping Testosterone Replacement Therapy Table of Contents What is Post Cycle Therapy PCT? Why Do Men Stop TRT? Common reasons a man may need to discontinue TRT include: Normalizing Natural Testosterone After Stopping TRT PCT Treatments to Jump Start Natural Testosterone and Sperm Production How to Know if Your PCT Worked? Buy Discounted Lab's Post-PCT Panel  References: There is a common phrase most men will hear when they consider testosterone replacement therapy (TRT); it may be something they hear from friends or often what they read online: “TRT is for life.” There is an element of truth to this statement: when a man has low testosterone, in order to treat it and maintain healthy or optimal levels, he will always need TRT to achieve it. However, saying “it's for life” remains a somewhat inaccurate statement, and this is where we enter into the realm of what is commonly referred to as Post Cycle Therapy or PCT. TRT and anabolic androgenic steroids (AAS) can lead to dysfunction in HPTA (Hypothalamic-Pituitary-Testicular Axis). Supplemental testosterone can inhibit the release of the body's own testosterone production through negative feedback inhibition on LH levels. This feedback inhibition also results in the suppression of FSH levels, leading to the suppression of sperm production (spermatogenesis). During recent years a large surge in testosterone prescriptions and TRT clinics has unfortunately led to many men who have been misdiagnosed with low testosterone yet placed on TRT when it may not have been needed in the first place. If you are one of these men and you are considering discontinuing testosterone treatments, some protocols can help restore your hormone axis. You do not want to stop testosterone "cold turkey," which will lead to unnecessary symptoms that could last for many months. Understanding TRT and Its Impact on the Body Testosterone Replacement Therapy (TRT) can be a game-changer for men with low testosterone levels, but it’s crucial to understand how it impacts the body. TRT involves introducing exogenous testosterone into the body, which can disrupt the natural hormone production process. To grasp the full picture, we need to explore the Hypothalamic-Pituitary-Testicular Axis (HPTA) and how TRT affects it. The Hypothalamic-Pituitary-Testicular Axis and TRT The Hypothalamic-Pituitary-Testicular Axis (HPTA) is a sophisticated system that regulates testosterone production. It starts with the hypothalamus, which produces Gonadotropin-Releasing Hormone (GnRH). This hormone signals the pituitary gland to release Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH). LH and FSH then stimulate the testes to produce testosterone. When you undergo Testosterone Replacement Therapy (TRT), this delicate balance can be disrupted. The introduction of exogenous testosterone can suppress the body’s natural production of LH and FSH, leading to a decrease in the body’s ability to produce testosterone on its own. Impact of TRT on Natural Testosterone Production The impact of TRT on natural testosterone production can be significant. When exogenous testosterone is introduced, it can lead to a suppression of LH and FSH, which are crucial for natural testosterone production. This suppression can result in various symptoms, such as low libido, fatigue, and decreased muscle mass. Over time, prolonged use of TRT can lead to hypogonadism, a condition where the testes are unable to produce sufficient testosterone. This is why understanding the effects of TRT on natural hormone production is essential for anyone considering or currently undergoing TRT. What is Post Cycle Therapy PCT? PCT is a treatment plan after discontinuing anabolic androgenic steroids (AAS). It is a phrase most commonly associated with what we might call “recreational steroid users” (RSU), such as bodybuilders: people who do not need steroid hormones like testosterone for medical reasons but use them for muscular competition advantage. In such cases, the individual will supplement with AAS for a set period of time, known as a steroid cycle, and then discontinue use. As his use of AAS shut down his natural testosterone production, just as it does with TRT, he will often implement a PCT plan for natural production to restart. Such plans will include Selective Estrogen Receptor Modulators (SERMs) or other items, such as the peptide HCG. The goal for the RSU, as eluded to prior, is to regain his natural production of testosterone as quickly and efficiently as possible. There is no guarantee this will work. There is no guarantee he will reach his previous levels before AAS use, although perhaps levels that accurate enough. Then we have the TRT patient; such an individual had low testosterone levels before he began administering exogenous testosterone. The use of testosterone, just as it did with the RSU, will stop his natural production. This is a factor that bothers many men, but let us keep in mind a very significant one: you already had low levels, your body was not able to produce enough, to begin with, and was not going to be able to, or you wouldn’t be on TRT. Nonetheless, there are reasons some men may find they need to discontinue use, and when that occurs, a PCT plan may be in order. Such a plan will not address his primary issue, low testosterone, but the goal here is to get at least some natural production back online. Why Do Men Stop Testosterone Replacement Therapy? Common reasons a man may need to discontinue TRT include: Need for Fertility TRT Cost TRT Side Effects or Health Issues Of the three potential reasons to stop TRT, fertility is the overwhelming reason for most men. Along with suppressing natural testosterone production, TRT can also have a negative impact on sperm production. There was a time in history not that long ago when it was thought exogenous testosterone would be touted as a male contraceptive. This idea died out when many men using testosterone found they were still able to impregnate a female. While many men on testosterone were found to be severely lacking in this department, it wasn’t enough or significant enough to market the hormone as an actual contraceptive. The other common reasons for discontinuing TRT are cost and side effects. These are the least common reasons in comparison to fertility needs or desires, but both are still possible. We all go through points in life where money can get a little tight; loss of a job, unexpected expenses – whatever the reason, if you find you need to stop, considering a PCT plan with your physician will make the transition easier. You’re still going to have low testosterone levels in the end – remember, you already had them, or you wouldn’t have started TRT in the first place – but you’ll hopefully be in a better position than you would be without, and in time, when your situation improves, you’ll be able to jump back on your TRT plan. The same may hold true for the individual who has side effect issues. This will be the least common reason for discontinuation of TRT but certainly within the realm of possibility. You could be one of the rare individuals who cannot control his hematocrit even with regular therapeutic phlebotomy. You could be someone that has other health concerns and, for whatever reason, need to discontinue use until you figure out what’s going on with your body. Hormonal imbalances, such as elevated estrogen levels, can also occur when stopping TRT, leading to conditions like gynecomastia. As was with the individual who was experiencing income issues, a PCT plan may be in order. Preparing for TRT Discontinuation Deciding to discontinue TRT is a significant step and should be approached with caution. One of the most critical aspects of stopping TRT safely is to do so under the guidance of a medical professional. Abruptly stopping TRT can lead to severe withdrawal symptoms and a dramatic drop in testosterone levels, which can be detrimental to your health. Gradual Tapering Under Medical Supervision When it comes to discontinuing TRT, gradual tapering is the safest approach. This process involves slowly reducing the dosage and frequency of testosterone administration to allow the body to adjust and begin producing testosterone naturally again. A healthcare provider can create a personalized tapering schedule based on factors such as the dosage and duration of your TRT use. This might involve reducing the amount of testosterone you inject or apply through gels over a set period. Regular check-ups with your healthcare provider are crucial during this time to monitor your progress and make any necessary adjustments to your tapering plan. This careful and monitored approach helps minimize withdrawal symptoms and supports the body’s natural transition back to producing testosterone on its own. By understanding the impact of TRT on your body and following a medically supervised tapering plan, you can safely discontinue TRT and support your body’s return to natural testosterone production. Normalizing Natural Testosterone After Stopping TRT For most men, studies have shown that for men who stop TRT, natural testosterone production can normalize within three months or longer, and spermiogenesis in well over a year. This is certainly not optimal when conception is the goal, which leads to the possible need for a PCT protocol. Post cycle therapy (PCT) is crucial in maintaining and recovering natural testosterone levels after using performance-enhancing drugs, as it helps enhance the body's own testosterone production. PCT Treatments to Restore Hormonal Balance and Jump Start Natural Testosterone and Sperm Production The use of the SERMs has been shown to increase testosterone levels to baseline in as little as 2-4 weeks. Studies have also shown spermiogenesis to improve significantly within 3-6 months. Clomid as we can easily see, greatly improves the time frames of recovery of these two important factors related to conceiving (testosterone and semen). PCT is crucial to restore hormonal balance, helping individuals recover from the use of anabolic steroids by promoting natural testosterone production and mitigating adverse effects caused by hormonal imbalances. HCG is another item commonly used in PCT for fertility purposes. HCG PCT has the ability to stimulate both testosterone production and spermiogenesis. It is not uncommon for fertility specialists to try both Clomid and HCG and, in some cases, in conjunction with one another. Unfortunately, there is much controversy among many fertility specialists regarding how much HCG should be administered for this purpose. While many physicians will prescribe SERMs in the range of 25-50mg per day to every other day, commonly prescribed HCG doses can run anywhere from 1000iu per day to 2500iu or even larger doses split into every other