Page 2 - Testosterone Replacement Monitoring Tests

Testosterone replacement therapy (TRT) is a medical treatment used to address low testosterone levels in men. Before initiating TRT, doctors conduct blood tests to measure total and free testosterone levels and evaluate symptoms such as low sex drive, erectile dysfunction, fatigue, low mood, and cognitive issues. Once TRT is underway, regular monitoring through blood tests is essential to ensure optimal outcomes and minimize potential side effects. This article explores the importance of blood tests in monitoring TRT, highlighting key values to consider for maximizing benefits and preventing complications. Table of Contents Blood Tests for Initial Assessment and Treatment Selection  Methods of Testosterone Replacement Therapy Follow-Up Blood Tests and Dosage Adjustments Monitoring Testosterone Levels Importance of Free Testosterone and Sex Hormone-Binding Globulin (SHBG) Monitoring Hematocrit Levels PSA Levels and Prostate Health Balancing Estradiol Levels Monitoring Blood Pressure Kidney Function (eGFR) Assessment Monitoring Liver Enzymes Thyroid Function Assessment Checking Iron Levels Monitoring HDL Cholesterol Levels Assessing Prolactin Levels Affordable Blood Testing Services and Additional Resources Conclusion Blood Tests for Initial Assessment and Treatment Selection Before initiating TRT, doctors rely on blood tests to assess testosterone levels and evaluate symptoms. Measuring total and free testosterone levels provides crucial information about hormone deficiencies. Additionally, asking patients about their symptoms helps identify possible signs of low testosterone. Based on these findings, doctors can determine the appropriate treatment approach for each individual.  Methods of Testosterone Replacement Therapy TRT can be administered using various methods, including injections, creams, gels, pellets, and nasal gels. The choice of method depends on factors such as patient preference, convenience, and specific medical considerations. The doctor's expertise is crucial in selecting the most suitable TRT option to ensure optimal results. Follow-Up Blood Tests and Dosage Adjustments Once TRT has commenced, regular follow-up blood tests are conducted around weeks six or eight. These tests help evaluate the effectiveness of the treatment and determine if any adjustments to dosage or additional medications are necessary. For instance, estradiol modulation may be required to maintain hormonal balance. Monitoring hormone levels through blood tests enables doctors to fine-tune treatment plans and ensure that patients receive the most beneficial outcomes from TRT. Monitoring Testosterone Levels Monitoring testosterone levels is a critical aspect of TRT. The target total testosterone level for men on TRT is typically above 500 nanograms per deciliter. If the measured level falls below this threshold, adjustments to dosage or injection frequency may be necessary to achieve optimal hormone balance. Importance of Free Testosterone and Sex Hormone-Binding Globulin (SHBG) Besides total testosterone, free testosterone levels are also significant. Free testosterone represents the portion of testosterone that is readily available for biological activity. Ideally, free testosterone should be around 2% of the total testosterone or higher. Lower levels may indicate issues related to sex hormone-binding globulin (SHBG), a protein that binds to testosterone and reduces its availability for use. Monitoring free testosterone levels helps doctors identify and address any SHBG-related concerns to optimize TRT outcomes. Monitoring Hematocrit Levels Hematocrit levels, which measure the proportion of red blood cells in the blood, should be monitored during TRT. Testosterone replacement can increase red blood cell count in some individuals. Elevated hematocrit levels can lead to increased blood viscosity and potential cardiovascular issues. To mitigate these risks, the ideal hematocrit range during TRT is below 53. Regular monitoring of hematocrit levels allows doctors to identify any concerns and take appropriate measures to maintain cardiovascular health. PSA Levels and Prostate Health Prostate-specific antigen (PSA) levels play a crucial role in monitoring prostate health during TRT. Men with a PSA level of four or higher require careful evaluation, as it may indicate prostate-related concerns, including the possibility of prostate cancer. Further investigation and consultation with a urologist are usually recommended for individuals with high PSA levels. Monitoring PSA levels is vital to ensuring the safe and effective administration of TRT. Balancing Estradiol Levels Estradiol, a form of estrogen, plays a significant role in men's health and well-being. Balancing estradiol levels is essential to maximizing the benefits of TRT. Very low or high estradiol levels can have negative effects on mood, cognition, cardiovascular health, sex drive, and body composition. The optimal range for estradiol levels provided by lab companies in men typically falls between 20 and 40 picograms per milliliter. However, this range does not apply to men with high testosterone blood levels caused by TRT. Regular monitoring of estradiol levels allows doctors to ensure hormonal balance and adjust treatment if necessary. Monitoring Blood Pressure Blood pressure monitoring is essential during TRT, as some men may experience increases in blood pressure due to hormonal changes. Lifestyle modifications such as weight loss, regular exercise, and medication can help manage blood pressure levels effectively. Regular blood pressure monitoring allows doctors to identify any changes and implement appropriate interventions to maintain cardiovascular health. Kidney Function (eGFR) Assessment Assessing kidney function is an important aspect of monitoring TRT. Estimated glomerular filtration rate (eGFR) is a measure used to evaluate kidney function. Contrary to common misconceptions, TRT itself does not cause a decrease in eGFR. Regular assessments of kidney function help ensure the safety and effectiveness of TRT by identifying any potential renal complications. Monitoring Liver Enzymes Liver enzyme levels, such as aspartate transaminase (AST) and alanine transaminase (ALT), should be monitored during TRT. It is important to note that TRT has not been shown to increase liver enzymes. However, men who engage in heavy weightlifting exercises may experience artificial increases in AST and ALT levels, which are unrelated to TRT or liver toxicity. Proper interpretation of liver enzyme levels is crucial to avoid unnecessary concerns or interventions. Thyroid Function Assessment Thyroid function should be monitored during TRT to ensure overall hormonal balance. Thyroid-stimulating hormone (TSH) levels are typically measured to evaluate thyroid function. A TSH level below 2.5 is indicative of a healthy thyroid. Further tests, such as measuring free triiodothyronine (T3) and free thyroxine (T4), may be conducted to assess thyroid function more comprehensively. Monitoring thyroid function allows doctors to address any thyroid-related issues that may impact TRT outcomes. Checking Iron Levels Regular monitoring of iron levels is important, particularly for individuals who frequently donate blood. Frequent blood donations can deplete iron stores, leading to fatigue and other related symptoms. To maintain optimal iron levels, individuals undergoing TRT should ensure that donation frequency aligns with recommended guidelines. If iron levels are found to be low, supplementation may be necessary to mitigate fatigue and maintain overall well-being. Monitoring HDL Cholesterol Levels High-density lipoprotein (HDL) cholesterol levels can be affected by TRT, especially at higher doses. Higher doses of testosterone replacement therapy may lead to a decrease in HDL cholesterol, which is a concern for cardiovascular health. Regular monitoring of lipid levels, including HDL cholesterol, allows doctors to assess cardiovascular risk and consider interventions such as niacin supplementation to manage HDL levels effectively. Assessing Prolactin Levels Prolactin levels are typically checked in men with very low testosterone levels or those who do not respond well to TRT. Elevated prolactin levels may indicate underlying issues that could impact the effectiveness of TRT. While prolactin is commonly associated with lactation in women, men also produce this hormone, and imbalances can lead to complications such as erectile dysfunction. Monitoring prolactin levels helps doctors ensure optimal treatment response for individuals undergoing TRT. Affordable Blood Testing Services and Additional Resources Discountedlabs.com offers affordable blood testing services, including the necessary tests for monitoring TRT labs. The website provides various blood test options, and results are typically delivered within five to seven business days. Additionally, Excel mail.com offers further information and resources on blood tests and TRT, including a blog page and a resources including a free downloadable book titled "Beyond Testosterome." These resources can help individuals educate themselves, better understand their blood test results, and make informed decisions about their TRT journey. Conclusion Monitoring TRT through regular blood tests is crucial for maximizing the benefits and preventing potential side effects. Key values to consider during blood tests include total and free testosterone levels, hematocrit levels, PSA levels, estradiol levels, blood pressure, kidney function, liver enzymes, thyroid function, iron levels, HDL cholesterol levels, and prolactin levels. Affordable blood testing services like Discountedlabs.com and resources from Excel mail.com provide individuals undergoing TRT with accessible options for monitoring their hormone levels effectively. Regular communication with healthcare professionals is vital to tailor TRT treatment and ensure its safety and efficacy. By monitoring key values through blood tests, individuals can optimize the benefits of TRT and enhance their overall well-being.            

Key Highlights Discover the importance of testosterone testing and its impact on men's health. Explore a curated selection of reputable online labs offering competitive prices. Learn insider tips to save money, including promotional codes and leveraging insurance. Find answers to frequently asked questions about testosterone testing and its significance. Understand the value of DiscountedLabs.com for affordable and convenient testing options. Get insights into interpreting your test results and discussing them with a healthcare provider. Introduction In men's health, knowing your testosterone levels is very important. A basic testosterone blood test, also known as the T test, measures this key sex hormone. It can give you helpful information about your overall health and well-being, and plays a crucial role in diagnosing and treating hormonal imbalances like low testosterone (male hypogonadism) and monitoring hormone replacement therapy, such as testosterone therapy. As men get older, testosterone levels often go down, which can cause health problems. This blog will introduce you to the importance of testosterone testing and the men’s health test price online. It will give you the knowledge you need to make good choices about your health with the guidance of a health care provider. Top Picks for Best Testosterone Test Prices Online Finding a cheap and trustworthy testosterone test is easier than you might expect. Many online labs now offer fair prices and easy testing options. These labs let you order tests online and then go to a nearby lab to give a sample. We will look at some of the best options for testosterone test prices online. We will think about things like cost, ease of use, and expert ratings. Also, we will share tips for finding a good and reliable provider for your testosterone testing needs. Where to Find the Best Prices for Testosterone Tests When you want to find the best testosterone test price online, it's important to compare prices from different labs. This means looking at the total costs, which includes the test price, shipping fees, and any extra charges. Good online labs usually share clear pricing information on their websites, making it easy to compare. Additionally, be sure to check if the lab offers a secure online portal for accessing your test results, as this can provide convenience and peace of mind. It is also important to consider the quality of the lab and their laboratory tests, as accurate and reliable results are crucial for making informed decisions about your health. Here are the prices for the "Testosterone, Free (Equilibrium Dialysis) and Total, MS" test from different labs: DiscountedLabs.com: $45.15 minus coupon: 10percentoff = $ 40.63 Ulta Lab Tests: $ 59 WalkinLabs: $68 PrivateMDLabs: $85   Keep in mind that just choosing the lab with the lowest price may not be the best way to go. Check for labs that are certified, follow privacy rules, and have good reviews from customers. 2. DiscountedLabs.com: Unbeatable Deals and Offers on Testosterone Tests DiscountedLabs.com is a leader in offering affordable testosterone tests. The website makes it easy for you to find and compare different testosterone test options and prices. They work with certified labs, so you can trust the accuracy of your test results. What makes DiscountedLabs.com unique is its focus on keeping costs low. The site often has special deals, discounts, and package offers, making it easier for more people to get testosterone tested. If you have a healthcare provider who uses a certain lab, DiscountedLabs.com can help you with that, too, so your testing is hassle-free. By focusing on convenience and low prices, DiscountedLabs.com helps people take charge of their health and understand their testosterone levels better. 3. Specialized Testosterone Test Packages for Varied Needs Understanding testosterone testing can feel confusing. But, many online labs now offer special test packages just for you. This personalized approach makes the testing easier and helps you get the right information. For example, if you worry about low testosterone, some labs provide packages that include a total testosterone test. These packages may also have other important hormone tests, like free testosterone and sex hormone-binding globulin (SHBG). Together, they give a better look at your hormone levels, including free testosterone levels. This helps healthcare providers make smart decisions and suggest the right treatments from specialized testing centers, such as specialty testing laboratories within the national network of primary clinical laboratories that perform regular quality assurance testing. 