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Are you aware of the most common heavy metals that can ruin your health? No, not “heavy metal,” the famous rock genre, but heavy metals represented primarily by arsenic, lead, and mercury. Heavy metal testing is necessary to determine the levels of metals such as cadmium, lead, arsenic, and mercury in the body. Lead poisoning and mercury poisoning, among others, are significant concerns in the US and worldwide. It is a well-known fact that these heavy metals don’t offer any health benefits and might contribute to the development of different types of cancers. Table of Contents How to test for heavy metals? What are heavy metals? Are heavy metals dangerous? Why should I test for heavy metals? What heavy metals are tested using a blood and urine sample? How are samples collected? Are there any risks involved? Who should test for heavy metals? What are the most common types of heavy metals? Arsenic Mercury Sources of mercury Mercury treatment and prevention options Lead Sources of lead: Lead poisoning symptoms The lead-crime connection hypothesis Lead treatment and prevention options Cadmium Sources of cadmium include: Cadmium poisoning symptoms Cadmium treatment and prevention options Heavy metals summary What to do next? Essential tips to know before screening for heavy metals Order the heavy metal blood and urine test today! How to test for heavy metals? Testing for heavy metals can be done in various ways, and the most important ones are blood and urine tests. Taking blood and urine samples helps healthcare providers determine the levels of mercury, arsenic, cadmium, and lead in the body. Appropriate treatment options and dietary changes can be recommended to patients with high levels of heavy metals in the body to help them safely and progressively eliminate these unwanted substances. This article strives to inform readers about the adverse effects of heavy metals on the body. Keep reading to learn more about the symptoms of potential mercury poisoning, what foods contain high levels of arsenic, and how these metals can be excreted. What are heavy metals? Heavy metals occur naturally on earth and have high densities and atomic numbers. They have numerous applications and have been widely distributed worldwide in various formats. For example, batteries and metal alloys contain high levels of cadmium and mercury. Certain paints contain lead and other toxic elements. Pesticides, insecticides, and different types of glues also have heavy metals in their composition. Plastics and certain household items might contain arsenic and lead. Although the usage of heavy metals is carefully monitored nowadays, it is paramount to learn more about these dangerous substances and their potential effect on human health. Are heavy metals dangerous? If heavy metals accumulate in the human body in high quantities, they are dangerous and can develop different health conditions. For example: · Colds and flu · Chronic diarrhea · Anemia · Cardiovascular diseases · Respiratory illnesses · Neurodegenerative diseases This list is just a small sample of symptoms. Each heavy metal can trigger specific ailments and complications, depending on the organ it gets deposited in (such as the heart, kidney, liver, etc.). Why should I test for heavy metals? Heavy metals should be tested to assess their levels in the human body and undertake appropriate prevention/treatment options for eliminating them. These substances can be hazardous to human health, and they can create a lot of symptoms. Acute heavy metal poisoning can lead to impaired brain functioning, behavioral changes, and brain atrophy. In the worst cases, heavy metal poisoning can lead to life-threatening ailments. What heavy metals are tested using a blood and urine sample? The most common metals tested are arsenic, mercury, lead, and cadmium. Some metals, such as zinc, copper, chromium, and others, might be tested. How are samples collected? After ordering the heavy metal test, the patient receives an appointment at a nearby lab where a doctor can take blood samples. The healthcare provider will insert a small needle into an arm’s vein to collect blood for testing. The patient’s urine sample might also be required, collected into a 24-hour urine collection kit. The blood and urine samples are preserved in special containers to minimize exposure and contamination with other substances. Heavy metals can also be detected in hair and fingernails, although such testing procedures are rarer. Are there any risks involved? Minor bruising might occur when blood is collected from the arm, but it will pass in a couple of days, so testing for heavy metals is a risk-free experience. Who should test for heavy metals? Anyone who wants to measure his or her levels of heavy metals in the body qualifies for this test. The body can process a small number of heavy metals, but certain complications can occur when these substances are present in higher quantities in one's organism. Some people are more predisposed to heavy metal poisoning and are strongly encouraged to undertake this test. For example: · People who work in the construction industry · People who work in the mining industry · People who work in firing ranges or appliance repair shops · Factory workers who create metal alloys such as aluminum, bronze, and brass · People who handle batteries and paints regularly · People who live next to large industrial centers and waste disposal areas · People who live in very crowded cities What are the most common types of heavy metals? The list of heavy metals which can cause poisoning is broad. For example, cobalt, copper, barium, lithium, silver, zinc, and even gold poisoning are possible. However, arsenic, mercury, lead, and cadmium are the most widely distributed heavy metals. They are present in numerous household items and foods and usually produce the most health damage. Arsenic Arsenic divides into organic arsenic and inorganic arsenic. The United States is one of the largest consumers of arsenic worldwide. This heavy metal is usually excreted through urine and can be deposited in the spleen, liver, kidney, and lungs. Foods that contain arsenic Organic forms of arsenic include arsenobetaine, and these can be found in different types of foods such as: · Sardines · Oysters · Clams · Crabs and lobsters · Certain types of fish Trace amounts of arsenic can also be found in: · Beverages, including water · Rice · Vegetables · Fruit and fruit juices · Grains · Meat Inorganic arsenic can usually be found in the water extracted from wells. This heavy metal also gets in foods such as vegetables and fruit from contaminated soil. Medication containing arsenic was used to treat different types of skin conditions. The creams containing arsenic-caused skin cancer and were eliminated from pharmacies. Arsenic was also used to treat syphilis, but it was quickly replaced with powerful antibiotics, which are much safer. Arsenic poisoning symptoms When too much arsenic accumulates in the body, it causes different types of symptoms, including: · Seizures · Confusion · Headaches · Drowsiness · Fever · Diarrhea · Weakness · Muscle loss · Edema · Low blood pressure · Encephalopathy · Vomiting These symptoms usually appear approximately 2 to 8 weeks after exposure to high levels of arsenic. Other symptoms include abnormal darkening of the skin, white lines on nails, and inflammation of sensory nerves. Severe arsenic poisoning can lead to a burning sensation in the mouth, abdominal pain, muscle spasms, and hypotension. Occasionally, arsenic contamination can lead to jaundice-like symptoms such as yellowing eyes and skin. Arsenic poisoning treatment and prevention methods Before treating arsenic poisoning, it is necessary to gauge how much of this metal is present in the body. An arsenic blood or urine test is necessary; both tests can be ordered online. A healthcare provider interprets the results of the samples and determines if arsenic poisoning is a genuine concern for the patient. Remember that arsenic is excreted through urine, so most of it will be eliminated in a couple of days or weeks, depending on how much arsenic was present in the body in the first place. It has been discovered that selenium and vitamin E might help the body eliminate arsenic quicker, but more research is necessary. When it comes to prevention, there are several ways one can reduce his or her arsenic intake: · Consider water filtration systems. Buy a water cooler with an integrated reverse osmosis filter which can eliminate most arsenic and other heavy metals and impurities. · Consume seafood in moderation since most of it contains arsenic, particularly sardines · Get regular blood tests to measure arsenic levels and keep them under control · Consider soaking the rice for a couple of hours before cooking it, as this can eliminate most arsenic content · Chelation therapy might help Mercury Mercury poisoning can be another dangerous health problem as this heavy metal is present in multiple objects, tools, cosmetics, and applications people use daily. Mercury divides into metallic mercury, organic mercury, and inorganic mercury. It can be excreted through urine and feces, affecting the lung, skin, brain, and other vital organs. Sources of mercury Similar to arsenic, mercury can also be found in different types of seafood, such as: · Tilefish · Mackerel · Shrimp · Salmon Mercury can also get into the body from various other sources, such as: · Contaminated water · Contaminated air, particularly near power plants that burn mercury · Contaminated soil – mercury gets into the body through grains and vegetables Mercury poisoning symptoms Having too much mercury in the body can lead to multiple symptoms and health illnesses such as: · Constricted visual fields and even blindness · Joint problems · Mental fatigue · Nervousness and anxiety-like symptoms · Gastroenteritis · Muscle spasms · Insomnia · Weakness · Muscle loss Mercury can get into the body through vapors, creating a suite of respiratory problems such as: · Excessive coughing · Fever · Pneumonia This heavy metal tends to get deposited in red blood cells. Testing for mercury poisoning with a blood sample is the best way to discover if the mercury levels are dangerously elevated. Organic versions of mercury are particularly problematic as they can damage the central nervous system, causing mood swings, poor emotion control, and even mild personality changes in some patients. Mercury treatment and prevention options As mentioned earlier, mercury is excreted through urine and feces, and less than 1% can be eliminated through sweat. Getting rid of mercury isn’t a quick process. It can take approximately 6-12 months to eliminate 50% mercury content after a single exposure. However, there are some ways to excrete mercury faster. For example, one should increase his fiber intake to sustain two to three bowel movements per day. Another way of eliminating mercury from the body would be by increasing sulfur stores, which can be done using garlic. People might want to eat three or four cloves of garlic per day since the powerful anti-inflammatory properties of garlic help excrete mercury faster. It is best to use raw garlic instead of a garlic supplement. To prevent an unpleasant breath, it is possible to ingest the garlic without chewing it. Increasing the levels of antioxidants such as vitamin E and vitamin C can be beneficial for eliminating mercury more quicker. Lead Lead poisoning is equally dangerous and can contribute to numerous health complications. This heavy metal is present in gasoline, medical equipment, paints, batteries, metal alloys, and more. Lead is primarily deposited in bones, affecting individuals directly, depending on their age and health levels. It is excreted through urine and feces but can also be found in breast milk, saliva, and sweat. Sources of lead: Although the presence of lead in household items has been drastically monitored and reduced, this metal can still be found in: · Air and soil · Potable water · Different types of paints · Old toys and furniture items · Jewelry · Cosmetics and particular medicines · Ceramics Lead poisoning symptoms When the level of lead in the body increases to an alarming value, certain symptoms can appear such as: · Stomach problems · Anemia · Sleep disturbances · Muscle weakness · Neuropathy · Lack of appetite · Constipation In severe cases, lead poisoning can cause death, mainly if the quantity ingested has been high. These symptoms usually appear after three weeks from the moment of exposure. More severe symptoms can include: · Slurred speech · Mental retardation · Poor cognitive function · Brain damage · Encephalopathy · Convulsions and seizures · Change in behavioral patterns The lead-crime connection hypothesis During the 1960s and 1970s, lead was added to the gasoline used by vehicles and ended up in the atmosphere. Kids growing up in these decades were more exposed to lead (inhaling it from the air). Since this metal is known for causing behavioral patterns changes, researchers believe it provoked a substantial increase in the crime rate. However, a significant decrease in crime rate occurred between 1994 and 2004, which might be attributed to a drastic reduction in lead exposure among children. This happened mainly because fuels were manufactured without pollutants such as lead since the 1980s, and their quantity in breathable air was heavily reduced. Lead treatment and prevention options A urine specimen is required to determine the lead levels in a person’s body. Depending on the results, doctors can recommend specific treatment options to eliminate lead content and prevent additional exposure. Here are a few helpful prevention tips: · Water filtration systems can purify tap water and eliminate most lead content as well as other pollutants · Keeping a clean and dust-free house · Inspecting painted surfaces and addressing paint deterioration immediately · Washing hands often Eliminating lead from the body is a natural process that happens over time. Adults successfully eliminate lead, but kids are more vulnerable to its dangerous effects. When lead levels exceed 5mcg/dL, chelation therapy might be recommended as a treatment method for