day schedules. Other common drugs used in this treatment, but to a lesser extent, include the SERM Tamoxifen Citrate, best known by its most notable trade name, Nolvadex. Treatments usually requires 4 weeks. Unfortunately, for some men, a PCT plan that includes some or all of these medications will not work. A HCG PCT plan is most likely to work in a TRT patient who is receiving treatment due to secondary hypogonadism. If a PCT plan has not worked – testosterone levels and sperm count have not increased – it is likely that the individual has primary hypogonadism, and as a result, will be best served (quality of life) by remaining on TRT. It’s imperative to note: this individual had primary hypogonadism prior to beginning TRT, he did not obtain it because of TRT. How to Know if Your PCT Worked? After going through PCT, physicians tend to check your testosterone blood levels and upstream hormones like LH and FSH to determine if your hormone axis has been restored. Discounted Labs has created a Post PCT Lab Test Panel that makes it easy for men to know if their PCT has successfully worked. This lab test panel is designed to measure the health and recovery of the Hypothalamic-Pituitary-Testicular Axis (HPTA) after attempting to normalize it spontaneously or with the use of Post Cycle Therapy (PCT) (with the use of clomiphene, hCG, and other treatments) It is suggested that this panel be done no sooner than 4 weeks after PCT cessation and in a fasting state (morning time). Lab tests included in the post-PCTest Panel: Ultra Sensitive Estradiol Test by Liquid Chromatography/Mass Spectrometry (LC/MS assay used to measure estradiol in men more accurately estradiol in men) Total and Free Testosterone LC/MS- No upper limit Luteinizing Hormone (LH) (responsible for activating Leydig testicular cells to produce your own testosterone). This hormone is shut down by testosterone replacement or AAS. Follicle Stimulating Hormone (FSH) (Responsible for activating Sertoli testicular cells to produce sperm). This hormone is shut down by testosterone replacement or AAS. CBC - Complete Blood Count (Includes hematocrit- red blood cell volume) CMP - Comprehensive Metabolic Panel (Includes liver and kidney function, glucose and electrolytes) For any man, simply discontinuing the use of testosterone can be difficult, to put it mildly. Your testosterone levels will completely bottom out when going the cold-turkey route, and this often. This severe sexual dysfunction, decreased energy, and even depression, to name a few of the consequences. Your levels may go up enough to at least function, to a degree, but it's going to take an enormous amount of time, as previously discussed. Cutting this time down significantly, and giving your body a boost in testosterone during the therapy process, is the only means of discontinuation that makes any sense, meaning some form of a PCT plan is a sensible approach. Buy Discounted Lab's Post-PCT Panel  References: Diagnosis and Management of Anabolic Androgenic Steroid Use Testosterone Use in the Male Infertility Population: Prescribing Patterns and Effects on Semen and Hormonal Parameters How to Stop TRT Safely

How Long to Fast Before a Testosterone Blood Test: Do You Need To? About 5 million American men suffer from low testosterone levels. This is also known as hypogonadism and can have significant effects on your life. Hypogonadism (testosterone deficiency) is diagnosed by running multiple tests. Patients get one or more testosterone tests to measure their levels. But recent studies found out that your testosterone levels can be affected if the tests were done while fasting. In other words, having a meal before a testosterone test can change the results. Read on to find out more about the correlation between testosterone levels and fasting. How to Test for Low Testosterone? What is the correlation between fasting and testosterone? Study 1 - Testosterone went down significantly after an oral glucose load Study 2 - Eating a meal can lower testosterone levels by a lot Key Takeaway for Future Testosterone Testing Protocols About 5 million American men suffer from low testosterone levels. This is also known as hypogonadism and can have significant effects on your life. Hypogonadism (testosterone deficiency) is diagnosed by running multiple tests. Patients get one or more testosterone tests to measure their levels. But recent studies found out that your testosterone levels can be affected if the tests were done while fasting. In other words, having a meal before a testosterone test can change the results. Read on to find out more. What is a Testosterone Test? A testosterone test is a medical test to measure the level of testosterone in your blood. Testosterone is a hormone produced by the adrenal glands and gonads (ovaries in females and testes in males) that is important for the development and maintenance of male reproductive tissues, bone density and muscle mass. In females, testosterone is present in smaller amounts and helps in the growth and development of bones and muscles. Why is a Testosterone Test Performed? A testosterone test is performed to diagnose and monitor various medical conditions related to abnormal testosterone levels. The test can help identify: Testosterone Deficiency (Hypogonadism): In males, low testosterone levels can cause low sex drive, fatigue, and decreased muscle mass. Testosterone Excess (Hyperandrogenism): In females, high testosterone levels can cause excessive hair growth, acne, and irregular menstrual cycles. Polycystic Ovary Syndrome (PCOS): This common endocrine disorder in females is characterized by high testosterone and androgen excess. Adrenal Gland Disorders: Conditions like Cushing’s syndrome can cause abnormal testosterone production. Monitoring Therapy: It’s also used to monitor testosterone levels in individuals undergoing testosterone replacement therapy or androgen deprivation therapy. Preparing for a Testosterone Test To prepare for a testosterone test: Schedule the Test in the Morning: Testosterone levels are highest in the morning, so schedule your test early in the day. Fasting: Don’t eat or drink anything but water for at least 8 hours before the test. Fasting will give you accurate results. Inform Your Doctor: Tell your doctor about any medications or supplements you are taking, as they may affect testosterone levels. Wear Comfortable Clothes: Wear loose and comfortable clothes and avoid tight sleeves that may make it hard to draw blood. Plan Your Visit: You will be at the testing facility for about 30 minutes, but the blood draw will only take a few minutes. By doing these you can get the most accurate testosterone test results. How to Diagnose Low Testosterone? Testosterone levels are highest in the morning for all healthy males. They start to drop after 11 am and continue to drop towards the end of the day. Testosterone tests are done in the morning because that’s when the levels are highest. If a person sees the classic signs of low testosterone, a test might be required to check this out. These signs are low sex drive, poor concentration, fatigue and even depressive symptoms. But multiple tests are needed to confirm if the person is hypogonadal or not. A testosterone levels test measures the amount of testosterone in a blood sample. For example, your doctor might check your FSH and LH levels. These hormones are produced by the pituitary gland and trigger the testosterone and sperm production in the testicles. Depending on the lab, a healthy male should have a testosterone measurement between 350 ng/dl and 1,250 ng/dL. If below 350 ng/dl and you have low testosterone symptoms, you might be considered hypogonadal. Testosterone levels vary depending on the time of day, diet, age, fitness level and other factors. As mentioned earlier, testosterone tests are done in the morning when testosterone is at its peak. Labs and doctors don’t require patients to fast before a testosterone test. But some studies suggest that fasting before a testosterone test can affect the results. What’s the connection between Fasting and Testosterone Levels? In simple terms, fasting means not eating for a certain period of time, usually 8 to 12 hours. This also includes not drinking anything that makes your organs work to process them, like drinks, milk, etc. Many blood tests require patients to fast before drawing a sample. A standard glucose test is a good example of this. If you eat something and then do a glucose test, you might be labeled as diabetic. That’s because your body didn’t get a chance to process the glucose in your blood, and it will show up in the test. Scientists believe that fasting is also important when testing testosterone through blood tests. In short, eating before your test will temporarily lower your testosterone levels. This can lead to a false diagnosis of hypogonadism if your normal T level is around 400-500 ng/dL. Such findings also mean retesting subjects who were initially diagnosed with low testosterone. Let’s look at a few studies and see the correlation between fasting and testosterone tests in more detail. You’ll see how a glucose load or a full meal can affect the total and bioavailable testosterone levels hours after ingestion. Study 1 - Testosterone Decreased Significantly After an Oral Glucose Load This study was done on 74 men. The average age of the participants was around 50, give or take a few years. The study was done in 2012, and it was a standard 75-g oral glucose tolerance test. An oral glucose tolerance test measures how well your body can process glucose in the blood after you drink a sweet drink they give you at the lab. If you process it fast, your glucose tolerance is good. If it takes too long to process, it’s usually associated with diabetes or other health problems. Almost 60% of the men in the study had normal glucose tolerance. More than 10% were newly diagnosed with diabetes, and about 30% had impaired glucose tolerance. Blood was drawn from each participant at the start of the study and at 30, 60, 90, and 120 minutes, respectively. Other hormones and substances were also measured, such as insulin, leptin, sex hormone-binding globulin (SHBG), and total testosterone levels. None of these individuals had low testosterone at the start of the study. But the results were surprising. The study showed that testosterone levels decreased by 25% after glucose ingestion. That’s a big drop considering most of the participants had normal glucose tolerance. To put it into perspective, if an individual starts with an average testosterone level of 500 ng/dl, a 25% decrease would bring him down to 375 ng/dl. That’s close to the bottom of the normal testosterone range. Interestingly, the testosterone suppression was still present after 120 minutes when blood samples were drawn for the last time. 10 of the participants could qualify for hypogonadism at the end of the study as their testosterone levels went below the baseline. This study shows how important it is to test for testosterone in a fasted state. A simple glucose load can lower total testosterone levels and qualify someone for hypogonadism. Study 2 - Eating a Meal Can Decrease Testosterone Levels Let’s look at another study that shows the correlation between testosterone levels and fed or fasting state. This study shows how a 550-calorie meal of protein, fat and carbohydrates can affect testosterone levels. 