4. Insider Tips on Finding Promotional Codes and Discounts Saving money on testosterone tests is possible. Smart shoppers can use different ways to lower the costs of keeping track of their health. Here are some helpful tips to find promo codes and discounts for testosterone tests: Sign up for Lab Newsletters: Online labs often send exclusive deals and promo codes to their email subscribers. Follow on Social Media: Discounted Labs shares discounts and special offers on Facebook. Check Health Insurance: Sometimes, your health insurance might cover part or all of the cost of testosterone testing if it is needed for medical reasons. Using these money-saving tips can make testosterone testing easier. This way, you can focus on your health without spending too much. 5. Understanding the Value of Bundle Testing Options For people who want to keep track of their testosterone levels over a long period of time, bundling testing options using panels can save them money. Online labs usually give you lower prices when you buy several tests at once. This is especially helpful if you will need regular testosterone tests, like if you are on hormone replacement therapy. Here are other testosterone-related panels available on Discounted Labs: Testosterone (T+F), Estradiol and DHT Panel Testosterone (T+F), Hematocrit, Ultra Sensitive Estradiol and Prolactin Panel Testosterone (Total + Free), Ultrasensitive Estradiol & Hematocrit Testosterone + LH + FSH Panel Testosterone, Free (Equilibrium Dialysis) and Total, MS Testosterone, Free, Bioavailable and Total (With Lower & Upper Limit) plus SHBG Testosterone, SHBG, Hematocrit, Sensitive Estradiol and PSA Testosterone, Thyroid and Estradiol Panel Testosterone, Total ( LC/MS), Free T (Equilibrium Dialysis), Bioavailable T, and SHBG Testosterone, Total and Free (NO Upper Limit) plus Hematocrit Pre- TRT MALE Hormone / Wellness Panel TRT Basic Monitoring Panel TRT MALE Hormone/Wellness Follow Up Panel Buying in bulk (also called bundling) not only lowers the cost for each test but also makes it easier because you don’t have to place separate orders each time. It is a good option for people who want to stay on top of their health. But remember to check the expiration dates of the test kits when you buy in bulk. By thinking about your needs and the savings from bulk testing, you can make smart choices about how to manage your budget for testosterone monitoring. Why Testosterone Levels Matter for Men Testosterone is mostly known as the male sex hormone. However, it does much more than just impact sexual health. It also helps with muscle growth, bone density, mood, and brain function. For men of all ages, keeping testosterone levels healthy is key to overall well-being. When testosterone levels are off balance, it can cause various changes. These changes can be physical, emotional, or mental. It's important to recognize the signs and symptoms of low testosterone. This way, you can get medical help and look into possible treatments. The Critical Role of Testosterone in Male Health Testosterone is the main male sex hormone. It helps many important functions in a man's body. Besides its known role in sex drive and sperm production, testosterone also affects muscle mass, bone density, and red blood cell production. It is important to keep healthy testosterone levels. This helps with strong bones, better muscle growth and strength, and keeps energy levels up. Testosterone, a vital sex hormone in those assigned male at birth, is also a key hormone for mood, thinking, and heart health, as well as fat distribution in the body. In men, testosterone helps regulate sex drive and erectile function, muscle mass and strength, body fat distribution, bone density, and production of red blood cells and sperm. Low levels of testosterone or “low T,” may cause a variety of health challenges and changes to your overall health and physical appearance. As men get older, their testosterone levels drop. This can lead to lower sex drive, less muscle mass, and more tiredness. Understanding how testosterone affects male health is crucial. It shows why men should check their levels and get help from experts if there are any issues. Signs and Symptoms of Low Testosterone Levels Low testosterone, known as hypogonadism, can show up in different ways. It can affect your body and mind. Common signs include a lower sex drive, problems with erections, less muscle mass, and feeling more tired. Men with low testosterone might also see changes in their body, like more body fat and weaker bones. This condition can also affect feelings and thoughts, causing mood swings, irritability, trouble focusing, and sleep issues. It's important to notice these signs as possible signs of low testosterone. If you see any of these symptoms, it's good to talk to a healthcare professional about testing and treatment options. Long-Term Health Implications of Imbalanced Testosterone Maintaining balanced hormone levels is important for your health and well-being. Testosterone is the main male sex hormone. It plays a key role in many body functions. If its levels are too low, it can lead to serious long-term health problems. Low testosterone levels can increase the risk of health issues like heart disease, osteoporosis, type 2 diabetes, and metabolic syndrome. They can also lead to mood problems, sleep issues, and problems with thinking. Managing testosterone levels is important. Regular check-ups, changes in lifestyle, and the right medical help can lower the chances of these health issues. This can also improve your overall quality of life. Differences, Advantages, and Disadvantages of Different Testosterone Tests 1. At-Home Testosterone Kits   - Collection Method: At-home testosterone kits typically involve collecting a blood or saliva sample using a finger prick or saliva swab.   - Advantages:    - Convenience: At-home testosterone kits provide the convenience of testing testosterone levels from the comfort of your own home.    - Privacy: Some individuals may prefer the privacy of conducting the test at home.   - Disadvantages:     - Limited Accuracy: At-home testosterone kits may have limitations in terms of accuracy and reliability compared to tests conducted in a clinical setting.    - Lack of Professional Interpretation: Results from at-home kits may not come with professional interpretation, requiring individuals to seek medical advice for proper understanding and guidance. 2. Saliva Testosterone Test   - Collection Method: Saliva testosterone tests involve collecting a saliva sample using a swab or collection device.   - Advantages:    - Non-Invasive: Saliva testosterone tests are non-invasive and can be easily self-administered.    - Convenient: Saliva samples can be collected at any time and do not require a blood draw.   - Disadvantages:    - Limited Availability: Saliva testosterone tests may not be as widely available as blood tests.    - Potential Variability: Saliva testosterone levels may not always accurately reflect total testosterone levels in the blood. 3. LC/MS/MS Total Testosterone Test   - Collection Method: The LC/MS/MS (Liquid Chromatography-Mass Spectrometry) total testosterone test requires a blood sample typically collected from a vein in the arm.   - Advantages:    - High Accuracy: LC/MS/MS is considered a highly accurate method for measuring total testosterone levels.    - No Upper or Lower Limit: Unlike the immunoassay testosterone test, the LC/MS testosterone test is accurate at very low or very high testosterone blood levels.   - Widely Accepted: LC/MS/MS is a commonly used method in clinical settings for testosterone testing.   - No interference by supplements like biotin.   - Disadvantages:     - Requires a Blood Draw: Some individuals may find the process of having blood drawn uncomfortable or inconvenient.    - Laboratory Processing Time: Results from LC/MS/MS tests may take longer to obtain compared to rapid tests. 4. Immunoassay-Based Testosterone Test   - Collection Method: Immunoassay-based testosterone tests also require a blood sample, typically collected from a vein in the arm.   - Advantages:    - Rapid Results: Immunoassay-based tests can provide relatively quick results.    - Cost-Effective: Immunoassay-based tests are generally more cost-effective compared to LC/MS/MS tests .  - Disadvantages:    - Potential for Interference: Immunoassay-based tests may be susceptible to interference from certain substances or conditions, potentially affecting accuracy.    - Lower Sensitivity: Immunoassay-based tests may have lower sensitivity compared to LC/MS/MS tests. It is important to note that the choice of testosterone test should be made in consultation with a healthcare professional. They can guide you in selecting the most appropriate test based on your specific needs, medical history, and the accuracy and reliability of the available testing methods. How to Choose the Right Testosterone Test for You Choosing the right testosterone test depends on your needs and talking with a healthcare provider. Your medical history, symptoms, and the possible cause of hormonal issues are important in selecting the best test. A good first step is the total testosterone test. This test checks the total amount of testosterone in your blood. If the first results show any issues, a free testosterone test might be suggested. Free testosterone is the active part of the hormone that your body can use easily. Working together with your healthcare provider helps in picking a testosterone test. This way, you can get the best information to help with your health concerns. The Importance of Accuracy and Reliability in Test Results When you get testosterone tested, it is very important to have test results that are accurate and reliable. If the results are wrong, it can cause misdiagnoses, lead to bad treatment plans, and create unnecessary stress. You should pick testing providers that care about quality control. If you use at-home testing kits, carefully follow the instructions. Proper sample collection is key to reducing mistakes. Talk about any worries regarding test accuracy and reliability with your healthcare provider. They can help you understand your results and suggest trusted testing facilities, if necessary. Before You Buy: Understanding Testosterone Tests Beginning the journey of testosterone testing means you need to understand what these tests are and why they matter for men's health. Testosterone tests check the amount of testosterone in the blood. This hormone plays a key role in male sexual growth and function. Before getting a test, it is important to know the different types of testosterone tests. You should also understand what information they can provide and what things might affect test results. Deciphering Test Results: Free Testosterone vs. Total Testosterone Interpreting testosterone test results means knowing the difference between free testosterone and total testosterone. Total testosterone shows the overall amount of testosterone, while free testosterone shows the part that is active and works in the body. A normal range for total testosterone in adult males is usually between 300 and 1,000 nanograms per deciliter (ng/dL). This range can change a bit based on the lab. Free testosterone usually makes up about 2% of total testosterone. When looking at test results, it is important to think about both free and total testosterone levels. You should also consider your age, your overall health, and any symptoms you may have. A healthcare provider can help you understand your results and decide on the next steps. Preparing for Your Testosterone Test: Do's and Don'ts To get accurate and reliable testosterone test results, you need to follow certain preparation steps. These steps help reduce the effect of things outside your control that might change the results. Here’s a list of do's and don’ts to remember: Do's: Schedule the test for the morning. This is when testosterone levels are usually at their highest. Follow the fasting rules for testosterone testing. Breakfast can temporarily reduce testosterone levels, leading to misleading test results. Don'ts: Avoid heavy exercise. Hard workouts can raise testosterone levels for a short time. Don't drink alcohol. Alcohol can affect hormone levels and change the results. By following these tips, you can help ensure that your testosterone test shows the true state of your hormones. This will help you make better health choices. When to Consider Retesting: Timing and Frequency The time for testosterone testing depends on your situation and why you were first tested. If you had testing done to find a specific issue or to check how well treatment is working, your healthcare provider might suggest regular retesting. If your testosterone levels are normal and you have no major symptoms, you may not need to retest right away. Still, checking periodically is a good idea, especially as men get older. This helps keep track of any changes in hormones and can help catch issues early. Changes in your lifestyle, medications, or new symptoms could mean you need to test again. It's important to talk to your healthcare provider about a plan just for you. This way, you can take the best steps to keep your hormonal health in good shape. Interpreting Your Testosterone Test Results: A Comprehensive Guide Understanding testosterone test results involves looking at many factors that can affect hormone levels. It's important to talk to a healthcare provider for accurate reading and advice that suits you. Labs usually give a reference range for normal testosterone levels. These ranges might be a little different from one lab to another. Also, your personal situation plays a part in determining what levels are best for you. Factors such as age, overall health, medications, and any symptoms matter when thinking about what your results mean. It is important to note that test results are interpreted in the context of your specific health situation, and your doctor may recommend repeat testing or additional tests to learn more about what may be causing your symptoms and/or the change in your testosterone level and potential medical conditions, such as polycystic ovary syndrome (PCOS). Your healthcare provider will look at these factors along with your test results to check for any hormone issues. Next Steps: Managing Low or High Testosterone Levels Once you get your testosterone test results, what you do next depends on whether your levels are normal or not. If your levels are outside the normal range, your healthcare provider will suggest a plan made just for you. If you have low testosterone levels, testosterone replacement therapy (TRT) might be a good choice. TRT adds testosterone to your body using different methods like injections, gels, patches, or pellets. Sometimes, treating other health issues like obesity, diabetes, or thyroid problems can boost testosterone production. How to Find a Good Testosterone Doctor. Maximizing Savings on Testosterone Tests Taking care of your health doesn't have to cost a lot. There are many ways to save money on testosterone tests and still get good quality and accurate results. You can start by knowing what your insurance covers. You can also look into other testing choices. By taking charge of your testing costs, you can focus on your health while keeping an eye on your budget. Leveraging Health Insurance and HSA/FSA Accounts Maximizing your health insurance benefits and using tax-advantaged accounts like Health Savings Accounts (HSAs) or Flexible Spending Accounts (FSAs) can help you save money on testosterone testing. Before you have any tests done, check your health insurance policy or speak to your provider. This will help you find out if testosterone tests are covered. Some plans may cover everything for diagnostic reasons, while others might require you to pay part of the cost or meet a deductible. If you have an HSA or FSA, you can often use that money to pay for eligible costs, including testosterone testing. This can further lower your out-of-pocket expenses. By knowing how to use these financial tools well, you can make healthcare easier to access. Conclusion In conclusion, it is important to maintain balanced testosterone levels for the health and well-being of men. There are many online options for testosterone testing. You should look through them to find the best one for your needs. Keeping track of your test results can help you manage any imbalances effectively. When choosing a testosterone test provider, consider things like accuracy, reliability, and cost. By staying informed and active about your testosterone levels, you can improve your overall health. Start exploring the various testosterone testing options online for a better journey toward health. Frequently Asked Questions What is the average cost of a testosterone test online? The cost of a testosterone test online can change quite a bit. Usually, prices are between $49 and $200. This depends on the lab, the type of test, and any extra services offered. To understand the prices in your area better, it's a good idea to talk to your healthcare provider or look at online lab websites. How often should I check my testosterone levels? The amount of testosterone testing needed varies from person to person. It depends on your health and specific situation. Your healthcare provider can help you decide how often to get retested. They will consider things like your age, symptoms, and any health issues you may have. Can I trust the accuracy of online testosterone tests? The accuracy of online testosterone tests can change based on the provider and the type of test. Choose reliable online labs that work with certified labs and focus on quality. For extra comfort, talk about your test results with your healthcare provider. Are there any risks involved with testosterone testing? Testosterone testing is safe, whether you do it in a lab or with an at-home kit. There can be small risks, like bruising, bleeding, or infection, where the sample collection happens. These issues are rare and usually not serious. If you have any worries, talk to your healthcare provider.