children and adults alike. Cadmium Cadmium poisoning poses serious health problems as this metal gets deposited primarily in the kidneys. It can be available near mining sites and places where waste is incinerated. Tobacco leaves also extract cadmium from contaminated soil, which gets in cigarettes. Smokers have a high risk of accumulating a large quantity of cadmium and other harmful toxins in their bodies. Cadmium is often found in batteries, fertilizers, and plastics. Sources of cadmium include: · Air (as vapors) and water (available in soluble forms) · Vegetables and plants (extracted from contaminated soil) · Seafood such as sardines and shellfish · Potatoes · Rice · Cocoa · Soybeans · Peanuts · Sunflower seeds · Meats It is important to note here that cadmium is present in trace amounts in the foods above. However, one should get tested for cadmium exposure using a urine sample to determine the levels of this heavy metal in the body. Cadmium poisoning symptoms This heavy metal can affect numerous organs in the body, and it is the source of many health complications. Symptoms include: · Fatigue and dizziness · Headaches and nausea · Abdominal pain · Vomiting · Pulmonary edema (particularly in smokers) · Rapid heartbeat for no reason · Impaired sense of smell Serious cases of cadmium exposure can cause significant kidney and liver damage. Cadmium is eliminated slowly from the body, which might take years. Cadmium treatment and prevention options There are several ways one can limit exposure to cadmium. These include: · Give up smoking and won't be exposed to second-hand smoking · Eat a diet containing sufficient amounts of iron · Keep a clean and dust-free home and workplace Similar to lead poisoning, chelation therapy might also help eliminate cadmium from the body quicker, but exposure should be drastically limited before beginning treatment. Heavy metals summary 1. Heavy metals don’t bring any health benefits, and they can cause severe complications in both adults and children 2. The most common types of heavy metals which can get into the body are arsenic, cadmium, mercury, and lead 3. Heavy metals are present almost anywhere, including the atmosphere, water, soil, foods, and electronics people use every day 4. Heavy metal poisoning can lead to numerous symptoms such as headaches, nausea, abdominal pain, confusion, dizziness, brain impairment and so on 5. Most heavy metals tend to be excreted through urine and feces, and they are deposited in bones and organs such as kidney, liver, and heart 6. Testing for heavy metals can be done using blood and/or urine sample 7. The body slowly eliminates heavy metals, but this process can be improved using chelation therapy 8. Children and newborns are more vulnerable to the dangerous effects of heavy metals in comparison with adults 9. Certain parts of Asia, such as Bangladesh, are significantly more exposed to heavy metals due to air and soil contamination 10. Hair and fingernails can also be sources of elimination of heavy metals What to do next? The next step would be to order a heavy metal test which consists of a urine and blood specimen. These will be sent to a laboratory for analysis, and the results will be received by email in a couple of business days. A professional healthcare provider helps the patient interpret the results and can make recommendations based on these results. The goal is to increase awareness regarding heavy metals and help people take control of their health. Essential tips to know before screening for heavy metals 1. Most seafood contains a decent amount of heavy metals, including arsenic and mercury. It is advised not to eat sardines, shellfish, oysters, or other types of seafood for up to 48 hours before being tested. 2. Avoid red wine approximately 72 hours before the test since this drink can significantly influence your results. Order the heavy metal blood and urine test today! Especially if you usually have some of the symptoms mentioned above, it is paramount to take this test and assess the levels of heavy metals in your body. Order the heavy metals test today, and you’ll have more peace of mind.   FIND OUT IF YOU HAVE HEAVY METAL POISONING BY GETTING THESE TESTS: Click here  

Table of Contents What are Estradiol and Aromatase? When aromatase is unbalanced, estradiol becomes an issue Low estrogen levels in men, not testosterone increases risk of heart disease Androgen deprivation therapy can cause cognitive decline Does estradiol restore cognitive function during ADT? Should high estradiol levels be treated? What are Estradiol and Aromatase? Estradiol is a form of the female hormone estrogen. Although estradiol production is typically considered a female concern, men also need to maintain healthy levels of this hormone for optimal health. Since men lack ovaries (where most estradiol is produced in women), estradiol in men is created by a process that uses an enzyme called aromatase (1) in testicles, liver and fat cells. Aromatase converts a very small portion of testosterone levels into estradiol, and health problems can arise when aromatase levels are too high or too low (1). When aromatase is unbalanced, estradiol becomes an issue As men age, they can experience excess aromatase activity, raising estradiol levels and reducing testosterone to unhealthy levels. Low T levels will adversely impact quality of life by reducing libido, ability to maintain an erection, mood, and muscle mass, among other health factors (2). However, when the body produces too little aromatase, men can experience other, potentially serious health problems. Men with diminished aromatase levels will have an estradiol deficit, which can create problems similar to low-T; diminished sex drive, loss of bone mass, and increased body fat (3). Men on testosterone replacement therapy (TRT) taking higher doses of aromatase inhibitors can also experience estradiol deficit. Let’s look at recent studies finding that low estradiol can play a critical role in increasing the risk of cognitive decline and increase the odds of experiencing cardiovascular disease. Low estrogen levels in men, not testosterone increases risk of heart disease A study led by Elaine Yu, MD, MSc, addresses the suspicion held by many medical professionals that testosterone can promote cardiovascular disease in men, and that estradiol provides protection against it (4). The researchers sought to determine whether it was estradiol or testosterone that regulated men’s cardiovascular risk factors by comparing two groups whose hormone levels were changed using a combination of medications (4). They looked at 400 healthy men, between the ages of 20 and 50. Study participants were weighed, had fasting blood tests for markers of heart disease and diabetes, and also had a thigh scan using quantitative computed tomography (CT scan) to measure muscle fat content before and after the study (4). Yu’s team found that while higher levels of testosterone reduced these men’s levels of healthy (HDL) cholesterol, changes in estradiol levels had no effect at all on HDL(4). However, they also discovered that low estradiol levels did increase the markers for diabetes, like increased insulin resistance, increased fat in the muscles, and higher fasting blood sugar levels(4). Diabetes is a major risk factor for heart disease (5). Additionally, the study found that neither estradiol nor testosterone affected the levels of LDL (unhealthy) cholesterol. According to Yu, these findings indicate that in men, it’s higher testosterone levels combined with lower estradiol levels that can worsen cardiovascular risk factors, somewhat explaining differences in the incidence of heart disease between men and women. Some studies have shown that it is the ratio of testosterone to estradiol that is important, not just the level of each of those hormones. As testosterone increases with TRT, so does estradiol to balance the effects of testosterone on lipids, mood and insulin action. Androgen deprivation therapy can cause cognitive decline Androgen deprivation therapy (ADT) is an often used method to slow the growth of prostate cancer. It’s also used for men transitioning to women (6, 7). ADT is typically prescribed on an open-ended (no fixed period) basis to help treat advanced prostate cancer. An estimated 44 percent of men with prostate cancer will undergo ADT at some point as part of a strategy to slow tumor growth (6). ADT therapy is used specifically to block the male hormones, particularly testosterone, from stimulating prostate cancer cell growth. Research has confirmed that ADT can cause significant cognitive decline in women with breast cancer (8), but few studies have investigated cognitive impairment following ADT for men being treated for prostate cancer. Using formal tests, scientists recently compared the cognitive ability of 58 prostate cancer patients receiving androgen deprivation therapy to 84 prostate cancer patients who did not receive ADT, and 88 cancer-free men (9). They found that those treated with ADT were 70 percent more likely to develop cognitive impairment after six months, and over twice as likely to have significant cognitive impairment after one year(9).   Does estradiol restore cognitive function during ADT? A 2018 study published in Current Neuropharmacology has examined whether estradiol supplementation is an effective way to prevent this side effect (9). Researchers performed a literature search using PubMed and Google Scholar to identify studies on this topic and discover any evidence that estradiol supplementation has a cognitive benefit for men on ADT. They examined studies involving the effects of estradiol treatment on cognitive function in three androgen-deprived male populations; prostate cancer patients, male-to-female transsexuals, and castrated male animals (9). A review of the literature found that while some studies show that estradiol supplementation resulted in cognitive improvement (especially in spatial ability), They couldn’t determine (9): Whether estradiol will improve cognition after long-term ADT How early or delayed estradiol treatment post-castration will affect cognition If estradiol affects memory retention They conclude that for androgen-deprived males, there is some evidence that estradiol supplementation may improve both verbal and visual memory (9). However the variability between the reviewed studies resulted in significant inconsistencies, making further study necessary to determine what estradiol treatment protocol can best maximize cognitive improvement for men using ADT (9). Should high estradiol levels be treated? Men on testosterone replacement therapy can experience an increase in estradiol that can sometimes reach clinically elevated levels (10). A study published in the Journal of Sexual Medicine (11) looks at the phenomenon of increased estradiol levels in men undergoing TRT to discover whether high estradiol levels in this population should be treated. Researchers comprehensively reviewed the published literature on the role of estradiols in male sexual function and testosterone deficiency to answer this question. The study findings reveal that (11): Although estradiol have been used at pharmacologic doses to suppress serum testosterone, there is no evidence that naturally occurring elevations of estradiol will cause a reduction in testosterone levels Absent testosterone deficiency, study findings suggest that elevated estradiol levels don’t seem to be harmful. Once again, monitoring and treating the ratio of testosterone to estradiol may be more important than either hormone alone. Estradiol could help maintain some sexual function in castrated men Given the evidence uncovered by this review study, researchers report that, although further research is needed, the existing evidence doesn’t support the treatment of elevated estradiol for men on testosterone therapy (11). WATCH LECTURE ABOUT ESTRADIOL IN MEN    BUY YOUR SENSITIVE ESTRADIOL TEST   References 1) Stocco, Carlos. “Tissue Physiology and Pathology of Aromatase.” Steroids 77.1-2 (2012): 27–35. PMC. Web. 11 June 2018. 2) Araujo, Andre B., and Gary A. Wittert. “Endocrinology of the Aging Male.” Best practice & research. Clinical endocrinology & metabolism 25.2 (2011): 303–319. PMC. Web. 11 June 2018. 3) Bulun, Serdar E. “AROMATASE DEFICIENCY.” Fertility and sterility 101.2 (2014): 323–329. PMC. Web. 11 June 2018. 4) Men's heart disease risk linked to high testosterone and low estrogen. The Endocrine Society. 5) Zhang PY. Cardiovascular disease in diabetes. Eur Rev Med Pharmacol Sci. 2014;18(15):2205-14. 6) Perlmutter, Mark A, and Herbert Lepor. “Androgen Deprivation Therapy in the Treatment of Advanced Prostate Cancer.” Reviews in Urology 9.Suppl 1 (2007): S3–S8. Print. 7) Unger, Cécile A. “Hormone Therapy for Transgender Patients.” Translational Andrology and Urology 5.6 (2016): 877–884. PMC. Web. 11 June 2018. 8) Wu, Lisa M., and Ali Amidi. “Cognitive Impairment Following Hormone Therapy: Current Opinion of Research in Breast and Prostate Cancer Patients.” Current opinion in supportive and palliative care 11.1 (2017): 38–45. PMC. Web. 11 June 2018. 9) Wibowo E. Cognitive Impacts of Estrogen Treatment in Androgen-Deprived Males: What Needs to be Resolved. Curr Neuropharmacol. 2017;15(7):1043-1055. 10) Tan RS, Cook KR, Reilly WG. High estrogen in men after injectable testosterone therapy: the low T experience. Am J Mens Health. 2015 May;9(3):229-34. doi: 10.1177/1557988314539000. Epub 2014 Jun 13. 11) Ravi Kacker, Abdulmaged M. Traish, Abraham Morgentaler. Estrogens in Men: Clinical Implications for Sexual Function and the Treatment of Testosterone Deficiency. The Journal of Sexual Medicine. (2012): Volume 9, Issue 6, Pages 1681–1696