11 healthy men participated in this study. They were non-smokers, had no medical treatment, and had normal BMI. The average age was 43 years, and they had no significant medical history. In the first part of the study, the participants were given a 550-calorie meal of buttermilk, cheese, ham, orange juice, and other foods. Blood was drawn at various intervals. The study also measured other hormones such as LH, SHBG, and glucose. Free testosterone, the unbound fraction and biologically active, was also measured. The participants finished the meal in about 15 minutes. The foods were varied, as the study designers wanted to mimic a meal that most men would eat on a daily basis. Before the meal, the participants were told to fast for 12 hours. They were also instructed not to have sex or do any strenuous exercise that would affect their testosterone levels. The same procedure was repeated a few weeks later with the same participants. This time they only fasted for 12 hours and didn’t eat after. Blood was drawn in the fasting state, and all other parameters were the same. When the two experiments were compared, the results were striking. In both groups, the initial fasting testosterone levels were the same. LH and SHBG were unchanged. But in the fed group, testosterone levels decreased 15 minutes after meal ingestion. And 30 minutes after the meal. Other hormones and parameters were the same; just total and bioavailable testosterone levels went down. Upon reviewing the results, the experts found out that the decrease in testosterone was 30%. This was true for all participants with no exceptions. This study shows how testing for testosterone in a fasted state is different from testing in a fed state. Takeaway for Future Testosterone Testing Protocols The scientific literature on sexual medicine says that food intake can affect testosterone levels. But the standard testosterone test protocol doesn’t require fasting before the test. The studies above open up a potentially big change in how testosterone tests are done. Also, there was no significant difference in LH, SHBG, and other hormones among the participants. This means the hypothalamic-pituitary-testicular (HPT) axis was not really affected by food or glucose intake, but testosterone production was. It’s believed that insulin, a hormone produced by the pancreas when we eat to process glucose, can temporarily decrease testosterone production at the testicular level. If you think you have low testosterone, order these testosterone tests online at an affordable price and see how your hormones are doing.   References : Testosterone decrease after a mixed meal in healthy men independent of SHBG and gonadotropin levels. Andrologia. Volume 44, Issue 6 December 2012. Pages 405-410. Abrupt decrease in serum testosterone levels after an oral glucose load in men: implications for screening for hypogonadism. Clin Endocrinol (Oxf) 2013 Feb;78(2):291-6. Testosterone Test - Testing.com Testosterone as a Fasting Blood Test? - Grand Rounds in Urology Testosterone blood test – how to prepare for your blood test | healthdirect Is a fasting testosterone level really necessary for the determination of androgen status in men? - PubMed

Are you a bodybuilder looking to maximize your performance and ensure optimal health? Regular bodybuilding blood work is key to achieving these goals. It provides valuable insights into your body's functioning, allowing you to make informed decisions about your training, nutrition, and supplementation. In this blog, we will explore the importance of regular blood work for bodybuilders and how it can help you strike the right balance between performance and health. We'll also address common factors that can affect blood test values in bodybuilders, as well as essential lab tests that every bodybuilder should consider. Don't miss out on this valuable information that can take your bodybuilding journey to new heights. Table of Contents The Importance of Regular Bodybuilding Blood Work Maximizing Performance and Health: A Balance Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care Factors that Affect Blood Test Values in Bodybuilders Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Resistance Exercise Can Increase Liver Enzymes Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol High Doses of Anabolics Can Decrease Ferritin in Bodybuilders Understanding Essential Bodybuilding Blood Work Tests Complete Blood Count (CBC) Hematocrit Comprehensive Metabolic Panel (CMP) Lipid Test Panel Cystatin C with EGFR Kidney Test eGFR Kidney Test GGT Liver Test Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Free Testosterone (Equilibrium Ultrafiltration) Test Ultra-Sensitive Estradiol (E2) Test Prolactin Test DHT Test IGF-1 Test Ferritin Test How do these tests help optimize bodybuilding performance? The role of these tests in muscle gain, fat loss, and quality of life How can bodybuilders prepare for these tests? Why is regular bodybuilding blood work essential? How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com Conclusion   The Importance of Regular Bodybuilding Blood Work Regular bodybuilding blood work plays a crucial role in monitoring hormone levels and overall health, including high blood pressure. By conducting regular blood tests, bodybuilders can identify potential health issues before they become serious. Additionally, blood work provides valuable insights for optimizing nutrition and supplementation, leading to better performance. Tracking blood markers allows bodybuilders to make informed decisions about their training and recovery strategies. Ultimately, regular blood work is essential for long-term health and longevity in the world of bodybuilding. By staying on top of blood markers like testosterone, hormone levels, glucose, and kidney function, bodybuilders can ensure they are in optimal condition to achieve their goals. Maximizing Performance and Health: A Balance Regular monitoring of bodybuilding blood work, including testosterone tests, is crucial for bodybuilders to maximize their performance and maintain good health. Through regular blood tests, bodybuilders can monitor hormone levels, nutrient deficiencies, and overall organ function. This information is invaluable in making informed adjustments to diet, supplements, and training routines. By maintaining a balance between performance and health, bodybuilders can optimize their training and achieve their goals. Prioritizing health through regular blood work is essential for long-term success and sustainable progress in bodybuilding. It allows bodybuilders to identify any potential imbalances and make the necessary adjustments for optimal performance. By utilizing comprehensive metabolic panels, lipid panels, and hormone level tests, bodybuilders can ensure that their training is effective and their bodies are functioning optimally. Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses   According to a scientific review, the use of anabolic steroids has the following ergogenic effects: ■ Increase in lean body mass ■ Increase in muscle cross-sectional area ■ Decrease in body fat percent ■ Increase muscle strength & power ■ Enhance recovery between workouts ■ Enhance recovery from injury ■ Increase in protein synthesis ■ Increase in muscle endurance ■ Increase in erythropoiesis, hemoglobin, and hematocrit ■ Increase in bone mineral density ■ Increase in glycogen storage ■ Increase in lipolysis ■ Increase in neural transmission ■ Reduced muscle damage ■ Increase in pain tolerance   However, the use of these agents could have the following side effects: Cardiovascular ■ Lipid profile changes ■ Elevated blood pressure ■ Decreased myocardial function Increased in blood viscosity due to high hematocrit Dermatological ■ Acne ■ Male pattern baldness Endocrine ■ Gynecomastia ■ Decreased sperm count ■ Testicular atrophy ■ Impotence and transient infertility Hepatic ■ Increased liver enzymes Renal Decreased kidney function Genitourinary Males ■ Reduced sperm counts ■ Decreased testicular size Females ■ Menstrual irregularities ■ Clitoromegaly ■ Masculinization Males and Females ■ Gynecomastia ■ Libido changes Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care The stigma surrounding performance-enhancing drugs (PEDs) frequently makes bodybuilders reluctant to seek medical attention. Many bodybuilders are reluctant to disclose their PED use due to fear of judgment or a lack of understanding from healthcare professionals. This can impede their access to important resources such as regular blood work, which is vital for monitoring health and performance. Healthcare professionals need to be knowledgeable about the potential risks and side effects associated with PEDs in order to provide appropriate care and guidance. Open communication and support between bodybuilders and healthcare professionals can foster collaboration for optimizing performance while minimizing health risks.   Factors that Affect Blood Test Values in Bodybuilders Muscle damage and inflammation can impact blood test results in bodybuilders, as the body's response to intense training can cause temporary changes in certain blood markers. Additionally, high protein intake, which is common among bodybuilders, may affect kidney function and liver enzymes but is not clinically significant, which is concerning to doctors not familiar with this fact. Steroid use can also lead to hormonal imbalances and abnormal blood test results. Dehydration, which can occur during intense workouts or when bodybuilders are cutting weight, can cause changes in electrolyte and blood cell levels. Weight training can also increase certain live enzymes in a non-clinical way. Supplements like creatine can falsely increase serum creatinine, which can alarm certain physicians. It is important for bodybuilders to address any nutritional deficiencies identified through blood testing, as these deficiencies can impact performance and overall health. Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Anabolic steroid use without testosterone can result in a decline in testosterone levels among bodybuilders, leading to low testosterone, or TSH. Testosterone plays a crucial role in muscle growth, recovery, and overall performance in bodybuilding. To ensure optimal health and performance, bodybuilders should regularly monitor their testosterone levels. Consulting with a healthcare professional can help them effectively manage their hormone levels. It is essential to maintain balanced testosterone levels to avoid negative side effects and maximize results. By being proactive in monitoring testosterone levels, bodybuilders can optimize their performance and achieve their desired outcomes. Resistance Exercise Can Increase Liver Enzymes Intense resistance exercise can result in temporary elevations in liver enzymes, including alkaline phosphatase, which is a normal response to muscle damage and repair. It is crucial for bodybuilders to inform their healthcare provider about their exercise routine before getting blood work done. Although elevated liver enzymes due to exercise are typically harmless and resolve on their own, regular monitoring of liver enzymes is essential for bodybuilders to ensure optimal health and performance. By keeping track of liver enzyme levels, bodybuilders can identify any abnormalities early on and take appropriate actions to maintain their liver function. Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Creatine supplementation can temporarily decrease kidney function markers, leading to lower creatinine and potassium levels in bodybuilders. It is important for bodybuilders to inform their healthcare providers about any dietary supplements before undergoing blood tests. Once creatine supplementation is discontinued, creatinine and potassium levels can normalize. However, monitoring kidney function through multiple biomarkers is essential for an accurate assessment. By incorporating these measures, bodybuilders can ensure that their kidney function is accurately evaluated. Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol Certain oral anabolic steroids used by bodybuilders have the potential to increase liver enzymes and decrease HDL cholesterol levels, leading to an increase in total cholesterol and low-density lipoprotein. Regular blood tests are vital for bodybuilders who use these oral steroids to monitor their impact on liver function and cholesterol levels. Elevations in liver enzymes can be a sign of liver damage, while decreased HDL cholesterol levels pose a risk for cardiovascular health. Working with a healthcare professional is essential to mitigating these potential risks associated with the use of oral anabolic steroids. By closely monitoring liver health and cholesterol levels, bodybuilders can make informed decisions about their supplementation and take necessary steps to protect their overall health. High Doses of Anabolics Can Decrease Ferritin in Bodybuilders High doses of anabolic steroids can result in decreased ferritin levels among bodybuilders, impacting their overall performance. Ferritin plays a crucial role as a protein that stores iron, and deficiencies can have negative effects on muscle growth and health. To optimize supplementation and monitor ferritin levels, regular blood tests are essential. Consulting with a healthcare professional can provide personalized guidance on maintaining optimal ferritin levels and growth hormone levels. It is important for bodybuilders to be aware of the potential impact of high doses of anabolic steroids on ferritin levels and take proactive measures to ensure balanced hormone levels and nutrition. By prioritizing the monitoring of ferritin levels, bodybuilders can support their muscle growth and overall well-being. Understanding Essential Bodybuilding Blood Work Tests Regular blood work is vital for bodybuilders to monitor their health and optimize their performance. Key lab tests for bodybuilders include hormone levels, liver function, kidney function, and thyroid function. These tests can help identify potential health issues and allow for adjustments in training and nutrition plans. Working with a healthcare professional who specializes in sports medicine or bodybuilding is beneficial to ensure an accurate interpretation of the results. By regularly monitoring hormone levels, such as testosterone and estradiol, bodybuilders can address any imbalances and make necessary adjustments to their supplementation or hormone replacement therapy. Additionally, liver function tests like ALT and AST can assist in identifying any liver abnormalities or damage that may result from the use of anabolic steroids. Kidney function tests, like creatinine and BUN, are crucial for assessing the impact of intense training and supplement use on the kidneys. These lab tests provide valuable insights into a bodybuilder's health and play a crucial role in maintaining optimal performance, including CMP. Complete Blood Count (CBC) A complete blood count (CBC) test panel measures several components of your blood, including Red blood cells, which carry oxygen, White blood cells, which fight infection; hemoglobin, the oxygen-carrying protein in red blood cells; hematocrit, the proportion of red blood cells to the fluid component in your blood (which is correlated with blood thickness); and Platelets, which help with blood clotting. Hematocrit All androgens, like testosterone and AAS, can increase red blood cells and their proportion in the blood (hematocrit), increasing blood thickness (erythrocytosis). High hematocrit can cause high blood pressure, headaches, and cardiovascular risks. This panel is essential since it determines when you reach a hematocrit of 53, indicating that blood donation or therapeutic phlebotomy is needed. Comprehensive Metabolic Panel (CMP) The comprehensive metabolic panel, or CMP panel, consists of 14 blood tests that are an initial medical screening tool to review overall health. The CMP blood test panel checks for glucose, kidney function, liver function, electrolytes, and fluid balance. Fasting IS REQUIRED. Lipid Test Panel This panel includes LDL (bad cholesterol), HDL (good cholesterol), and triglycerides (fatty acids dissolved in the blood). Higher doses of T and AAS can increase LDL and decrease HDL and triglycerides. Severely decreased HDL may cause cardiovascular issues in the long term. FASTING IS REQUIRED. Cystatin C with EGFR Kidney Test Since higher muscle mass, protein intake, and creatine supplementation can all affect creatinine as the primary variable, cystatin C is a more accurate way to assess kidney function in people with higher muscle mass. Another one of the measures of kidney function is the estimated glomerular filtration rate (eGFR). The glomerular filtration rate describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCRCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit of time and is a useful measure for approximating the GFR. eGFR under 60 may indicate issues that are affecting kidney function. eGFR Kidney Test The eGFR kidney test is an important tool for bodybuilders to monitor their kidney health and ensure optimal performance. By measuring how well the kidneys are functioning, this test can help detect any potential kidney issues that may arise, affecting metabolism. It is crucial for bodybuilders to regularly check their eGFR levels, as low levels under 60 can indicate kidney damage or impaired kidney function, which can have a negative impact on performance. Maintaining a healthy eGFR level is essential for overall health and athletic performance. Consulting with a healthcare professional is recommended for interpreting eGFR results and taking the necessary steps to support kidney health. GGT Liver Test The GGT blood test looks for an enzyme, or protein, called gamma-glutamyl transpeptidase (GGT) in your blood. GGT is found in liver cells. This test helps your doctor look for damage to your liver or its ducts. It can also help tell the difference between liver and bone disease if your results from a different blood test called alkaline phosphatase are abnormal. Higher than-average test results could indicate liver damage from diseases such as hepatitis, cirrhosis, tumors, or pancreatic cancer. The good thing about GGT (unlike liver enzymes included in the CMP like AST and ALT) is that resistance exercise does not affect its value, so it is a more accurate way to detect liver disease in bodybuilders. Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Men with high testosterone cannot use the regular total testosterone test based on immunoassays since it has an upper limit of 1,500 ng/dL. The LC/MS testosterone test does not have an upper limit. Also, some labs offer calculated free testosterone instead of the equilibrium ultrafiltration-based one, which is more accurate for this critical variable. Free Testosterone (Equilibrium Ultrafiltration) Test The equilibrium ultrafiltration test is a precise method used to measure the amount of unbound testosterone in the bloodstream. Free testosterone plays a crucial role in muscle growth, strength, and overall performance for bodybuilders. Monitoring free testosterone levels can provide valuable insights into potential imbalances or deficiencies that may impact training, recovery, and hormone balance. By regularly testing free testosterone, bodybuilders can optimize their training and supplement plans to maximize their performance and health. This test, along with other essential lab tests, helps bodybuilders maintain optimal hormone levels and ensure their body is functioning at its best. Ultra-Sensitive Estradiol (E2) Test The commonly used estradiol test may overestimate estradiol. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This ultrasensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation. Furthermore, DHT analogs like oxandrolone may dramatically decrease estradiol, causing joint aches and other low estradiol issues. Note: 0.4 percent of total testosterone aromatizes to estradiol. This is the body's way of balancing testosterone's negative effect on lipids with estradiol's beneficial effect. If your total testosterone is high, so is your estradiol. Be very careful in assuming that an aromatase inhibitor is needed. For more information, click on the effect of high and low estradiol on men's health. How to predict estradiol for different testosterone doses. Prolactin Test Many bodybuilders worry about increased prolactin since it has been associated with erectile dysfunction. Regular monitoring of hormone levels is essential for bodybuilders, and the prolactin test plays a crucial role in this process. This test helps detect potential imbalances that can impact performance and overall health. Elevated prolactin levels may indicate issues such as reduced testosterone production or the presence of pituitary gland tumors. Therefore, it is vital for bodybuilders to undergo regular prolactin testing to optimize their performance and maintain their overall well-being. However, interpreting the results accurately requires consultation with healthcare professionals. By keeping prolactin levels in the optimal range, bodybuilders can enhance muscle growth, support recovery, and promote their overall physical and mental well-being. DHT Test This test measures the amount of dihydrotestosterone (DHT) in the blood. Low DHT has been associated with low libido, and high DHT has been linked to acne, hair loss, and benign prostatic inflammation in a minority of men. DHT test (LC/MS) measures dihydrotestosterone levels, a hormone linked to muscle growth and male characteristics. It helps bodybuilders evaluate hormonal balance for enhanced performance. Monitoring DHT levels provides insights into potential side effects or risks associated with supplements or steroid use. Regular testing tracks progress and informs decisions on training and supplementation. Discussing results with healthcare professionals creates personalized strategies for goals. IGF-1 Test Insulin-like Growth Factor 1, also known as IGF-1, is used as a biomarker for blood levels of human growth hormone. It is a hormone that the liver and other tissues produce that affects glucose metabolism and growth-promoting activities. Low IGF-1 may impede muscle growth. The IGF-1 test, performed using LC/MS, is a crucial tool for bodybuilders to assess their performance and overall health. This test measures the levels of insulin-like growth factor-1, a hormone that plays a vital role in muscle growth and repair. By analyzing IGF-1 levels, bodybuilders can determine whether they have optimal hormone levels for performance and recovery. Low levels of IGF-1 may indicate potential limitations in muscle growth or underlying health issues. Ferritin Test Ferritin is a protein that stores iron. Red blood cells need iron to form and carry oxygen around your body. Low levels of ferritin lead to anemia. TRT and anabolic steroids make the body make more red blood cells (erythrocytosis). This increased production decreases iron stores and ferritin. Testosterone has been shown to decrease ferritin. Men who use TRT and anabolic steroids and have high hematocrit (increased blood thickness due to TRT or anabolic steroids) frequently donate blood or undergo therapeutic phlebotomy to lower hematocrit. There is a loss of around 30 points of ferritin during every donation. Low ferritin can cause fatigue, restless leg syndrome, muscle aches, and other issues. How do these tests help optimize bodybuilding performance? Bloodwork tests play a crucial role in optimizing bodybuilding performance. They provide valuable insights into hormone levels, nutrient deficiencies, and overall health. By identifying imbalances or deficiencies, bodybuilders can make targeted adjustments to their diet and supplementation, enhancing muscle growth, recovery, and overall performance. Regular blood work helps track progress and make necessary adjustments to training and nutrition protocols. The role of these tests in muscle gain, fat loss, and quality of life Blood tests play a vital role in bodybuilding, specifically when it comes to muscle gain, fat loss, and overall quality of life. These tests provide valuable insights into hormone levels, such as testosterone and cortisol, which are crucial for optimal muscle growth and fat loss. By monitoring these blood markers, bodybuilders can optimize their recovery and prevent overtraining. Additionally, blood work can reveal any nutrient deficiencies that may be hindering progress in muscle gain or fat loss. Moreover, assessing liver and kidney function through blood tests ensures the overall health and longevity of bodybuilders. Regular blood work is essential for identifying potential health risks and allowing for timely intervention to maintain a high quality of life. How can bodybuilders prepare for these tests? To prepare for bodybuilding blood work, it's important for bodybuilders to stay hydrated, avoid strenuous exercise or heavy lifting 48 hours before the test, follow any fasting requirements given by the healthcare provider, and inform them about any supplements or medications being taken. Why is regular bodybuilding blood work essential? Regular monitoring of crucial parameters is essential for bodybuilders. It helps ensure optimal performance and overall health. By tracking hormone levels, liver function, and kidney function, bodybuilders can make informed decisions about their training, nutrition, and supplementation strategies. Regular blood work also provides a baseline for comparison and allows assessment of the effectiveness of lifestyle choices on health and performance. How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com To buy affordable bodybuilder blood work on DiscountedLabs.com, simply visit the website and create an account. Then, search for the specific bodybuilder blood work panel you need and add it to your cart. Proceed to checkout and apply any available discount codes before completing your purchase. Bodybuilder Panels Sold by DiscountedLabs.com Bodybuilder Blood Test Panel- Basic Bodybuilder Blood Test Panel- Beginner Bodybuilder Blood Test Panel- Comprehensive Conclusion Regular bodybuilding blood work is essential for maximizing performance and maintaining good health. It helps bodybuilders identify any imbalances or potential health risks caused by their training regimen and performance-enhancing agents. Understanding the importance of these tests and regularly monitoring key parameters such as testosterone levels, kidney function, liver enzymes, and lipid profiles can help bodybuilders optimize their muscle gain, fat loss, and overall quality of life. To ensure accurate results, it is important for bodybuilders to prepare for these tests by following specific guidelines. Regular monitoring of these parameters allows bodybuilders to make adjustments to their training and nutrition plans, minimizing potential risks and improving long-term outcomes. DiscountedLabs.com offers affordable bodybuilder blood work, making it easier for individuals to access these crucial tests. Take charge of your bodybuilding journey and prioritize your health and performance with regular blood work.        

Maximize Benefits Today: Bodybuilder Blood Test Results What are the key parameters that bodybuilders should look for in their blood test results? Key parameters bodybuilders should focus on in blood test results include testosterone levels, liver function markers, kidney function markers, iron levels, and cholesterol levels. Monitoring these can help optimize performance, prevent injuries, and ensure overall health while pursuing bodybuilding goals. Bodybuilders who take testosterone and anabolic androgenic steroids (AAS) must be smart about maximizing benefits and limiting short- and long-term side effects while exercising and eating well to achieve respectable muscle gain, fat loss, and quality of life. Harm reduction is crucial, mainly when the stigma and prejudice of medical professionals act as barriers to care. However, it's important to note that training hard puts the body under a lot of stress, so it's essential to give your body enough time to recover and rebuild. Overtraining is a real risk for bodybuilders and passion and commitment to training may sometimes be the thing that prevent progress. There are 14 carefully selected lab tests and panels listed below that are vital for maintaining health while boosting strength and body composition. What Tests are Included in the Bodybuilder Blood Test Panels? Complete Blood Count (CBC) A complete blood count (CBC) test panel measures immune cells, hemoglobin, the oxygen-carrying protein in red blood cells; hemoglobin concentration, the proportion of red blood cells to fluid in your blood (called hematocrit, which correlates with blood thickness); and platelets, which help in blood clotting. All androgens, including testosterone and AAS (polycythemia), raise the percentage of red blood cells (hematocrit), which affects blood thickness. High hematocrit can result in high blood pressure, headaches, and cardiovascular risks. This panel is essential because it indicates when your hematocrit reaches 53 and you need to donate blood or undergo therapeutic phlebotomy. Comprehensive Metabolic Panel (CMP) The complete metabolic panel (CMP panel), a preliminary medical screening tool for evaluating overall health, consists of 14 blood tests. The CMP blood test panel measures kidney, liver, glucose, electrolytes, and fluid balance levels. FASTING IS REQUIRED. Lipid Panel This panel has triglycerides, LDL (bad cholesterol), and HDL (good cholesterol) (fatty acids dissolved in the blood). Greater dosages of T and AAS can cause an increase in LDL while decreasing HDL and triglycerides. Cardiovascular issues may develop over time if HDL levels are significantly low. FASTING IS REQUIRED. EGFR and cystatin C kidney test Cystatin C is a more accurate method to evaluate renal function in people with higher muscle mass because growing muscle mass, consuming more protein, and supplementing with creatine can all change creatinine levels. Another measure of renal function is the estimated glomerular filtration rate (eGFR) and the cystatin C kidney test. The glomerular filtration rate is the rate at which fluid filters through the kidney. The creatinine clearance rate (CCRCr or CrCl), which measures the amount of blood plasma that is cleared of creatinine per unit of time, is a useful indicator of the estimated GFR. A low eGFR could indicate issues with renal function, as well as high levels of blood urea nitrogen (BUN). Accurate Liver (GGT) Test The GGT blood test looks for gamma-glutamyl transpeptidase (GGT), an enzyme or protein, in your blood. GGT is found in the liver's cells. This examination helps your doctor look for damage to the liver or the liver ducts. Alkaline phosphatase results, a separate blood test, can help distinguish between liver and bone diseases if they are abnormal. A test result that is higher than normal could be a sign of liver damage from cirrhosis, tumors, or pancreatic cancer, among other diseases. GGT is superior to liver enzymes included in the CMP, like AST and ALT, in that resistance training has no effect on its value, making it a more accurate method to diagnose liver disease in bodybuilders. Gold Standard: Total and Free Testosterone Tests Equilibrium ultrafiltration to determine free testosterone and liquid chromatography/mass spectrometry to determine total testosterone. Men with high testosterone levels cannot use the standard total testosterone test based on immunoassays since its upper limit is 1,500 ng/dL. Our testosterone test uses mass