Nelson Vergel, author of Testosterone: A Man's Guide (Amazon.com) and founder of ExcelMale.com and DiscountedLabs.com, talks about what he thinks are the 10 most important things that all men on testosterone replacement therapy should know to maximize benefits and minimize side-effects. For questions for Nelson, please register on ExcelMale.com and post them on the forum page. For more detailed information about what blood test parameters are important to monitor while on testosterone replacement therapy, read: Testosterone Replacement Blood Test Targets and Their Management For blood tests to buy to monitor your testosterone replacement, check these lab test panels: Pre TRT Lab Test Panel TRT MALE Hormone/Wellness Follow Up Panel   Find out more about testosterone replacement therapy and what tests to perform   Video Transcript:   Hi everybody. Nelson Vergel with ExcelMale.com. Somebody gave me a really good idea on ExcelMale.com. It's a forum of over 14,000 members. We discuss everything related to testosterone replacement, nutrition, exercise, supplements, and other options like Trimix, hCG, and estradiol, et cetera. Somebody asked me, "Nelson, why don't you do a video of Nelson's Top 10 TRT Commandments?" And this is what I'm doing today. So, I'm going to include the different observations and suggestions I have after reading over 40,000 posts over the last three years on ExcelMale.com.   Testosterone is not a magic bullet.   The first one is testosterone is not a magic bullet, and I remind guys who have high expectations when they start testosterone replacement because they have low testosterone that things may improve in many ways, like improvements in sexual function and sex drive, energy, cognitive function, et cetera. But sometimes they may not improve as much as you expect because there are many factors involved, especially in sexual function, libido, and desire. I have another presentation or lecture that I did on the subject, so you can check it out on ExcelMale.com, or on the YouTube channel, also named ExcelMale.com. But there are over 12 factors involved in the sexual desire in men. Testosterone is one of them, obviously, so fixing the low testosterone issue tends to improve things in that department. However, if you're not sleeping well, if you have excessive weight, if you're drinking too much, if you have some illnesses like diabetes or cardiovascular disease, and if you're taking medications that may influence sex drive and erectile function like blood pressure medications, antidepressants, et cetera, you may not get all the benefits that one would expect from testosterone. So, check out that video, and I will get into more details on that subject.   Do not obsess about estradiol.   The second one is the second commandment: do not obsess about estradiol. Estradiol has become the hottest topic of discussion in men's health forums, and it's a topic that is filled with misconceptions and a lot of speculative information. We have data that shows that estradiol is a very important hormone in men. It is produced from the aromatization of testosterone into estradiol by aromatase enzyme in the liver and in fat cells. The body actually produces it for a good reason. There's a good reason why nature put estradiol downstream of testosterone. We need estradiol for bone health, cognitive health, sexual function, and drive, and even keeping good body composition and cardiovascular health.   A lot of men tend to freak out when they start testosterone and they think everything is related, all the side effects are related to high estradiol. Biggest problem I see is that very few men are actually testing their estradiol. Doctors are not monitoring estradiol levels, and if they are, they're using the wrong tests. They're using the immunoassay instead of the liquid chromatography/mass spectrometry assay. The former basically overestimates estradiol. Secondly, water retention and/or nipple sensitivity may have nothing to do with estradiol blood levels. So, men are jumping into starting treatment with an AI, when in fact their estradiol is under 40 picograms per milliliter, and they don't really need to be taking it.   Many crash their estradiol blood levels under 20 mg and they started losing sex drive and they start even getting fatter, because it's being studied in research that that's the case. So, do not obsess about estradiol. Estradiol is not an evil hormone. Estradiol is in our body for a reason. Do not over treat with anastrozole. I'm telling doctors, be very careful. They are giving people high doses, over 1mg a week of anastrozole to men. I'm also really concerned that many clinics out there, and I hope they're listening to me, are starting men on anastrozole at baseline when the fact is, they should have waited or they should way until follow up, after six or eight weeks follow up, and test the men's estradiol after they start testosterone replacement. And then, and only then, determine whether or not they have high estradiol over 40.   And as our testosterone blood levels increase, so does estradiol. Only 0.4% of testosterone becomes estradiol, so it's only logical that we should have higher estradiol when we have obviously higher testosterone levels because of injections or gels or creams or pellets. So that's my biggest concern out there. Estradiol is not an evil hormone and we need it. Do not obsess. Do not put all your ... do not blame it on all the side effects, especially if you're not testing the blood levels.   Monitor your hematocrit.   Your hematocrit. Monitor your hematocrit, is number three, very closely during the first six to eight months. Hematocrit is the proportion of the blood, the blood volume, that is made up of red blood cells. Testosterone replacement increases the production of red blood cells, which is a good thing if you have anemia. However, overproduction of red blood cells and an increase of hematocrit obviously, can increase the viscosity of the blood, and that can lead to cardiovascular risks and events. So, doctors pretty much monitor this parameter using a very cheap panel called the CBC, the cells and chemistry, cell count and chemistry profile. Very cheap. I think you can buy it on discountedlabs.com for $29, and that includes hematocrit. As your hematocrit starts climbing up closer to 52, it is time for you to go and donate blood at a blood center. What I'm seeing, I'm seeing a few problems there. I'm seeing men waiting too long so they get to 53, 54 in hematocrit and they get rejected for donations because the Red Cross and different blood centers have a limit of 53. So do not wait too long, otherwise you are not going to be able to donate blood for free.   If you do wait that long and your hematocrit is 53, 54, 55, whatever,. I've seen guys walking around with a 65, which is crazy. That's when doctors don't monitor that. Very upsetting. Anyway, if you get to those high levels, you're rejected by the nation and you will need an order from your doctor, like a prescription. Your doctor calls in any blood center and you may have to pay for the phlebotomy. It's called a therapeutic phlebotomy. You would probably have to pay. Many centers charge over $100. So, do not wait too long. Do not donate blood or do therapeutic phlebotomies more frequently than every three months, because that has been shown to decrease iron levels and ferritin, which may make you fatigued. So, if you are by any chance one of those unlucky men that really produces a lot of red blood cells, you may have your doctor check your iron or ferritin after you donate blood. If they are low, you can take an iron supplement for a few weeks until it's normalized.   The high hematocrit issue does not happen to everybody. Most men have a bump around three to four points higher. Most of the time, hematocrit stabilizes after 18 months. For instance, I've been using testosterone for over 34 years, and I've only donated blood once, and usually it's within the first six months that you know whether or not your hematocrit will be increasing. After six months, chances are... unless you increase the dose of testosterone, obviously, that you will stay pretty much stable there. So, it's not a long-term concern.   Inject testosterone using easier methods: subcutaneous or shallow IM.   Okay, the next commandment is exploring easier ways to inject, subcutaneously, shallowly, or IM, which is shallow intramuscular injections. The old way of injecting testosterone with a big old syringe of one and a half inches on your glutes or quads is pretty much gone. There is no need to suffer through painful injections with big needles anymore. We have good data that shows that subcutaneous injections under the skin with a very tiny, half-inch, 27-gauge, or even 29-gauge syringe are enough to get the body to absorb and get the blood levels up. So, there is no need to suffer. I inject in the shoulders at 90 degrees with a 27-gauge, one-inch... I'm sorry, half-inch syringe, and it's basically painless. Also, inject twice a week instead of injecting once a week. We are moving from the world where doctors were prescribing testosterone at 200 mg every two weeks to 100 to 150 mg, depending on the blood levels that you need, every week to 50 to 75 mg every two weeks. So, there are clinics that are prescribing it once a week, but there's nothing wrong with that. I really believe so. But many clinics are now splitting the dosage in two and also bringing in something called hCG, which I will talk about.   So, do not suffer. Do not dwell anymore with big needle syringes. You can inject under the skin. You can inject shallow, at half an inch, anywhere in the quads, delts, or even the glutes. And that will basically ensure that most of us adhere to a long-term therapy like testosterone replacement. As you all know, testosterone replacement is a long-term commitment—a lifetime commitment. Never cycle testosterone on and off.   The next commandment is obviously to never cycle testosterone replacement on and off. This is a lifetime commitment. If you stop testosterone replacement, your blood levels will crash. You will not produce testosterone for a while. People tend to email me to ask me how many weeks they're going to be in that situation. It is impossible to predict, impossible to predict. Some studies on bodybuilders have shown that it takes probably as long as you were on testosterone to get back to your baseline. Remember, all of us who started testosterone replacement had low testosterone at baseline. That's why we got into testosterone replacement. So even if your body tends to readjust after a few weeks and bring you back to what you used to be, you're probably going to have low testosterone. So, that's a discussion that I don't see doctors doing very well with patients that are about to start therapy. The fact that it is a commitment. No, you're not going to die if you stop testosterone. It is true that you're going to have a rough time with low libido, energy, and cognitive function for a few weeks, but things will move on and you'll basically go back to where you used to be before testosterone. Know your TRT blood tests.   The next one is knowing your blood tests and your schedule for blood testing. Yes, your doctor is supposed to remind you when you're supposed to get blood tests done, but it's not brain science; it's not rocket science. On ExcelMale.com, on discountedlabs.com, which is my company, my lab test company, you can get tests online anywhere in the United States, with exception to New York State, New Hampshire, and Massachusetts. Basically,  the northeastern states have passed legislation to limit options for consumers there, but in most states, you can go to discountedlabs.com, order your test there, pay by credit card or PayPal, and then we will email you the results after five to seven days when you give your blood at the lab or location closer to you.   You can check the scheduling for testosterone blood testing and monitoring on ExcelMale.com, also through one of my videos that I made on that subject, and also on the blog page of discountedlabs.com. But know, at least, that you have to have certain blood levels tested at baseline. The doctor will probably have you come in six to eight weeks later, just to see if a dosage is good enough for you. We'll ask you about all your symptoms to see if they're getting better. They may check not only hematocrit, estradiol, or other hormones but also see whether you need a readjustment or treatment with anastrozole, like I said before. So, it is also important to tell the doctor when you got your blood test done, your blood draw, because some guys forget that you should be getting your blood drawn right before your next injection. I'm talking about injections. Gels and creams are different because, since we're using the same dosage every day, it doesn't really matter when you get the blood drawn.   Do not change more than one variable at a time. The next one is do not change more than one variable at a time, and I do remind everybody on ExcelMale. We are all kind of our own guinea pigs. Everybody has to experiment on themselves. Every time we start something, we can change the dosage, the frequency, or other things, but we cannot change more than one variable if you want to measure the impact of that change on your quality of life. And that's one of the biggest problems I'm seeing. Some guys start changing things around and then they forget what worked and what didn't. I know it's a basic concept, but we all get very impatient, and that's another thing I'm seeing: the expectations are not well-described by doctors at baseline. So, we start changing things around without telling the doctor, and then obviously everybody's lost. You and the doctor are lost.   So, one variable at a time. It takes a while to do that. To be a good guinea pig with good experimentation, good dosage adjustment, et cetera, it takes a while. It takes like six months average to get to that point where you say, "Okay, I'm pretty much in the dosage I need to be, frequency I need to be, anastrozole dosage if I need, hCG," which I'll be speaking about hCG, et cetera, et cetera. So, don't be impatient. I know most of us who are getting onto testosterone replacement are a little desperate. We are not feeling that great; our relationships are hurting because of sexual dysfunction or things like that, and we need a quick fix. It is not a quick fix. It takes a while, but generally, you will have good results if you do it well   You can’t change what you don’t measure.   