Page 3 - Testosterone Blood Tests

Testosterone replacement therapy (TRT) is a medical treatment used to address low testosterone levels in men. Before initiating TRT, doctors conduct blood tests to measure total and free testosterone levels and evaluate symptoms such as low sex drive, erectile dysfunction, fatigue, low mood, and cognitive issues. Once TRT is underway, regular monitoring through blood tests is essential to ensure optimal outcomes and minimize potential side effects. This article explores the importance of blood tests in monitoring TRT, highlighting key values to consider for maximizing benefits and preventing complications. Table of Contents Blood Tests for Initial Assessment and Treatment Selection  Methods of Testosterone Replacement Therapy Follow-Up Blood Tests and Dosage Adjustments Monitoring Testosterone Levels Importance of Free Testosterone and Sex Hormone-Binding Globulin (SHBG) Monitoring Hematocrit Levels PSA Levels and Prostate Health Balancing Estradiol Levels Monitoring Blood Pressure Kidney Function (eGFR) Assessment Monitoring Liver Enzymes Thyroid Function Assessment Checking Iron Levels Monitoring HDL Cholesterol Levels Assessing Prolactin Levels Affordable Blood Testing Services and Additional Resources Conclusion Blood Tests for Initial Assessment and Treatment Selection Before initiating TRT, doctors rely on blood tests to assess testosterone levels and evaluate symptoms. Measuring total and free testosterone levels provides crucial information about hormone deficiencies. Additionally, asking patients about their symptoms helps identify possible signs of low testosterone. Based on these findings, doctors can determine the appropriate treatment approach for each individual.  Methods of Testosterone Replacement Therapy TRT can be administered using various methods, including injections, creams, gels, pellets, and nasal gels. The choice of method depends on factors such as patient preference, convenience, and specific medical considerations. The doctor's expertise is crucial in selecting the most suitable TRT option to ensure optimal results. Follow-Up Blood Tests and Dosage Adjustments Once TRT has commenced, regular follow-up blood tests are conducted around weeks six or eight. These tests help evaluate the effectiveness of the treatment and determine if any adjustments to dosage or additional medications are necessary. For instance, estradiol modulation may be required to maintain hormonal balance. Monitoring hormone levels through blood tests enables doctors to fine-tune treatment plans and ensure that patients receive the most beneficial outcomes from TRT. Monitoring Testosterone Levels Monitoring testosterone levels is a critical aspect of TRT. The target total testosterone level for men on TRT is typically above 500 nanograms per deciliter. If the measured level falls below this threshold, adjustments to dosage or injection frequency may be necessary to achieve optimal hormone balance. Importance of Free Testosterone and Sex Hormone-Binding Globulin (SHBG) Besides total testosterone, free testosterone levels are also significant. Free testosterone represents the portion of testosterone that is readily available for biological activity. Ideally, free testosterone should be around 2% of the total testosterone or higher. Lower levels may indicate issues related to sex hormone-binding globulin (SHBG), a protein that binds to testosterone and reduces its availability for use. Monitoring free testosterone levels helps doctors identify and address any SHBG-related concerns to optimize TRT outcomes. Monitoring Hematocrit Levels Hematocrit levels, which measure the proportion of red blood cells in the blood, should be monitored during TRT. Testosterone replacement can increase red blood cell count in some individuals. Elevated hematocrit levels can lead to increased blood viscosity and potential cardiovascular issues. To mitigate these risks, the ideal hematocrit range during TRT is below 53. Regular monitoring of hematocrit levels allows doctors to identify any concerns and take appropriate measures to maintain cardiovascular health. PSA Levels and Prostate Health Prostate-specific antigen (PSA) levels play a crucial role in monitoring prostate health during TRT. Men with a PSA level of four or higher require careful evaluation, as it may indicate prostate-related concerns, including the possibility of prostate cancer. Further investigation and consultation with a urologist are usually recommended for individuals with high PSA levels. Monitoring PSA levels is vital to ensuring the safe and effective administration of TRT. Balancing Estradiol Levels Estradiol, a form of estrogen, plays a significant role in men's health and well-being. Balancing estradiol levels is essential to maximizing the benefits of TRT. Very low or high estradiol levels can have negative effects on mood, cognition, cardiovascular health, sex drive, and body composition. The optimal range for estradiol levels provided by lab companies in men typically falls between 20 and 40 picograms per milliliter. However, this range does not apply to men with high testosterone blood levels caused by TRT. Regular monitoring of estradiol levels allows doctors to ensure hormonal balance and adjust treatment if necessary. Monitoring Blood Pressure Blood pressure monitoring is essential during TRT, as some men may experience increases in blood pressure due to hormonal changes. Lifestyle modifications such as weight loss, regular exercise, and medication can help manage blood pressure levels effectively. Regular blood pressure monitoring allows doctors to identify any changes and implement appropriate interventions to maintain cardiovascular health. Kidney Function (eGFR) Assessment Assessing kidney function is an important aspect of monitoring TRT. Estimated glomerular filtration rate (eGFR) is a measure used to evaluate kidney function. Contrary to common misconceptions, TRT itself does not cause a decrease in eGFR. Regular assessments of kidney function help ensure the safety and effectiveness of TRT by identifying any potential renal complications. Monitoring Liver Enzymes Liver enzyme levels, such as aspartate transaminase (AST) and alanine transaminase (ALT), should be monitored during TRT. It is important to note that TRT has not been shown to increase liver enzymes. However, men who engage in heavy weightlifting exercises may experience artificial increases in AST and ALT levels, which are unrelated to TRT or liver toxicity. Proper interpretation of liver enzyme levels is crucial to avoid unnecessary concerns or interventions. Thyroid Function Assessment Thyroid function should be monitored during TRT to ensure overall hormonal balance. Thyroid-stimulating hormone (TSH) levels are typically measured to evaluate thyroid function. A TSH level below 2.5 is indicative of a healthy thyroid. Further tests, such as measuring free triiodothyronine (T3) and free thyroxine (T4), may be conducted to assess thyroid function more comprehensively. Monitoring thyroid function allows doctors to address any thyroid-related issues that may impact TRT outcomes. Checking Iron Levels Regular monitoring of iron levels is important, particularly for individuals who frequently donate blood. Frequent blood donations can deplete iron stores, leading to fatigue and other related symptoms. To maintain optimal iron levels, individuals undergoing TRT should ensure that donation frequency aligns with recommended guidelines. If iron levels are found to be low, supplementation may be necessary to mitigate fatigue and maintain overall well-being. Monitoring HDL Cholesterol Levels High-density lipoprotein (HDL) cholesterol levels can be affected by TRT, especially at higher doses. Higher doses of testosterone replacement therapy may lead to a decrease in HDL cholesterol, which is a concern for cardiovascular health. Regular monitoring of lipid levels, including HDL cholesterol, allows doctors to assess cardiovascular risk and consider interventions such as niacin supplementation to manage HDL levels effectively. Assessing Prolactin Levels Prolactin levels are typically checked in men with very low testosterone levels or those who do not respond well to TRT. Elevated prolactin levels may indicate underlying issues that could impact the effectiveness of TRT. While prolactin is commonly associated with lactation in women, men also produce this hormone, and imbalances can lead to complications such as erectile dysfunction. Monitoring prolactin levels helps doctors ensure optimal treatment response for individuals undergoing TRT. Affordable Blood Testing Services and Additional Resources Discountedlabs.com offers affordable blood testing services, including the necessary tests for monitoring TRT labs. The website provides various blood test options, and results are typically delivered within five to seven business days. Additionally, Excel mail.com offers further information and resources on blood tests and TRT, including a blog page and a resources including a free downloadable book titled "Beyond Testosterome." These resources can help individuals educate themselves, better understand their blood test results, and make informed decisions about their TRT journey. Conclusion Monitoring TRT through regular blood tests is crucial for maximizing the benefits and preventing potential side effects. Key values to consider during blood tests include total and free testosterone levels, hematocrit levels, PSA levels, estradiol levels, blood pressure, kidney function, liver enzymes, thyroid function, iron levels, HDL cholesterol levels, and prolactin levels. Affordable blood testing services like Discountedlabs.com and resources from Excel mail.com provide individuals undergoing TRT with accessible options for monitoring their hormone levels effectively. Regular communication with healthcare professionals is vital to tailor TRT treatment and ensure its safety and efficacy. By monitoring key values through blood tests, individuals can optimize the benefits of TRT and enhance their overall well-being.            

Key Highlights Discover the importance of testosterone testing and its impact on men's health. Explore a curated selection of reputable online labs offering competitive prices. Learn insider tips to save money, including promotional codes and leveraging insurance. Find answers to frequently asked questions about testosterone testing and its significance. Understand the value of DiscountedLabs.com for affordable and convenient testing options. Get insights into interpreting your test results and discussing them with a healthcare provider. Introduction In men's health, knowing your testosterone levels is very important. A basic testosterone blood test, also known as the T test, measures this key sex hormone. It can give you helpful information about your overall health and well-being, and plays a crucial role in diagnosing and treating hormonal imbalances like low testosterone (male hypogonadism) and monitoring hormone replacement therapy, such as testosterone therapy. As men get older, testosterone levels often go down, which can cause health problems. This blog will introduce you to the importance of testosterone testing and the men’s health test price online. It will give you the knowledge you need to make good choices about your health with the guidance of a health care provider. Top Picks for Best Testosterone Test Prices Online Finding a cheap and trustworthy testosterone test is easier than you might expect. Many online labs now offer fair prices and easy testing options. These labs let you order tests online and then go to a nearby lab to give a sample. We will look at some of the best options for testosterone test prices online. We will think about things like cost, ease of use, and expert ratings. Also, we will share tips for finding a good and reliable provider for your testosterone testing needs. Where to Find the Best Prices for Testosterone Tests When you want to find the best testosterone test price online, it's important to compare prices from different labs. This means looking at the total costs, which includes the test price, shipping fees, and any extra charges. Good online labs usually share clear pricing information on their websites, making it easy to compare. Additionally, be sure to check if the lab offers a secure online portal for accessing your test results, as this can provide convenience and peace of mind. It is also important to consider the quality of the lab and their laboratory tests, as accurate and reliable results are crucial for making informed decisions about your health. Here are the prices for the "Testosterone, Free (Equilibrium Dialysis) and Total, MS" test from different labs: DiscountedLabs.com: $45.15 minus coupon: 10percentoff = $ 40.63 Ulta Lab Tests: $ 59 WalkinLabs: $68 PrivateMDLabs: $85   Keep in mind that just choosing the lab with the lowest price may not be the best way to go. Check for labs that are certified, follow privacy rules, and have good reviews from customers. 2. DiscountedLabs.com: Unbeatable Deals and Offers on Testosterone Tests DiscountedLabs.com is a leader in offering affordable testosterone tests. The website makes it easy for you to find and compare different testosterone test options and prices. They work with certified labs, so you can trust the accuracy of your test results. What makes DiscountedLabs.com unique is its focus on keeping costs low. The site often has special deals, discounts, and package offers, making it easier for more people to get testosterone tested. If you have a healthcare provider who uses a certain lab, DiscountedLabs.com can help you with that, too, so your testing is hassle-free. By focusing on convenience and low prices, DiscountedLabs.com helps people take charge of their health and understand their testosterone levels better. 3. Specialized Testosterone Test Packages for Varied Needs Understanding testosterone testing can feel confusing. But, many online labs now offer special test packages just for you. This personalized approach makes the testing easier and helps you get the right information. For example, if you worry about low testosterone, some labs provide packages that include a total testosterone test. These packages may also have other important hormone tests, like free testosterone and sex hormone-binding globulin (SHBG). Together, they give a better look at your hormone levels, including free testosterone levels. This helps healthcare providers make smart decisions and suggest the right treatments from specialized testing centers, such as specialty testing laboratories within the national network of primary clinical laboratories that perform regular quality assurance testing. 