spectrometry, the most advanced and accurate testosterone test. Also, some laboratories offer computed free testosterone rather than the equilibrium ultrafiltration-based method we use, which is more accurate for this important number. Ultra-Sensitive Estradiol Testing (E2) The commonly used test may overstate estradiol. The combination of estradiol and C-Reactive Protein, which is associated with inflammation, is interpreted as estradiol by the immunoassay technique employed in that test because it is unable to differentiate between the two substances. This ultrasensitive estradiol test is based on the liquid chromatography/mass spectrometry (LC/MS) assay technique, which does not have that limitation. Furthermore, it has been demonstrated that DHT analogs like oxandrolone drastically suppress estradiol, which can lead to joint discomfort and other low estradiol issues. Interestingly, estradiol aromatization occurs in 0.4% of total testosterone. The body achieves balance by doing this to counteract the opposing effects of testosterone and estradiol on lipids. If your total testosterone is high, your estradiol will also be high. Use extreme caution when assuming that an aromatase inhibitor is necessary. For more information, please click on the effect of high and low estradiol on men's health. calculating estradiol using different testosterone dosages. Prolactin Test Many bodybuilders worry about elevated prolactin since it has been linked to erectile problems. DHT Test This test determines the amount of dihydrotestosterone (DHT) in the blood. High DHT has been linked to benign prostatic inflammation, acne, and hair loss in a small number of men. Low libido has been connected to decreased DHT. IGF-1 Test IGF-1 Test Human growth hormone levels in the blood are measured using the biomarker insulin-like growth factor 1, or IGF-1. It is a hormone that the liver and other organs produce and that affects processes supporting glucose metabolism and growth. Low IGF-1 may impede muscle growth. Ferritin Test A protein known as ferritin is where iron is kept. Iron is essential for the production of red blood cells and the distribution of oxygen throughout the body. Low amounts of ferritin cause anemia. TRT and anabolic steroids increase red blood cell production in the body (erythrocytosis). This increased production lowers ferritin levels and iron stores. Testosterone is known to cause ferritin levels to drop. Due to their high hematocrit (increased blood thickness from TRT and anabolics), men who use TRT and anabolics frequently donate blood or undergo therapeutic phlebotomy. Every donation causes a 30-point or more drop in ferritin. Low ferritin can cause fatigue, restless legs syndrome, muscle aches, and other issues. Get your bodybuilder test panel today! Bodybuilder Blood Test Guide: Are you a bodybuilder looking to keep track of your blood test results? A bodybuilder blood test can help monitor changes in hormone levels caused by the use of anabolic steroids and high doses of testosterone. But finding accurate and affordable tests can be challenging. Fortunately, DiscountedLabs offers comprehensive yet inexpensive lab tests for bodybuilders across the United States; no doctor’s visit is required. Get informed on how to prepare for a bodybuilder blood test, also known as bloodwork, and what results to expect with this helpful guide. What is a Bodybuilder Blood Test? A bodybuilder blood test is a series of tests that measure various aspects of health, such as hormone levels, cholesterol, and other markers. It can also measure the levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) in your blood, which is important for bodybuilders as high levels of cholesterol and triglycerides can increase the risk of heart disease and other health problems. The results of these tests can provide valuable insight into how to optimize your training and nutrition for better results. Overview of the Test A doctor or other healthcare professional typically orders and has a laboratory perform blood tests on bodybuilders. These tests measure different components in the blood, including hormones, electrolytes, enzymes, proteins, minerals, and vitamins. Depending on what type of test you get done, it will determine which specific biomarkers are tested for, especially if you are taking any dietary supplements. Benefits of the Test The primary benefit of getting a bodybuilder blood test is gaining insight into your overall health status, including general health, so you can make informed decisions about optimizing your diet and exercise routine for maximum gains in muscle mass and strength. Additionally, these tests can also reveal any potential deficiencies or imbalances that could be hindering progress toward achieving fitness goals. Finally, they may uncover any underlying medical issues that need further investigation from a physician before continuing with an intense workout program or taking certain supplements/medications without proper guidance from an expert healthcare professional first. Types of Tests Available How to Prepare for a Bodybuilder Blood Test? Pre-Test Instructions: Before taking a bodybuilder blood test, it is important to follow the instructions provided by your doctor or healthcare provider. These may include avoiding certain medications and supplements for a period of time before the test, as well as fasting for 8 to 12 hours prior to having your blood drawn. It is also important to inform your doctor about any recent illnesses or medical procedures you have had in order to ensure accurate results. Fasting Requirements: Fasting is an essential part of preparing for a bodybuilder blood test. This means not eating or drinking anything other than water for at least 8 hours before the test. During this time, it is best to avoid strenuous physical activity and alcohol consumption in order to get accurate results from the tests. The CMP test and the lipid panel require fasting for at least 8 hours. Certain medications can interfere with bodybuilder blood tests, so it is important to inform your doctor about all prescription and over-the-counter drugs you are taking before getting tested. Your doctor may recommend that you stop taking some medications temporarily while waiting for the results of your tests in order to ensure accuracy. Additionally, if you take vitamins or herbal supplements regularly, be sure to let your doctor know so they can advise whether these should be avoided prior to testing as well. Preparing for a bodybuilder blood test? Make sure to fast 8-12 hours, avoid strenuous activity & alcohol, and inform your doctor about any medications or supplements you take. #bodybuilding #bloodtest Click to Tweet Understanding the Results of a Bodybuilder Blood Test This type of test can help diagnose medical conditions related to hormone imbalances or deficiencies, as well as monitor progress during bodybuilding training. It’s important to understand what each component measures and how it affects your health before undergoing this type of testing. Common Abnormalities Detected in Tests: A bodybuilder blood test typically includes measurements for testosterone, estrogen, cortisol, thyroid-stimulating hormone (TSH), insulin-like growth factor 1 (IGF-1), albumin/globulin ratio (AGR), and luteinizing hormone (LH). High or low levels of any one of these components may indicate an underlying medical condition, such as hypogonadism or hyperthyroidism. Other abnormalities that may be detected, highlighting the critical role of these hormones in bodybuilding, include high cholesterol levels, elevated liver enzymes, abnormal red blood cell counts, or white blood cell counts. Interpreting Bodybuilder Test Results with Your Doctor: After receiving your results from a bodybuilder blood test, it’s important to discuss them with your doctor so they can explain what the numbers mean and if any further testing is needed. Depending on the results, you may need additional lab work to confirm a diagnosis or rule out certain conditions. Your doctor will also be able to recommend lifestyle changes or medications that can help improve your overall health, including heart health, based on the results of this type of testing. The Side Effects of Anabolic Steroids and High Doses of TRT on Bodybuilder Blood Test Results Anabolic steroids and high doses of testosterone can have serious effects on a person’s health, including their blood tests. It is important to understand the potential risks associated with anabolic steroid use or high doses of testosterone, as well as how it may affect your bodybuilder's blood test results. A. Potential Health Risks Associated with Anabolic Steroids and High Doses of Testosterone: Anabolic steroids are synthetic hormones that mimic the effects of testosterone in the body. Athletes and bodybuilders frequently use them to increase muscle mass, strength, and endurance, but they have a variety of negative side effects, including liver damage, heart issues, depression, aggression, infertility, and more. High doses of testosterone can also cause similar side effects as anabolic steroids but at a lesser degree due to its natural origin in the body. The use of anabolic steroids or high doses of testosterone can lead to changes in certain blood tests, such as increased levels of red blood cells (RBC), hemoglobin (Hb) and hematocrit (HCT). These changes could indicate underlying medical conditions such as polycythemia vera, which is caused by too many red blood cells being produced by the bone marrow, leading to thickening of the blood, increasing risk for stroke or heart attack if left untreated. White blood cell count (WBC) levels that drop can mean infection or inflammation; higher creatinine levels can mean kidney damage; higher cholesterol levels can raise the risk of heart disease; higher liver enzyme levels can mean liver toxicity; lower thyroid hormone production can lead to hypothyroidism; lower potassium levels can cause fatigue and other symptoms; and higher calcium levels can cause kidney stones and other problems related to an imbalance in calcium metabolism. These changes in blood tests serve as a baseline for understanding your general health and can also reveal potential health conditions that may interfere with your bodybuilding training and nutrition requirements. It is important that you discuss any abnormal results from your bodybuilder's lab test panel with your doctor so they can provide further guidance on what treatment options may be best suited for you depending on your individual situation. DiscountedLabs offers affordable lab testing without a doctor’s visit, so you can get tested regularly without breaking the bank. Where to Buy Affordable Bodybuilder Blood Tests from DiscountedLabs? DiscountedLabs is a great resource for bodybuilders looking to purchase affordable blood tests. DiscountedLabs offers a wide variety of lab tests, including those specifically designed for bodybuilders. These tests can help provide insight into the health and wellness of an individual, as well as their progress in achieving their fitness goals. DiscountedLabs provides convenient access to laboratory testing services without the need for a doctor’s visit or insurance coverage. They offer discounted rates on many types of lab tests, including those specifically designed for bodybuilders, such as hormone panels, cholesterol levels, liver function tests and more. In addition to providing discounts on these specific types of lab tests, they also offer additional services such as free shipping and 24/7 customer support via phone or email.   