The next one is that you can't change what you can't measure. I remind people, even I forget how I felt last week. And when you're going to the doctor, you haven't seen the doctor in eight weeks or 12 weeks, and the doctor asks you how you have been feeling? You're pretty much are going to say how you've been feeling the past few days, since you remember that. So, I kept that in mind and we created an app, available on the Apple Store or on Google Play, called TRT Analyzer. That app basically sends you a text message or a message during the day to ask you how you felt, and there are different variables like fatigue, exercise intensity, libido, if you had a morning erection, et cetera. And then you can graph. Inside the app, there's a graphing option and you can actually email the graphs to your doctor, even print them, and bring them to your next office visit. That will show basically what happened in the last 12 weeks or eight weeks that you haven't seen the doctor.   So, doctors love it because it helps them. It helps them. They actually score with the graph on every single parameter. So TRT Analyzer. Download it for free. There's been over 600 downloads this month, so we're very happy. Another site that I created is called myhealthgraphs.com. Myhealthgraphs.com. We'll probably be changing it into an app too. But it's a website. It's not an app. It's a website where you can add your blood test results, whatever you're following: testosterone, estradiol, hematocrit, et cetera, and it will also plot values for your doctor to see too. Doctors are busy. Doctors need people who save them time. Doctors tend to treat patients that save them time better than those that do not save them time. Doctors are human beings. They are really busy with a lot of pressure, and we walk into a doctor's office expecting the doctor to remember everything we told them last time. Even though it's written, some of them don't even have time to read the notes that they made from last time.   So, be a good patient and monitor everything; chart everything. Bring your reports on how you feel to the doctor. Believe me, you're going to get treated better than those who do not. The same doctor can treat two different patients differently just based on that behavior. I wish I had data to show, but it's my speculation.   Protect your testicles.   The next commandment is protecting your testicles, fertility, and upstream hormones. Talk to your doctor about hCG, or human chorionic gonadotropin. I made a video also on hCG, so check it out also on ExcelMale.com or the ExcelMale YouTube channel. But the thing about testosterone replacement when we started was that our testicle Leydig cells shut down. They don't produce testosterone anymore and they also start decreasing their production of sperm and our fertility gets really impacted, especially if we are obviously looking forward to having another kid with your wife or your girlfriend. So, that's a concern. Many doctors wrongly make patients stop testosterone replacement when they want to have a kid, which is a horrible thing to do. Instead, we have now some data from Baylor College of Medicine, Lipshult’s team, that shows that using testosterone and hCG together can prevent not only the atrophy of the testicles, or the shrinkage of the testicles, but also improve fertility.   Lately, we have gotten some data on the fact that hCG can reactivate all the hormones that are upstream of testosterone that were shut down by testosterone replacement. Testosterone replacement is obviously a good thing to do, but it shuts down LH, FSH, pregnenolone, progesterone, and even DHEA in many cases. So, all those hormones upstream tend to be reactivated by the effect of hCG. I'm going to get into many details on that because I have a video in which, actually, I think I drew a diagram on a whiteboard so that you can understand more of what I am trying to say. Because a lot of doctors say, "No, I don't prescribe hCG. I think there's no use for that," and I think after you watch that video, you will be able to negotiate with your doctor about the use of hCG in a much more educated fashion.   Don’t stay behind on TRT advances.   The next commandment is: don't stay behind on advances. Actually, that's the last commandment—the 10th one. And this is an evolving field—testosterone replacement and men's health in general. We don't only talk about testosterone on ExcelMale.com. We talk about thyroid hormones, about DHEA, about pregnenolone and progesterone, about supplements, about exercise, about, you name it, diet, even some cognitive practices, et cetera. It's really amazing how many studies are coming through every week, and even for me, I read everything that I can every day. Even before going to bed, I print out a few papers. Even for me, it's hard to keep up, and I know that if I'm not staying current, I may be missing things that are coming through in the field and obviously will not be able to help others with my information. But don't stay behind on advances. Register on ExcelMale.com and learn more, because an educated patient pretty much gets a lot better care.   So, thank you so much for watching this video.  Subscribe to the ExcelMale YouTube channel and register on ExcelMale.com. Thank you.    

Are you a bodybuilder looking to maximize your performance and ensure optimal health? Regular bodybuilding blood work is key to achieving these goals. It provides valuable insights into your body's functioning, allowing you to make informed decisions about your training, nutrition, and supplementation. In this blog, we will explore the importance of regular blood work for bodybuilders and how it can help you strike the right balance between performance and health. We'll also address common factors that can affect blood test values in bodybuilders, as well as essential lab tests that every bodybuilder should consider. Don't miss out on this valuable information that can take your bodybuilding journey to new heights. Table of Contents The Importance of Regular Bodybuilding Blood Work Maximizing Performance and Health: A Balance Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care Factors that Affect Blood Test Values in Bodybuilders Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Resistance Exercise Can Increase Liver Enzymes Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol High Doses of Anabolics Can Decrease Ferritin in Bodybuilders Understanding Essential Bodybuilding Blood Work Tests Complete Blood Count (CBC) Hematocrit Comprehensive Metabolic Panel (CMP) Lipid Test Panel Cystatin C with EGFR Kidney Test eGFR Kidney Test GGT Liver Test Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Free Testosterone (Equilibrium Ultrafiltration) Test Ultra-Sensitive Estradiol (E2) Test Prolactin Test DHT Test IGF-1 Test Ferritin Test How do these tests help optimize bodybuilding performance? The role of these tests in muscle gain, fat loss, and quality of life How can bodybuilders prepare for these tests? Why is regular bodybuilding blood work essential? How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com Conclusion   The Importance of Regular Bodybuilding Blood Work Regular bodybuilding blood work plays a crucial role in monitoring hormone levels and overall health, including high blood pressure. By conducting regular blood tests, bodybuilders can identify potential health issues before they become serious. Additionally, blood work provides valuable insights for optimizing nutrition and supplementation, leading to better performance. Tracking blood markers allows bodybuilders to make informed decisions about their training and recovery strategies. Ultimately, regular blood work is essential for long-term health and longevity in the world of bodybuilding. By staying on top of blood markers like testosterone, hormone levels, glucose, and kidney function, bodybuilders can ensure they are in optimal condition to achieve their goals. Maximizing Performance and Health: A Balance Regular monitoring of bodybuilding blood work, including testosterone tests, is crucial for bodybuilders to maximize their performance and maintain good health. Through regular blood tests, bodybuilders can monitor hormone levels, nutrient deficiencies, and overall organ function. This information is invaluable in making informed adjustments to diet, supplements, and training routines. By maintaining a balance between performance and health, bodybuilders can optimize their training and achieve their goals. Prioritizing health through regular blood work is essential for long-term success and sustainable progress in bodybuilding. It allows bodybuilders to identify any potential imbalances and make the necessary adjustments for optimal performance. By utilizing comprehensive metabolic panels, lipid panels, and hormone level tests, bodybuilders can ensure that their training is effective and their bodies are functioning optimally. Ergogenic Effects Associated with Anabolic Steroids and High TRT Doses   According to a scientific review, the use of anabolic steroids has the following ergogenic effects: ■ Increase in lean body mass ■ Increase in muscle cross-sectional area ■ Decrease in body fat percent ■ Increase muscle strength & power ■ Enhance recovery between workouts ■ Enhance recovery from injury ■ Increase in protein synthesis ■ Increase in muscle endurance ■ Increase in erythropoiesis, hemoglobin, and hematocrit ■ Increase in bone mineral density ■ Increase in glycogen storage ■ Increase in lipolysis ■ Increase in neural transmission ■ Reduced muscle damage ■ Increase in pain tolerance   However, the use of these agents could have the following side effects: Cardiovascular ■ Lipid profile changes ■ Elevated blood pressure ■ Decreased myocardial function Increased in blood viscosity due to high hematocrit Dermatological ■ Acne ■ Male pattern baldness Endocrine ■ Gynecomastia ■ Decreased sperm count ■ Testicular atrophy ■ Impotence and transient infertility Hepatic ■ Increased liver enzymes Renal Decreased kidney function Genitourinary Males ■ Reduced sperm counts ■ Decreased testicular size Females ■ Menstrual irregularities ■ Clitoromegaly ■ Masculinization Males and Females ■ Gynecomastia ■ Libido changes Physician Stigma About PEDs Keeps Bodybuilders From Seeking Care The stigma surrounding performance-enhancing drugs (PEDs) frequently makes bodybuilders reluctant to seek medical attention. Many bodybuilders are reluctant to disclose their PED use due to fear of judgment or a lack of understanding from healthcare professionals. This can impede their access to important resources such as regular blood work, which is vital for monitoring health and performance. Healthcare professionals need to be knowledgeable about the potential risks and side effects associated with PEDs in order to provide appropriate care and guidance. Open communication and support between bodybuilders and healthcare professionals can foster collaboration for optimizing performance while minimizing health risks.   Factors that Affect Blood Test Values in Bodybuilders Muscle damage and inflammation can impact blood test results in bodybuilders, as the body's response to intense training can cause temporary changes in certain blood markers. Additionally, high protein intake, which is common among bodybuilders, may affect kidney function and liver enzymes but is not clinically significant, which is concerning to doctors not familiar with this fact. Steroid use can also lead to hormonal imbalances and abnormal blood test results. Dehydration, which can occur during intense workouts or when bodybuilders are cutting weight, can cause changes in electrolyte and blood cell levels. Weight training can also increase certain live enzymes in a non-clinical way. Supplements like creatine can falsely increase serum creatinine, which can alarm certain physicians. It is important for bodybuilders to address any nutritional deficiencies identified through blood testing, as these deficiencies can impact performance and overall health. Anabolic Steroid Use Without Testosterone Can Decrease Testosterone Blood Levels Anabolic steroid use without testosterone can result in a decline in testosterone levels among bodybuilders, leading to low testosterone, or TSH. Testosterone plays a crucial role in muscle growth, recovery, and overall performance in bodybuilding. To ensure optimal health and performance, bodybuilders should regularly monitor their testosterone levels. Consulting with a healthcare professional can help them effectively manage their hormone levels. It is essential to maintain balanced testosterone levels to avoid negative side effects and maximize results. By being proactive in monitoring testosterone levels, bodybuilders can optimize their performance and achieve their desired outcomes. Resistance Exercise Can Increase Liver Enzymes Intense resistance exercise can result in temporary elevations in liver enzymes, including alkaline phosphatase, which is a normal response to muscle damage and repair. It is crucial for bodybuilders to inform their healthcare provider about their exercise routine before getting blood work done. Although elevated liver enzymes due to exercise are typically harmless and resolve on their own, regular monitoring of liver enzymes is essential for bodybuilders to ensure optimal health and performance. By keeping track of liver enzyme levels, bodybuilders can identify any abnormalities early on and take appropriate actions to maintain their liver function. Creatine Supplementation Can Cause Artificial Decreases in Kidney Function as Measured by Creatinine Creatine supplementation can temporarily decrease kidney function markers, leading to lower creatinine and potassium levels in bodybuilders. It is important for bodybuilders to inform their healthcare providers about any dietary supplements before undergoing blood tests. Once creatine supplementation is discontinued, creatinine and potassium levels can normalize. However, monitoring kidney function through multiple biomarkers is essential for an accurate assessment. By incorporating these measures, bodybuilders can ensure that their kidney function is accurately evaluated. Some Oral Anabolic Steroids and Supplements Can Increase Liver Enzymes and Decrease HDL cholesterol Certain oral anabolic steroids used by bodybuilders have the potential to increase liver enzymes and decrease HDL cholesterol levels, leading to an increase in total cholesterol and low-density lipoprotein. Regular blood tests are vital for bodybuilders who use these oral steroids to monitor their impact on liver function and cholesterol levels. Elevations in liver enzymes can be a sign of liver damage, while decreased HDL cholesterol levels pose a risk for cardiovascular health. Working with a healthcare professional is essential to mitigating these potential risks associated with the use of oral anabolic steroids. By closely monitoring liver health and cholesterol levels, bodybuilders