4. Insider Tips on Finding Promotional Codes and Discounts Saving money on testosterone tests is possible. Smart shoppers can use different ways to lower the costs of keeping track of their health. Here are some helpful tips to find promo codes and discounts for testosterone tests: Sign up for Lab Newsletters: Online labs often send exclusive deals and promo codes to their email subscribers. Follow on Social Media: Discounted Labs shares discounts and special offers on Facebook. Check Health Insurance: Sometimes, your health insurance might cover part or all of the cost of testosterone testing if it is needed for medical reasons. Using these money-saving tips can make testosterone testing easier. This way, you can focus on your health without spending too much. 5. Understanding the Value of Bundle Testing Options For people who want to keep track of their testosterone levels over a long period of time, bundling testing options using panels can save them money. Online labs usually give you lower prices when you buy several tests at once. This is especially helpful if you will need regular testosterone tests, like if you are on hormone replacement therapy. Here are other testosterone-related panels available on Discounted Labs: Testosterone (T+F), Estradiol and DHT Panel Testosterone (T+F), Hematocrit, Ultra Sensitive Estradiol and Prolactin Panel Testosterone (Total + Free), Ultrasensitive Estradiol & Hematocrit Testosterone + LH + FSH Panel Testosterone, Free (Equilibrium Dialysis) and Total, MS Testosterone, Free, Bioavailable and Total (With Lower & Upper Limit) plus SHBG Testosterone, SHBG, Hematocrit, Sensitive Estradiol and PSA Testosterone, Thyroid and Estradiol Panel Testosterone, Total ( LC/MS), Free T (Equilibrium Dialysis), Bioavailable T, and SHBG Testosterone, Total and Free (NO Upper Limit) plus Hematocrit Pre- TRT MALE Hormone / Wellness Panel TRT Basic Monitoring Panel TRT MALE Hormone/Wellness Follow Up Panel Buying in bulk (also called bundling) not only lowers the cost for each test but also makes it easier because you don’t have to place separate orders each time. It is a good option for people who want to stay on top of their health. But remember to check the expiration dates of the test kits when you buy in bulk. By thinking about your needs and the savings from bulk testing, you can make smart choices about how to manage your budget for testosterone monitoring. Why Testosterone Levels Matter for Men Testosterone is mostly known as the male sex hormone. However, it does much more than just impact sexual health. It also helps with muscle growth, bone density, mood, and brain function. For men of all ages, keeping testosterone levels healthy is key to overall well-being. When testosterone levels are off balance, it can cause various changes. These changes can be physical, emotional, or mental. It's important to recognize the signs and symptoms of low testosterone. This way, you can get medical help and look into possible treatments. The Critical Role of Testosterone in Male Health Testosterone is the main male sex hormone. It helps many important functions in a man's body. Besides its known role in sex drive and sperm production, testosterone also affects muscle mass, bone density, and red blood cell production. It is important to keep healthy testosterone levels. This helps with strong bones, better muscle growth and strength, and keeps energy levels up. Testosterone, a vital sex hormone in those assigned male at birth, is also a key hormone for mood, thinking, and heart health, as well as fat distribution in the body. In men, testosterone helps regulate sex drive and erectile function, muscle mass and strength, body fat distribution, bone density, and production of red blood cells and sperm. Low levels of testosterone or “low T,” may cause a variety of health challenges and changes to your overall health and physical appearance. As men get older, their testosterone levels drop. This can lead to lower sex drive, less muscle mass, and more tiredness. Understanding how testosterone affects male health is crucial. It shows why men should check their levels and get help from experts if there are any issues. Signs and Symptoms of Low Testosterone Levels Low testosterone, known as hypogonadism, can show up in different ways. It can affect your body and mind. Common signs include a lower sex drive, problems with erections, less muscle mass, and feeling more tired. Men with low testosterone might also see changes in their body, like more body fat and weaker bones. This condition can also affect feelings and thoughts, causing mood swings, irritability, trouble focusing, and sleep issues. It's important to notice these signs as possible signs of low testosterone. If you see any of these symptoms, it's good to talk to a healthcare professional about testing and treatment options. Long-Term Health Implications of Imbalanced Testosterone Maintaining balanced hormone levels is important for your health and well-being. Testosterone is the main male sex hormone. It plays a key role in many body functions. If its levels are too low, it can lead to serious long-term health problems. Low testosterone levels can increase the risk of health issues like heart disease, osteoporosis, type 2 diabetes, and metabolic syndrome. They can also lead to mood problems, sleep issues, and problems with thinking. Managing testosterone levels is important. Regular check-ups, changes in lifestyle, and the right medical help can lower the chances of these health issues. This can also improve your overall quality of life. Differences, Advantages, and Disadvantages of Different Testosterone Tests 1. At-Home Testosterone Kits   - Collection Method: At-home testosterone kits typically involve collecting a blood or saliva sample using a finger prick or saliva swab.   - Advantages:    - Convenience: At-home testosterone kits provide the convenience of testing testosterone levels from the comfort of your own home.    - Privacy: Some individuals may prefer the privacy of conducting the test at home.   - Disadvantages:     - Limited Accuracy: At-home testosterone kits may have limitations in terms of accuracy and reliability compared to tests conducted in a clinical setting.    - Lack of Professional Interpretation: Results from at-home kits may not come with professional interpretation, requiring individuals to seek medical advice for proper understanding and guidance. 2. Saliva Testosterone Test   - Collection Method: Saliva testosterone tests involve collecting a saliva sample using a swab or collection device.   - Advantages:    - Non-Invasive: Saliva testosterone tests are non-invasive and can be easily self-administered.    - Convenient: Saliva samples can be collected at any time and do not require a blood draw.   - Disadvantages:    - Limited Availability: Saliva testosterone tests may not be as widely available as blood tests.    - Potential Variability: Saliva testosterone levels may not always accurately reflect total testosterone levels in the blood. 3. LC/MS/MS Total Testosterone Test   - Collection Method: The LC/MS/MS (Liquid Chromatography-Mass Spectrometry) total testosterone test requires a blood sample typically collected from a vein in the arm.   - Advantages:    - High Accuracy: LC/MS/MS is considered a highly accurate method for measuring total testosterone levels.    - No Upper or Lower Limit: Unlike the immunoassay testosterone test, the LC/MS testosterone test is accurate at very low or very high testosterone blood levels.   - Widely Accepted: LC/MS/MS is a commonly used method in clinical settings for testosterone testing.   - No interference by supplements like biotin.   - Disadvantages:     - Requires a Blood Draw: Some individuals may find the process of having blood drawn uncomfortable or inconvenient.    - Laboratory Processing Time: Results from LC/MS/MS tests may take longer to obtain compared to rapid tests. 4. Immunoassay-Based Testosterone Test   - Collection Method: Immunoassay-based testosterone tests also require a blood sample, typically collected from a vein in the arm.   - Advantages:    - Rapid Results: Immunoassay-based tests can provide relatively quick results.    - Cost-Effective: Immunoassay-based tests are generally more cost-effective compared to LC/MS/MS tests .  - Disadvantages:    - Potential for Interference: Immunoassay-based tests may be susceptible to interference from certain substances or conditions, potentially affecting accuracy.    - Lower Sensitivity: Immunoassay-based tests may have lower sensitivity compared to LC/MS/MS tests. It is important to note that the choice of testosterone test should be made in consultation with a healthcare professional. They can guide you in selecting the most appropriate test based on your specific needs, medical history, and the accuracy and reliability of the available testing methods. How to Choose the Right Testosterone Test for You Choosing the right testosterone test depends on your needs and talking with a healthcare provider. Your medical history, symptoms, and the possible cause of hormonal issues are important in selecting the best test. A good first step is the total testosterone test. This test checks the total amount of testosterone in your blood. If the first results show any issues, a free testosterone test might be suggested. Free testosterone is the active part of the hormone that your body can use easily. Working together with your healthcare provider helps in picking a testosterone test. This way, you can get the best information to help with your health concerns. The Importance of Accuracy and Reliability in Test Results When you get testosterone tested, it is very important to have test results that are accurate and reliable. If the results are wrong, it can cause misdiagnoses, lead to bad treatment plans, and create unnecessary stress. You should pick testing providers that care about quality control. If you use at-home testing kits, carefully follow the instructions. Proper sample collection is key to reducing mistakes. Talk about any worries regarding test accuracy and reliability with your healthcare provider. They can help you understand your results and suggest trusted testing facilities, if necessary. Before You Buy: Understanding Testosterone Tests Beginning the journey of testosterone testing means you need to understand what these tests are and why they matter for men's health. Testosterone tests check the amount of testosterone in the blood. This hormone plays a key role in male sexual growth and function. Before getting a test, it is important to know the different types of testosterone tests. You should also understand what information they can provide and what things might affect test results. Deciphering Test Results: Free Testosterone vs. Total Testosterone Interpreting testosterone test results means knowing the difference between free testosterone and total testosterone. Total testosterone shows the overall amount of testosterone, while free testosterone shows the part that is active and works in the body. A normal range for total testosterone in adult males is usually between 300 and 1,000 nanograms per deciliter (ng/dL). This range can change a bit based on the lab. Free testosterone usually makes up about 2% of total testosterone. When looking at test results, it is important to think about both free and total testosterone levels. You should also consider your age, your overall health, and any symptoms you may have. A healthcare provider can help you understand your results and decide on the next steps. Preparing for Your Testosterone Test: Do's and Don'ts To get accurate and reliable testosterone test results, you need to follow certain preparation steps. These steps help reduce the effect of things outside your control that might change the results. Here’s a list of do's and don’ts to remember: Do's: Schedule the test for the morning. This is when testosterone levels are usually at their highest. Follow the fasting rules for testosterone testing. Breakfast can temporarily reduce testosterone levels, leading to misleading test results. Don'ts: Avoid heavy exercise. Hard workouts can raise testosterone levels for a short time. Don't drink alcohol. Alcohol can affect hormone levels and change the results. By following these tips, you can help ensure that your testosterone test shows the true state of your hormones. This will help you make better health choices. When to Consider Retesting: Timing and Frequency The time for testosterone testing depends on your situation and why you were first tested. If you had testing done to find a specific issue or to check how well treatment is working, your healthcare provider might suggest regular retesting. If your testosterone levels are normal and you have no major symptoms, you may not need to retest right away. Still, checking periodically is a good idea, especially as men get older. This helps keep track of any changes in hormones and can help catch issues early. Changes in your lifestyle, medications, or new symptoms could mean you need to test again. It's important to talk to your healthcare provider about a plan just for you. This way, you can take the best steps to keep your hormonal health in good shape. Interpreting Your Testosterone Test Results: A Comprehensive Guide Understanding testosterone test results involves looking at many factors that can affect hormone levels. It's important to talk to a healthcare provider for accurate reading and advice that suits you. Labs usually give a reference range for normal testosterone levels. These ranges might be a little different from one lab to another. Also, your personal situation plays a part in determining what levels are best for you. Factors such as age, overall health, medications, and any symptoms matter when thinking about what your results mean. It is important to note that test results are interpreted in the context of your specific health situation, and your doctor may recommend repeat testing or additional tests to learn more about what may be causing your symptoms and/or the change in your testosterone level and potential medical conditions, such as polycystic ovary syndrome (PCOS). Your healthcare provider will look at these factors along with your test results to check for any hormone issues. Next Steps: Managing Low or High Testosterone Levels Once you get your testosterone test results, what you do next depends on whether your levels are normal or not. If your levels are outside the normal range, your healthcare provider will suggest a plan made just for you. If you have low testosterone levels, testosterone replacement therapy (TRT) might be a good choice. TRT adds testosterone to your body using different methods like injections, gels, patches, or pellets. Sometimes, treating other health issues like obesity, diabetes, or thyroid problems can boost testosterone production. How to Find a Good Testosterone Doctor. Maximizing Savings on Testosterone Tests Taking care of your health doesn't have to cost a lot. There are many ways to save money on testosterone tests and still get good quality and accurate results. You can start by knowing what your insurance covers. You can also look into other testing choices. By taking charge of your testing costs, you can focus on your health while keeping an eye on your budget. Leveraging Health Insurance and HSA/FSA Accounts Maximizing your health insurance benefits and using tax-advantaged accounts like Health Savings Accounts (HSAs) or Flexible Spending Accounts (FSAs) can help you save money on testosterone testing. Before you have any tests done, check your health insurance policy or speak to your provider. This will help you find out if testosterone tests are covered. Some plans may cover everything for diagnostic reasons, while others might require you to pay part of the cost or meet a deductible. If you have an HSA or FSA, you can often use that money to pay for eligible costs, including testosterone testing. This can further lower your out-of-pocket expenses. By knowing how to use these financial tools well, you can make healthcare easier to access. Conclusion In conclusion, it is important to maintain balanced testosterone levels for the health and well-being of men. There are many online options for testosterone testing. You should look through them to find the best one for your needs. Keeping track of your test results can help you manage any imbalances effectively. When choosing a testosterone test provider, consider things like accuracy, reliability, and cost. By staying informed and active about your testosterone levels, you can improve your overall health. Start exploring the various testosterone testing options online for a better journey toward health. Frequently Asked Questions What is the average cost of a testosterone test online? The cost of a testosterone test online can change quite a bit. Usually, prices are between $49 and $200. This depends on the lab, the type of test, and any extra services offered. To understand the prices in your area better, it's a good idea to talk to your healthcare provider or look at online lab websites. How often should I check my testosterone levels? The amount of testosterone testing needed varies from person to person. It depends on your health and specific situation. Your healthcare provider can help you decide how often to get retested. They will consider things like your age, symptoms, and any health issues you may have. Can I trust the accuracy of online testosterone tests? The accuracy of online testosterone tests can change based on the provider and the type of test. Choose reliable online labs that work with certified labs and focus on quality. For extra comfort, talk about your test results with your healthcare provider. Are there any risks involved with testosterone testing? Testosterone testing is safe, whether you do it in a lab or with an at-home kit. There can be small risks, like bruising, bleeding, or infection, where the sample collection happens. These issues are rare and usually not serious. If you have any worries, talk to your healthcare provider.