Bodybuilder Panels Sold by Discounted Labs: Bodybuilder Blood Test Panel- Basic Bodybuilder Blood Test Panel- Beginner Bodybuilder Blood Test Panel- Comprehensive   FAQs About Bodybuilder Blood Tests What blood tests do bodybuilders get? Bodybuilders typically get a variety of blood tests to monitor their health and performance. These include tests such as complete blood count (CBC), lipid panel, thyroid-stimulating hormone (TSH), testosterone, cortisol, iron levels, electrolytes, and energy levels. Higher levels of testosterone can also lead to increased energy levels, improved mood, and a higher sex drive, making it an important factor for bodybuilders to monitor. All these tests help bodybuilders assess their overall health status and determine if they are getting the proper nutrition for optimal muscle growth. Additionally, some bodybuilders may opt for additional specialized testing depending on their goals or medical history. Discounted Labs offers affordable lab testing in most cities across the U.S., allowing bodybuilders to easily access the necessary tests without having to visit a doctor’s office. What blood test do I need for steroids? The type of blood test you need for steroids depends on the specific steroid being used. Generally, tests are done to measure levels of testosterone, estradiol, and other hormones related to steroid use. Additionally, tests may be done to check for markers of liver damage or kidney function that can be affected by long-term steroid use. It is important to speak with a doctor before taking any form of steroids in order to determine which blood tests are necessary and how often they should be taken. Is there a blood test for muscle mass? Yes, there is a blood test for muscle mass. It's called the Creatinine Kinase (CK) test and it measures the amount of an enzyme in your bloodstream that is released when muscles are damaged or stressed. The CK test can help determine if you have too much or too little muscle mass, as well as provide insight into other health issues such as kidney damage or a heart attack. Results from this type of lab test are usually available within 1–7 business days after taking the sample. Discounted Labs offers affordable CK tests in most cities across the U.S., including measures of muscle tissue, so you don't need to visit a doctor's office to get tested. What is TRT blood work? TRT blood work is a type of lab test used to measure the levels of testosterone in the body. It is commonly used to diagnose and treat conditions related to low testosterone, such as hypogonadism or male infertility. The test measures both total and free testosterone levels, which can help determine if hormone replacement therapy, also known as testosterone replacement therapy, may be necessary. TRT blood work can also provide insight into other health issues that may be affecting overall well-being. Conclusion It is important for bodybuilders to monitor their blood tests regularly, especially if they are using anabolic steroids or high doses of testosterone. A bodybuilder's blood test can provide valuable insight into the health and wellness of a person's body. With DiscountedLabs, you can purchase affordable and reliable bodybuilder blood tests without having to visit a doctor's office. So don't wait any longer - get your bodybuilder blood test today.

Table of Contents What Is the Growth Hormone? Growth Hormone Functions and Effects Growth Hormone Synthesis and Control The Basics of Acquired Growth Hormone Deficiency in Adults Diagnosing Growth Hormone Deficiency Popular Clinical Features of Growth Hormone Deficiency in Adults Benefits of Growth Hormone Replacement Therapy Safety Considerations for Growth Hormone Therapy The Effects of Growth Hormone in People Who Are Not Deficient The Effects of Growth Hormone on HIV-Induced Cachexia The Effects of Growth Hormone on Athletes The Effects of Growth Hormone in Aging Patients Conclusions Get Your Growth Hormone Test and IGF-1 Test  1. Growth Hormone Test 2. Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) 3. IGF-1 (Insulin-like Growth Factor 1) Growth hormone deficiency is a health problem which can appear at birth or later on in life. It can affect adults and kids of all ages and has certain health consequences such as short stature in children, decreased muscle mass, low bone density, etc. This type of deficiency can be caused by various factors, including trauma, infection, radiation, or it could be genetic. This article takes a closer look at growth hormone deficiency as a medical condition. Keep reading to find out what influences it, how it can be treated, and what are the consequences when it gets too severe. What Is the Growth Hormone? Before learning more about growth hormone deficiency in adults, it’s necessary to understand what a growth hormone is. A growth hormone is a special type of protein which contains approximately 190 amino acids. This hormone is produced by the pituitary gland in the brain and it's necessary for the correct function of multiple processes in the body. For example, it's mainly responsible for bone growth, muscular development, maintaining healthy cholesterol levels, etc. When growth hormone is released by the pituitary, it travels through the bloodstream and binds to receptors in specific target cells. The human growth hormone is also responsible for the release of insulin-like growth factor 1 (IGF-1) by the liver. Growth Hormone Functions and Effects Human growth hormone has numerous effects on children and adults alike. Since this hormone is called the "growth hormone," one of its primary function is to stimulate the growth of bones, tendons, cartilages, and ligaments in kids until they become adults. Its mode of action is a slow and complicated process which involves the secretion of IGF-1 which stimulates chondrocytes. These are cartilage cells which start the growth of bones in children. The human growth hormone is also involved in the development of muscles in adults. This hormone stimulates myoblasts which are cells directly responsible for muscle growth. At the same time, growth hormone also has various metabolic effects. For example, it helps metabolizing macronutrients such as protein, fats, and carbohydrates. The administration of growth hormone can also stimulate the secretion of insulin in certain people. Growth Hormone Synthesis and Control Growth hormone is secreted by the anterior pituitary somatotrophs and it has various anabolic properties. The somatotropic cells amount for approximately 20% of the pituitary tissue and they can be inhibited by somatostatins which are produced by the hypothalamus. The hypothalamus is directly involved in the process of secreting the human growth hormone. For example, it emits the growth hormone-releasing hormone which kickstarts the production of growth hormone. The hypothalamus also secretes somatostatins to suppress this production when necessary. Other organs and tissues are involved in the production of growth hormone such as the liver, the gut, and the gonads. The human growth hormone is produced mainly at night in short pulses caused by the hypothalamus. This accounts for more than 85% of the total production of HGH. The release of growth hormone can be slightly increased through exercise. At the same time, it can be drastically decreased if the person in question is obese and sedentary. Ghrelin is also known as the “hunger hormone” and it can increase the production of growth hormone. This is a peptide created in the stomach which gives you the sensation of hunger. Ghrelin can bind to somatotrophs in the pituitary gland to increase the production of growth hormone. Having high levels of IGF-1 can also determine a reduction in the production of growth hormone. When these levels drop, Growth hormoneproduction is restored to normal parameters. You can measure the levels of IGF-1 in the bloodstream with a simple IGF-1 test. The Basics of Acquired Growth Hormone Deficiency in Adults A deficiency in the production of human growth hormone can be a severe health problem. This deficiency can be acquired through injuries to the hypothalamus, trauma, accidents, surgery, radiation, and more. Those who were treated for cancers in young adulthood using radiation are at a higher risk for developing a deficiency in growth hormone. Diagnosing Growth Hormone Deficiency A thorough examination is required to identify patients who are deficient in this hormone because the disease doesn’t have specific symptoms. Growth hormone therapy will be prescribed to those who have a severe deficiency of growth hormone. Some of the criteria which qualify a patient for growth hormone therapy include a history of damage to the pituitary or hypothalamus, a parasellar mass lesion, etc. The human growth hormone is generated in a pulsatile fashion, so just by doing a simple blood test to measure the levels of this hormone in the bloodstream is not enough. More investigations are necessary and this includes examinations of the pituitary gland. In some cases, the results can differ from patient to patient and that’s why establishing a correct diagnosis can be difficult. Further testing methods include injecting growth hormone-releasing hormone and arginine to determine if growth hormone is increased in individual patients. Popular Clinical Features of Growth Hormone Deficiency in Adults Severe cases of growth hormone deficiency in adults are usually associated with obesity, diabetes, a visible loss of muscle mass, and poor sleep quality. At the same time, these patients have increased cholesterol and triglyceride levels as well as hyperglycemia. Other clinical features popular with people who have growth hormone deficiency include decreased bone density. In fact, these people are more susceptible to have fractured bones, particularly later in life. A study performed on 40 patients with an average age of 44 years revealed that approximately 30% of them