can make informed decisions about their supplementation and take necessary steps to protect their overall health. High Doses of Anabolics Can Decrease Ferritin in Bodybuilders High doses of anabolic steroids can result in decreased ferritin levels among bodybuilders, impacting their overall performance. Ferritin plays a crucial role as a protein that stores iron, and deficiencies can have negative effects on muscle growth and health. To optimize supplementation and monitor ferritin levels, regular blood tests are essential. Consulting with a healthcare professional can provide personalized guidance on maintaining optimal ferritin levels and growth hormone levels. It is important for bodybuilders to be aware of the potential impact of high doses of anabolic steroids on ferritin levels and take proactive measures to ensure balanced hormone levels and nutrition. By prioritizing the monitoring of ferritin levels, bodybuilders can support their muscle growth and overall well-being. Understanding Essential Bodybuilding Blood Work Tests Regular blood work is vital for bodybuilders to monitor their health and optimize their performance. Key lab tests for bodybuilders include hormone levels, liver function, kidney function, and thyroid function. These tests can help identify potential health issues and allow for adjustments in training and nutrition plans. Working with a healthcare professional who specializes in sports medicine or bodybuilding is beneficial to ensure an accurate interpretation of the results. By regularly monitoring hormone levels, such as testosterone and estradiol, bodybuilders can address any imbalances and make necessary adjustments to their supplementation or hormone replacement therapy. Additionally, liver function tests like ALT and AST can assist in identifying any liver abnormalities or damage that may result from the use of anabolic steroids. Kidney function tests, like creatinine and BUN, are crucial for assessing the impact of intense training and supplement use on the kidneys. These lab tests provide valuable insights into a bodybuilder's health and play a crucial role in maintaining optimal performance, including CMP. Complete Blood Count (CBC) A complete blood count (CBC) test panel measures several components of your blood, including Red blood cells, which carry oxygen, White blood cells, which fight infection; hemoglobin, the oxygen-carrying protein in red blood cells; hematocrit, the proportion of red blood cells to the fluid component in your blood (which is correlated with blood thickness); and Platelets, which help with blood clotting. Hematocrit All androgens, like testosterone and AAS, can increase red blood cells and their proportion in the blood (hematocrit), increasing blood thickness (erythrocytosis). High hematocrit can cause high blood pressure, headaches, and cardiovascular risks. This panel is essential since it determines when you reach a hematocrit of 53, indicating that blood donation or therapeutic phlebotomy is needed. Comprehensive Metabolic Panel (CMP) The comprehensive metabolic panel, or CMP panel, consists of 14 blood tests that are an initial medical screening tool to review overall health. The CMP blood test panel checks for glucose, kidney function, liver function, electrolytes, and fluid balance. Fasting IS REQUIRED. Lipid Test Panel This panel includes LDL (bad cholesterol), HDL (good cholesterol), and triglycerides (fatty acids dissolved in the blood). Higher doses of T and AAS can increase LDL and decrease HDL and triglycerides. Severely decreased HDL may cause cardiovascular issues in the long term. FASTING IS REQUIRED. Cystatin C with EGFR Kidney Test Since higher muscle mass, protein intake, and creatine supplementation can all affect creatinine as the primary variable, cystatin C is a more accurate way to assess kidney function in people with higher muscle mass. Another one of the measures of kidney function is the estimated glomerular filtration rate (eGFR). The glomerular filtration rate describes the flow rate of filtered fluid through the kidney. Creatinine clearance rate (CCRCr or CrCl) is the volume of blood plasma that is cleared of creatinine per unit of time and is a useful measure for approximating the GFR. eGFR under 60 may indicate issues that are affecting kidney function. eGFR Kidney Test The eGFR kidney test is an important tool for bodybuilders to monitor their kidney health and ensure optimal performance. By measuring how well the kidneys are functioning, this test can help detect any potential kidney issues that may arise, affecting metabolism. It is crucial for bodybuilders to regularly check their eGFR levels, as low levels under 60 can indicate kidney damage or impaired kidney function, which can have a negative impact on performance. Maintaining a healthy eGFR level is essential for overall health and athletic performance. Consulting with a healthcare professional is recommended for interpreting eGFR results and taking the necessary steps to support kidney health. GGT Liver Test The GGT blood test looks for an enzyme, or protein, called gamma-glutamyl transpeptidase (GGT) in your blood. GGT is found in liver cells. This test helps your doctor look for damage to your liver or its ducts. It can also help tell the difference between liver and bone disease if your results from a different blood test called alkaline phosphatase are abnormal. Higher than-average test results could indicate liver damage from diseases such as hepatitis, cirrhosis, tumors, or pancreatic cancer. The good thing about GGT (unlike liver enzymes included in the CMP like AST and ALT) is that resistance exercise does not affect its value, so it is a more accurate way to detect liver disease in bodybuilders. Total Testosterone by Liquid Chromatography/Mass Spectrometry, plus Free Testosterone by Equilibrium Ultrafiltration. Men with high testosterone cannot use the regular total testosterone test based on immunoassays since it has an upper limit of 1,500 ng/dL. The LC/MS testosterone test does not have an upper limit. Also, some labs offer calculated free testosterone instead of the equilibrium ultrafiltration-based one, which is more accurate for this critical variable. Free Testosterone (Equilibrium Ultrafiltration) Test The equilibrium ultrafiltration test is a precise method used to measure the amount of unbound testosterone in the bloodstream. Free testosterone plays a crucial role in muscle growth, strength, and overall performance for bodybuilders. Monitoring free testosterone levels can provide valuable insights into potential imbalances or deficiencies that may impact training, recovery, and hormone balance. By regularly testing free testosterone, bodybuilders can optimize their training and supplement plans to maximize their performance and health. This test, along with other essential lab tests, helps bodybuilders maintain optimal hormone levels and ensure their body is functioning at its best. Ultra-Sensitive Estradiol (E2) Test The commonly used estradiol test may overestimate estradiol. That test uses immunoassay technology that cannot differentiate C-Reactive Protein (involved in inflammation) from estradiol, so it reads the combination of the two as estradiol. This ultrasensitive estradiol test is based on liquid chromatography/mass spectrometry (LC/MS), an assay technology that does not have that limitation. Furthermore, DHT analogs like oxandrolone may dramatically decrease estradiol, causing joint aches and other low estradiol issues. Note: 0.4 percent of total testosterone aromatizes to estradiol. This is the body's way of balancing testosterone's negative effect on lipids with estradiol's beneficial effect. If your total testosterone is high, so is your estradiol. Be very careful in assuming that an aromatase inhibitor is needed. For more information, click on the effect of high and low estradiol on men's health. How to predict estradiol for different testosterone doses. Prolactin Test Many bodybuilders worry about increased prolactin since it has been associated with erectile dysfunction. Regular monitoring of hormone levels is essential for bodybuilders, and the prolactin test plays a crucial role in this process. This test helps detect potential imbalances that can impact performance and overall health. Elevated prolactin levels may indicate issues such as reduced testosterone production or the presence of pituitary gland tumors. Therefore, it is vital for bodybuilders to undergo regular prolactin testing to optimize their performance and maintain their overall well-being. However, interpreting the results accurately requires consultation with healthcare professionals. By keeping prolactin levels in the optimal range, bodybuilders can enhance muscle growth, support recovery, and promote their overall physical and mental well-being. DHT Test This test measures the amount of dihydrotestosterone (DHT) in the blood. Low DHT has been associated with low libido, and high DHT has been linked to acne, hair loss, and benign prostatic inflammation in a minority of men. DHT test (LC/MS) measures dihydrotestosterone levels, a hormone linked to muscle growth and male characteristics. It helps bodybuilders evaluate hormonal balance for enhanced performance. Monitoring DHT levels provides insights into potential side effects or risks associated with supplements or steroid use. Regular testing tracks progress and informs decisions on training and supplementation. Discussing results with healthcare professionals creates personalized strategies for goals. IGF-1 Test Insulin-like Growth Factor 1, also known as IGF-1, is used as a biomarker for blood levels of human growth hormone. It is a hormone that the liver and other tissues produce that affects glucose metabolism and growth-promoting activities. Low IGF-1 may impede muscle growth. The IGF-1 test, performed using LC/MS, is a crucial tool for bodybuilders to assess their performance and overall health. This test measures the levels of insulin-like growth factor-1, a hormone that plays a vital role in muscle growth and repair. By analyzing IGF-1 levels, bodybuilders can determine whether they have optimal hormone levels for performance and recovery. Low levels of IGF-1 may indicate potential limitations in muscle growth or underlying health issues. Ferritin Test Ferritin is a protein that stores iron. Red blood cells need iron to form and carry oxygen around your body. Low levels of ferritin lead to anemia. TRT and anabolic steroids make the body make more red blood cells (erythrocytosis). This increased production decreases iron stores and ferritin. Testosterone has been shown to decrease ferritin. Men who use TRT and anabolic steroids and have high hematocrit (increased blood thickness due to TRT or anabolic steroids) frequently donate blood or undergo therapeutic phlebotomy to lower hematocrit. There is a loss of around 30 points of ferritin during every donation. Low ferritin can cause fatigue, restless leg syndrome, muscle aches, and other issues. How do these tests help optimize bodybuilding performance? Bloodwork tests play a crucial role in optimizing bodybuilding performance. They provide valuable insights into hormone levels, nutrient deficiencies, and overall health. By identifying imbalances or deficiencies, bodybuilders can make targeted adjustments to their diet and supplementation, enhancing muscle growth, recovery, and overall performance. Regular blood work helps track progress and make necessary adjustments to training and nutrition protocols. The role of these tests in muscle gain, fat loss, and quality of life Blood tests play a vital role in bodybuilding, specifically when it comes to muscle gain, fat loss, and overall quality of life. These tests provide valuable insights into hormone levels, such as testosterone and cortisol, which are crucial for optimal muscle growth and fat loss. By monitoring these blood markers, bodybuilders can optimize their recovery and prevent overtraining. Additionally, blood work can reveal any nutrient deficiencies that may be hindering progress in muscle gain or fat loss. Moreover, assessing liver and kidney function through blood tests ensures the overall health and longevity of bodybuilders. Regular blood work is essential for identifying potential health risks and allowing for timely intervention to maintain a high quality of life. How can bodybuilders prepare for these tests? To prepare for bodybuilding blood work, it's important for bodybuilders to stay hydrated, avoid strenuous exercise or heavy lifting 48 hours before the test, follow any fasting requirements given by the healthcare provider, and inform them about any supplements or medications being taken. Why is regular bodybuilding blood work essential? Regular monitoring of crucial parameters is essential for bodybuilders. It helps ensure optimal performance and overall health. By tracking hormone levels, liver function, and kidney function, bodybuilders can make informed decisions about their training, nutrition, and supplementation strategies. Regular blood work also provides a baseline for comparison and allows assessment of the effectiveness of lifestyle choices on health and performance. How to Buy Affordable Bodybuilding Blood Work on DiscountedLabs.com To buy affordable bodybuilder blood work on DiscountedLabs.com, simply visit the website and create an account. Then, search for the specific bodybuilder blood work panel you need and add it to your cart. Proceed to checkout and apply any available discount codes before completing your purchase. Bodybuilder Panels Sold by DiscountedLabs.com Bodybuilder Blood Test Panel- Basic Bodybuilder Blood Test Panel- Beginner Bodybuilder Blood Test Panel- Comprehensive Conclusion Regular bodybuilding blood work is essential for maximizing performance and maintaining good health. It helps bodybuilders identify any imbalances or potential health risks caused by their training regimen and performance-enhancing agents. Understanding the importance of these tests and regularly monitoring key parameters such as testosterone levels, kidney function, liver enzymes, and lipid profiles can help bodybuilders optimize their muscle gain, fat loss, and overall quality of life. To ensure accurate results, it is important for bodybuilders to prepare for these tests by following specific guidelines. Regular monitoring of these parameters allows bodybuilders to make adjustments to their training and nutrition plans, minimizing potential risks and improving long-term outcomes. DiscountedLabs.com offers affordable bodybuilder blood work, making it easier for individuals to access these crucial tests. Take charge of your bodybuilding journey and prioritize your health and performance with regular blood work.        