Are you a bodybuilder looking to maximize your performance and ensure optimal health? Regular bodybuilding blood work is key to achieving these goals. It provides valuable insights into your body's functioning, allowing you to make informed decisions about your training, nutrition, and supplementation. In this blog, we will explore the importance of regular blood work for bodybuilders and how it can help you strike the right balance between performance and health. We'll also address common factors that can affect blood test values in bodybuilders, as well as essential lab tests that every bodybuilder should consider. Don't miss out on this valuable information that can take your bodybuilding journey to new heights. Table of Contents The Importance of Regular Bodybuilding Blood Work Maximizing Performance and Health: A Balance Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care Factors that Affect Blood Test Values in Bodybuilders Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Resistance Exercise Can Increase Liver Enzymes Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol High Doses of Anabolics Can Decrease Ferritin in Bodybuilders Understanding Essential Bodybuilding Blood Work Tests Complete Blood Count (CBC) Hematocrit Comprehensive Metabolic Panel (CMP) Lipid Test Panel Cystatin C with EGFR Kidney Test eGFR Kidney Test GGT Liver Test Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Free Testosterone (Equilibrium Ultrafiltration) Test Ultra-Sensitive Estradiol (E2) Test Prolactin Test DHT Test IGF-1 Test Ferritin Test How do these tests help optimize bodybuilding performance? The role of these tests in muscle gain, fat loss, and quality of life How can bodybuilders prepare for these tests? Why is regular bodybuilding blood work essential? How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com Conclusion   The Importance of Regular Bodybuilding Blood Work Regular bodybuilding blood work plays a crucial role in monitoring hormone levels and overall health, including high blood pressure. By conducting regular blood tests, bodybuilders can identify potential health issues before they become serious. Additionally, blood work provides valuable insights for optimizing nutrition and supplementation, leading to better performance. Tracking blood markers allows bodybuilders to make informed decisions about their training and recovery strategies. Ultimately, regular blood work is essential for long-term health and longevity in the world of bodybuilding. By staying on top of blood markers like testosterone, hormone levels, glucose, and kidney function, bodybuilders can ensure they are in optimal condition to achieve their goals. Maximizing Performance and Health: A Balance Regular monitoring of bodybuilding blood work, including testosterone tests, is crucial for bodybuilders to maximize their performance and maintain good health. Through regular blood tests, bodybuilders can monitor hormone levels, nutrient deficiencies, and overall organ function. This information is invaluable in making informed adjustments to diet, supplements, and training routines. By maintaining a balance between performance and health, bodybuilders can optimize their training and achieve their goals. Prioritizing health through regular blood work is essential for long-term success and sustainable progress in bodybuilding. It allows bodybuilders to identify any potential imbalances and make the necessary adjustments for optimal performance. By utilizing comprehensive metabolic panels, lipid panels, and hormone level tests, bodybuilders can ensure that their training is effective and their bodies are functioning optimally. Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses   According to a scientific review, the use of anabolic steroids has the following ergogenic effects: ■ Increase in lean body mass ■ Increase in muscle cross-sectional area ■ Decrease in body fat percent ■ Increase muscle strength & power ■ Enhance recovery between workouts ■ Enhance recovery from injury ■ Increase in protein synthesis ■ Increase in muscle endurance ■ Increase in erythropoiesis, hemoglobin, and hematocrit ■ Increase in bone mineral density ■ Increase in glycogen storage ■ Increase in lipolysis ■ Increase in neural transmission ■ Reduced muscle damage ■ Increase in pain tolerance   However, the use of these agents could have the following side effects: Cardiovascular ■ Lipid profile changes ■ Elevated blood pressure ■ Decreased myocardial function Increased in blood viscosity due to high hematocrit Dermatological ■ Acne ■ Male pattern baldness Endocrine ■ Gynecomastia ■ Decreased sperm count ■ Testicular atrophy ■ Impotence and transient infertility Hepatic ■ Increased liver enzymes Renal Decreased kidney function Genitourinary Males ■ Reduced sperm counts ■ Decreased testicular size Females ■ Menstrual irregularities ■ Clitoromegaly ■ Masculinization Males and Females ■ Gynecomastia ■ Libido changes Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care The stigma surrounding performance-enhancing drugs (PEDs) frequently makes bodybuilders reluctant to seek medical attention. Many bodybuilders are reluctant to disclose their PED use due to fear of judgment or a lack of understanding from healthcare professionals. This can impede their access to important resources such as regular blood work, which is vital for monitoring health and performance. Healthcare professionals need to be knowledgeable about the potential risks and side effects associated with PEDs in order to provide appropriate care and guidance. Open communication and support between bodybuilders and healthcare professionals can foster collaboration for optimizing performance while minimizing health risks.   Factors that Affect Blood Test Values in Bodybuilders Muscle damage and inflammation can impact blood test results in bodybuilders, as the body's response to intense training can cause temporary changes in certain blood markers. Additionally, high protein intake, which is common among bodybuilders, may affect kidney function and liver enzymes but is not clinically significant, which is concerning to doctors not familiar with this fact. Steroid use can also lead to hormonal imbalances and abnormal blood test results. Dehydration, which can occur during intense workouts or when bodybuilders are cutting weight, can cause changes in electrolyte and blood cell levels. Weight training can also increase certain live enzymes in a non-clinical way. Supplements like creatine can falsely increase serum creatinine, which can alarm certain physicians. It is important for bodybuilders to address any nutritional deficiencies identified through blood testing, as these deficiencies can impact performance and overall health. Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Anabolic steroid use without testosterone can result in a decline in testosterone levels among bodybuilders, leading to low testosterone, or TSH. Testosterone plays a crucial role in muscle growth, recovery, and overall performance in bodybuilding. To ensure optimal health and performance, bodybuilders should regularly monitor their testosterone levels. Consulting with a healthcare professional can help them effectively manage their hormone levels. It is essential to maintain balanced testosterone levels to avoid negative side effects and maximize results. By being proactive in monitoring testosterone levels, bodybuilders can optimize their performance and achieve their desired outcomes. Resistance Exercise Can Increase Liver Enzymes Intense resistance exercise can result in temporary elevations in liver enzymes, including alkaline phosphatase, which is a normal response to muscle damage and repair. It is crucial for bodybuilders to inform their healthcare provider about their exercise routine before getting blood work done. Although elevated liver enzymes due to exercise are typically harmless and resolve on their own, regular monitoring of liver enzymes is essential for bodybuilders to ensure optimal health and performance. By keeping track of liver enzyme levels, bodybuilders can identify any abnormalities early on and take appropriate actions to maintain their liver function. Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Creatine supplementation can temporarily decrease kidney function markers, leading to lower creatinine and potassium levels in bodybuilders. It is important for bodybuilders to inform their healthcare providers about any dietary supplements before undergoing blood tests. Once creatine supplementation is discontinued, creatinine and potassium levels can normalize. However, monitoring kidney function through multiple biomarkers is essential for an accurate assessment. By incorporating these measures, bodybuilders can ensure that their kidney function is accurately evaluated. Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol Certain oral anabolic steroids used by bodybuilders have the potential to increase liver enzymes and decrease HDL cholesterol levels, leading to an increase in total cholesterol and low-density lipoprotein. Regular blood tests are vital for bodybuilders who use these oral steroids to monitor their impact on liver function and cholesterol levels. Elevations in liver enzymes can be a sign of liver damage, while decreased HDL cholesterol levels pose a risk for cardiovascular health. Working with a healthcare professional is essential to mitigating these potential risks associated with the use of oral anabolic steroids. By closely monitoring liver health and cholesterol levels, bodybuilders can make informed decisions about their supplementation and take necessary steps to protect their overall health. High Doses of Anabolics Can Decrease Ferritin in Bodybuilders High doses of anabolic steroids can result in decreased ferritin levels among bodybuilders, impacting their overall performance. Ferritin plays a crucial role as a protein that stores iron, and deficiencies can have negative effects on muscle growth and health. To optimize supplementation and monitor ferritin levels, regular blood tests are essential. Consulting with a healthcare professional can provide personalized guidance on maintaining optimal ferritin levels and growth hormone levels. It is important for bodybuilders to be aware of the potential impact of high doses of anabolic steroids on ferritin levels and take proactive measures to ensure balanced hormone levels and nutrition. By prioritizing the monitoring of ferritin levels, bodybuilders can support their muscle growth and overall well-being. Understanding Essential Bodybuilding Blood Work Tests Regular blood work is vital for bodybuilders to monitor their health and optimize their performance. Key lab tests for bodybuilders include hormone levels, liver function, kidney function, and thyroid function. These tests can help identify potential health issues and allow for adjustments in training and nutrition plans. Working with a healthcare professional who specializes in sports medicine or bodybuilding is beneficial to ensure an accurate interpretation of the results. By regularly monitoring hormone levels, such as testosterone and estradiol, bodybuilders can address any imbalances and make necessary adjustments to their supplementation or hormone replacement therapy. Additionally, liver function tests like ALT and AST can assist in identifying any liver abnormalities or damage that may result from the use of anabolic steroids. Kidney function tests, like creatinine and BUN, are crucial for assessing the impact of intense training and supplement use on the kidneys. These lab tests provide valuable insights into a bodybuilder's health and play a crucial role in maintaining optimal performance, including CMP. Complete Blood Count (CBC) A complete blood count (CBC) test panel measures several components of your blood, including Red blood cells, which carry oxygen, White blood cells, which fight infection; hemoglobin, the oxygen-carrying protein in red blood cells; hematocrit, the proportion of red blood cells to the fluid component in your blood (which is correlated with blood thickness); and Platelets, which help with blood clotting. Hematocrit All androgens, like testosterone and AAS, can increase red blood cells and their proportion in the blood (hematocrit), increasing blood thickness (erythrocytosis). High hematocrit can cause high blood pressure, headaches, and cardiovascular risks. This panel is essential since it determines when you reach a hematocrit of 53, indicating that blood donation or therapeutic phlebotomy is needed. Comprehensive Metabolic Panel (CMP) The comprehensive metabolic panel, or CMP panel, consists of 14 blood tests that are an initial medical screening tool to review overall health. The CMP blood test panel checks for glucose, kidney function, liver function, electrolytes, and fluid balance. Fasting IS REQUIRED. Lipid Test Panel This panel includes LDL (bad cholesterol), HDL (good cholesterol), and triglycerides (fatty acids dissolved in the blood). Higher doses of T and AAS can increase LDL and decrease HDL and triglycerides. Severely decreased HDL may cause cardiovascular issues in the long term. FASTING IS REQUIRED. Cystatin C with EGFR Kidney Test Since higher muscle mass, protein intake, and creatine supplementation can all affect creatinine as the primary variable, cystatin C is a more accurate way to assess kidney function in people with higher muscle mass. Another one of the measures of kidney function is the estimated glomerular filtration rate (eGFR). The glomerular filtration rate describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCRCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit of time and is a useful measure for approximating the GFR. eGFR under 60 may indicate issues that are affecting kidney function. eGFR Kidney Test The eGFR kidney test is an important tool for bodybuilders to monitor their kidney health and ensure optimal performance. By measuring how well the kidneys are functioning, this test can help detect any potential kidney issues that may arise, affecting metabolism. It is crucial for bodybuilders to regularly check their eGFR levels, as low levels under 60 can indicate kidney damage or impaired kidney function, which can have a negative impact on performance. Maintaining a healthy eGFR level is essential for overall health and athletic performance. Consulting with a healthcare professional is recommended for interpreting eGFR results and taking the necessary steps to support kidney health. GGT Liver Test The GGT blood test looks for an enzyme, or protein, called gamma-glutamyl transpeptidase (GGT) in your blood. GGT is found in liver cells. This test helps your doctor look for damage to your liver or its ducts. It can also help tell the difference between liver and bone disease if your results from a different blood test called alkaline phosphatase are abnormal. Higher than-average test results could indicate liver damage from diseases such as hepatitis, cirrhosis, tumors, or pancreatic cancer. The good thing about GGT (unlike liver enzymes included in the CMP like AST and ALT) is that resistance exercise does not affect its value, so it is a more accurate way to detect liver disease in bodybuilders. Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Men with high testosterone cannot use the regular total testosterone test based on immunoassays since it has an upper limit of 1,500 ng/dL. The LC/MS testosterone test does not have an upper limit. Also, some labs offer calculated free testosterone instead of the equilibrium ultrafiltration-based one, which is more accurate for this critical variable. Free Testosterone (Equilibrium Ultrafiltration) Test The equilibrium ultrafiltration test is a precise method used to measure the amount of unbound testosterone in the bloodstream. Free testosterone plays a crucial role in muscle growth, strength, and overall performance for bodybuilders. Monitoring free testosterone levels can provide valuable insights into potential imbalances or deficiencies that may impact training, recovery, and hormone balance. By regularly testing free testosterone, bodybuilders can optimize their training and supplement plans to maximize their performance and health. This test, along with other essential lab tests, helps bodybuilders maintain optimal hormone levels and ensure their body is functioning at its best. Ultra-Sensitive Estradiol (E2) Test The commonly used estradiol test may overestimate estradiol. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This ultrasensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation. Furthermore, DHT analogs like oxandrolone may dramatically decrease estradiol, causing joint aches and other low estradiol issues. Note: 0.4 percent of total testosterone aromatizes to estradiol. This is the body's way of balancing testosterone's negative effect on lipids with estradiol's beneficial effect. If your total testosterone is high, so is your estradiol. Be very careful in assuming that an aromatase inhibitor is needed. For more information, click on the effect of high and low estradiol on men's health. How to predict estradiol for different testosterone doses. Prolactin Test Many bodybuilders worry about increased prolactin since it has been associated with erectile dysfunction. Regular monitoring of hormone levels is essential for bodybuilders, and the prolactin test plays a crucial role in this process. This test helps detect potential imbalances that can impact performance and overall health. Elevated prolactin levels may indicate issues such as reduced testosterone production or the presence of pituitary gland tumors. Therefore, it is vital for bodybuilders to undergo regular prolactin testing to optimize their performance and maintain their overall well-being. However, interpreting the results accurately requires consultation with healthcare professionals. By keeping prolactin levels in the optimal range, bodybuilders can enhance muscle growth, support recovery, and promote their overall physical and mental well-being. DHT Test This test measures the amount of dihydrotestosterone (DHT) in the blood. Low DHT has been associated with low libido, and high DHT has been linked to acne, hair loss, and benign prostatic inflammation in a minority of men. DHT test (LC/MS) measures dihydrotestosterone levels, a hormone linked to muscle growth and male characteristics. It helps bodybuilders evaluate hormonal balance for enhanced performance. Monitoring DHT levels provides insights into potential side effects or risks associated with supplements or steroid use. Regular testing tracks progress and informs decisions on training and supplementation. Discussing results with healthcare professionals creates personalized strategies for goals. IGF-1 Test Insulin-like Growth Factor 1, also known as IGF-1, is used as a biomarker for blood levels of human growth hormone. It is a hormone that the liver and other tissues produce that affects glucose metabolism and growth-promoting activities. Low IGF-1 may impede muscle growth. The IGF-1 test, performed using LC/MS, is a crucial tool for bodybuilders to assess their performance and overall health. This test measures the levels of insulin-like growth factor-1, a hormone that plays a vital role in muscle growth and repair. By analyzing IGF-1 levels, bodybuilders can determine whether they have optimal hormone levels for performance and recovery. Low levels of IGF-1 may indicate potential limitations in muscle growth or underlying health issues. Ferritin Test Ferritin is a protein that stores iron. Red blood cells need iron to form and carry oxygen around your body. Low levels of ferritin lead to anemia. TRT and anabolic steroids make the body make more red blood cells (erythrocytosis). This increased production decreases iron stores and ferritin. Testosterone has been shown to decrease ferritin. Men who use TRT and anabolic steroids and have high hematocrit (increased blood thickness due to TRT or anabolic steroids) frequently donate blood or undergo therapeutic phlebotomy to lower hematocrit. There is a loss of around 30 points of ferritin during every donation. Low ferritin can cause fatigue, restless leg syndrome, muscle aches, and other issues. How do these tests help optimize bodybuilding performance? Bloodwork tests play a crucial role in optimizing bodybuilding performance. They provide valuable insights into hormone levels, nutrient deficiencies, and overall health. By identifying imbalances or deficiencies, bodybuilders can make targeted adjustments to their diet and supplementation, enhancing muscle growth, recovery, and overall performance. Regular blood work helps track progress and make necessary adjustments to training and nutrition protocols. The role of these tests in muscle gain, fat loss, and quality of life Blood tests play a vital role in bodybuilding, specifically when it comes to muscle gain, fat loss, and overall quality of life. These tests provide valuable insights into hormone levels, such as testosterone and cortisol, which are crucial for optimal muscle growth and fat loss. By monitoring these blood markers, bodybuilders can optimize their recovery and prevent overtraining. Additionally, blood work can reveal any nutrient deficiencies that may be hindering progress in muscle gain or fat loss. Moreover, assessing liver and kidney function through blood tests ensures the overall health and longevity of bodybuilders. Regular blood work is essential for identifying potential health risks and allowing for timely intervention to maintain a high quality of life. How can bodybuilders prepare for these tests? To prepare for bodybuilding blood work, it's important for bodybuilders to stay hydrated, avoid strenuous exercise or heavy lifting 48 hours before the test, follow any fasting requirements given by the healthcare provider, and inform them about any supplements or medications being taken. Why is regular bodybuilding blood work essential? Regular monitoring of crucial parameters is essential for bodybuilders. It helps ensure optimal performance and overall health. By tracking hormone levels, liver function, and kidney function, bodybuilders can make informed decisions about their training, nutrition, and supplementation strategies. Regular blood work also provides a baseline for comparison and allows assessment of the effectiveness of lifestyle choices on health and performance. How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com To buy affordable bodybuilder blood work on DiscountedLabs.com, simply visit the website and create an account. Then, search for the specific bodybuilder blood work panel you need and add it to your cart. Proceed to checkout and apply any available discount codes before completing your purchase. Bodybuilder Panels Sold by DiscountedLabs.com Bodybuilder Blood Test Panel- Basic Bodybuilder Blood Test Panel- Beginner Bodybuilder Blood Test Panel- Comprehensive Conclusion Regular bodybuilding blood work is essential for maximizing performance and maintaining good health. It helps bodybuilders identify any imbalances or potential health risks caused by their training regimen and performance-enhancing agents. Understanding the importance of these tests and regularly monitoring key parameters such as testosterone levels, kidney function, liver enzymes, and lipid profiles can help bodybuilders optimize their muscle gain, fat loss, and overall quality of life. To ensure accurate results, it is important for bodybuilders to prepare for these tests by following specific guidelines. Regular monitoring of these parameters allows bodybuilders to make adjustments to their training and nutrition plans, minimizing potential risks and improving long-term outcomes. DiscountedLabs.com offers affordable bodybuilder blood work, making it easier for individuals to access these crucial tests. Take charge of your bodybuilding journey and prioritize your health and performance with regular blood work.        

Welcome to DiscountedLabs.com, where you can buy discount lab tests in most cities in the U.S. (except in the states of NY, NJ, AZ, MS, and RI). No doctor visit is required. We invite you to compare our prices with those of other lab companies so that you can see how we are different from the rest. At DiscountedLabs.com we believe that knowledge is power. Educated patients can take charge of their health and discuss health issues more effectively with their physicians. Many people find our prices lower than their insurance co-pays for lab tests. Not having a copay to see a doctor provides additional benefits for the educated patient. These educated patients have also realized that their insurance companies are unwilling to pay for specific tests and/or the required frequency for proper monitoring. That is where DiscountedLabs comes in to provide affordable online blood test access. The order process for discounted labs is simple: use a credit card. Just choose your blood test and order it. You will receive a confirmation email with a lab form that you can take to your closest lab location. This location can be searched in the page tab entitled “Find a location”. Please bring the confirmation receipt email and ID to the local lab of your choice in our network. You will receive your lab results a few days later via email.     HOW DOES DISCOUNTEDLABS.COM WORK?   1-     Go to the "Find a Location" page to make sure we serve your state and that there is a location near you.  2-     Go to "Choose a Test" and add your selection (s) in the shopping cart. You can also save money by buying bundled lab test panels. 3-     If you have a discount coupon code, add it to your cart. 4-     If you don't have an account with us, you will be asked to create one by adding your name, address, gender, and date of birth. 5-     Place your order by using a credit card. 6-     You will receive three emails: an order confirmation & detailed instructions within minutes about how to download your lab requisition form to take to the lab near you. 7-     Print the lab requisition form (PDF file).  8-     Take that form to the lab near you with a picture ID. You can walk in, but we suggest that you make an appointment to cut down on potential waiting (instructions on how to do so are in our "Find a Location" page). Get your blood drawn at the lab.   9-    Your results will be ready within 3-7 business days, depending on the test. Sensitive hormone tests done by liquid chromatography/mass spectrometry LC/MS take 5-7 business days). You will receive them by email as soon as they come in. If you have any questions, please visit our FAQ page or email us at [email protected] Why DiscountedLabs.com? We Have the Best Discount Lab Tests Available in the U.S. No Doctor Visit. Prescription Provided. Most U.S. States. No Hidden Costs. FDA Approved. HIPAA Compliant. We Protect Your Privacy. Order Good for 9 Months. No Appointment Needed. Walk-ins Welcomed. Results Delivered By Email. Hormone Testing Via Sensitive Assays. Discount Coupons Emailed Periodically. Educational Videos Thank you, and tell your friends about us!   At DiscountedLabs.com we pride ourselves on offering the most affordable blood test prices and educational information to help you take charge of your health. You can purchase blood tests and panels online from most cities in the U.S. using your credit card. Our in-house physician provides the required prescription, so no doctor’s visit is needed. Depending on the blood test, you can download your results from your account in 2-7 business days (depending on the blood test) after your blood draw at your local lab. We work with over 1,800 lab locations. No appointment is needed at the lab. Walk-ins welcomed. We provide educational information in our blog and newsletters so that you can make sense of your results. Your order is good for six months, so you can have time to plan. Your order is secure and private. 100% satisfaction guarantee. Patients like you founded us with the intention of facilitating easy access to health self-monitoring.    