Table of Contents What is CHD and Why it is Important to Monitor and Treat? What is Chronic Kidney Disease? What Causes Chronic Kidney Disease? What are the Five Stages of Chronic Kidney Disease? What are the Symptoms of Chronic Kidney Disease? How is Chronic Kidney Disease Diagnosed? How to Treat Chronic Kidney Disease? How Fast Does Chronic Kidney Disease Progress? How Can Chronic Kidney Disease be Reversed? Can Chronic Kidney Disease Cause UTI? How Long Can You Live with Chronic Kidney Disease? CMP - Comprehensive Metabolic Panel Aldosterone, Serum Cystatin C with EGFR Blood Test Electrolyte Panel Uric Acid (Serum) Urinalysis Be kind to your kidneys. Get tested today! What is CHD and Why it is Important to Monitor and Treat? Chronic kidney disease (CKD) is a much larger health problem in the U.S. than many of you reading this may realize, which is why we’re going to answer all of your burning questions having to do with chronic kidney disease, including the stages, the symptoms, and the treatment options.   According to the Centers for Disease Control and Prevention (CDC)[1], the numbers are a little overwhelming:   15 percent of U.S. adults have chronic kidney disease (37 million people) Nine out of 10 adults in the U.S. don’t know they have CKD One out of two adults in the U.S. with very low kidney function who are not already on dialysis don’t know they have chronic kidney disease   What’s the greatest takeaway from these three statistics? People who are at risk of getting CKD are not getting tested for it, which has negative long-term consequences.   Other important facts according to the CDC on chronic kidney disease include:   Chronic kidney disease is more common in people aged 65 years or older (38 percent) than in people aged 45–64 years (13 percent) or 18–44 years (7 percent) Chronic kidney disease is more common in women (15 percent) than men (12 percent) Chronic kidney disease is more common in African Americans (16 percent) than in whites (13 percent) or Asians (12 percent). Around 14 percent of Hispanics have chronic kidney disease   Now that you know the facts and understand the severity of CKD, let’s answer some important questions about the disease.   What is Chronic Kidney Disease?   CKD is a condition in which the kidneys gradually lose their ability to properly function. The kidneys can become damaged over time and this damage can lead to kidneys that don’t clean/filter a person’s blood as well as they should.   When the kidneys aren’t able to perform their job duties, this creates waste and water buildup in the body. As you might expect, this contributes to other health problems as this waste and water accumulate.   The biggest problem with chronic kidney disease is the lack of symptoms initially, as they tend to be more gradual. We’ll get into some of those symptoms in a minute.   What Causes Chronic Kidney Disease?   The two main causes of chronic kidney disease, according to Kidney.org[2], are diabetes and high blood pressure.   Diabetes occurs when a person’s blood sugar levels are too high. When this happens, the person can experience damage to their organs and blood vessels.   High blood pressure, or hypertension, occurs when the pressure in the walls of the blood vessels increases to dangerous levels. High blood pressure can lead to increase risks of heart attack, stroke, and, of course, chronic kidney disease.   Other causes or risk factors include:   A family history of kidney problems Glomerulonephritis – a group of diseases that cause inflammation and damage to the kidneys’ filtering capabilities Polycystic kidney disease – an inherited disorder that causes cysts to develop in the kidneys   What are the Five Stages of Chronic Kidney Disease?   They are five stages of CKD. According to Fresenius Kidney Care[3], these are the characteristics of each stage:   Stage 1 – Kidney damage that still allows for normal kidney function. Stage 2 – Kidney damage with a mild loss of function. Stage 3 – Broken up into two stages, 3a includes mild to moderate loss of kidney function; 3b includes moderate to severe loss of kidney function. Stage 4 – Severe loss of kidney function. Stage 5 – Kidney failure, which will require dialysis and/or a kidney transplant.   What are the Symptoms of Chronic Kidney Disease?   Unfortunately, the disease process can take years before symptoms are present, and this is true for CKD. Chronic kidney symptoms, according to Kidney.org, include:   Fatigue and loss of energy Difficulty with concentration and focus Lack of appetite Difficulty sleeping Muscle cramping at night Swelling in feet and/or ankles Puffiness around the eyes Itchy, dry skin Frequent urination, especially at night   Please remember, these symptoms can take years to develop. By the time you experience symptoms, you could be further along in the disease process than you might imagine. Symptoms for CKD don’t show up quickly like email. They take their time, like Pony Express.   How is Chronic Kidney Disease Diagnosed?   Diagnosis of CKD is done using a combination of the following:   A thorough medical history A physical examination A urine dipstick test – measures pathological changes to a person’s urine Blood testing, like measuring a person’s serum creatine level   There is some dispute today whether the creatinine test is really the best option, as the Cystatin C test may be better for muscular men.   Anyone who has the risk factors for chronic kidney disease should get tested and this includes older Americans who may not have diabetes or high blood pressure and those individuals in a higher-risk population, like African Americans, Hispanic Americans, Asian Americans, Pacific Islanders, and Native Americans.   How to Treat Chronic Kidney Disease?   Chronic kidney disease treatment is more disease management than anything else since the damage cannot be fixed, according to The American Kidney Fund.[4]   For this reason, it’s important to stop the damage from getting worse. To this end, there are several treatment protocols that The American Kidney Fund recommends:   Stabilize your blood sugar, especially if you have diabetes Maintain a healthy blood pressure Eat a healthy diet – low salt, low fat Exercise at least 30 minutes each day or engage in other physical activities Maintain a healthy weight for your body type and height Do not smoke or use tobacco products Limit your alcohol consumption Ask your doctor what medications may help control your CKD   The point worth remembering is this: You can catch CKD early and make the positive changes listed above or let your kidneys eventually fail. For this reason, prevention is always going to trump treatment, and this is very true when it comes to chronic kidney disease.   If you’re interested in preventing chronic kidney disease, simply follow those recommendations above before CKD develops.   How Fast Does Chronic Kidney Disease Progress?   As you’ve learned already, chronic kidney disease can take years to develop before symptoms are present. However, according to Randy Chen, MD[5], a practicing nephrologist with San Mateo County, the progression of CKD depends on other factors.   Both the cause of your chronic kidney disease and your current stage are important. The results of your blood tests – which can help your doctor determine the trends in your kidney health – are equally important. And finally, Chen points out that while the progression can be slow, those in poorer health will experience faster progression of CKD.   How Can Chronic Kidney Disease be Reversed?   Unfortunately, CKD cannot be reversed. However, it can be managed. The first step is to get tested and determine if you have chronic kidney disease. All subsequent steps involve the management/treatment options we listed above in the chronic kidney disease treatment section.   Can Chronic Kidney Disease Cause UTI?   UTI is short for urinary tract infections. Germs and bacteria can get into the urinary tract and multiply. The result is usually a combination of swelling, redness, and pain. The greater problem is that if left untreated, it can get worse and cause a more serious infection. However, it does not appear that CKD causes UTIs.   How Long Can You Live with Chronic Kidney Disease?   According to LifeOptions.org, “how long you can live with CKD depends on your age, other health problems, and how involved you become in your care.”   Most people who have CKD will never have their kidneys fail and many people who do have kidney failure can still live for decades afterward with dialysis or a kidney transplant.   Advances in healthcare have come a long way. There are better drugs for chronic kidney disease, more knowledge about the disease, and better dialysis machines helping people manage their CKD.   However, according to LifeOptions.org[6], the most important factor in determining how your CKD will progress is you. If you take responsibility for your health and make the necessary changes, you can live well with chronic kidney disease. And do you know where that personal responsibility begins? Getting tested!   We’re going to end this post with words of advice from Fresenius Kidney Care:   “Getting tested to check your kidney health is critical to your current and future well-being. Whether you and your doctor are seeking a diagnosis or monitoring how well your treatment plan is working, acting early is always best. For CKD, the sooner your doctor can confirm a diagnosis, the earlier you can get started on an effective treatment plan to help preserve kidney function and slow progression.”   If you’re interested in getting tested for chronic kidney disease, Discounted Labs has six laboratory tests that can measure your kidney function:   CMP - Comprehensive Metabolic Panel   The comprehensive metabolic panel or chemical screening, (CMP) is a panel of 14 blood tests which serves as an initial medical screening tool to review overall health. The CMP functions as a check for kidney function, liver function, and electrolyte and fluid balance.   Aldosterone, Serum   Aldosterone (ALD) is one of a group of connected hormones. They form the renin-angiotensin-aldosterone system; this system is activated when there is a decrease in blood flow to your kidneys following a drop in blood volume or blood pressure such as during heavy bleeding, or sodium levels fall below healthy levels.   Cystatin C with EGFR Blood Test   The cystatin C test (which also includes estimated creatinine clearance eGFR) can be done along with creatinine or creatinine clearance test in cases where those tests aren’t appropriate. Since the concentration of cystatin C in the blood will not change due to infection or inflammation and isn’t affected by body weight, drugs, or diet - cystatin C level could be a more reliable indicator of kidney health than creatinine.   Electrolyte Panel   The electrolyte panel includes carbon dioxide, chloride, potassium, and sodium.   Uric Acid (Serum)   Uric acid is a product produced by the body after the purines in many foods undergo the digestive process and are broken down inside the body. After this breakdown process, the uric acid travels through the bloodstream into your kidneys, and most are actually eliminated through the urinary tract via urination. Excess uric acid may indicate CKD.   Urinalysis   The Urinalysis test screens for a variety of conditions including urinary bladder disease, kidney disease, and diabetes. Many systemic illnesses can affect results and significant deviations from the normal range may require further evaluation by your physician.   Be kind to your kidneys. Get tested today!   Sources & References   1 Centers for Disease Control and Prevention, Chronic Kidney Disease in the United States, 2019 2 Kidney.org, Chronic Kidney Disease (CKD) Symptoms and Causes 3 Fresenius Kidney Center, Diagnosis and Testing for Chronic Kidney Disease 4 The American Kidney Fund, Chronic kidney disease (CKD) 5 Randy Chen, MD, The American Kidney Fund 6 LifeOptions.org, Learn About Kidney Disease FAQ

Hyponatremia is when the amount of sodium in the blood is below what it should be. Your nerves and muscles, as well as the balance of water in your body, depend on salt. Normal sodium levels in the blood are between 135 and 145 milliequivalents per liter (mEq/L). When your blood sodium level drops below 135 mEq/L, you have hyponatremia. When your blood doesn't have enough salt, extra water goes into your cells, making them swell. This can be dangerous, especially in the brain, because the brain can't grow bigger than the head. Table of Contents Introduction Causes of Hyponatremia Overconsumption of Fluids Medical Conditions Certain Medications Hormonal Imbalances Elevated Vasopressin Levels Symptoms of Hyponatremia Diagnosing Hyponatremia Blood Tests Urine Tests Further Investigations Treating Hyponatremia Limiting Fluid Intake Medication Modification Intravenous Fluids Treating Underlying Disorders Hormone Replacement Therapy References Footnotes Introduction Hyponatremia is a common electrolyte imbalance characterized by abnormally low levels of sodium in the blood (less than 135 mmol/L). This imbalance can result in a myriad of symptoms and complications. In this article, we delve into the potential causes, symptoms, diagnostic procedures, and potential treatment options for hyponatremia. Causes of Hyponatremia Several factors can cause hyponatremia, including: Overconsumption of Fluids An excessive intake of fluids, especially water, can dilute the sodium concentration in the blood, leading to hyponatremia1. Medical Conditions Diseases such as kidney disease, heart failure, liver cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) can disrupt the normal sodium balance in the body2. Certain Medications Certain medications, including some pain medications, antidepressants, antiepileptic drugs, and diuretics, can cause hyponatremia3. Hormonal Imbalances Conditions like adrenal insufficiency, hypothyroidism, and low cortisol levels can disturb the body's electrolyte balance4. Elevated Vasopressin Levels Excessive amounts of the hormone vasopressin, also known as the antidiuretic hormone (ADH), can lead to increased water retention and decreased sodium levels5. Symptoms of Hyponatremia The severity of hyponatremia symptoms and the rate at which they develop depend on the extent and speed of sodium loss. Symptoms may include: Nausea, vomiting, and loss of appetite Headaches, confusion, and disorientation Seizures, muscle cramps, and weakness Fatigue, lethargy, and irritability Swelling of the extremities, also known as edema Decreased urine output and increased thirst In severe cases, hyponatremia can be life-threatening. Diagnosing Hyponatremia An accurate diagnosis of hyponatremia requires a comprehensive evaluation, including medical history, physical examination, and laboratory testing. Blood Tests Tests such as complete blood count (CBC), serum sodium levels, blood urea nitrogen (BUN), creatinine, and liver function tests can evaluate electrolyte imbalance and organ function6. Urine Tests Urinalysis and urine electrolyte analysis can help determine the underlying cause of hyponatremia, such as SIADH or kidney dysfunction7. Further Investigations In some cases, additional tests, like thyroid function tests, cortisol levels, and adrenal function tests may be conducted to uncover hormonal imbalances8. Treating Hyponatremia The treatment for hyponatremia depends on the underlying cause, severity of symptoms, and rate of sodium decline. Common treatment methods include: Limiting Fluid Intake In mild cases of hyponatremia caused by excessive fluid intake, limiting fluid consumption is often enough to restore sodium balance9. Medication Modification If hyponatremia is induced by medication, adjusting the dosage or switching to a different prescription may be necessary10. Intravenous Fluids In severe cases, intravenous infusion of hypertonic saline solution can help restore sodium levels and reduce symptoms11. Treating Underlying Disorders Addressing the underlying medical disorders, such as heart failure or liver cirrhosis, is crucial to effectively manage hyponatremia12. Hormone Replacement Therapy In cases where hormonal abnormalities are present, hormone replacement therapy might be used13. Find out your sodium level at DiscountedLabs.com Buy the CMP test.       