A brief introduction to testosterone and its properties and benefits Testosterone is the most important male sex hormone responsible for correctly functioning multiple body processes. This anabolic steroid is directly involved in developing reproductive organs in men and developing secondary male sexual characteristics. Testosterone plays a vital role in the lives of women, too. Inadequate testosterone amounts can lead to numerous health issues, such as low bone density (and susceptibility to fractures), poor sex drive, and lack of concentration. Table of Contents A brief introduction to testosterone and its properties/benefits What is hypogonadism?   Serum testosterone tests (assays) Types of testosterone fractions in the blood Types of testosterone tests How is testosterone level measured? Dr. Wang's analysis of testosterone assays 4 Types Of Testosterone Tests You Can Buy Today Why should you test your testosterone levels? How to get a testosterone test? Normal testosterone levels in men are between 300 ng/dL and 1,000 ng/dL. Normal testosterone levels in women are usually between 15 ng/dL and 70 ng/dL. This number varies depending on various factors such as the moment of the day, mood, diet, exercise level, and more. However, certain men might have low testosterone levels (under 350 ng/dL) and experience symptoms such as fatigue, lack of sexual desire, and developing male breasts (gynecomastia). Testosterone replacement therapy might be helpful for men who have low testosterone blood levels. This treatment will help raise testosterone levels to average values. Inadequate testosterone amounts can also impair muscle development and slow one’s progress in the gym. Men usually have 40 times more testosterone than women, and keeping T levels in the normal range is essential to ensuring proper muscle growth. Declining testosterone levels in men over 45 are typical and often cause erectile dysfunction (ED). Androgen deficiency, or hypogonadism, affects roughly 40% of men aged 45 or older.  Two-thirds of these men present with symptoms. While some symptoms, like ED, indicate a deficiency, additional symptoms can be similar to those of other diseases, such as cardiovascular disease.  What is hypogonadism?   Male hypogonadism is a clinical syndrome that results from the failure of the testes to produce physiological levels of testosterone (androgen deficiency) and an average number of spermatozoa due to disruption of one or more groups of the hypothalamic-pituitary-testicular (HPT) axis. There are three types of hypogonadism: Primary-testicular dysfunction leads to low testosterone levels and high levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Secondary dysfunction of the HPT axis results in low testosterone, LH, and FSH levels. Who should be tested for low testosterone? Mixed—manifests a mixture of primary and secondary hypogonadism and can be observed in older men. Very small or shrinking testes. Inability to father children; low or zero sperm count. The more symptoms a patient has, the more likely he is to have low testosterone.    The production of androgens in excess is a defining feature of hyperandrogenism (high testosterone in women), and testosterone levels have an impact on it. The most common clinical manifestation of hyperandrogenism is hirsutism, or excessive hair growth in androgen-dependent body areas. Other clinical manifestations of hyperandrogenism include acne vulgaris, weight gain, menstrual irregularities, and, in some women, polycystic ovary syndrome (PCOS) and acanthosis nigricans. Measuring the testosterone level isn’t an easy task. Tests for free, bioavailable, and total testosterone are essential to help diagnose hypogonadism and rule out other conditions. For those who may be candidates for testosterone therapy and those already on treatment, testing can also help assess and monitor testosterone levels.   This hormone can be bound to specific proteins in the body, and measuring it becomes problematic when it’s outside the normal ranges. For example, it’s relatively easy to determine the exact testosterone level of a healthy man, but not that easy if he’s hypogonadal (has low T) and his testosterone levels are dangerously low. More sensitive tests are required to measure low T concentrations in men, women, and prepuberty children. Scientists and medical professionals have created some reliable testosterone-measuring methods. These are called testosterone assays.   Serum testosterone tests (assays) According to the dictionary, the word “assay” refers to testing a particular material, ore, or substance to find its composting ingredients. Serum testosterone assay refers to accurately measuring the testosterone levels in the body of a male or female. Accuracy is essential because it directly impacts the diagnosing a particular disease or health complication. Endocrinology is the discipline responsible for measuring hormone levels in the body. It encompasses a wide variety of assays that help the clinician confirm a diagnosis for a patient. For example, testosterone assays are used to determine whether a male patient has hypogonadism. Hypogonadism consists of reduced gonad activity. Men diagnosed with hypogonadism usually have low testosterone levels and experience different symptoms, such as low sex drive and gynecomastia (man boobs). Testosterone assays are also used to determine if confident boys have delayed puberty onset and to diagnose androgen deficiency. When circulating testosterone levels are very low, the sensitivity of some assays is diminished. That’s why picking the suitable testosterone assay is necessary to determine circulating T levels accurately.   Types of testosterone fractions in the blood As shown in the figure below, about 2 percent of the testosterone in the body is active.  This “free testosterone” is not attached to binding proteins that would prevent it from interacting with its receptor. About 40 percent of the body’s testosterone is attached to albumin. This is a protein that can release the hormone as the need for it arises in the body. Free testosterone and testosterone bound to albumin are “bioavailable testosterone.” In a healthy young male, about 60 percent of his testosterone is attached to sex hormone-binding globulin (SHBG). Hormones bound to SHBG can’t be used by the body and lose their anabolic effect.  As males grow older or if an illness is present, SHBG sweeps up more and more testosterone, lowering free testosterone and its benefits. Total testosterone is the sum of bioavailable testosterone and testosterone bound to SHBG. Measuring the total testosterone in the blood may not provide the whole picture and let you know how much “active” or usable testosterone you have. Types of testosterone tests Measuring the testosterone levels in one’s body is not that easy. One way to do that is by using Isotope dilution mass spectrometry. This assay measures total testosterone levels. Laboratories also use direct chemiluminescent immunoassays. However, these assays are less accurate when testosterone concentrations are too low. Liquid chromatography-tandem MS (mass spectrometry) and gas chromatography-MS are also used for more accurate results, mainly when testosterone levels are at the low and high extremes. Measuring free testosterone is done after it has been separated from the protein-bound forms. This can be done using equilibrium dialysis or ultracentrifugation. Equilibrium dialysis is the most common method, and it involves introducing testosterone isotopes into a patient sample. The free testosterone concentration is estimated based on the distribution of isotopes in the dialysis membrane. The bioavailable testosterone can be measured using ammonium sulfate, which influences the testosterone bound to SHBG. Assessing testosterone levels began approximately 30 years ago. Tests were done on small blood samples, but their accuracy could have improved. Current testosterone assays are more sensitive, require a smaller serum sample, and are more affordable. They can be done using nonradioactive methods in reference labs.   How is testosterone level measured? Up to 98% of the testosterone found in the bloodstream is bound to proteins such as albumin and SHBG. Just about 2% is free. Albumin-bound testosterone and free testosterone are known as bioavailable, and tissues can easily use them for androgen action. On the other hand, total testosterone can be measured using nonradioactive immunoassay and chemiluminescent detection. These methods offer accurate results if the male patient has testosterone levels in the normal range, such as 300-1000 ng/dL. However, these assays recorded low testosterone limits of approximately 132 ng/dL, which is not customary in healthy men. Clinicians have wondered why this happens and how they can improve the accuracy of testosterone assays when T concentrations are deficient. Regarding total testosterone assays, the gold standard is a steroid-free serum interacting with gravimetrically-determined amounts of testosterone. Independent measuring methods, such as liquid or gas chromatography with mass spectrometry, are also used. Susceptible tests are necessary for women to determine total and free testosterone levels because women have much lower amounts of testosterone in the bloodstream.   Dr. Wang's analysis of testosterone assays In a paper published in 2004, Dr. Wang and her colleagues compared multiple testosterone immunoassays (both manual and automated ones) with chromatography-tandem mass spectrometry. The results were very accurate for the latter option, and the test was performed on serum samples from patients with different testosterone levels (ranging from under 150 ng/dL to 1,500 ng/dL). This means that most of the automated and manual assays were accurate compared to LC-MSMS, but some tests provided inaccurate results. The authors concluded that most manual and automatic testosterone immunoassays are ideal for differentiating eugonadal men from hypogonadal men. Still, they weren't accurate for women or children who haven't reached puberty yet. It’s essential to notice that these automated and manual testosterone immunoassays are compared with gold standards of adult male reference ranges. These ranges are set by individual laboratories and are usually monitored by the College of American Pathologists. That’s why you’ll find several testosterone tests on the market. Getting the right one is essential to obtain the most accurate results.   4 Types Of Testosterone Tests You Can Buy Today There are four different testosterone assays you can choose from to determine the amount of testosterone in your bloodstream accurately.   #1 - TESTOSTERONE Total and Free (Regular) This test is ideal for people with testosterone levels in the normal range. It measures total and free testosterone using direct analog/radioimmunoassay (for free T) and electrochemiluminescence immunoassay (for real T). On the other hand, if you know you have deficient testosterone levels (hypogonadism and testosterone levels below 150 ng/dL) or very high testosterone levels (you are a bodybuilder with T levels over 1500 ng/dL). You might want to use the LC/MS test because it’s more accurate. If your testosterone levels are very high, the test will show above 1500 ng/dL, not the exact number (such as 1,700 or 1,800).   #2 - Testosterone Free and Weakly Bound (Bioavailable Testosterone) Bioavailable testosterone can be used for steroid-receptor interaction. This test measures the amount of free and weakly bound testosterone in the bloodstream. The test doesn’t look at the testosterone bound to SHBG because this type is biologically inactive as it has a high binding affinity. On the other hand, weakly bound testosterone is usually derived from albumin and has a low affinity, which means that it can quickly dissociate and become available for interaction.   #3 - Testosterone, Free, Bioavailable, and Total, LC/MS (No Upper Limit) This test has no upper limit for either type of testosterone, such as free, total, or bioavailable. It uses more complex measuring assays such as liquid chromatography-tandem mass spectrometry to determine testosterone levels accurately. However, this test is more suitable for bodybuilders, who are known to have very high testosterone levels. If you are not into bodybuilding or think you have below-normal testosterone levels, this test is not ideal for you. Other tests are more economical and can be used to determine your testosterone levels more accurately. If you are on testosterone replacement therapy, you might want to choose a test that has no upper limit on total testosterone and up to 50 ng/dL limit on free testosterone. An even more affordable test for people on testosterone replacement therapy has an upper limit of 1,500 ng/dL on total testosterone and a 50 ng/dL limit on free testosterone.   #4 - Testosterone, Total, LC/MS (No Upper Limit) This test measures only total testosterone by liquid chromatography or mass spectrometry. This test is ideal if your testosterone levels are deficient (both men and women). It is also suitable for high testosterone levels due to TRT or bodybuilding.  The test is the most accurate for testosterone concentrations under 150 ng/dL or above 1500 ng/dL for total testosterone.     Why should you test your testosterone levels? Measuring testosterone levels has become increasingly popular nowadays, thanks to direct-to-consumer labs that are affordable and easy to use. Males and females can buy one of the tests described above and determine the actual amounts of testosterone in their bloodstream. But why is this a good idea? First, if you have common testosterone deficiency symptoms such as fatigue or low sex drive, then measuring your testosterone levels is highly recommended. This will help you decide whether a lack of testosterone is the problem and whether you should try testosterone replacement therapy. Testosterone tests give you a broader insight into your hormonal health. Secondly, if you’re on testosterone replacement therapy already, the test results might provide good feedback on your progress. The clinicians who conduct these tests can give you valuable adviceLong-Term, such as how often to take testosterone gels or injections, whether you should reduce or increase the dosage, etc. If you’re a bodybuilder, keeping your testosterone levels in check also helps you monitor your progress. After all, testosterone is vital for muscle development, and if you have sufficient amounts of it, you’ll ensure muscle growth in the long run. Testosterone is essential for women too. This hormone is linked to mental alertness, good mood, and increased sex drive. Testosterone deficiency in women can also lead to low productivity at work and poor physical performance in the gym. Numerous advancements in the medical field coupled with improved testing devices make measuring testosterone levels a more affordable and accurate process.   How to get a testosterone test? Visit Discounted Labs, pick your favorite testosterone blood tests, and you’ll be able to get your results in a few business days. You can also order other blood tests to check your glucose levels, cholesterol, triglycerides, blood count, and more!  