A brief introduction to testosterone and its properties and benefits Testosterone is the most important male sex hormone responsible for correctly functioning multiple body processes. This anabolic steroid is directly involved in developing reproductive organs in men and developing secondary male sexual characteristics. Testosterone plays a vital role in the lives of women, too. Inadequate testosterone amounts can lead to numerous health issues, such as low bone density (and susceptibility to fractures), poor sex drive, and lack of concentration. Table of Contents A brief introduction to testosterone and its properties/benefits What is hypogonadism?   Serum testosterone tests (assays) Types of testosterone fractions in the blood Types of testosterone tests How is testosterone level measured? Dr. Wang's analysis of testosterone assays 4 Types Of Testosterone Tests You Can Buy Today Why should you test your testosterone levels? How to get a testosterone test? Normal testosterone levels in men are between 300 ng/dL and 1,000 ng/dL. Normal testosterone levels in women are usually between 15 ng/dL and 70 ng/dL. This number varies depending on various factors such as the moment of the day, mood, diet, exercise level, and more. However, certain men might have low testosterone levels (under 350 ng/dL) and experience symptoms such as fatigue, lack of sexual desire, and developing male breasts (gynecomastia). Testosterone replacement therapy might be helpful for men who have low testosterone blood levels. This treatment will help raise testosterone levels to average values. Inadequate testosterone amounts can also impair muscle development and slow one’s progress in the gym. Men usually have 40 times more testosterone than women, and keeping T levels in the normal range is essential to ensuring proper muscle growth. Declining testosterone levels in men over 45 are typical and often cause erectile dysfunction (ED). Androgen deficiency, or hypogonadism, affects roughly 40% of men aged 45 or older.  Two-thirds of these men present with symptoms. While some symptoms, like ED, indicate a deficiency, additional symptoms can be similar to those of other diseases, such as cardiovascular disease.  What is hypogonadism?   Male hypogonadism is a clinical syndrome that results from the failure of the testes to produce physiological levels of testosterone (androgen deficiency) and an average number of spermatozoa due to disruption of one or more groups of the hypothalamic-pituitary-testicular (HPT) axis. There are three types of hypogonadism: Primary-testicular dysfunction leads to low testosterone levels and high levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Secondary dysfunction of the HPT axis results in low testosterone, LH, and FSH levels. Who should be tested for low testosterone? Mixed—manifests a mixture of primary and secondary hypogonadism and can be observed in older men. Very small or shrinking testes. Inability to father children; low or zero sperm count. The more symptoms a patient has, the more likely he is to have low testosterone.    The production of androgens in excess is a defining feature of hyperandrogenism (high testosterone in women), and testosterone levels have an impact on it. The most common clinical manifestation of hyperandrogenism is hirsutism, or excessive hair growth in androgen-dependent body areas. Other clinical manifestations of hyperandrogenism include acne vulgaris, weight gain, menstrual irregularities, and, in some women, polycystic ovary syndrome (PCOS) and acanthosis nigricans. Measuring the testosterone level isn’t an easy task. Tests for free, bioavailable, and total testosterone are essential to help diagnose hypogonadism and rule out other conditions. For those who may be candidates for testosterone therapy and those already on treatment, testing can also help assess and monitor testosterone levels.   This hormone can be bound to specific proteins in the body, and measuring it becomes problematic when it’s outside the normal ranges. For example, it’s relatively easy to determine the exact testosterone level of a healthy man, but not that easy if he’s hypogonadal (has low T) and his testosterone levels are dangerously low. More sensitive tests are required to measure low T concentrations in men, women, and prepuberty children. Scientists and medical professionals have created some reliable testosterone-measuring methods. These are called testosterone assays.   Serum testosterone tests (assays) According to the dictionary, the word “assay” refers to testing a particular material, ore, or substance to find its composting ingredients. Serum testosterone assay refers to accurately measuring the testosterone levels in the body of a male or female. Accuracy is essential because it directly impacts the diagnosing a particular disease or health complication. Endocrinology is the discipline responsible for measuring hormone levels in the body. It encompasses a wide variety of assays that help the clinician confirm a diagnosis for a patient. For example, testosterone assays are used to determine whether a male patient has hypogonadism. Hypogonadism consists of reduced gonad activity. Men diagnosed with hypogonadism usually have low testosterone levels and experience different symptoms, such as low sex drive and gynecomastia (man boobs). Testosterone assays are also used to determine if confident boys have delayed puberty onset and to diagnose androgen deficiency. When circulating testosterone levels are very low, the sensitivity of some assays is diminished. That’s why picking the suitable testosterone assay is necessary to determine circulating T levels accurately.   Types of testosterone fractions in the blood As shown in the figure below, about 2 percent of the testosterone in the body is active.  This “free testosterone” is not attached to binding proteins that would prevent it from interacting with its receptor. About 40 percent of the body’s testosterone is attached to albumin. This is a protein that can release the hormone as the need for it arises in the body. Free testosterone and testosterone bound to albumin are “bioavailable testosterone.” In a healthy young male, about 60 percent of his testosterone is attached to sex hormone-binding globulin (SHBG). Hormones bound to SHBG can’t be used by the body and lose their anabolic effect.  As males grow older or if an illness is present, SHBG sweeps up more and more testosterone, lowering free testosterone and its benefits. Total testosterone is the sum of bioavailable testosterone and testosterone bound to SHBG. Measuring the total testosterone in the blood may not provide the whole picture and let you know how much “active” or usable testosterone you have. Types of testosterone tests Measuring the testosterone levels in one’s body is not that easy. One way to do that is by using Isotope dilution mass spectrometry. This assay measures total testosterone levels. Laboratories also use direct chemiluminescent immunoassays. However, these assays are less accurate when testosterone concentrations are too low. Liquid chromatography-tandem MS (mass spectrometry) and gas chromatography-MS are also used for more accurate results, mainly when testosterone levels are at the low and high extremes. Measuring free testosterone is done after it has been separated from the protein-bound forms. This can be done using equilibrium dialysis or ultracentrifugation. Equilibrium dialysis is the most common method, and it involves introducing testosterone isotopes into a patient sample. The free testosterone concentration is estimated based on the distribution of isotopes in the dialysis membrane. The bioavailable testosterone can be measured using ammonium sulfate, which influences the testosterone bound to SHBG. Assessing testosterone levels began approximately 30 years ago. Tests were done on small blood samples, but their accuracy could have improved. Current testosterone assays are more sensitive, require a smaller serum sample, and are more affordable. They can be done using nonradioactive methods in reference labs.   How is testosterone level measured? Up to 98% of the testosterone found in the bloodstream is bound to proteins such as albumin and SHBG. Just about 2% is free. Albumin-bound testosterone and free testosterone are known as bioavailable, and tissues can easily use them for androgen action. On the other hand, total testosterone can be measured using nonradioactive immunoassay and chemiluminescent detection. These methods offer accurate results if the male patient has testosterone levels in the normal range, such as 300-1000 ng/dL. However, these assays recorded low testosterone limits of approximately 132 ng/dL, which is not customary in healthy men. Clinicians have wondered why this happens and how they can improve the accuracy of testosterone assays when T concentrations are deficient. Regarding total testosterone assays, the gold standard is a steroid-free serum interacting with gravimetrically-determined amounts of testosterone. Independent measuring methods, such as liquid or gas chromatography with mass spectrometry, are also used. Susceptible tests are necessary for women to determine total and free testosterone levels because women have much lower amounts of testosterone in the bloodstream.   Dr. Wang's analysis of testosterone assays In a paper published in 2004, Dr. Wang and her colleagues compared multiple testosterone immunoassays (both manual and automated ones) with chromatography-tandem mass spectrometry. The results were very accurate for the latter option, and the test was performed on serum samples from patients with different testosterone levels (ranging from under 150 ng/dL to 1,500 ng/dL). This means that most of the automated and manual assays were accurate compared to LC-MSMS, but some tests provided inaccurate results. The authors concluded that most manual and automatic testosterone immunoassays are ideal for differentiating eugonadal men from hypogonadal men. Still, they weren't accurate for women or children who haven't reached puberty yet. It’s essential to notice that these automated and manual testosterone immunoassays are compared with gold standards of adult male reference ranges. These ranges are set by individual laboratories and are usually monitored by the College of American Pathologists. That’s why you’ll find several testosterone tests on the market. Getting the right one is essential to obtain the most accurate results.   4 Types Of Testosterone Tests You Can Buy Today There are four different testosterone assays you can choose from to determine the amount of testosterone in your bloodstream accurately.   #1 - TESTOSTERONE Total and Free (Regular) This test is ideal for people with testosterone levels in the normal range. It measures total and free testosterone using direct analog/radioimmunoassay (for free T) and electrochemiluminescence immunoassay (for real T). On the other hand, if you know you have deficient testosterone levels (hypogonadism and testosterone levels below 150 ng/dL) or very high testosterone levels (you are a bodybuilder with T levels over 1500 ng/dL). You might want to use the LC/MS test because it’s more accurate. If your testosterone levels are very high, the test will show above 1500 ng/dL, not the exact number (such as 1,700 or 1,800).   #2 - Testosterone Free and Weakly Bound (Bioavailable Testosterone) Bioavailable testosterone can be used for steroid-receptor interaction. This test measures the amount of free and weakly bound testosterone in the bloodstream. The test doesn’t look at the testosterone bound to SHBG because this type is biologically inactive as it has a high binding affinity. On the other hand, weakly bound testosterone is usually derived from albumin and has a low affinity, which means that it can quickly dissociate and become available for interaction.   #3 - Testosterone, Free, Bioavailable, and Total, LC/MS (No Upper Limit) This test has no upper limit for either type of testosterone, such as free, total, or bioavailable. It uses more complex measuring assays such as liquid chromatography-tandem mass spectrometry to determine testosterone levels accurately. However, this test is more suitable for bodybuilders, who are known to have very high testosterone levels. If you are not into bodybuilding or think you have below-normal testosterone levels, this test is not ideal for you. Other tests are more economical and can be used to determine your testosterone levels more accurately. If you are on testosterone replacement therapy, you might want to choose a test that has no upper limit on total testosterone and up to 50 ng/dL limit on free testosterone. An even more affordable test for people on testosterone replacement therapy has an upper limit of 1,500 ng/dL on total testosterone and a 50 ng/dL limit on free testosterone.   #4 - Testosterone, Total, LC/MS (No Upper Limit) This test measures only total testosterone by liquid chromatography or mass spectrometry. This test is ideal if your testosterone levels are deficient (both men and women). It is also suitable for high testosterone levels due to TRT or bodybuilding.  The test is the most accurate for testosterone concentrations under 150 ng/dL or above 1500 ng/dL for total testosterone.     Why should you test your testosterone levels? Measuring testosterone levels has become increasingly popular nowadays, thanks to direct-to-consumer labs that are affordable and easy to use. Males and females can buy one of the tests described above and determine the actual amounts of testosterone in their bloodstream. But why is this a good idea? First, if you have common testosterone deficiency symptoms such as fatigue or low sex drive, then measuring your testosterone levels is highly recommended. This will help you decide whether a lack of testosterone is the problem and whether you should try testosterone replacement therapy. Testosterone tests give you a broader insight into your hormonal health. Secondly, if you’re on testosterone replacement therapy already, the test results might provide good feedback on your progress. The clinicians who conduct these tests can give you valuable adviceLong-Term, such as how often to take testosterone gels or injections, whether you should reduce or increase the dosage, etc. If you’re a bodybuilder, keeping your testosterone levels in check also helps you monitor your progress. After all, testosterone is vital for muscle development, and if you have sufficient amounts of it, you’ll ensure muscle growth in the long run. Testosterone is essential for women too. This hormone is linked to mental alertness, good mood, and increased sex drive. Testosterone deficiency in women can also lead to low productivity at work and poor physical performance in the gym. Numerous advancements in the medical field coupled with improved testing devices make measuring testosterone levels a more affordable and accurate process.   How to get a testosterone test? Visit Discounted Labs, pick your favorite testosterone blood tests, and you’ll be able to get your results in a few business days. You can also order other blood tests to check your glucose levels, cholesterol, triglycerides, blood count, and more!  