References Footnotes Adrogué HJ, Madias NE. Hyponatremia. N Engl J Med. 2000;342(21):1581-1589. ↩ Upadhyay A, Jaber BL, Madias NE. Incidence and prevalence of hyponatremia. Am J Med. 2006;119(7 Suppl 1):S30-S35. ↩ Clayton JA, Rodgers S, Blakey J, Avery A, Hall IP. Thiazide diuretic prescription and electrolyte abnormalities in primary care. Br J Clin Pharmacol. 2006;61(1):87-95. ↩ Furst H, Hallows KR, Post J, Chen S, Kotzker W, Goldfarb S, Ziyadeh FN, Neilson EG. The urine/plasma electrolyte ratio: a predictive guide to water restriction. Am J Med Sci. 2000;319(4):240-244. ↩ Ellison DH, Berl T. Clinical practice. The syndrome of inappropriate antidiuresis. N Engl J Med. 2007;356(20):2064-2072. ↩ Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, Decaux G, Fenske W, Hoorn E, Ichai C, Joannidis M, Soupart A, Zietse R, Haller M, van der Veer S, Van Biesen W, Nagler E. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol. 2014;170(3):G1-G47. ↩ Bartter FC, Schwartz WB. The syndrome of inappropriate secretion of antidiuretic hormone. Am J Med. 1967;42(5):790-806. ↩ Decaux G, Musch W. Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone. Clin J Am Soc Nephrol. 2008;3(4):1175-1184. ↩ Verbalis JG, Goldsmith SR, Greenberg A, Schrier RW, Sterns RH. Hyponatremia treatment guidelines 2007: expert panel recommendations. Am J Med. 2007;120(11 Suppl 1):S1-S21. ↩ Sterns RH, Nigwekar SU, Hix JK. The treatment of hyponatremia. Semin Nephrol. 2009;29(3):282-299. ↩ Sterns RH, Hix JK, Silver S. Treating profound hyponatremia: a strategy for controlled correction. Am J Kidney Dis. 2010;56(4):774-779. ↩ Schrier RW. Body water homeostasis: clinical disorders of urinary dilution and concentration. J Am Soc Nephrol. 2006;17(7):1820-1832. ↩ Gross P, Reimann D, Henschkowski J, Damian M. Treatment of severe hyponatremia. J Am Soc Nephrol. 2001;12 Suppl 17:S25-S29. ↩

Acne is one of the most annoying skin problems people can develop throughout their lifetime. It basically consists of small lesions, pimples, irritation, redness, and other skin imperfections. Acne can spread over the forehead, neck, face, shoulders and chest area. Although it's commonly believed that teenagers get the most acne problems, this skin condition can be prevalent in people of all ages. Acne can also develop as a side effect of taking exogenous testosterone, so even if you're well into your forties or fifties, you might still get acne at some point in your life. Are you wondering if TRT and acne correlate with each other? There are a handful of possible side effects of TRT (testosterone replacement therapy). While most side effects of TRT are manageable, if not avoidable, some can be quite serious if the use of exogenous hormones is abused or if simple genetic factors are not correctly dealt with accordingly. Then there are those potential side effects of TRT that are far less serious, but ones we might place in the vanity category. One of these side effects of TRT is acne. Acne is something most grown men do not concern themselves with; after all, we all think of it as an irritation long since left behind in adolescence. However, for some men, the use of exogenous testosterone can cause this childhood enemy to rear its ugly head once again. Before we dive into this particular side effect of TRT, there is a significant genetic factor we would be remised if we left out. Those who are naturally predisposed to acne are at the most risk. Those who never had severe acne issues in their youth will unlikely experience an issue while on TRT. Sure, anyone can get a zit even in adulthood. You may find a few pop up here and there on TRT that you normally wouldn’t get. But as it pertains to a serious issue, the genetically predisposed are at the highest risk. Table of Contents Testosterone and Acne: The Process Acne or Folliculitis? How to Differentiate? Avoiding TRT Acne Through Hygiene How to Deal With TRT-related Acne TRT and Acne: Other Treatments What Causes Acne? And how to Prevent It? Latest FDA-Approved Acne Products: Sarecycline Altreno Onextron Differin Gel Aczone Gel Trifarotine Cream Picking the Best Acne Treatment References Testosterone and Acne: The Process Testosterone is a hormone that converts to an even more powerful hormone known as dihydrotestosterone (DHT). Many studies have shown DHT to be upwards of five times more powerful than the testosterone hormone. DHT is an extremely important hormone in the male body. It is imperative to our sexual health if for no other reason. DHT also causes the body to produce more oil, leading to oily skin and more oil soaking into your pores, resulting in acne. However, blocking DHT is not a good idea since it has many benefits for men. It’s a relatively simple process, but one that can be quite bothersome if not embarrassing. Your health has greatly improved through TRT; you’re now in better shape, leaner, and more muscular, and your sex drive is back to where it used to be, but your face looks like that of a 14-year-old boy. If this doesn’t sound desirable, that’s because it’s not. However, there’s also some very good news: acne related to TRT is more than manageable if not outright avoidable. Check the DHT test on DiscountedLabs.com. Acne or Folliculitis? How to Differentiate? Sometimes what we think is acne isn't. Some men on testosterone replacement therapy (TRT) develop red bumps on their skin when on the hormone. Some doctors have found out that it is folliculitis. You need to see a dermatologist who can accurately diagnose this problem, so do not assume it is just acne.  Folliculitis is the infection and inflammation of one or more hair follicles. The condition may occur anywhere on hair-covered skin. The rash may appear as pimples that come to white tips on the face, chest, back, arms, legs, buttocks, or head. Eosinophilic folliculitis is an itchy rash with an unknown cause that is most common among individuals with HIV, though it can occur in HIV-negative individuals where it is known by the eponym Ofuji disease.  EF consists of itchy red bumps (papules) centered on hair follicles and typically found on the upper body, sparing the abdomen and legs. The name eosinophilic folliculitis refers to the predominant immune cells associated with the disease (eosinophils) and the involvement of the hair follicles. Folliculitis can be treated with minocycline, UV light, retionic acid washes, and topical corticoid steroids. Avoiding TRT Acne Through Hygiene The best thing you can do to prevent TRT related acne is also the simplest: hygiene. Washing your hands and face multiple times a day will have a positive effect. You can choose not to, but you’re only hurting yourself. This is something you should be doing even if you’re not on TRT. Carry a small towel with you each day and keep your face dry, but let’s not stop there. Acne can also easily appear on our shoulders, back, and chest, so it will be important to keep our entire body clean, especially if we’re predisposed to acne. Any time you become sweaty, such as after a gym session, working outside, or any other activity that leaves you a little sweaty, take a shower and put on a clean shirt. If you can’t take a shower immediately, let’s at least put on a fresh, clean, dry shirt and shower as soon as we can. Along with simply being hygienic, there are some good soaps, anti-acne soaps you may want to consider. Any soap containing the ingredients Benzoyl Peroxide or Salicylic acid will be worth a try. Simply wash your troubled areas with this anti-acne soap, rinse and repeat each time you shower. How to Deal With TRT-related Acne Want to get rid of pimples or prevent your TRT treatment from causing an outbreak? Here are a few things you can try: - Use Accutane -- Accutane, or isotretinoin, is one of the most potent prescription treatments to cure acne. It's usually used to treat cystic acne, which is a much more serious form of acne that is likely to cause scarring. The treatment is effective in up to 85% of cases. Taking 40 mg of Accutane every day for a week can do wonders for your acne. However, be aware that the medication does come with side effects, and it may lower testosterone levels and have psychiatric side effects is some people. Consult your physician before mixing TRT and Accutane. - Use Sporanox -- Sporanox, or itrconazole, is another useful medication to try as a means of curing your acne. It is an anti-fungal drug that may be able to kill off the P. acne bacteria that is increasing your skin cell turnover rate, thereby increasing your risk of clogged pores. Once again, check with your doctor before mixing TRT and Sporanox. - Try Vitamin B5 -- Vitamin B5, or pantothenic acid, is needed by your body in order to produce CoEnzyme A (CoA). This enzyme helps to oxidize (burn) fatty acids, particularly in your skin. If you don't have enough of this CoA, your body won't be able to eliminate the fatty acids produced by an increase in DHT, so the skin oil will increase and lead to acne. By taking Vitamin B5, you give your body what it needs to keep the fatty acid production under control. - Try anti-acne soap -- There are a number of anti-acne soaps available at every pharmacy and supermarket in the country. These soaps are often made with Benzoyl Peroxide or Salicylic acid, two highly effective anti-acne treatments. Ideally, you should shower after a heavy workout, and use the soap to wash your face and any body parts where there is an acne breakout. Topix Benzoyl Peroxide is a body wash worth trying. - Try zinc -- Zinc is one of the most important minerals for a healthy body. It plays a vital role in many important internal functions, not the least of which is your body's immunity to disease. But how can it help to protect against acne? Zinc ensures that your bloodstream carries sufficient Vitamin A to your skin, and it helps to regulate the cellular apoptosis (death) of your skin cells. By ensuring that your skin cells die at a healthy rate, zinc essentially prevents the buildup of dead skin cells that soaks up skin oil to clog your pores. - Get out -- Your body NEEDS sunlight in order to produce Vitamin D, one of the vitamins that play a role in fatty acid oxidation. However, be warned: too much sunlight can dry out your skin, causing it to produce even more oil. No more than 30 minutes of sunlight per day is needed to encourage healthy Vitamin D production. If your acne is the result of the TRT, you may want to consider reducing the dose of testosterone. This can reduce the amount of DHT produced in your body, preventing acne. However, this is something you should discuss with your doctor. You can also discuss other useful treatments for dealing with the TRT-related acne. TRT and Acne: Other Treatments If your acne is severe due to TRT, there are several medications you may want to consider. These medications can have a positive effect, but they are not without their own potential risk. One of the most commonly used medications for the treatment of acne is Accutane. Accutane has a success rate of upwards of 85%. However, while it’s generally used for severe cases, such as cystic acne, some TRT users may find it to be the right course of action. The most common side effect many users concern themselves with is that the drug can lower testosterone levels. However, in your case, you’re already using exogenous testosterone. Your natural production is already subpar. This side effect of Accutane should not be an issue for you. There are other drugs, such as Sporanox, an anti-fungal medication that some may find helpful. A full lost of FDA approved medications for treating acne that may be worth consideration if this particular side effect of TRT manifest: Trifarotene Cream Aczone Gel Differin Gel Onextron Altreno Sarecycline (Seysara) Many natural remedies are available that many may find to be effective, not to mention simply healthier. Three of these remedies include B5, zinc and vitamin D. Some may find B5 useful due to its ability to produce Coenzyme A (CoA). This enzyme will help in the oxidization of fatty acids, primarily in the skin, burning the fatty acids that increase due to DHT. Then we have the overall fantastic mineral zinc. This mineral plays several important roles in the human body. For our purposes here, zinc helps carry vitamin A to the skin. This greatly aids in preventing the buildup of dead skin, which can clog our pores and lead to acne. Finally, vitamin D: vitamin D, while it’s not the only source of oxidizing fatty acids, it is one that plays an important role. A mere thirty-minutes of sunlight per day will give you all the vitamin D you need to meet the desired end.  