  Since abnormally high hematocrit values can pose serious health problems, this article will analyze the correlation between testosterone therapy and high hematocrit. TRT, sleep apnea and smoking are contributing factors that can cause high hematocrit, which can increase cardiovascular risks if not properly managed. This article explains the basics of how to manage high hematocrit while using testosterone. High hematocrit: Why it is important? The red cells are some of the most important components of a person’s blood. The term hematocrit refers to the percentage of red blood cells in a human’s body. For women, normal hematocrit values should be around 42% and for men, it should be around 47%. A complete blood count test will show the number of red blood cells in the blood as well as the hemoglobin values, white blood cells, and platelets. When the hematocrit is too high, meaning that there are too many red blood cells, this condition is known as polycythemia. When the hematocrit values are too low, this condition is known as anemia. Abnormal hematocrit values can put one’s life in danger if not treated promptly. Since abnormally high hematocrit values can pose serious health problems, this article will analyze the correlation between red blood cell count and various medical conditions such as obstructive sleep apnea syndrome, erythrocytosis caused by testosterone replacement therapy and why people should be careful when donating blood more than once a year. It is important to also know the red cell distribution width (RDW), which is a laboratory measuring system that analyzes the size of red blood cells. Doctors frequently examine the RDW to determine the causes of anemia and to gain more insights about the severity of different cardiovascular diseases.  Platelets are cytoplasmic fragments that quickly react when bleeding is detected in the body. They help in the coagulation process to prevent infection and initiate the healing process. The mean platelet volume (MPV) is a way of measuring the size of the platelets. Both these terms, RDW and MPV, will be used to examine the link between obstructive sleep apnea syndrome and high hematocrit values. Obstructive sleep apnea syndrome (OSAS), red blood cells and high hematocrit values OSAS is a sleep disorder that is characterized by a collapse of the upper airway while sleeping. This leads to a low quality sleep, choking sensations, and even hypoxia (low oxygen saturation). A comprehensive study performed between January 2011 and June 2014 shows that high RDW might be a reliable marker when it comes to the severity of OSAS. Hematocrit TRT Study Material and Methods 264 patients were admitted to the sleep unit to undergo a polysomnographic evaluation and were subsequently diagnosed with OSAS. 116 of these patients met the criteria of the study and agreed to participate. These patients reported frequent unpleasant symptoms such as daytime sleepiness, severe snoring at nighttime, etc. The exclusion criteria left out patients who had various types of medical conditions that might have interfered with the results of the study. For example, patients who had known cardiovascular diseases, were smokers, had diabetes mellitus, lung disease or hypertension were not included in the study. The 116 patients who participated in the study were divided into several groups, depending on the apnea-hypopnea index (AHI) which basically indicates the severity of the sleep apnea. There were 3 groups – mild (AHI between 5 and 15), moderate (AHI between 15 and 30) and severe (AHI higher than 30). There was also a control group of 62 individuals who had an apnea-hypopnea index of less than 5. The study was performed using polysomnographic methods. Researchers have attached suprasternal microphones to assess the airflow of the patients during sleep. Blood samples were also drawn using a 21-gauge needle syringe after a fasting period of 8 hours. The apnea was defined as a stop of airflow for 10 seconds or more during sleep. Hypopnea was defined as a reduction of airflow between 30% and 50% as well as a decrease in capillary oxygen saturation. Sleep Apnea and Testosterone- Study Results At the end of the study, researchers have reached the conclusion that patients with severe OSAS have a higher RDW, a higher platelet count and MPV. In addition, the hematocrit and RDW are positively correlated with apnea-hypopnea index. This means that the complete blood count is very important for patients diagnosed with OSAS. It is well known that patients with OSAS experience a state of systemic inflammation due to a variety of causes. This state of inflammation can lead to a higher secretion of pro-inflammatory cytokines such as interleukin-6, which in turn can create erythrocyte deformability and a higher level of RDW. Other studies have shown that high RDW levels are also associated with a higher-sensitivity CRP level which is a known marker of inflammation. One of the most important reasons which make this study unique and highly accurate is the simple fact that patients who suffered from serious health conditions such as coronary artery disease, diabetes mellitus, and hypertension didn’t take part in the study. It is a well-known fact that these illnesses can lead to a higher RDW level which could have compromised the results of the study. Patients who suffer from OSAS also experience hypercoagulability which is caused by high blood viscosity. Hematocrit, erythrocyte behavior, and other factors all affect blood viscosity, which is defined as the resistance of blood to external forces. It has been established that hematocrit plays an important role in the coagulability of blood and can lead to increased blood clotting. When there is an increased blood clotting in the body, the natural flow of blood can be negatively affected and multiple cardiovascular issues can appear. Researchers believe that the hypoxemia experienced by patients with OSAS is caused by a release of inflammatory factors that negatively affect the blood and can lead to hypercoagulability. It has also been found out that the total platelet count in patients with OSAS was higher in comparison with the patients in the control group or those in the mild group. This is real evidence of the correlation between platelet activation and cardiovascular diseases in patients suffering from OSAS. This comprehensive study has shown evidence that RDW, MPV, and platelet count are increased in patients diagnosed with OSAS. The RDW index is also positively correlated with oxygen desaturation index and AHI. Since RDW is included in a standard blood count measurement, it can become an inexpensive and simple tool to diagnose the severity of the OSAS in patients of all ages. As a result, patients who suffer from a severe OSAS can be given priority when it comes to treatment, improving their chances of recovery.   Understanding the occurrence of high red blood cells and hematocrit on testosterone replacement therapy   Erythrocytosis is a medical condition that appears when the body is making too many red blood cells. RBCs are responsible for transporting oxygen to organs and tissues. When there are too many, the blood can become too thick and cause cardiovascular complications. There are 2 types of erythrocytosis – primary and secondary. Primary erythrocytosis is usually caused by bone marrow problems. RBCs are made in the bone marrow and something might trigger an increase in their production. Certain diseases or medications, such as testosterone replacement therapy, can cause secondary erythrocytosis. TRT is the go-to treatment for people who suffer from hypogonadism – aka androgen deficiency. This type of treatment is increasingly popular, especially among people over 40 years of age. It can increase libido, help to maintain muscle mass, improve mood and general wellbeing. However, one of the side effects of TRT is a simple fact that it can cause erythrocytosis. An increase in hemoglobin (Hb) and hematocrit (Hct) is indicative of this medical condition. When the Hb is higher than 18.5 g/dL and the Hct is higher than 52% in men, the patient suffers from erythrocytosis. Since the RBCs count is too high in people with erythrocytosis, the blood viscosity also increases, which can lead to various potentially life-threatening medical issues such as venous thromboembolism. This essentially means that small blood clots separate from their original source and travel through veins and capillaries, causing blockages that result in stroke, myocardial infarction, or other complications. CHECK YOUR HEMATOCRIT TEST WITH A CBC PANEL Testosterone replacement therapy formulations   Testosterone replacement therapy is recommended for men who have testosterone levels lower than 300 ng/dL. It is commonly accepted that T levels decrease by approximately 1% per year after 35 years of age. TRT has been shown to improve the mood of the patients, correct insulin resistance problems, and help increase bone density and muscle mass, among other positive benefits. Getting testosterone into the body can be done in various ways. There are injections, gels, buccal patches, pellets, and others. Some formulations show results much quicker (injections, for example) and each one of them has different effects on patients, depending on the dosage, administration option, etc. TRT-induced high red blood cell volume ( high hematocrit ) When the testosterone levels increase in the body, the hemoglobin and hematocrit levels also increase. Studies have shown that people who undergo TRT have higher blood viscosity and platelet adhesiveness, which can lead to thromboembolic risks. Although there are not many studies that link TRT-induced erythrocytosis (high red blood cells) with thromboembolism, one small research performed by Krauss et al on a group of 15 men can lead to interesting conclusions. The 15 men received short-acting IM TE (testosterone injection) every 21 days and had their bloodwork and testosterone levels monitored. The researchers discovered a correlation between transient ischemic attacks and men who had a mean Hct levels higher than 48%. Although the study was performed on a small group of men, it is an important research finding because throws a spotlight on the potential side effects of TRT. Additionally, the FDA also forces companies that make testosterone products to add a warning on the label stating “possible increased risk of heart attacks and strokes in patients taking testosterone”. High hematocrit: The effects of different testosterone products Researchers have discovered that various testosterone formulations have different effects when it comes to the occurrence of erythrocytosis in patients who undergo TRT. For example, short-acting injectables such as IM TC and IM TE render an incidence of erythrocytosis higher than 40%. The other formulations have a much lower incidence and are considered safer, although testosterone is absorbed much slower into the body. Men who are prescribed and use transdermal gels such as AndroGel 1.62% have an approximately 13% chance of developing erythrocytosis, according to some studies. These types of gels can have a dose of testosterone of 20–100 mg and can be applied to the shoulder area or directly on the skin. Similarly, crystalline pellets that are implanted under the skin have a T formulation of 75mg per pellet and can lead to a 35% chance of developing erythrocytosis in the long run. Studies define erythrocytosis as a hematocrit level higher than 52%. Researchers have found a possible link between high hematocrit levels and high hemoglobin levels in people who are on testosterone replacement therapy. However, more in-depth studies are needed to fully understand the molecular mechanisms that cause erythrocytosis to happen during TRT. Furthermore, some studies show that there is also a higher risk for patients who benefit from TRT to develop CV complications as a result of increased blood viscosity. It's important to also develop other treatment options for hypogonadal men, such as aromatase inhibitors, human chorionic gonadotropin, and others. Lastly, when TRT is absolutely necessary, patients might take into consideration safer testosterone products, such as undecanoates, which can be taken orally or as transdermal gels. Understanding why blood donations shouldn’t be done too frequently It is estimated that approximately 70% of the blood supply in the United States comes from repeat donors. Although donating blood is a commendable act, people should be careful when donating several times a year because they can develop iron deficiency. A plethora of men decides to donate blood to also decrease hematocrit levels. A study conducted on 235 men concluded that frequent blood donors can develop iron deficiency The group of 235 men was separated into 3 categories: – control group with no donations, group 2 with 2 donations per year and group 3 with 3 donations per year. The age of the donors was between 17 and 65 years and their hemoglobin values were higher than 12.5 g/dl. Donors who took iron supplements before were excluded from this study to avoid interfering with the results. The researchers looked at a couple of important values, such as hemoglobin and ferritin levels. Ferritin is a type of intracellular protein responsible for transporting and releasing iron throughout the body. Iron deficiency was defined as serum hemoglobin levels below 13 g/dl and serum ferritin levels below 15 μg/l. No participant in the study has donated blood in the previous 8 weeks. Researchers have found out that the patients in the case groups (2 and 3) had a decreased level of hemoglobin and ferritin in comparison with the patients in the control group. More specifically, men in group 3 had ferritin mean levels of 26 and a hemoglobin level of 13.8, those in group 2 had ferritin mean levels of 56 and hemoglobin levels of 15.4 while the control group had ferritin mean levels of 108 and hemoglobin levels of 15.9. Caution about frequent blood donations: The study presented evidence that donating blood more than once or twice per year can significantly deplete iron stores and can lead to anemia. Moreover, the medical industry relies on donations of a healthy supply of blood rich in iron, so certain donors (especially those who donate frequently) might not be eligible for repeat donations. Likewise, measuring the hemoglobin level only might not be a reliable indicator of a person being suitable for blood donation or not. The ferritin levels should also be taken into account to prevent anemia in various donors. Is supplementing with iron a solution for low iron/ ferritin caused by frequent blood donations? This is a good question, but the answer might not be that simple. It is a well-known fact that supplementing with iron should be done carefully since too much iron in the bloodstream can cause damage to organs and tissues. Additionally, those patients who have family members with cancer might not be eligible for iron supplementation. Speaking with a doctor before taking iron supplements is the best thing to do.   Buy a low cost testosterone test    References: Ohlander et al. Sex Med Rev 2018; 6:77-85 Yousef and Alkhiary, J Sleep Disord Ther 2015, 4:2