Table of Contents 1. Biotin Biotin Uses and Supplementation How Biotin Affects Test Results What Are the Lab Tests Which Might Be Affected by Biotin Supplementation? What Supplements Have Biotin? 2. Age 3. Urinary Tract Infection 4. Prostate Procedures 5. Bicycle Riding 6. Obesity or High Body Weight 7. Medications 8. Biological Rhythms 9. Pregnancy 10. Food and Water 11. Caffeine, Alcohol, and Tobacco 12. Exercise Get Your Health Checked Up Today!   According to the World Health Organization, chronic diseases kill millions of people each year. Diabetes alone accounted for nearly 1.6 million deaths in 2015. Deaths caused by neurodegenerative diseases such as dementia doubled since 2000, and this number is expected to grow in the upcoming years. Although these are alarming facts, you might be happy to find out that numerous diseases and injuries, particularly chronic illnesses, can be prevented. To prevent a disease, you first need to be aware of it. To be aware of it, you need to do the right thing and get your health checked periodically. Discovering a predisposition to the disease earlier on gives you a massive advantage. You’ll be able to follow special treatments and minimize its risks or eliminate them. But how to get tested for various diseases which might affect you? Well, one of the simplest and most efficient ways is by using direct-to-consumer labs. These are usually discount labs you can purchase online at affordable prices and have your general health checked in a matter of days. No doctor visit is required so that you can quickly check your blood tests and monitor your health if you are an educated patient. However, you need to keep in mind that there are many factors which can influence the results of your lab tests. In other words, these factors can reduce the accuracy of your results, and that’s why you need to follow up the doctor’s advice before drawing blood for testing. This article is going to offer you a broader understanding when it comes to factors which influence lab tests. Keep reading to learn more about your health and how you can optimize the results of your lab work investigations. 1. Biotin Biotin is also known as vitamin B7 or vitamin H. This is a coenzyme the body needs for different metabolic processes. For example, the body needs biotin to optimize the metabolism of fat, carbohydrates, and protein. At the same time, biotin is also needed for the production of certain hormones. You can find biotin in fish, eggs, meat and certain vegetables such as spinach and broccoli. However, you can also take biotin supplements if needed. Adults need about 30 micrograms of biotin per day. Having more biotin in your system is not a problem, but it might affect some lab tests you make. For example, it can interfere with the results in certain blood tests, which might lead to an incorrect diagnosis of various health ailments. Biotin Uses and Supplementation As mentioned earlier, biotin is present in various pills and supplements you can buy online. For example, biotin can be used for treating alopecia, which is a health condition that makes people lose their hair. Doctors prescribe a dose of 5,000 to 10,000 micrograms of biotin per day to treat such health problems. At the same time, biotin can also be prescribed to pregnant women to support the healthy development of the baby. There are studies performed by researchers at various universities which prescribe large biotin doses to treat various problems with the nervous system. For example, multiple sclerosis might be treated with around 300,000 micrograms of biotin per day. Some people also use biotin to treat nail and skin problems since no studies are suggesting that a high amount of biotin can lead to health complications or injuries. How Biotin Affects Test Results Although supplementing with biotin can be beneficial for the body, this substance can greatly interfere with test results. The FDA (Food and Drug Administration) mentioned that biotin could alter blood test results and cause incorrect diagnosis for certain health conditions. It is recommended that you stop biotin supplementation at least 72 hours before offering a blood or saliva sample. What Are the Lab Tests Which Might Be Affected by Biotin Supplementation? There are many blood tests which can be affected by excessive biotin levels in your bloodstream. Some of these tests include vitamin D tests, any tests which measure the thyroid hormones in your body as well as tests which look at the FSH and LH hormones. Troponin is another type of test commonly used to diagnose heart attacks and other problems related to the cardiovascular system. If you’re planning to do such blood tests in the future, make sure you put your biotin supplementation on hold to ensure you get accurate results. What Supplements Have Biotin? On top of getting biotin from your foods, this substance can also be taken from various vitamins or supplements available in drug stores. For example, most multivitamin pills, B-complex vitamins, and coenzyme R have high amounts of biotin in them. Similarly, supplements with vitamin H and prenatal vitamins might also contain biotin. If you’re taking some supplements for hair growth and skin improvement, chances are that you’re also getting some biotin from those. Look on the labels of the supplements you take and look for “biotin,” “vitamin B7”, “vitamin H,” or “coenzyme R” to see if your pills contain biotin. If you have been instructed to stop biotin supplementation a few days before your blood test but forgot to do so, make sure that you inform your doctor about it. Your health practitioner needs to know this is the case your results show inaccurate or confusing results. 2. Age The advancing age of a patient also significantly influences the results of a particular blood test. In most cases, people of an elderly age tend to receive a higher percentage of incorrect/inaccurate results in comparison with younger adults. That’s because certain hormones and substances in the body are interpreted differently by lab tests as their levels increase or decrease with age. To give you an accurate example, a lipid panel of an older adult is much different than the one of a young person. The levels of triglycerides, good cholesterol, and bad cholesterol tend to increase with age up to about 55-60 years in males and around 65 years in females. Some studies show that triglyceride levels continue to increase in senior females. When this happens, doctors don't use reference values based on age anymore because they are inefficient in people of elderly age. Instead, they test the risk of cardiovascular disease and formulate treatment options based on that because this method is much more efficient. At the same time, there are blood tests which measure the prostate-specific antigen (PSA) levels in men. PSA can increase in people of an elderly age as more PSA gets into the bloodstream and interferes with the test results. 3. Urinary Tract Infection Another factor that can influence the results of a PSA test consists of urinary tract infections. Various urinary tract bacteria can drastically alter the test results and lead to inaccurate diagnosis. That’s why it’s a good idea to tell your doctor if you ever had urinary tract infections so he can make a more accurate diagnosis when testing your PSA levels. 4. Prostate Procedures People who have had prostate procedures done are more likely to receive an incorrect diagnosis when doing prostate tests. For example, prostate surgery or biopsy, as well as prostatitis, can cause abnormal levels of PSA in the body. These factors can interfere with test results and cause false diagnosis. The doctor will eventually inform you when it's a good time to have a prostate test after you have had done a prostate surgery or biopsy. 5. Bicycle Riding Some studies have found that riding a bicycle can put a lot of pressure on the prostate, which can increase PSA levels. Therefore, prostate test results can come back with incorrect information, which leads to a false diagnosis. Another thing that can increase PSA levels is ejaculation since it makes more PSA leak into the bloodstream and affects the test results. 6. Obesity or High Body Weight Obesity is another health issue that affects the results of various blood tests. For example, obese men have greater BMI, and they usually have lower PSA concentrations. That's because obese men usually have a larger blood volume where PSA can get diluted. As a result, a prostate test can return false PSA results which affect the diagnosis set by the doctor. Similarly, obesity can also affect the results of rheumatoid arthritis tests. During those tests, various inflammatory markers such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are checked to detect the level of inflammation in the body. Some studies show that obese people tend to have higher levels of ESR and CRP in their bodies, and this can interfere with the results, leading to false diagnosis. Buy a CRP Test Here Another blood test that can be affected by body weight is creatinine (used to assess kidney function). This test result may be artificially elevated in people with higher body weight or lean mass.  Cystatin C may be a better indicator of kidney function in those patients. 7. Medications Any medication that you might take before doing a blood test can significantly influence the results. Make sure that you inform your doctor about the pills you take, so he can take that into account when interpreting the results. If it is possible, you can discontinue certain medication (after you have received doctor’s approval) to make sure that your blood tests are more accurate. There are many types of medications which can influence the results of blood tests, including prostate test, inflammation tests, etc. For example, nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, ibuprofen, and naproxen can alter the results of a blood test. Other important ones include blood pressure medication, which is known as thiazide diuretics. Some of the most common medication in this category include hydrochlorothiazide, chlorothiazide, and others. These medications tend to lower PSA levels and lead to a false diagnosis in prostate blood tests. 5-alpha reductase inhibitors also affect PSA levels. These inhibitors are represented by dutasteride and finasteride, which also decrease the PSA levels by almost 50 %. Metformin, a popular diabetes drug that is gaining anti-aging interest, can reduce B vitamin blood levels. This fact needs to be considered when testing for B-12 or other vitamins. 8. Biological Rhythms Various hormones and other substances in the body have significantly different levels at certain moments of the day. For example, you have different cortisol or testosterone levels in the morning compared with those in the evening. That’s why it’s important to do certain tests at specific moments of the day to ensure the accuracy of the test. Your doctor will usually inform you about that and tell you when it’s the best time for a blood test. Testosterone blood levels peak early in the morning, usually between 7 am, and 9 am. This time of the day is when a testosterone blood test should be done. Throughout the day, testosterone levels slowly decrease, and by evening, they are about two times lower than in the morning. The same story goes for cortisol levels as well. The levels of cortisol in your body peak early in the morning, and they gradually decline by 50%-100% until the end of the day. The time of the month or year is also very important when doing health checkups. For example, getting more vitamin D into your body relies on how much you are exposed to the sun. You can also get supplements with vitamin D if necessary, but sun exposure is one of the best and most efficient ways to get vitamin D. The levels of this vitamin in your bloodstream need to be interpreted based on the time of the year. For example, it’s normal to have the lowest levels of vitamin D during winter times since that’s when sun exposure is limited. 9. Pregnancy A pregnant woman can also have different test results in comparison with one who isn't pregnant. Pregnancy can change the amount of blood in the body, influence liver hormones, renal function, and other metabolic processes. Changes in hormone levels depend on the pregnancy stage, and they are usually compared against reference values. Physicians can give a pregnant woman more information on how to interpret these results and what they should do about them. 10. Food and Water The foods you eat and beverages you drink can influence the results of blood tests. For example, fasting, restricting calories, or being dehydrated can lead to incorrect test results and false diagnosis. To give you an example, a diet rich in protein can lead to increased uric acid levels, and this will be shown in various blood and urine tests. Similarly, a diet which is low in carbohydrates can increase the levels of ketones (ketogenic diet). If a person is a vegan or vegetarian, the levels of vitamin B12 in his/her bloodstream will be low. Some studies have shown that carbohydrates can temporarily decrease testosterone blood levels, so it is important to measure testosterone before breakfast. Fasting is needed before drawing blood for most blood testing. Patients are usually asked to fast for about 8-12 hours before doing a blood test. Fasting is important when checking lipid levels, blood sugar levels, some hormones, and substances in the body. Not fasting before a CMP test, for example, can lead to an incorrect diagnosis of diabetes type 2 since glucose can be elevated, which is a life-threatening condition if not treated properly. The Lipid Panel test (Triglycerides, LDL and HDL cholesterol) also requires fasting.  Failure to do so may cause the triglycerides value to be higher than normal. For more information about which tests require fasting, read: Fasting Blood Tests - Everything You Need to Know Dehydration also plays a vital role when it comes to blood testing. It can increase blood test values by decreasing the water content of the blood. It can be seen as an imbalance in sodium and potassium levels and lead to false diagnosis. For example, dehydration can affect albumin levels, blood lipids, creatinine (kidney), hematocrit, and some hormones in the body. 11. Caffeine, Alcohol, and Tobacco Drinking a lot of caffeine from coffee or green tea can also affect some blood test results. Although more studies are necessary when it comes to caffeine, there is a chance that this substance can alter blood glucose levels and temporarily increase them. Caffeine usually passes through the body in around 5 hours, so its effects are less significant in comparison with other substances. Caffeine can also affect hydration, a factor mentioned above. Last but not least, caffeine can increase blood pressure in some people. The lab technician may be alarmed about your blood pressure before drawing your blood. Alcohol, on the other hand, has a more significant effect on blood tests, depending on how much is consumed and when. For example, this substance might lower serum glucose levels in people of all ages and increase plasma lactate. These changes can happen, especially if alcohol is consumed 2 or 4 hours before drawing blood for testing. At the same time, chronic alcohol consumption can lead to other problems such as elevated triglyceride levels, elevated creatine kinase levels, elevated liver enzymes, and increased uric acid. As a result, blood tests can be affected, and the doctor could subsequently give a false diagnosis. Frequent alcohol consumption can also lead to mineral and vitamin deficiencies, particularly decreasing the B-complex vitamins. This potential B vitamin deficiency is a concerning problem in chronic alcohol abusers since the vitamins in the B complex are responsible for the proper functioning of the brain and nervous system. Patients are asked to cease alcohol consumption at least 24-48 hours before drawing blood for testing. This period should give the body enough time to process the alcohol consumed and prevent blood test levels from being affected. However, liver enzymes and triglycerides may not return to baseline in that short period. Another substance of concern is tobacco, which can also have a profound influence on blood test results. Those who smoke cigarettes have higher levels of nicotine in their bodies. As you probably know, nicotine is a drug which can increase cortisol levels and elevate concentrations of fatty acids in the blood. It may also increase hematocrit (red blood cell proportion, part of the CBC panel) since the body tries to produce more red blood cells to compensate for the lower oxygen level it is getting due to smoke in your lungs. As a result, blood tests can come up with confusing results. Whether cigarette smoking is acute or chronic, it’s detrimental for one’s health, and it can mess up with lab investigations. Cigarettes also contain thousands of toxins and chemicals which are harmful to the body, including arsenic and cadmium. These can increase the biomarkers of inflammation in the blood and show up in blood tests. 12. Exercise Physical exercise is one of the most important factors that influence blood test results. Whether you do resistance training, HIIT, yoga, or go for a bicycle ride, this activity could influence some of your blood tests. For example, after an intense session of exercise, the levels of creatine kinase (CK) in the body are increased. CK can remain elevated for up to a week, and this will be picked up on blood tests. Different types of exercises can also increase or decrease thyroid hormone blood tests. For example, doing anaerobic exercises can elevate the levels of thyroid stimulating hormone (TSH) in the body. At the same time, anaerobic exercises can also decrease FT3 levels. It is estimated that thyroid hormone levels can be altered for several hours or even several days, depending on the individual and his fitness level. Marathoners are also highly exposed to have altered hormonal levels before and after completing a run. For example, the levels of glucose, albumin, protein, and bilirubin were measured in professional marathoners 4 hours after a run. All these hormones were increased. Studies performed on professional football players who train regularly also reveal that frequent exercise can boost immune function. One study looked at the white blood cell count in 31 males who didn’t do any exercise as well as 32 males who were playing football for a year. The white blood cell count was significantly higher in football players, and this leads to the conclusion that regular exercise can improve the immune response of a person. In another study performed on marathoners, it has been discovered that regular jogging for long periods can reduce the levels of C-reactive protein (CRP), which is a known marker of inflammation. However, excessive running can increase CRP and other inflammatory markers. When doctors perform an inflammation panel, they test the CRP levels primarily. They want to determine if the inflammation in the body is chronic or acute. Having lower CRP levels as marathoners do helps them avoid chronic inflammatory diseases. On the other hand, some marathoners also had high PSA levels after completing a marathon. PSA stands for prostate-specific antigen, and it’s a marker of prostate disease. 2 out of 21 marathoners had increased PSA levels after running a marathon, which might state a problem with the prostate tissue. However, this can be a false diagnosis since vigorous exercise tends to increase PSA levels in certain people. That’s why doctors recommend performing prostate tests twice if PSA levels are increased as a result of exercise. At the same time, one should wait at least 24 hours after exercise to do a prostate exam to get a more accurate diagnosis. Last but not least, weightlifting has been shown to result in profound increases in liver function tests in healthy men used to moderate physical activity, not including weightlifting. Liver function tests are significantly increased for at least 7 days after weightlifting. It is important to impose relevant restrictions on heavy muscular exercise prior to and during clinical studies.   Get Your Health Checked Up Today! It’s amazing that we live in an era when we can order a blood test online and get the results back in a few days. The whole process is also confidential and super-affordable! You should take advantage of that and order your first blood test today. If you don’t know what to start with, check out the popular tests on DiscountedLabs, and explore the multitude of blood panels available. These tests are inexpensive, and they’ll help you get your health under control!