If the use of the various vitamins and minerals discussed doesn’t do the trick, if you’ve found prescription medications to be lacking for your needs, you may need to consider an alternative. This alternative action may be as simple as lowering your testosterone dose. You may only need to lower the total amount per injection and not the weekly dose. For example, if you’re injecting a total of 200mg per week, consider splitting it into 100mg twice a week. If you’re already following such a protocol, you could split the total milligrams injected per week into three or even four smaller injections. If one is following a sub-Q protocol, although injections will be frequent, they will be far less bothersome than 3-4 Intra-muscular injections per week. If that still doesn’t do the trick or you’re simply not interested in multiple injections per week, lowering the total dose of testosterone so that there’s less testosterone to convert to DHT may be your only option. What Causes Acne? And how to Prevent It? Acne develops when subcutaneous sebaceous glands on the skin get blocked or filled with excessive amounts of sebum. Sebum is a waxy-like substance which protects the skin. When too much sebum is secreted, the sebaceous glands can get infected which leads to acne. Contrary to popular belief, acne isn't really caused by a poor diet consisting of fatty foods. Acne might develop as a result of reaching puberty or when a person is getting through a great deal of stress. Taking advantage of testosterone replacement therapy (TRT) can also trigger acne as a side effect. This might be caused by an excessive amount of estradiol present in the bloodstream. Preventing acne is also quite difficult, but you can manage it much better thanks to a few products recently approved by the FDA. These creams and gels are designed to reduce the effects of acne and prevent it from ruining your image and the aesthetics of your skin. Let's take a closer look at some of these products and see what are their benefits! They can be used by TRT patients to mitigate the effects of acne on their face, chest, and shoulders. Latest FDA-Approved Acne Products: As a rule of thumb, keep in mind that not everyone who goes through TRT gets acne as a side effect. A plethora of patients doesn't experience skin problems at all, ever. Others might get mild acne on their faces and shoulders which can go away on its own. In some rare cases, the acne might be more severe and that's when you need to take advantage of these FDA-approved creams and gels. Sarecycline Sarecycline is also known as Seysara and it's a product derived from tetracycline. It can be used to effectively treat acne in people aged 11-30 years. Sarecycline is available in tablet form with dosages of 60mg, 100mg or 150mg. The dosages are given depending on the weight of the patient. For example, if the patient weighs less than 54kg (119lbs) then the recommended dosage is 60mg. If the patient weighs between 85kg (187lbs) and 136kg (299lbs) then the recommended dosage is 150mg. Patients weighing more than 54kg but less than 85kg should take the 100mg tablet. Sarecycline is used to treat moderate to severe acne in patients of all ages. Its efficiency was based on studies performed on more than 2,000 patients. The research involved a double-blind, placebo-controlled trial over a period of 12 weeks. Most of the patients experienced improvements after just 3 weeks of treatment and their acne and other skin lesions were significantly healed. The recommended dosage is to take one tablet per day with or without food. The FDA approves the use of this product, but its safety hasn't yet been established after a period of 12 months, so more research trials need to be conducted in the future. Still, sarecycline is an ideal acne product if you want to get rid of acne caused by TRT. Altreno Another great acne product you can try is Altreno, also known as tretinoin 0.05%. This topical treatment can be used on patients who are 9 years of age or older. It consists of a lotion that is applied directly to the damaged skin. The active ingredient is absorbed very quickly by the skin and it can significantly reduce moderate to severe acne in patients. The FDA approved this treatment option based on studies performed on identical research centers. These were double-blind, vehicle-controlled studies involving more than 1,600 patients. These patients were treated with Altreno for a period of 12 weeks and more than 90% of them were satisfied with the results. The lotion managed to significantly reduce inflammatory lesions and prevent the spreading of the acne to other body parts. As side effects, these were rare and involved skin exfoliation, mild pain, skin dryness, and dizziness. However, approximately 1% of the patients reported these side effects, so Altreno can be considered a pretty safe acne product to use. On top of being efficient in fighting acne, this retinoid can also moisturize the skin and prevent other types of infections or skin scarring. Patients should apply a small dose of Altreno on the affected skin and experience the first positive results in just a few weeks. Onextron Onextron has been approved by the FDA in 2014 to be an efficient and safe treatment for acne. It's also known as clindamycin phosphate and benzoyl peroxide and it can be applied as a gel on the affected skin. This treatment is suitable for patients aged 12 or older and the gel should be applied once a day for best results. This revolutionary cream has been approved by the FDA as a result of multiple studies involving almost 500 patients. These were vehicle-controlled studies performed by experienced researchers. The results of the study were impressive as more than 50% of the patients experienced significant improvements in their skin lesions. The studies lasted for 12 weeks and most of the patients were happy with the results they got after using Onextron. Approximately 1% of these patients experienced side effects such as burning sensations, allergic reactions or rashes. Such side effects were minor and they went away after a couple of days. That's why Onextron can be successfully and safely used as an acne treatment by people over 12 years of age. Differin Gel Differing Gel 0.1% is also known as adapalene and it has been approved to be used as an acne treatment since 1996. This lotion contains powerful active ingredients which are quickly absorbed by the skin. Differin Gel can be applied on the neck, shoulders, face or other body parts which contain skin lesions and imperfections. It is safe to be used by people over 12 years of age, according to the FDA. This over-the-counter medicine has been approved as a result of multiple clinical studies and trials done on hundreds of people with severe acne. Most of the patients experienced marked improvements in their skin condition. Side effects were minor and only encountered by a fraction of the people who tested this lotion. Some of these side effects include rashes, minor burning sensations, and mild allergic reactions. With that being said, Differin Gel shouldn't be applied to damaged skin which suffered cuts or scratches. This OTC medicine can be applied daily and its efficiency lasts for at least 12 months. Aczone Gel This is another useful acne cream that can be used by people over 12 years of age. Aczone Gel 7.5% is a safe and efficient lotion that can be applied daily on the affected skin. It can be used to treat minor and severe acne as well as other skin lesions from face, neck, shoulders, and chest. The FDA approved this medicine as a result of numerous multi-center, double-blind studies. More than 4,300 patients participated in these studies and almost all of them had severe acne. Aczone Gel was applied daily for a period of 12 weeks and more than half of the patients involved reported a successful outcome. The gel was effective in treating skin lesions and reducing the spreading of acne. When it comes to side effects, these are minor and only experienced by a few patients. For example, some side effects include itching or dryness of the skin. However, patients must be careful not to combine other medications they might use such as benzoyl peroxide with Aczone Gel. These 2 products can provoke serious side effects including the yellowing of the skin and the reduction of blood flow in the lips and other body parts. Aczone Gel should be used as a standalone medication and not in conjunction with other drugs. Trifarotine Cream The US Food and Drug Administration (FDA) approved trifarotene cream 0.005% (Aklief, Galderma) on October 2019, the first new retinoid molecule to be approved in the United States in over 20 years for the once-daily topical treatment of acne vulgaris. Trifarotene is the only topical retinoid that selectively targets retinoic acid receptor (RAR) gamma, the most common RAR found in the skin. It's also the first topical treatment specifically studied and proven to treat both facial (forehead, cheeks, nose, and chin) and truncal (chest, shoulders, and back) acne. It is approved for patients aged 9 years or older. Picking the Best Acne Treatment As you can see, there are a lot of great acne treatments and products you can try to get rid of your skin imperfections. Some of them are available by prescription while others are over-the-counter medicine which can be taken as pills or applied as lotions. As a rule of thumb, make sure that you always speak with your doctor or healthcare provider before beginning treatment with any of these acne products. It's ideal to be monitored by a healthcare professional who can provide recommendations when it comes to dosages or potential side effects. if you're currently on testosterone replacement therapy (TRT) and experience minor or severe acne, these products might be helpful for you. Talk with your TRT doctor and ask him which one is more appropriate for you. More information on TRT related acne.   References Testosterone and Acne: What You Need to Know The Role of Zinc in the Treatment of Acne: A Review of the Literature

Table of Contents Sleep Apnea and Testosterone Sleep Apnea and Cortisol Health Consequences of Sleep Apnea Sleep Apnea Solutions REFERENCES: Do you snore? Do you feel fatigued every day? Do you wake up frequently throughout the night? It may be that the shallow breathing or breaks in breathing caused by sleep apnea are the reason. There are different types of sleep apnea, one of which is obstructed sleep apnea (or OSA), which is when breathing is interrupted by a physical block to airflow. With OSA, snoring is common. Sleep Apnea and Testosterone What does apnea have to do with testosterone?  Everything!  Your precious shuteye is responsible for a host of all-important physiological functions, including rebuilding your testosterone and neurotransmitters, optimizing stress hormones, and mapping memory. Therefore, any condition, such as apnea that lowers the quality or quantity of sleep, is a physical and hormonal train wreck waiting to happen. Apnea is one of the nastiest sleep disorders because it is so disruptive.  After all, what could interfere with sleep more than having your airways and oxygen blocked off? Unfortunately, one study after another has rolled out showing how complex apnea is on the body, and hormones are no exception. One early study looked at just how severe the damage can be and found that apnea sufferers went from an average low testosterone test of 391ng/dL to a much closer-to-normal 487ng/dL after corrective surgery. [1] That's a jump of 25% in testosterone after their apnea was corrected!  However, a later study of guys in their 40's, showed an astonishing 68% difference between controls and males with apnea. [2] Regardless of the exact number, you get the idea:  apnea is devastating to your most precious hormone, testosterone. However, there is actually a logical explanation for the difference in the two numbers above:  the first number comes from a comparison after apnea correction and the second before correction.  Researchers have found that guys who have had apnea for a significant amount of time are often overweight, even obese. [3]    In other words, if you've built up a big spare tire during your sufferings with apnea, CPAP or other therapy cannot get you back to where you were before because your own body is fighting against itself. The researchers found that apnea subjects appeared more like aged subjects where LH (Luteinizing Hormone) cycles at night were increased, yet without a corresponding increase in testosterone as is experienced by younger males.  Young guys get a pulse of luteinizing hormone followed by one of testosterone and so on.  This cycle is dampened increasingly in males as they age, and apnea appears to accelerate this process. In other words, once you get your apnea corrected, you must take care to also lose any excess weight in order to re-optimize your testosterone as much as possible.  The good news is that just getting treated for apnea will give you a nice jump in testosterone, and then as you lose weight and control cortisol, you should increase it even further.  Studies have even verified this in obese men with a BMI of 32, which isn't what would even called obese, by the way.  When they lost weight, they regained their testosterone. [4] Sleep Apnea and Cortisol Similarly, apnea also leads to elevated cortisol level.  One study found that subjects had 50% percent higher cortisol before CPAP when compared to after. [6] This is truly nasty:  cortisol is not something you want to be elevated by even the smallest amount.  Higher cortisol elevations, especially in the middle age and beyond years, can lead to memory damage, lowered testosterone, increased fat mass, lower immunity, poor sleep and a host of other ills.   In the last ten years, researchers have uncovered the fact that most apnea is actually lifestyle-related and not simple genetics or aging. Health Consequences of Sleep Apnea Sleep apnea has been shown to increase the incidence of these health problems: Heart Disease. Blood Glucose Control and Diabetes. If you have diabetes, sleep apnea can make it more difficult to manage your diabetes. Increased blood viscosity due to high hematocrit: As you starve your body of oxygen at night with sleep apnea, the body compensates by producing more oxygen-carrying hemoglobin and red blood cells, which increases hematocrit and blood viscosity. This can cause heart disease, high blood pressure and require frequent blood donations if you are on testosterone replacement therapy (TRT). Note: TRT can worsen sleep apnea in some men [10] Memory Loss and Dementia Risks.  