developed fractures in the following six years. Studies have also shown that people with decreased levels of growth hormone can develop an abnormal cardiac function as well as reduced exercise capacity and oxygen volume in the lungs. This means that the heart doesn’t work as it should and without treatment, growth hormone deficiency in adults can lead to more serious cardiovascular complications. Benefits of Growth Hormone Replacement Therapy Growth hormone replacement therapy is a viable option for deficient adults. This type of treatment is administered daily and it’s only prescribed to patients who have a certain and well-documented diagnosis given by the doctor. Patients need to take a GH test and come back for further examinations to determine if he/she really needs therapy or not. For example, the patient has serious pituitary problems and there are indications which reveal growth hormone deficiency started since childhood. Such a patient is a candidate for growth hormone therapy and the treatment can increase his quality of life. Although the results are varied, studies show that growth hormone therapy can help deficient patients have more energy when exercising. At the same time, this therapy has been shown to increase lean muscle mass and reduce fatigue. Safety Considerations for Growth Hormone Therapy As with any other treatment, growth hormone therapy is not without some risks. Although these can be minimized, each patient can experience different types of mild side effects. In some cases, growth hormone therapy can reveal the fact that the patient might have hypoadrenalism or hypothyroidism. These two conditions can drastically influence the results of growth hormone therapy in patients of all ages. Some of the side effects commonly associated with this type of treatment include muscle pain, swelling of the soft tissue in the body, sleep apnea, water retention, high glucose and hypertension. Studies show that approximately 30% of the patients will develop such side effects. Some of these secondary effects can appear over 5-10 years. Studies show that some patients who benefited from growth hormone therapy also had a high chance of developing a second neoplasm. This was more likely to happen for patients who had a childhood-onset growth hormone deficiency. At the same time, experiencing radiation to the neck or head during childhood might increase the chances of experiencing some of these side effects. Still, checking up with your doctor regularly to monitor your vitals can prevent or minimize side effects when undergoing growth hormone therapy. It’s important to keep your hormone under control during and after growth hormone replacement therapy. The Effects of Growth Hormone in People Who Are Not Deficient Some people are wondering if it’s ok to take growth hormone to increase athletic performance or simply to enhance the levels of IGF-1 in the bloodstream. Studies have been done on people who are not deficient in growth hormone. By doing a GH test, it has been discovered that this hormone has little to no effects on athletic performance, healing of fractures or osteoporosis. Therefore, healthy adults might not need to supplement with growth hormone unless they are deficient and have a well-documented medical history to prove it. The Effects of Growth Hormone on HIV-Induced Cachexia Cachexia is a medical condition characterized by a loss of muscle mass, appetite, and excessive fatigue in people who are not actively trying to lose weight. This health issue can be caused by multiple diseases and the most popular ones are cancer and HIV. Studies have been done on the effects of growth hormone in HIV-positive people who have cachexia. It has been shown that growth hormone therapy can help increase muscle mass while reducing fat. However, this type of hormone might not be recommended for people who are HIV-positive and also have diabetes since it can worsen glucose control. Administering a growth hormone-releasing hormone every day can reduce visceral and liver fat, improving the quality of life for the patient. The Effects of Growth Hormone on Athletes It is illegal for professional athletes to take supplements with growth hormone and participate in multiple types of sports. However, athletes have been used this hormone in significant quantities in the past. Although there are little to no clinical benefits demonstrated by the administration of growth hormone, some athletes experienced an increased fat-free body mass. This is one of the benefits of taking growth hormone supplements, but athletic performance, endurance, and stamina have not been shown to be positively influenced. A study performed on 96 athletes who took 2mg of growth hormone per day for eight weeks had similar results. Endurance, power, and muscle strength weren't affected. However, the sprinting performance was increased by a mere 6% and only in male participants. Another set of studies performed on a total of 303 athletes revealed that strength and exercise performance remained unchanged. These athletes took a high dose of growth hormone, which amounted to approximately 2.5mg daily. Almost half of these athletes developed side effects such as carpal tunnel syndrome, excessive sweating, and even edema. As a result, we can conclude that supplements with growth hormone are not useful for people who are not deficient in it. This hormone doesn’t increase athletic performance, endurance, strength, or stamina, which is contrary to popular belief. It can cause unwanted side effects, so it’s highly recommended to administer it only to growth hormone deficient patients. The Effects of Growth Hormone in Aging Patients Aging is a natural part of life, and it doesn’t come without its fair share of negative aspects. For example, people after 50-60 years start to experience various symptoms such as a predisposition for obesity, low energy levels, decreased muscle mass, and a tendency to store more fat. Sit has been theorized that growth hormone can be used to revitalize and rejuvenate people of an elderly age, especially seniors who are 60 years old or older. Studies performed on multiple healthy individuals revealed that a combination of growth hormone and testosterone could be used to increase muscle strength and stamina in seniors. This program basically consists of a mix of growth hormone therapy and testosterone replacement therapy. Other studies show that increasing the levels of IGF-1 can also slow down the aging process. Measuring the levels of this hormone can be done with a simple IGF-1 test. IGF-1 derives directly from the growth hormone, so by injecting growth hormone, the levels of IGF-1 in the bloodstream should also increase. IGF-1: Benefits and Risks Administering small doses of growth hormone in seniors might also enhance insulin sensitivity and offer protection against chronic illnesses which are specific to people of elderly age. Certain studies revealed that growth hormone therapy could add approximately ten years of life to some senior patients, so the benefits of this treatment cannot be ignored. However, there were also cases when excessive amounts of growth hormone administered to seniors can result in health complications. It has been discovered that too much growth hormone in the bloodstream can create a suitable environment for the development of colon polyps. Left untreated, these polyps can lead to fatal colon cancer. At the same time, excessive doses of growth hormone can also lead to the proliferation of breast cancer in certain patients. Experts suggest that growth hormone therapy should only be administered to deficient seniors who have well-documented cases of pituitary damage or hypothalamus injuries. A growth hormone therapy prescribed to healthy seniors can be detrimental to their health in the long run if not properly monitored. Conclusions Before administering growth hormone replacement therapy, a whole suite of tests and examinations should be performed on the patient. These tests should determine if the person in question has a pituitary problem or well-documented issues with the hypothalamus. If the patient had been deficient in growth hormone since childhood should also be taken into consideration. These tests are necessary to distinguish a patient who is deficient in growth hormone or if he has low levels due to aging. Get Your Growth Hormone Test and IGF-1 Test  It has never been easier than now to test how much growth hormone your body is producing or what are your real levels of IGF-1 in the bloodstream. You can do that simply and efficiently using direct-to-consumer blood tests. Visit DiscountedLabs.com and order an affordable growth hormone test for you or one of your family members. The procedure is simple - you order your GH test; download a lab request form to visit a nearby lab to draw blood, and you get your results by mail in a few business days. The whole process is quick, safe, and confidential. When you get your results, you can compare them against reference values or ask your healthcare provider to help you interpret them. Here are three popular tests you can order from DiscountedLabs today that are related to growth hormone. 1. Growth Hormone Test Growth hormone test provides a primary method to test growth hormone in the bloodstream. This hormone is released in a pulsatile and episodic fashion, having a half-life of approximately 25 minutes. The test should be performed on fasting individuals who were at rest for at least 30 minutes before drawing blood. Growth hormone blood test should be used in conjunction with other types of tests to determine if the individual has a deficiency or not. 2. Insulin-like Growth Factor-binding Protein 3 (IGFBP-3) IGF-1 is essential for a wide array of metabolic processes, as described earlier in this article. It’s also directly involved in muscle growth in adults. IGF-1 binds to a series of proteins, mainly to IGFBP-3. It binds to these proteins to safely circulate through the bloodstream. The iGFBP-3 protein helps to extend the half-life of growth hormone, and it must be available in correct levels in the bloodstream. This test measures the amount of IGFBP-3 in the blood. Patients should stop biotin supplementation 72 hours before doing the test. 3. IGF-1 (Insulin-like Growth Factor 1) The IGF-1 test is used to measure the levels of IGF-1 in the bloodstream. IGF-1 acts as a biomarker for the amount of growth hormone in the body. Use this test to determine the levels of IGF-1 in the body and find out if growth hormone is produced in sufficient quantities. These three tests give you a broader understanding of the levels of human growth hormone in the bloodstream. They're affordable, easy to do, and can be purchased online. Go to DiscountedLabs.com for more details!