What is Biotin? Biotin, also known as vitamin B or vitamin H, is a dietary supplement that is often taken for hair, skin, and nail health. It is marketed under various names, including vitamin B7, vitamin H, and coenzyme R. Recent studies have shown the benefit of biotin for medical conditions such as hair and nail problems, diabetes mellitus, peripheral neuropathy, and multiple sclerosis. Biotin supplements taken at common over-the-counter doses can interfere with the results of certain hormone assays, giving falsely high or low results that could lead to a misdiagnosis, researchers reported. Biotin deficiency, while unusual in modern times, can still occur and may lead to various health issues. Biotin supplements in very large amounts (10–15 mg) (333 times the daily recommended amount) have become popular because they are thought to help with hair growth, diabetes, lipid disorders, and diabetic peripheral neuropathy. They are also thought to help with treatment of mitochondrial energy metabolism disorders, lipid disorders, and diabetic peripheral neuropathy. The Mayo Clinic has also reported on the potential interference of biotin with hormone tests. Biotin At A Glance Many patients are taking megadoses of biotin that can cause falsely high and falsely low results in a variety of laboratory tests, including thyroid tests. Biotin has no impact on hormone tests used with liquid chromatography or mass spectrometry. Patients are taking these supplements mainly to improve their hair, skin, and nails and might not consider them medications to report on their list. Most multivitamins do not have enough biotin for concern, however. Biotin interference with lab tests could be causing misdiagnoses — and even mistreatment — in an unknown number of patients. Biotin Affects Blood Tests Performed with Immunoassays High doses of biotin may interfere with lab tests because biotin is a common component of many immunoassays in the form of biotinylated antibodies or analogs. If you are taking a biotin supplement, please stop it at least 4 days before getting your blood drawn. Biotin supplements taken at common over-the-counter doses can interfere with the results of certain hormone assays, giving falsely high or low results that could lead to a misdiagnosis and mimic the typical biochemical picture of Grave's disease. Biotin supplements, at very large doses of 10–15 mg (333-fold greater than the dietary recommendation), have become popular for the presumptive benefits of stimulating hair growth, diabetes, lipid disorders, and diabetic peripheral neuropathy. Biotin interference is particularly prominent in competitive immunoassays, which are commonly used for low-molecular-weight targets such as T4, T3, and cortisol. Therefore, it is important to stop taking biotin supplements before undergoing any blood tests performed with competitive immunoassays to avoid misleading results. Biotin interference causes inaccurate results, highlighting the importance of avoiding biotin supplements before blood tests, particularly those involving parathyroid hormone levels. What Are the Typical Tests That Higher-Dose Biotin May Affect? Biotin can affect a wide variety of laboratory tests. Examples include tests for: Troponin—a test used to help diagnose heart attacks Thyroid hormone tests, such as thyroid stimulating hormone (TSH), thyroxine (T4), and triiodothyronine (T3) tests Other hormones, such as parathyroid hormone (PTH), cortfollicle-stimulating hormone (FSH) and luteinizing hormone (LH), Vitamin D levels How Much Does Taking Biotin Actually Affect TSH Results? Based on the search results, taking high doses of biotin (vitamin B7) can significantly interfere with thyroid function tests, including TSH (thyroid stimulating hormone), and lead to inaccurate results. The key points regarding biotin's effect on TSH are:When using immunoassays that use the biotin-streptavidin binding mechanism [1, 3, 6, 7, 9], biotin interference often leads to TSH levels that are too low. This is because too much biotin makes it harder for the TSH-antibody complex to bind to the streptavidin-coated solid phase in these "sandwich" immunoassays. The degree of TSH suppression depends on the dose of biotin and the specific assay method used by the laboratory [1, 3, 6, 7]. Higher biotin doses generally cause more suppression of the measured TSH level. One study found that taking 10 mg of biotin daily for 7 days caused TSH levels to be falsely low for up to 8 hours after the last biotin dose when measured on certain assay platforms like Roche Cobas and Beckman UniCel. With a 10 mg biotin dose, TSH remained falsely low for 1-2 days. Another study showed that taking 10,000 mcg (10 mg) of biotin daily caused TSH levels to be falsely low, mimicking hyperthyroidism, even though the patient was clinically euthyroid. Biotin interference can lead to misdiagnosis of hyperthyroidism or mismanagement of thyroid disorders like thyroid cancer if TSH is being used to monitor suppressive levothyroxine therapy [4, 7]. To sum up, high-dose biotin supplements, which are often used to treat hair, skin, and nails, can significantly lower measured TSH levels through assay interference. This could lead to a wrong diagnosis and bad treatment changes if biotin intake is not taken into account. The effect is dose-dependent and can last for 1-2 days after stopping high biotin doses. [1,3,6,7,9,12] Discussion - Our patient, who was taking 10000 mg/day of biotin for multiple sclerosis, showed lab results of falsely elevated free T3 and T4 and falsely low TSH, mimicking symptoms of hyperthyroidism. His thyroid function report returned to normal when he stopped taking biotin for five days, showing no signs of hyperthyroidism. When to Stop Biotin Before Thyroid or OTher Hormone Tests High doses of biotin can interfere with certain thyroid tests and other hormone tests, leading to inaccurate results. It is recommended to stop taking biotin at least 2 days before undergoing any thyroid function tests to ensure the most accurate readings. This precaution is essential as biotin ingestion can skew thyroid hormone levels in blood tests, potentially causing misdiagnosis or inappropriate treatment. The American Thyroid Association (ATA) has recommended stopping biotin at least 2 days prior to lab testing, specifically thyroid labs, to avoid spurious results, especially for free thyroxine (FT4) and thyroid stimulating hormone (TSH) levels. Always consult with your healthcare provider for specific guidance on when to discontinue biotin before thyroid testing. The FDA Stance on Biotin The FDA has said these about biotin's potential interference with lab tests: Know that biotin is found in multivitamins, including prenatal multivitamins, biotin supplements, and supplements for hair, skin, and nail growth in levels that may interfere with laboratory tests. However, the amount of biotin can vary significantly among different products. Consider that the daily recommended allowance for biotin is 0.03 mg (300 mcg) and that amount does not typically cause interference in lab tests Biotin Can Interfere with Certain Blood Tests: Physicians Should Warn Patients Clinicians are cautioned to act decisively given the risk of inaccurate or missed diagnosis and in light of the urgency that prompted a Food and Drug Administration (FDA) Safety Communication on this very topic. The FDA recommends that clinicians take the following precautions: Talk to your patients about any biotin supplements they may be taking, including supplements marketed for hair, skin, and nail growth Be aware that many lab tests, including but not limited to cardiovascular diagnostic tests and hormone tests, that use biotin technology are potentially affected, and incorrect test results may be generated if there is biotin in the patient’s specimen Communicate to the lab conducting the testing if your patient is taking biotin If a lab test result doesn’t match the clinical presentation of your patient, consider biotin interference as a possible source of error Know that biotin is found in multivitamins, including prenatal multivitamins, biotin supplements, and dietary supplements for hair, skin, and nail growth in levels that may interfere with lab tests Report to the lab test manufacturer and the FDA if you become aware of a patient experiencing an adverse event following potentially incorrect laboratory test results due to biotin interference. Common Questions and Answers: Does biotin interfere with TPO antibodies on a thyroid test? Biotin can interfere with TPO (Thyroid Peroxidase) antibody test results, leading to falsely elevated or decreased levels. If you are taking biotin supplements and are scheduled for a thyroid test, it is recommended to inform your healthcare provider about your biotin use. This will allow them to provide guidance on whether you need to stop taking biotin before the test to ensure accurate results. It's important for healthcare professionals to have all the necessary information to interpret your test results correctly and make appropriate recommendations based on accurate data. How does biotin interact with thyroid medication? Biotin, also known as vitamin B7, is a water-soluble vitamin that is often included in multivitamin supplements and promoted for its potential benefits for hair, skin, and nails. However, recent literature suggests that high doses of biotin can interfere with certain thyroid function tests, leading to inaccurate results. The American Association of Clinical Endocrinology advises discussing biotin therapy with your healthcare provider, especially if you are taking thyroid medication, because this interference is more common in people who take biotin supplements at levels much higher than the recommended daily intake. If you are taking thyroid medication and considering adding a biotin supplement to your routine, it is important to discuss this with your healthcare provider. They can provide guidance on the appropriate dosage of biotin and how it may interact with your thyroid medication. In some cases, they may recommend temporarily stopping the biotin supplement before thyroid function tests to ensure accurate results. It is always best to consult with a healthcare professional when making changes to your medication or supplement regimen to avoid any potential interactions or adverse effects. Can biotin affect thyroid function? Biotin can interfere with some thyroid function tests, leading to inaccurate results. If you are undergoing thyroid function testing, it is recommended to inform your healthcare provider if you are taking biotin supplements, as they may advise you to discontinue them temporarily before the test. It's important to follow your healthcare provider's guidance to ensure accurate test results and proper interpretation. Click here for other FACTORS THAT CAN AFFECT THE ACCURACY OF YOUR BLOOD TEST RESULTS  References "Thyroid hormone interference caused by biotin: review and case illustration" - PMC "Assessment of Biotin Interference in Thyroid Function Tests" (MD Journal) "The effect of biotin on thyroid function tests: A synthetic overview" (PMC) "Case of a misdiagnosed thyroid disorder due to biotin interference" - Journal of Medical Case Reports "Biotin Interference with Thyroid Function Tests - Safety Alert" (Health Sciences Authority) "Biotin supplementation and its impact on thyroid function testing: Analysis of a community population" (PMC) "Review on the interference of dietary supplements on clinical laboratory tests: Biotin and its effect on thyroid function testing" (International Journal of Thyroidology) "Biotin Supplementation: Implications for Thyroid Testing" - Thyroid.org "January 2016 - Thyroid Month: Beware of Biotin" (Endocrine News) "Understanding Biotin Interference in Thyroid Tests" (Medscape) "Biotin and Thyroid Testing: A Quantitative Review" (Journal of Endocrine Society) "New Insights into Biotin Interference with Thyroid Tests" (Thyroid.org) FDA In Brief: FDA provides draft recommendations to diagnostic manufacturers to help reduce risks of biotin interference with certain lab tests The FDA Warns that Biotin May Interfere with Lab Tests: FDA Safety Communication  