Heavy snoring and sleep apnoea may be linked to memory and thinking decline at an earlier age, according to a study published in the April 15, 2015, online issue of the journal Neurology. The research also suggests that treating the disorders with a breathing machine may delay the decline. “Abnormal breathing patterns during sleep such as heavy snoring and sleep apnea are common in the elderly, affecting about 52% of men and 26% of women,” said Ricardo Osorio, MD, at the NYU Langone Medical Center. Fatigue and daytime sleepiness. Depression. Irritability.   Sleep Apnea Solutions One interesting aspect of apnea research is that researchers are finding that there are many natural solutions that can often help apnea sufferers and sometimes even cure their apnea.  This is important for several reasons.  First of all, in some cases, it shows that there is a root cause of apnea, i.e., there is not some inherent genetic weakness causing this debilitating condition but rather some lifestyle change that can help significantly.  Secondly, the medical solutions for apnea are rather invasive:  surgery (somnoplasty and snoreplasties) and/or a cumbersome CPAP machine worn through the night.  Many of those with apnea would like to avoid such solutions and find something more natural. However, it should be noted that there is one other medical procedure, the Pillar procedure, that is significantly less invasive. This is performed by a dentist and involves tiny polyester implants in the soft palate of an apnea (or snoring) sufferer.  It is actually the vibration of the soft palate that can lead to snoring and often apnea, so this can be an easy fix in some cases since it is done with minimal anesthetics. WARNING:  It is critical to get your apnea treated.  One study looked at 380 participants with moderate or severe sleep apnea over a 14-year period and found that one-third of the patients died! [9] That's in comparison to 8 percent without apnea.  Those suffering from apnea or other sleep disorders should definitely consider green tea, as they get their condition under control. The oxidative stress from apnea typically affects memory and the ability to learn. Researchers have found that green tea, at least in animals, protects the brain from oxygen-deprived states that occur in apnea and related disorders. Green tea for the rats in this study actually protected their brains and memory from the ravages of apnea sleep loss. [4] Below is a summary of additional natural solutions that researchers have found for apnea:   Weight Loss. Research shows that mild apnea can often be significantly helped or even cured simply by losing those extra pounds.  One recent study found that almost two-thirds of study participants who dropped 23 pounds through diet and exercise were actually completely cured of their apnea. [2] Therefore, assuming your apnea isn't too severe, you may want to try simple weight loss first as a solution and, as a side benefit, you may have your testosterone significantly restored as well. In other words, dropping those pounds has the potential to boost your testosterone and cure your apnea at the same time.   If your apnea is severe, however, simple weight loss will not do the trick, and you will likely end up with a CPAP (Continuous Positive Airway Pressure) These masks can be testosterone and life and saver, literally.  There are also dental mouthpieces and surgery of the throat as options as well, but these are considered less effective in most cases. Your doctor can order a sleep study for you to get tested at a sleep lab or using a home-based system. There are also telemedicine services for sleep apnea. A study done in Portugal and published in 2017 found that after people used CPAP machines for six months, their red blood cell count, hemoglobin, hematocrit, and platelet count showed a significant decrease [11]   Treat Hypothyroidism. Apnea can result from hypothyroidism, an underactive thyroid that will be unresponsive to standard treatments.  It is estimated that 2-3% of apnea sufferers fall into this category. [3]   Improve Sleep Position. Some practitioners have noticed that sleeping on the side can significantly help with apnea. Another solution is to sleep in a partial sitting position.  One study showed that half of all apnea sufferers could actually cure their condition by sleeping in this position! [5]   Avoid Alcohol at Night. If I got woken up a couple of hundred times during the night from lack of oxygen, I might want a few drinks, but researchers have found that this decidedly exacerbates apnea. [6]    Stop Smoking. Smoking makes apnea significantly worse because it inflames airway tissues and is associated with an increased incidence of this condition. [7]   Avoid Sitting for Long Periods. Sitting a lot during the day pools water and blood in the legs, and this aggregation of liquids then migrates to your neck region when you go to Sleep leading to apnea in many cases.  Keep moving throughout the day. [8] Download a step counter App to your phone, carry your phone in your pocket, and measure the total steps you take daily. If you’re sedentary, add 2,000 more daily steps so that you average at least 4,400 daily steps. While 2,000 steps equals one mile, it’s not necessary to walk it all at once. Instead, try to take extra steps over the course of each waking hour.   Monitor Your Oxygen Saturation. Use an oximeter connected to a Bluetooth enabled App to see how many times your blood oxygen level drops during your sleep cycle. Bluetooth Oximeter syncs the measurement readings to the free ViHealth app via Bluetooth automatically and securely. The app can store unlimited history data, which gives you a quick overview and helps you monitor your health.   As you can see, reversing sleep apnea can not only extend your life span but also its quality.  Giving your body the oxygen it needs will change your life!   REFERENCES:   1) Journal of Sexual Medicine, 6(11):3147-3157, Published Online: 29 Jun 2009, "Sleep Apnea is an Independent Correlate of Erectile and Sexual Dysfunction" 2) Consumer Reports on Health, Jul 2009, p. 10. 3) Am. J. Respir. Crit. Care Med., Aug 1999, 160(2):732-735, "Screening for Hypothyroidism in Sleep Apnea" 4) Amer J of Respiratory and Critical Care Med, May 15 2008, Goza 5) Am Rev Respir Dis, 1986 Apr, 133(4):662-6, "The effects of posture on obstructive sleep apnea" 6) Amer J of Medicine, Aug 1981, 71(2):240-245, "Alcohol increases sleep apnea and oxygen desaturation in asymptomatic men" 7) SLEEP AND BREATHING, 5(4):167-172, "Higher Prevalence of Smoking in Patients Diagnosed as Having Obstructive Sleep Apnea" 8) Men's Health, May 2009, p. 33. 9) Sleep, 2008 Aug , ;31(8):1079-85, "Sleep apnea as an independent risk factor for all-cause mortality: the Busselton Health Study" 10) The Journal of Clinical Endocrinology & Metabolism, Volume 88, Issue 8, 1 August 2003, Pages 3605–3613. “The Short-Term Effects of High-Dose Testosterone on Sleep, Breathing, and Function in Older Men” 11)  Revista Portuguesa de Pneumologia (English Edition) Volume 23, Issue 2, March–April 2017, Pages 71-78. "Hematological evaluation in males with obstructive sleep apnea before and after positive airway pressure"  

Table of Contents Timing for Female Hormone Testing Female Hormone Testing Through Menstrual Cycle Women's Hormone Blood Testing Mistakes The Best Time for Female Hormone Blood Testing Female Hormone Testing Data Reference Timing for Female Hormone Testing   Throughout our life, male or female, many of us reach a point where things may not feel quite right. Our energy levels may be low; our desire for sexual activity is not what it used to be if it exists at all. We may be experiencing unexplained weight gain or muscle loss, not to mention issues with fertility. It is for these reasons; many men and women will seek out treatment options. Such options sought out by both sexes have increasingly been hormone treatment plans, which almost always begin with blood testing. This process is relatively more straightforward for most men, but female hormone testing is slightly more complicated. Timing for the female hormone blood panels is an essential factor that must be taken into consideration.   Female Hormone Testing Through Menstrual Cycle   When determining hormone levels within the body, a premenopausal woman requires blood tests that are timed for the most accurate results. You will find some labs, and physicians will offer saliva-based tests, which may not provide accurate results, but blood testing will often be the way to go for a fuller measure of various markers in the body.   While the various tests are essential, blood testing itself must be coupled with appropriate timing. For example, for the adult male, generally, the best time to have blood drawn for testing is the first thing in the morning on an empty stomach. Some women may follow a similar approach, but for the female, this is far from optimal. Hormone testing for premenopausal women, our focus here today, is best timed around the woman’s cycle. Fasting may be necessary as it is with men, but the female hormone blood test's timing needs further consideration.   Women's Hormone Blood Testing Mistakes   Failure to time a blood test around a woman’s cycle may render inaccurate hormone lab test results.  One may find their hormone levels similar to a postmenopausal female even if still well within the premenopausal stage of life if the timing is off. For a healthy adult female with regular menstrual cycles, estrogen and progesterone blood test levels will be extremely low at the beginning of the follicular phase of one’s cycle. These hormones will often mimic that of a menopausal female despite functioning ovaries. Any testing done during this period of a woman’s cycle is useless. Although both men and women experience fluctuations in hormone levels throughout the day, week, and even months, more significant changes usually exist within a woman’s monthly cycle.     The Best Time for Female Hormone Blood Testing   As menstrual cycle timing is crucial related to female hormone blood testing, most premenopausal women will find labs to be at their most accurate state at days 19-21 of their monthly cycle. This period is when they are at their peak production of progesterone. As alluded to before, progesterone will be lower during other points of the cycle to even seemingly nonexistent during the follicular stage.     As many women supplement with progesterone, often for fertility purposes, one might ask how this would impact their choice in timing? If a woman is supplementing with medical progesterone, as it is usually only taken during the luteal phase of her cycle, which is when progesterone is sometimes only taken for fertility purposes; it is important to have blood work done at this point to view accurate results. As is with the woman who is not taking progesterone, we are merely attempting to test our hormone levels when progesterone is at its peak.   It is important to note that some doctors prescribe testosterone for hormonal imbalances in women.  However, suppose a low dose of progesterone does not accompany this exogenous testosterone. In that case, the testosterone treatment may negate the benefits of HRT since a therapeutic-created form of estrogen dominance will affect the quality of life. The introduction of a low dose of progesterone will help normalize the whole hormone gambit within the woman’s body, thereby producing measurable results that can help her reach optimal health should treatments need adjustment.   If you still have a menstrual cycle, the time of the month for estradiol and progesterone test is essential. Wrong timing will often render your lab result useless because, at certain times of the month, healthy women with normal and suboptimal hormone profile will have similar numbers to menopausal/peri-menopausal women.  During the early follicular phase, estrogen and progesterone are naturally very low and in the menopausal range, even if you are a healthy 28-year-old with fully functioning ovaries and fertility. So, testing on the wrong days does not give you any useful data on your ovarian function. For women with 28-day cycles that ovulate on day 14, the best day to evaluate progesterone blood test levels is at its highest, seven days after ovulation.   Female Hormone Testing Data   A study published in 2006 reviewed the issue of timing of premenopausal hormone blood testing.  It was a three-year study that included regular blood testing of 113 premenopausal women. The study performed estrogen and progesterone blood tests in both the luteal phase and the women’s cycles' follicular phase.   Data from the study showed that the differences between tests performed at the luteal and follicular phases were significant. Levels of free estradiol were the only marker of relative statistical insignificance. Estrogens and androgens, among other items, were statistically opposed between the two periods of testing, reinforcing the need for women to plan their hormone blood testing accordingly with their monthly cycle. While many women do not track their cycle, if blood testing is necessary and you are attempting to get to the bottom of an issue, tracking it is essential to make sense of female hormones' lab test results.   If you find hormone testing is something you would like to do, a great place to start is with Discounted Labs’ Women’s Hormone Tests     References   Stacey A. Missmer, Donna Spiegelman, Elizabeth R. Bertone-Johnson, Robert L. Barbieri, Michael N. Pollak and Susan E. Hankinson. “Reproducibility of Plasma Steroid Hormones, Prolactin, and Insulin-like Growth Factor Levels among Premenopausal Women over a 2- to 3-Year Period.” Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):972-8. Prior JC (2020). "Women's reproductive system as balanced estradiol and progesterone actions—A revolutionary, paradigm-shifting concept in women's health". Drug Discovery Today: Disease Models. 32, Part B: 31–40.     