Testosterone is routinely associated with "manliness," strength, muscles, aggressiveness, and even roaring V8 engines sometimes. This is the main male sex hormone and women have a little bit of it too. However, the story behind testosterone is a little bit more complex and worth discovering. Free testosterone is usually the one that provides all the benefits when it comes to sex drive, muscle gains, and better cognition. Dive into this article to learn more about testosterone fractions, how to test your testosterone levels, and how to increase free testosterone. What is free testosterone? If you do a testosterone blood test, you're usually getting the total testosterone levels circulating through your bloodstream. Total testosterone is the sum of protein-bound testosterone and free testosterone. Believe it or not, free testosterone only makes up about 1-2% of your total testosterone levels. This substance is freely moving throughout your body, and tissues can easily absorb it to cause chemical reactions. Protein-bound testosterone makes up about 98% of your total testosterone. It splits into two categories: albumin-bound testosterone and SHBG-testosterone. SHBG stands for sex hormone-binding globulin. It's a substance that attaches to testosterone, making it unavailable for organs and tissues to absorb. Albumin is one of the most prevalent protein types in the human body. Approximately 38% of your total testosterone is bound to albumin. This binding is weak, meaning that some organs and tissues can still absorb the albumin-bound testosterone and use it for various purposes. Since 1-2% of your testosterone is free, the remaining 60% of your total testosterone is SHBG-bound. The sum of free and albumin-bound testosterone is also known as bioavailable testosterone. How to Increase Free Testosterone Remember that free testosterone is the one readily available for grabbing by tissues and organs. This is the one usually associated with muscle gains, male attraction, and libido. If you want to increase it, check out these science-based methods. Get More Sleep Believe it or not, sleep is closely related to the production of testosterone in your body. If you don't get enough sleep, your body doesn't produce as much testosterone as it should. This refers to the total level of T and consequently, your free T is also affected. Maintain a Healthy Weight Being overweight or obese can dramatically reduce your total testosterone levels and, implicitly, your free testosterone levels. This is true for both young males and seniors. Therefore, make sure that you lose the extra weight if necessary and this will naturally boost your free testosterone levels. Eat a Balanced Diet This is probably one of the most common pieces of advice you hear daily, but it's worth repeating. A diet filled with junk and processed foods, sodas, too much caffeine, and alcohol will ruin your testosterone levels over time. On the other hand, if you eat more vegetables and fruit, whole grains, and light meat such as fish and chicken, and incorporate regular physical activity, you'll be on the safe side. Normal and high levels of testosterone are commonly associated with a healthier diet that includes enough calories and healthy fats, as well as regular physical activity and training intensity. If you want to increase your free testosterone, you might need to make sensible diet adjustments such as incorporating a balanced mix of protein, fat, and carbs from whole foods into your meals to support optimal hormone levels and weight loss. A 2021 systematic review and meta-analysis suggests that a low-fat diet and regular physical activity may decrease testosterone levels, highlighting the importance of a balanced diet and physical activity for hormonal health. Get Rid of Stress Just like lack of sleep, too much stress is also bad for your testosterone levels. It will basically slow down the production of testosterone and make you feel tired, lethargic, and confused. Stress is inevitable, so you cannot eliminate it. But you can do something to reduce it. Learn what works for you. For example, you can go to a yoga class. You can practice breathing exercises. You might want to give meditation a shot. You could just watch your favorite series online and relax in bed for an entire afternoon. All these activities will reduce your stress hormones and let your body naturally increase testosterone levels. Do Resistance Exercises Lifting weights has a lot of benefits. You don't need to become a professional bodybuilder and sweat for hours in the gym every week. A few resistance exercises several times per week is usually enough to reap the benefits of this activity. Compounded exercises such as bench-press, deadlifts, and weighted squats are difficult, but they engage most of the muscle groups in your body. This will force your body to produce more testosterone to repair and rebuild stronger muscle fibers. You are not alone in your fitness journey, either. Hire a fitness instructor and follow his/her advice. This will keep you motivated and safe while performing weighted exercises. Get More Vitamin D and Zinc Your body metabolizes vitamin D as a result of direct sun exposure. However, most people around the world are deficient in vitamin D. You need to take it as a supplement to achieve normal vitamin D levels and correct deficiencies. Some studies show that vitamin D is commonly associated with normal and high levels of testosterone. If you take enough vitamin D, you're helping your normal production of testosterone and even increasing it slightly. Zinc is another mineral essential for testosterone production, particularly in postmenopausal women and older men. A zinc deficiency is correlated with a drop in testosterone levels, making it important for women and older men to consider taking supplements for men’s health. In fact, in one study, zinc supplementation increased testosterone levels and improved sexual function in postmenopausal women with low blood levels of zinc. Men usually need about 11 mg of zinc per day and you can easily get that from a supplement. Zinc also boosts muscle gain and libido, so you get additional benefits too. Additionally, optimizing vitamin D levels through lifestyle changes and testosterone therapy can also help improve daytime testosterone levels and increase hours of sleep. A year-long trial showed that daily supplementation of just over 3,000 IU significantly increased total and free testosterone in both men and women, correcting vitamin D deficiency and promoting optimal testosterone levels for men’s health. Before beginning high-dose vitamin D supplementation, it is best to know where both values stand. Increase Your Testosterone Dose if on TRT If you are on TRT, increasing the dose can decrease SHBG and increase free testosterone. However, be aware that increasing T dose may also increase hematocrit (blood viscosity) and decrease good HDL cholesterol, so talk to your doctor first. Check Out These Affordable and Accurate Testosterone Tests! Today you can test your testosterone levels and other hormones associated with them with a simple blood test. The liquid chromatography/mass spectrometry (LC/MS) testing technology has become very advanced and the results are increasingly accurate, so why not try it for yourself? For example, you can order this highly sensitive LC/MS total and free testosterone test plus bioavailable T and SHBG. This group of tests checks your total, free, bioavailable, albumin-bound, and SHBG-bound testosterone levels, providing important information about your overall health and potential health conditions, including testosterone deficiency or hypogonadism. There are no limits applied to this test panel, so you get a realistic result using the latest medical technology available. Additionally, you can also check your testosterone levels, physical performance, muscle mass, and potential for erectile dysfunction through affordable and accurate tests that require only small amounts of blood. These tests can also help identify symptoms of low testosterone, such as low libido, and provide insights into how to boost testosterone levels for improved physical performance and quality of life. If you're on TRT, you can also order the Basic TRT Monitoring Panel. This comprehensive test helps people who are on testosterone replacement therapy monitor their hormones. It includes a metabolic panel, blood count panel, sensitive estradiol, testosterone tests, and more. For more testosterone tests, check these testosterone test panels from DiscountedLabs.com Here, you will find the most affordable testosterone blood tests in the United States! Citations Grip Strength and Muscle Mass in Healthy Older Adults The Role of Testosterone in Male Reproductive Function Testosterone, Aging, and Male Osteoporosis The Effects of Testosterone on Cognitive Function Testosterone and Aging: Clinical Research Directions Free Testosterone: Understanding Its Role in Erectile Dysfunction Testosterone Therapy and Cardiovascular Risk The Benefits of Testosterone: Healthline Guide What’s the Difference Between Total and Free Testosterone? Testosterone and Male Behaviours: The British Psychological Society Testosterone and Mortality: JAMA Study University of Florida PathLabs: Free Testosterone Test How Much Testosterone Affects Muscle Growth: VICE Testosterone and Health Outcomes in Men Testosterone Total and Free: Rochester Encyclopedia Testosterone and Aggression: Manual Blog Free Testosterone vs. Total Testosterone: Maximus Tribe The Influence of Testosterone on Aggressive Behaviour: Britannica The Vital Role of Testosterone in Muscle, Bone, and Brain Health: The Vitality Clinic Harvard Health: Testosterone—What It Does and Doesn’t Do

Testosterone Replacement Monitoring Targets and Their Management (Consult Your Physician Before Any Treatment Initiation, Cessation or Changes). These are not absolute values and should be taken into context with symptoms. We will discuss various blood test targets for those undergoing testosterone replacement therapy (TRT). It covers key health indicators such as total and free testosterone levels, hematocrit, PSA, estradiol, blood pressure, kidney and liver function, thyroid levels, iron and ferritin levels, and cholesterol. Each parameter includes a target range and suggestions for management if the results are outside the normal range. This comprehensive approach ensures that individuals on TRT can monitor their health effectively and make informed decisions with their healthcare provider.     Total Testosterone Test above 500 ng/dL If low or hypogonadal symptoms are not improved, increase the testosterone dosage. High T levels (over 1500 ng/dL) with high hematocrit, low HDL, and/or side effects may require dosage reduction.  Free Testosterone ≥ 2 % of total T If low, test for sex hormone-binding globulin. Higher TRT dose may increase free T by decreasing SHBG. Low SHBG may be present in diabetes. Hematocrit ≤ 53 % If high, donate blood or ask your doctor for therapeutic phlebotomy order. If low, investigate anemia or stop donating blood more than every 3 months. How to Lower High Hematocrit PSA ≤ 4 ng/mL If high, talk to your doctor about potential prostatic infection or a referral to a urologist. TRT is contraindicated if PSA is 4 ng/mL or greater. Estradiol (UltraSensitive Test) = 20- ? pg/mL Most men on TRT do not need to use an aromatase inhibitor (AI). Some physicians prescribe low dose AI for what they consider high estradiol. If low, higher testosterone dose and/or cessation of AI may be required. The lab range was derived from men with heart disease and low testosterone, so there is still debate on what the range should be for men on TRT since  0.3 to 0.4 % of testosterone aromatizes to estradiol, so men with high T due to TRT will have higher estradiol.  No upper range value has been determined for men on TRT. Studies have shown that for gynecomastia to occur, high estradiol in the presence of low T and high IGF-1 may be required. Read Estradiol In Men – Why Is It Important For Optimal Health And Fitness Performance and The Top 18 Things You Did not Know About Estradiol in Men Blood pressure ≤ 135/85 mmHg If high, weight loss, exercise, T dose reduction, and/or blood pressure medications may be needed. If too low, blood pressure medication dose needs to be reduced, electrolytes checked or hypoglycemia excluded. Estimated Glomerular Filtration Rate (eGFR) (kidney function) ≥ 60 mL/min/1.73 m2 If low, good hydration, use of blood pressure medications, and/or stopping offending oral supplements may improve eGFR. Exercise, high protein intake, creatine supplements, and higher muscle mass can also increase creatinine and decrease eGFR. If under 60, explore getting a Cystatin C test. Liver enzymes ≤ 1.2 x top value of reference range If high, stopping oral supplements can help. AST and ALT can increase with exercise but this is not clinically relevant. If high AST and ALT, test GGT and bilirubin to ensure no liver toxicity is present. TSH ≤ 2.5 U/mL If high, test for other thyroid tests included in a thyroid panel like free T3, free T4, and antibodies to detect hypothyroidism. Why Only Using TSH to Diagnose Hypothyroidism is Wrong Free T3 ≥ 3.7 pg/mL If low, hypothyroidism may be present. See comment on TSH. If high (>5 pg/mL), explore hyperthyroidism. Ferritin 55-270 ng/mL & Iron 55-160 micrograms/dL If low, reduce the frequency of blood donations or phlebotomies and supplement with iron until it is back to normal. If high, donate blood or get therapeutic phlebotomy. HDL ≥ 40 mg/dL The most difficult parameter to manage. Higher TRT doses decrease HDL. Niacin may help increase HDL but may cause flushing. Prolactin ( ≤ 30 nd/dL) Test if Total Testosterone is below 150 ng/dL before TRT to detect potential pituitary adenoma or other issues. High levels (> 30 ng/dL) may cause sexual dysfunction and galactorrhea in men (milk production)     Here are panels that include these tests: Discounted Labs Panels   Buy a testosterone test on DiscountedLabs.com