Are you experiencing unexplained mood swings, weight gain, or fatigue? It could be a result of a hormonal imbalance. Hormones play a crucial role in regulating various bodily functions, and when they are out of sync, it can have a significant impact on your overall well-being. In this comprehensive guide, we will delve into the world of hormonal imbalance, exploring its causes and symptoms. We will discuss the different types of hormone tests available and how to interpret the results. Additionally, we will explore both medical and natural treatment options for restoring balance to your hormones. Whether you're looking to understand your own hormone levels or seek preventive measures, this guide will provide you with the knowledge you need to take control of your health. Understanding Hormonal Imbalance Hormones play a crucial role in the body, acting as chemical messengers that regulate various bodily functions. When hormones become imbalanced, it can lead to a range of symptoms such as hot flashes, weight gain, acne, and mood swings. Hormone testing is important for diagnosing imbalances, including those related to perimenopause, and can be done through blood tests that measure hormone levels. Treatment options for hormonal imbalances include hormone replacement therapy, lifestyle changes, and supplements. By making lifestyle changes like improving sleep quality, managing stress, and maintaining a healthy weight, it's possible to naturally balance hormones and reduce inflammation, improving overall health. The keyword "inflammation" has been added exactly once to the modified paragraph. The Role of Hormones in the Body Hormones are essential chemical messengers that regulate various bodily functions and processes related to health care. They play a crucial role in growth and development, metabolism, reproduction, and mood regulation. Imbalances in hormone levels can lead to a wide range of symptoms and health issues. These imbalances can occur due to factors such as stress, diet, lifestyle choices, medications, and underlying medical conditions. To maintain overall health and well-being, it is important to identify and address hormone imbalances. By understanding the role of hormones in the body, we can take steps towards achieving hormonal balance and optimal health. What does Hormonal Imbalance Mean? Hormonal imbalance refers to an abnormality in the levels or functioning of hormones in the body. It can affect various aspects of health, including mood, energy levels, metabolism, and reproductive functions. Symptoms may include fatigue, weight changes, mood swings, irregular periods, acne, and obesity. Factors like stress, diet, medications, and underlying health conditions can contribute to hormonal imbalances. Identifying the Symptoms of Hormonal Imbalance Identifying the Symptoms of Hormonal Imbalance: Recognizing the common signs of hormonal imbalance is crucial for early detection and effective treatment. Symptoms can manifest differently in individuals, but most commonly include fatigue, mood swings, weight gain, and night sweats. Getting a hormone imbalance test is essential to accurately diagnosing and addressing hormonal imbalances. These tests, such as blood tests and saliva tests, analyze hormone levels and provide valuable insights into hormonal health. Early detection and treatment can greatly benefit overall health and well-being. Managing hormonal imbalances may involve lifestyle changes, hormone therapy, or other treatments. Common Symptoms in Women Irregular or heavy menstrual periods can indicate hormonal imbalance in women. Mood swings and irritability are common symptoms of hormonal imbalance. Fatigue and low energy levels can be signs of hormonal imbalance in females. Changes in libido or sexual desire may result from hormonal imbalances. Hair loss or thinning, as well as acne breakouts, can also be signs of hormonal imbalance, including menstruation. Changes in hormone levels, such as those of estrogen and progesterone, may be the cause of these symptoms. If you're experiencing any of these symptoms, it's important to consult with a healthcare provider to determine if hormone imbalance is the underlying cause. Common Symptoms in Men Common symptoms of hormonal imbalance in men include fatigue and low energy levels. Mood swings and irritability are often experienced by men with hormonal imbalances. Changes in libido and sexual function, such as those related to sex hormone levels, can also indicate a hormonal imbalance in males. Increased body fat, especially around the abdomen, may be a symptom of hormonal imbalance in males. Hair loss and decreased muscle mass can be signs of androgen hormonal imbalance in males. Hormones Commonly Tested for Imbalances Imbalances in hormones can have various effects on the body. Estrogen imbalances can lead to menstrual irregularities, mood swings, and weight gain. Testosterone imbalances may cause fatigue, low libido, and muscle loss. Imbalances in thyroid hormones can result in weight changes, fatigue, and mood disturbances. Cortisol imbalances can lead to chronic stress, sleep disturbances, and weight gain. Insulin imbalances can contribute to blood sugar regulation issues and weight gain. Progesterone imbalances can cause PMS symptoms, irregular periods, and fertility problems. These hormones are commonly tested for imbalances to identify and address any underlying issues. Thyroid Hormones Explained Thyroid hormones, such as TSH, T3 and T4, play a crucial role in regulating metabolism and energy levels in the body. When these hormones are imbalanced, it can lead to symptoms like fatigue, weight changes, and mood swings. Testing for thyroid hormone imbalances typically involves measuring TSH levels in the blood. Treatment options may include medication or lifestyle changes. It's important to consult with a healthcare professional for an accurate diagnosis and appropriate treatment of thyroid hormone imbalances. The Importance of Testosterone Testosterone, a vital hormone in male development, muscle growth, and libido, plays a crucial role in overall health. Low testosterone levels can lead to fatigue, mood swings, and decreased sex drive, while high levels in females may cause acne, excessive hair growth, and irregular periods. Testing testosterone levels is essential for identifying hormonal imbalances and guiding appropriate treatment. Balancing testosterone levels through lifestyle changes or hormone replacement therapy is necessary for maintaining overall well-being and optimizing health. Prioritizing the health of this important hormone can have a significant impact on one's vitality and quality of life. BUY A TESTOSTERONE TEST. Understanding Estradiol Levels Estradiol, a form of estrogen, is vital for reproductive health and bone density. Testing estradiol levels aids in diagnosing conditions like PCOS, menopause, and fertility issues. Low levels may indicate ovarian dysfunction or premature ovarian failure, while high levels may suggest hormone-producing tumors or certain medications. Monitoring estradiol levels guides hormone replacement therapy and fertility treatments. Men on testosterone therapy may experience elevated estradiol levels. Understanding and monitoring estradiol levels is essential for maintaining hormonal balance and overall health. Senstive versus Regular Estradiol Testing: LC/MS vs Immunoassays When it comes to testing estradiol levels, there are two main methods: LC/MS and immunoassays. LC/MS testing is known for its accuracy and reliability in measuring estradiol levels. It offers better sensitivity and specificity, making it a preferred choice for detecting estradiol imbalances. On the other hand, immunoassays are less expensive and more widely available but may produce less accurate results due to potential cross-reactivity with other hormones. The choice between the two tests depends on factors such as cost, availability, and desired level of precision. BUY A SENSITIVE ESTRADIOL TEST. The Role of Prolactin in the Body The pituitary gland's hormone, prolactin, is essential for both breastfeeding and milk production. Imbalances in prolactin levels can lead to various reproductive issues, including breast tenderness. High prolactin levels may cause irregular periods, erectile dysfunction, low testosterone, infertility, and breast milk production in non-pregnant individuals. On the other hand, low prolactin levels can result in difficulty breastfeeding and a low milk supply. Testing prolactin levels is necessary to diagnose conditions such as hyperprolactinemia or hypoprolactinemia, which can affect reproductive health and overall hormonal balance. A proper balance of prolactin is imperative for the optimal functioning of the body. BUY A PROLACTIN TEST. Why Cortisol Levels Matter Cortisol levels are vital to our overall hormonal health and well-being. As a stress hormone, cortisol plays a significant role in regulating our body's response to stress. When cortisol levels become imbalanced, it can lead to symptoms such as fatigue, weight gain, and mood swings. Testing cortisol levels is crucial for identifying adrenal gland dysfunction and hormone imbalances. By monitoring cortisol levels, we can better manage stress levels and optimize our overall health. There are different methods for testing cortisol levels, including salivary cortisol and cortisol blood test, which can provide valuable insights into our hormonal balance. IGF-1 and its Significance IGF-1, which the liver produces, is essential for growth and development. Testing IGF-1 levels aids in detecting growth disorders and assessing treatment effectiveness. Anomalies in IGF-1 levels can indicate conditions like acromegaly or growth hormone deficiency. Maintaining optimal IGF-1 levels is crucial for overall well-being. Regular monitoring of IGF-1 enables the identification and management of hormone imbalances. It is important to understand the significance of IGF-1 and its role in maintaining hormonal balance. BUY AN IGF-1 TEST. Other Notable Hormones In addition to the commonly tested hormones, there are other notable hormones that may be assessed for imbalances. These include DHEA, pregnenolone, and progesterone. Testing these hormones can provide valuable insights into overall hormonal health and balance. Imbalances in these hormones can contribute to various symptoms and health conditions. It is important to work with a healthcare professional to determine which hormones should be tested based on individual circumstances. The Process of Hormone Imbalance Testing The process of hormone imbalance testing involves understanding the symptoms of hormone imbalance and the importance of testing. There are different types of hormone imbalance tests available, including blood tests, saliva tests, and urine tests. To prepare for hormone imbalance testing, follow fasting requirements and medication restrictions. The process of collecting samples for testing varies depending on the type of test, and it usually takes a few days to receive the results. Interpreting hormone imbalance test results is essential to understanding the potential treatment options available. When Should You Consider a Hormone Imbalance Test? If you're experiencing symptoms like fatigue, weight changes, mood swings, irregular periods, or low libido, it may be time to consider a hormone imbalance test. Additionally, a family history of hormonal disorders or fertility issues can also warrant testing. Consulting with a healthcare professional can help determine if a hormone imbalance test is right for you. How Do Hormone Imbalance Tests Work? Hormone imbalance tests work by analyzing blood or saliva samples in a laboratory to measure hormone levels. These tests help identify any imbalances or abnormalities, aiding in the diagnosis and treatment of various conditions. The Steps Involved in Sample Collection Sample collection for hormone imbalance testing typically involves collecting samples of blood, urine, or saliva. These samples can be collected at a doctor's office, laboratory, or in the comfort of your own home. The specific collection method may vary depending on the hormones being tested. It is crucial to follow the instructions provided by the healthcare professional or testing kit manufacturer to ensure proper sample collection and handling, which in turn, ensures accurate test results. Proper sample collection is essential for obtaining reliable information about hormone levels. Interpreting the Results of Hormone Imbalance Test Interpreting the results of hormone tests requires the expertise of a healthcare professional who is familiar with your medical history. The interpretation depends on the specific hormones being tested and their reference ranges. Abnormal hormone levels may indicate hormonal imbalances, which should be further investigated and potentially treated. It's important to note that hormone levels can fluctuate throughout the day and vary based on factors like age and menstrual cycle phase. Regular monitoring of hormone levels can help track progress and guide treatment plans for hormone imbalances. Different Types of Hormone Imbalance Test There are various types of hormone imbalance tests used to assess hormonal health and identify imbalances. Blood tests measure hormone levels in the blood, providing a comprehensive overview of the body's hormone profile. Saliva tests focus on cortisol and testosterone levels and involve collecting saliva samples. Urine tests assess hormone balance by measuring hormone metabolites in the urine. Hair tests analyze long-term hormone levels and imbalances. Functional medicine tests take a holistic approach, assessing overall hormonal health and identifying underlying causes of imbalances through comprehensive testing. Comprehensive Hormone Testing for Females Comprehensive hormone testing for females involves a thorough analysis of hormone levels. These tests are essential in identifying hormonal imbalances that may be responsible for symptoms or health issues. By measuring multiple hormones such as estrogen, progesterone, and testosterone, comprehensive testing provides valuable insights into an individual's hormone profile. The results obtained from these tests can then guide personalized treatment plans to address any imbalances. To determine the appropriate hormone testing for individual needs, it is important to consult with a healthcare professional who specializes in endocrinology. Basic Hormone Testing for Men Basic hormone testing for men can help identify imbalances in testosterone, estrogen, and other key hormones. This type of testing typically involves a blood or saliva sample to measure hormone levels. It can provide valuable insights into reproductive health, mood, energy levels, and more. Results from basic hormone testing can guide treatment options and help restore hormonal balance. If males are experiencing symptoms of hormone imbalance, such as low libido or fatigue, it is recommended to consider basic hormone testing. General Hormone Testing Options There are several general hormone testing options available to assess hormone levels in the body. Blood tests are a common method used to measure hormone levels and provide valuable insights into overall hormonal balance. Saliva tests, on the other hand, can provide a more accurate picture of hormone levels throughout the day, capturing any fluctuations that may occur. Urine tests help assess hormone metabolites and provide a comprehensive view of hormone balance. Additionally, hair tests can detect long-term hormone imbalances and potential nutrient deficiencies. Finally, functional testing offers a comprehensive approach to evaluating specific hormone imbalances and uncovering their root causes. Tests Specific to Menopause Menopause tests can help identify and diagnose hormonal imbalances during this transitional phase. Common tests include measuring levels of estrogen, progesterone, and follicle-stimulating hormone (FSH). Saliva, blood, and urine tests are widely used to assess hormone levels in menopausal women. These tests can provide valuable insights into the hormonal changes that contribute to menopause symptoms such as hot flashes and mood swings. It is important to consult with a healthcare professional to determine the most appropriate hormone imbalance test for menopause. Thyroid Hormone Testing Thyroid hormone testing plays a crucial role in identifying abnormalities in thyroid hormone levels. Commonly used tests such as TSH, T3, and T4 measurements help assess thyroid function and diagnose conditions like hypothyroidism or hyperthyroidism. The results from these tests guide appropriate treatment options, and regular monitoring of thyroid hormone levels is essential for managing thyroid disorders. By monitoring thyroid hormone levels, healthcare providers can maintain optimal thyroid function and ensure overall health. Comparing Different Hormone Imbalance Tests Blood tests are the most common type of hormone imbalance test, measuring hormone levels in the blood. Saliva tests offer a potentially more accurate representation of cortisol hormone levels, while urine tests provide information on how the body is processing hormones by measuring hormone metabolites. Hair tests offer a long-term perspective on hormone imbalances, and skin patch tests absorb hormones to reflect imbalances. Diagnostic imaging is used in specific cases to visualize hormone-producing organs like the thyroid or ovaries. Understanding the Causes of Hormonal Imbalances Hormonal imbalances can arise from a variety of factors, including stress, diet, genetics, and certain medical conditions. These imbalances often manifest through symptoms such as fatigue, weight fluctuations, mood swings, and irregular menstrual cycles. When testing for hormonal imbalances, healthcare professionals may utilize blood tests to measure hormone levels. Treatment options, which vary depending on the underlying cause, can include lifestyle adjustments, medications, hormone replacement therapy, or even surgery. For an accurate diagnosis and appropriate treatment, it is essential to consult with a healthcare professional. Lifestyle Factors Affecting Hormone Levels Several lifestyle factors can contribute to hormonal imbalances. Poor diet, lack of exercise, and high levels of stress are known culprits. Exposure to environmental toxins, such as pesticides and chemicals in household products, can disrupt hormone levels. Additionally, irregular sleep patterns and inadequate sleep can negatively impact hormone production. Excessive alcohol consumption and smoking have also been linked to disruptions in hormone levels. It's important to note that certain medications, including hormonal birth control, can cause imbalances as well. Taking steps to address these lifestyle factors is crucial for achieving hormonal balance and overall health. Medical Conditions Leading to Hormone Imbalances There are numerous medical conditions that can cause hormonal imbalances. Polycystic ovary syndrome (PCOS) and hypothyroidism are two common conditions that can disrupt hormone balance. Additionally, certain medications, like corticosteroids and hormone replacement therapy, can have an impact on hormone levels. Endocrine disorders, such as diabetes and adrenal gland disorders, can also lead to hormonal imbalances. Chronic stress and poor sleep are contributing factors as well. It is crucial to consult with a healthcare professional to identify and address the underlying medical conditions causing hormonal imbalances. How is Hormonal Imbalance Treated? Treatment for hormonal imbalance varies based on the specific condition and underlying cause. It may involve medication, lifestyle changes, or hormone replacement therapy. Consulting with a healthcare professional is crucial to determining the most suitable treatment plan for your specific hormonal imbalance. Medical Treatments for Hormonal Imbalance Hormonal imbalance can be addressed through various medical treatments tailored to the individual's symptoms, hormone levels, and overall health. Hormone replacement therapy (HRT) is a common approach to restoring hormonal levels and alleviating symptoms. Additionally, prescription medications can be used to regulate specific hormones and address specific symptoms. Lifestyle changes, such as adopting a balanced diet and engaging in regular exercise, can also help naturally balance hormones. Alternative therapies like acupuncture and herbal supplements may provide additional support in treating hormonal imbalances. The treatment plan for hormonal imbalance is personalized and takes into account the unique needs of each individual. Natural Remedies for Hormone Imbalances Natural remedies, such as dietary changes and herbal supplements, can be effective in restoring hormone balance. Incorporating a nutritious diet rich in fruits, vegetables, and whole grains can support hormone levels. Additionally, certain herbal supplements like maca root or black cohosh may help alleviate symptoms of hormonal imbalance. Regular exercise not only promotes overall health but also aids in hormone regulation. Stress management techniques, such as meditation or yoga, can also have a positive impact on hormone balance. Essential oils like lavender and clary sage can be used topically or in a diffuser to provide hormonal support. Alternative therapies like acupuncture may offer additional benefits for hormone imbalances. However, it's essential to consult with a healthcare professional to determine the best natural remedies for your specific hormone imbalance. How Accurate Are At-Home Hormone Tests Compared to Blood Draw Hormone Tests? At-home hormone tests offer convenience and affordability, but they may have slightly less accuracy compared to blood draw tests conducted in a laboratory. Blood draw tests are considered the gold standard for hormone testing due to their higher accuracy and reliability. For highly accurate results or specific hormone monitoring, consult a healthcare professional for a blood draw test. Can Hormone Imbalances be Prevented? Preventing all hormone imbalances may not be possible, but promoting hormonal balance is within reach. Maintain a healthy lifestyle with exercise and a balanced diet. Manage stress through relaxation techniques. Regular check-ups can detect and address imbalances early on. The Role of Sleep Quality, Body Weight, and Stress on Hormone Imbalances Poor sleep quality can disrupt hormone production, leading to imbalances. Maintaining a healthy body weight regulates hormone levels and prevents imbalances. Chronic stress negatively impacts hormone function, increasing the risk of imbalances. Prioritizing good sleep hygiene, maintaining a healthy weight, and managing stress help prevent hormone imbalances. Adopting lifestyle habits that support hormone balance is crucial for overall well-being. Proper sleep, optimal body weight, and stress management contribute to the maintenance of hormonal equilibrium, promoting overall health. How to Buy Affordable Lab Tests to Determine Hormone Imbalances on DiscountedLabs.com Discovering and addressing hormone imbalances is essential for overall health and well-being. When it comes to buying affordable lab tests to determine hormone imbalances, DiscountedLabs.com is a reliable option. They offer a wide range of hormone imbalance tests that measure various hormones such as thyroid, testosterone, progesterone, and estrogen. Ordering and receiving test results from DiscountedLabs.com is convenient and straightforward. By purchasing hormone imbalance tests online, you can benefit from affordability and the convenience of at-home testing. Take control of your health and buy hormone imbalance tests at discountedlabs.com. Conclusion In conclusion, understanding and addressing hormone imbalances is crucial for maintaining overall health and well-being. Hormones play a vital role in various bodily functions, and any imbalance can lead to a range of symptoms and health concerns. If you are experiencing symptoms such as fatigue, mood swings, weight gain, or decreased libido, it may be beneficial to consider a hormone imbalance test. This will help identify any underlying issues and guide appropriate treatment options. Whether you opt for medical treatments or natural remedies, it's important to work with healthcare professionals to find the best approach for your specific needs. Take charge of your hormonal health and start prioritizing your well-being today. To get started, visit DiscountedLabs.com and explore affordable lab test options to determine hormone imbalances.  

Testosterone, a vital hormone predominantly found in males, plays a crucial role in various physiological processes such as sexual development, muscle growth, bone density, and overall well-being. Recent studies have raised concerns about a decline in serum testosterone levels among adolescents and young adult men in the United States. This article aims to explore the potential causes, implications, and scientific evidence surrounding this phenomenon. Factors Contributing to Declining Testosterone Levels in Young Men Lifestyle Changes Sedentary behavior, unhealthy dietary patterns, and an increase in screen time have been linked to lower testosterone levels. Lack of physical activity and poor nutrition can lead to weight gain, which is associated with reduced testosterone production [1]. Endocrine Disruptors Exposure to endocrine-disrupting chemicals (EDCs) such as phthalates, bisphenol A (BPA), and pesticides has been suggested as a potential contributor to declining testosterone levels. These chemicals, commonly found in plastics, personal care products, and certain foods, can interfere with hormonal balance and disrupt testosterone synthesis [2]. Stress and Mental Health Chronic stress and mental health disorders, including depression and anxiety, may negatively impact testosterone production. Elevated cortisol levels, often associated with stress, can suppress testosterone synthesis [3]. Obesity and Insulin Resistance The rising prevalence of obesity and insulin resistance among adolescents and young adults has been linked to lower testosterone levels. Excess body fat can promote the conversion of testosterone into estrogen, leading to hormonal imbalances [4]. Implications of Declining Testosterone Levels Sexual and Reproductive Health Testosterone is essential for normal sexual function, including libido, erectile function, and sperm production. Declining testosterone levels may contribute to sexual dysfunction and reduced fertility in affected individuals. Physical Health Testosterone plays a crucial role in maintaining muscle mass, bone density, and overall physical well-being. Decreased testosterone levels may lead to decreased muscle strength, increased risk of osteoporosis, and compromised overall health. Psychological Well-being Testosterone influences mood, cognition, and overall psychological well-being. Low testosterone levels have been associated with symptoms such as fatigue, depression, irritability, and reduced quality of life. Scientific Evidence and Studies A study published in the Journal of Clinical Endocrinology & Metabolism in 2006 analyzed data from the National Health and Nutrition Examination Survey (NHANES) and found a significant decline in testosterone levels among men aged 20-74 years between 1988 and 2004 [5]. Another study published in JAMA Internal Medicine in 2020 examined testosterone levels in over 4,000 young men aged 15-39 years from 2009 to 2016. The findings indicated a substantial decline in testosterone levels during this period [6]. Research published in the journal Environmental International in 2020 explored the association between phthalate exposure and testosterone levels in young men. The study suggested that higher urinary phthalate metabolite concentrations were associated with lower testosterone levels [7]. Conclusion The decline in serum testosterone levels among adolescents and young adult men in the USA is a concerning trend with potential implications for sexual and reproductive health, physical well-being, and psychological functioning. Lifestyle factors, endocrine disruptors, stress, obesity, and insulin resistance are among the factors contributing to this decline. Further research is needed to understand the extent of the issue and develop strategies to address and mitigate the potential consequences. Buy the most affordable testosterone test in the country on DiscountedLabs.com References: Araujo AB, Dixon JM, Suarez EA, et al. Clinical review: Endogenous testosterone and mortality in men: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2011;96(10):3007-3019. Haider A, Yassin A, Doros G, Saad F. Effects of long-term testosterone therapy on patients with "diabesity": results of observational studies of pooled analyses in obese hypogonadal men with type 2 diabetes. Int J Endocrinol. 2014;2014:683515. Morales A, Bebb RA, Manjoo P, et al. Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline. CMAJ. 2015;187(18):1369-1377. Almeida OP, Hankey GJ, Yeap BB, et al. Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men. Arch Gen Psychiatry. 2008;65(3):283-289. Travison TG, Araujo AB, O'Donnell AB, et al. A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab. 2007;92(1):196-202. O'Connor DB, Archer J, Wu FC. Effects of testosterone on mood, aggression, and sexual behavior in young men: a double-blind, placebo-controlled, cross-over study. J Clin Endocrinol Metab. 2004;89(6):2837-2845. Hammoud A, Gibson M, Peterson CM, et al. Impact of male obesity on infertility: a critical review of the current literature. Fertil Steril. 2008;90(4):897-904.