Did you know that testosterone deficiency has a prevalence of up to 40% in adult males in the United States? A man is deficient in testosterone when his T levels fall below 300 ng/dL of blood. Although this is slightly worrisome news, there are multiple testosterone replacement options you can take advantage of these days. This article focuses on some of the most important testosterone products in 2023. Keep reading to learn key facts, statistics, price ranges, and optimal dosages related to your favorite testosterone products. Top Testosterone Replacement Therapy Options You Have in 2023 Fortunately, there are many ways you can get more testosterone into your system. There are patches, pellets, gels, injections, and even oral capsules that you can take once or twice a day. If you don't really fancy having to inject testosterone once a week, you can take capsules orally and reap all the benefits of testosterone replacement therapy. The following is a quick list of testosterone replacement products you can take advantage of to increase blood T levels. Administration of T products should only be done according to the strict guidance of your TRT doctor. FDA-Approved Testosterone Brands Androderm: Androderm is a transdermal testosterone patch that delivers testosterone through the skin. It is applied daily to maintain stable testosterone levels in men with low testosterone due to certain medical conditions[1]. This option is no longer used by most doctors since its efficacy was not good and it caused skin irritation. AndroGel: AndroGel is a topical testosterone gel that is applied directly to the skin, typically on the upper arms, shoulders, or abdomen. It is designed for daily use to help maintain consistent testosterone levels for men with low testosterone[1]. It comes in two concentrations. Fortesta: Fortesta is another topical testosterone gel applied to the skin, usually on the front and inner thighs. It is used for testosterone replacement therapy in males with low testosterone levels[2]. Testim: Testim is a testosterone gel applied daily to the skin, typically on the upper arms and shoulders, to help maintain consistent testosterone levels in men with low testosterone due to certain medical conditions[1]. Depo-Testosterone: Depo-Testosterone is an injectable form of testosterone prescribed for men with low testosterone levels. It is administered by a healthcare professional at regular intervals, typically every two to four weeks[2]. Testopel is a subcutaneous testosterone pellet that a medical professional implants under the skin. The pellets release testosterone over an extended period, typically three to six months[2]. Aveed: Aveed is an injectable testosterone undecanoate solution designed for long-acting testosterone replacement therapy. It is administered by a healthcare professional at regular intervals, typically every 10 weeks after an initial loading phase[2]. Natesto: Natesto is a testosterone nasal gel that is applied inside the nostrils for testosterone replacement therapy. It is used to treat men with low testosterone levels due to certain medical conditions[2]. Vogelxo: Vogelxo is a topical testosterone gel applied daily to the skin, usually on the upper arms, shoulders, or abdomen. It is used for testosterone replacement therapy in males with low testosterone levels[2]. Xyosted: Xyosted is a subcutaneous testosterone enanthate autoinjector for weekly self-administration. It is prescribed for men with low testosterone levels due to certain medical conditions[2]. Jatenzo: Jatenzo is an oral testosterone undecanoate capsule that the FDA has approved to treat certain types of hypogonadism in men. It is taken orally to help maintain stable testosterone levels in men with low testosterone [2] Testosterone Treatment Prices and Dosing Androgel 1% Price for a 30-day supply (in USD): 55-85 for the generic pump, 90-190 for 50 mg generic packets; also, around 650 USD for Brand 50 mg packets Delivery mode: pump and/or packet Dosage: 25 mg/2.5 g or 50mg/5g Where to apply shoulders, upper arms or on the abdomen Starting dosage: 50 mg daily dose early in the morning When to measure: in the morning before applying the gel Androgel 1.62% Price for a 30-day supply (in USD): 40-140 for the generic pump, 620-640 for Brand pump Delivery mode: pump and/or packet Dosage: 20.25 mg or 40.5 mg Where to apply shoulders or upper arms Starting dosage: 40.5 mg daily dose early in the morning When to measure in the morning before applying the gel Testim 1% Price for a 30-day supply (in USD): around 600-610 for packets Delivery mode: pump Dosage: 20.25 mg per actuation Where to apply shoulders or upper arms Starting dosage: one pump on each shoulder for a total of 40.5 mg early in the morning, it can also be applied on inner thighs When to measure: in the morning before applying the gel Fortesta 2% Delivery mode: pump Dosage: 50 mg or 100 mg Where to apply shoulders or upper arms Starting dosage: two pumps daily in the morning on each thigh When to measure: 2 hours after applying a dose Vogelxo Price for a 30-day supply (in USD): 100-350 for 1% pump, 120-350 for generic packets Delivery mode: shoulders or upper arms Dosage: 50 mg from 4 actuations of 12.5 mg testosterone Where to apply shoulders or upper arms Starting dosage: 50 mg daily in the morning When to measure before applying a dose Androderm Delivery mode: patch applied at night after 10 PM Dosage: 2 mg per day, 2.5 mg per day, 4 mg per day or 5 mg per day Where to apply: abdomen, upper arms, thighs, back Starting dosage: 4 mg per day When to measure: 12 hours after skin application Natesto Price for a 30-day supply (in USD): 195-300 for 5.5 mg/actuation Delivery mode: intranasal pump Dosage: 5.5 mg per pump actuation Where to apply intranasal Starting dosage: 11 mg (2 actuations) 3 times per day at an interval of 6-8 hours When to measure: 2 hours after nasal application Jatenzo Price for a 30-day supply (in USD): around 950 for 237 mg BID pill Delivery mode: oral capsule Dosage: 158 mg, 198 mg, or 237 mg Where to apply oral Starting dosage: 237 mg capsule twice a day (one in the morning, one in the evening) When to measure: 6 hours after the morning dose Testopel Delivery mode: pellet Dosage: 75 mg per pellet Where to apply can be inserted under the skin, in the fat of the buttocks, thigh or lower abdominal wall Starting dosage: 150-450 mg every 3 to 6 months When to measure: at the end of the dosing interval Aveed Delivery mode: injectable solution Dosage: 100 mg/10 ml vial, 200 mg/1-10 ml vial or 750 mg/3 ml vial Where to apply: intramuscular in the glute or thigh muscles Starting dosage: 750 mg (3 ml) in the beginning, then after 4 weeks then after every 10 weeks; 75-100 mg/week also or 150-200 mg every 2 weeks When to measure: injections are administered every 10 weeks and T measurement should be done somewhere in between injections (after 5 weeks or so since the last one) Xyosted Price for a 30-day supply (in USD): 455-575 for 50 mg, 75 mg and 100 mg injections Delivery mode: the solution is placed in the autoinjector Dosage: 50 mg, 75 mg or 100 mg respectively Where to apply: in the abdominal region under the skin Starting dosage: 75 mg applied under the skin once a week When to measure T levels: trough concentrations are measured 7 days after the most recent dose and only after 6 weeks since the beginning of treatment. These are just a few popular testosterone replacement products available in the US. Keep in mind that you can also procure testosterone enanthate in 5 ml (1000mgs) vials from certain pharmacies. This option usually costs less than $30 for a 30-day supply and the testosterone can be injected by each patient without requiring a doctor's visit. Similarly, TRT patients can also choose to use generic testosterone cypionate or enanthate as 400 mg to 800 mg per month that can be injected into muscle (deep IM or shallow IM) or under belly fat (subcutaneous) . The price for a 30-day supply starts at around $30 and it can go up to $85 . (Source: GoodRx). Other affordable sources of testosterone treatments can be purchased from compounding pharmacies like Empower in Houston. Check Out How AUA and ES Guidelines Differ on Testosterone Ranges AUA stands for American Urology Association and ES stands for Endocrine Society. They provide detailed insights and standards on how to interpret hormone levels and blood test results. In some cases, these committees can give different interpretations when it comes to testosterone levels. AUA Guidelines: What is a Normal Testosterone Range and Follow Up? According to the American Urology Association (AUA), you should measure your testosterone levels in the morning in a fasted state to get accurate results. The normal range is between 450 ng/dL and 600 ng/dL of blood. If your levels fall below 300 ng/dL of blood, you are considered to be deficient in testosterone. If you start testosterone replacement therapy, your first evaluation should be between 2 and 4 weeks after beginning treatment. You will also have to attend follow-up visits 6 to 12 months after starting TRT. ES Guidelines: What is a Normal Testosterone Range and Follow Up? On the other hand, the Endocrine Society (ES) gives slightly different reference ranges. For example, the normal testosterone range is between 264 ng/dL and 916 ng/dL of blood. The best moment to test your T levels is early in the morning in a fasted state. Testosterone deficiency is confirmed if your T levels fall below 264 ng/dL of blood.  TRT follow up visits should be done after 2-3 months and after 6 to 12 months from the start of your testosterone replacement protocol. How to Get Your Own Affordable Testosterone Test Remember that now it's easier than ever to check your testosterone levels and see if you are a suitable candidate for testosterone replacement therapy. If your T levels fall below 350 ng/dL and have low testosterone symptoms then you should talk with a TRT doctor and see what testosterone replacement options you have. Check your testosterone levels quickly and confidentially by ordering a total and free testosterone test from DiscountedLabs today. Key Terminology and Facts About Testosterone It's important to also have some basic understanding of how testosterone works in the body, so you can make better decisions when talking with your TRT doctor. For instance, the Leydig cells in your testicles produce more than 95% of your testosterone. Testosterone daily production ranges from 3 mg to 11 mg and it peaks early in the morning. Healthy adult males have the highest concentration of testosterone early in the morning and it gradually drops throughout the day. That's why the best time to measure your T levels is early in the morning to get accurate results. Natural Testosterone Short half-life - your testosterone has a half-life between 10 and 100 minutes. It peaks once every 3 hours as the luteinizing hormone stimulates the Leydig cells to produce more testosterone. With the passing of time, these cells become less sensitive to LH and they produce increasingly low T levels. It's estimated that males lose about 1% of their testosterone production every year after the age of 30. 2 percent is free; about 2% of your total testosterone level is free. This means that it circulates freely through the bloodstream and it can bind to other organs or tissues. 70% of your testosterone is bound to sex hormone-binding globulin and nearly 30% is bound to albumin. Testosterone metabolism - fractions of your testosterone are converted into other hormones and substances. For example, from 5% to 8% of your testosterone is converted into dihydrotestosterone (DHT). This hormone is responsible for prostate maturation and the growth of the body, as well as facial and pubic hair. About 0.3%–0.5% of your testosterone is also converted into estradiol by the aromatase enzyme. Some of the main roles of estradiol in men are involved with libido and bone health. Trough concentration - this refers to the lowest  concentration of a drug in the bloodstream immediately before injecting or administering another dose. It's highly recommended to measure your testosterone levels at trough concentration because this will produce the most accurate results. Based on these results, TRT doctors can make more accurate adjustments to your protocol. Find Out More About Testosterone Products! This is just a brief overview of some of the most popular testosterone products in the US, but there's plenty more high-quality information out there. Visit Excelmale.com and learn everything you need to know about testosterone, TRT, how to interpret your blood test data, and how to tweak your protocol for optimal results. Also, you can download the Testosterone Replacement Options paper from this link.   References: [1] "FDA-approved testosterone formulations include the topical gel, transdermal patch, buccal system (applied to upper gum or inner cheek), and injection. The manufacturers of two prescription..." URL: https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/testosterone-information [2] "by Drugs.com Brand names of testosterone include Androderm, AndroGel, Fortesta, Testim, Depo-Testosterone, Testopel, Aveed, Natesto, Vogelxo, Xyosted, Jatenzo, Tlando, and Kyzatrex. Testosterone is an androgen indicated for testosterone replacement therapy in males." URL: https://www.drugs.com/medical-answers/brands-testosterone-3510863/   Recommended Sources: Testosterone Replacement Therapy Options | Excel Male TRT Forum Testosterone Replacement Products in the U.S.: Video Review by Nelson Vergel - ExcelMale Testosterone Test Near Me: Your Complete Guide Testosterone levels show steady decrease among young US men        

  In a recent study, researchers explored whether consuming glucose (a type of sugar) affects testosterone levels in men who are receiving testosterone therapy, which is a common treatment for men with low testosterone levels. Men's testosterone levels can vary depending on a variety of factors, including their diet. Testosterone is a crucial hormone that affects many bodily processes. Is Fasting for Testosterone Test Required in Men on TRT? Study Overview and Objectives According to the findings of a recent study, scientists looked at the potential connection between male patients undergoing testosterone therapy—a typical treatment for low testosterone levels—and their intake of glucose, a type of sugar, and their testosterone levels. The aim of the research was to determine whether consuming glucose had an effect on testosterone levels. A man's diet is one of several factors that could influence his testosterone levels. A variety of other factors may also have an impact on a man's testosterone levels. Testosterone is involved in a large number of bodily processes. It is an essential hormone. Methodology and Participant Demographics An explanation of the methodology and pertinent information: Men with low testosterone and type 2 diabetes—a condition in which the body struggles to regulate blood sugar levels—made up the bulk of participants. In this study that examined the effects of glucose, fourteen individuals drank a glucose drink with 75 grams of sugar. The following two hours were spent doing the experiment and measuring the subjects' testosterone levels. It was done once, before the men started testosterone replacement therapy (TRT), and once more after the men had TRT injections for 23 weeks. The first round of this test was done before the guys started taking testosterone treatment. Initial Findings An Overview of the Most Significant Results: Before beginning testosterone therapy, the men reported that their testosterone levels had dramatically dropped after a carbohydrate meal; nevertheless, these levels had returned to normal in less than two hours. This took place before the testosterone treatment began. This was prior to the men beginning to raise their testosterone levels with TRT. It's an intriguing phenomenon because during 23 weeks of testosterone therapy, the body's levels of testosterone were unaffected by glucose ingestion. Participant Characteristics Age and Average Body Mass Index: The average body mass index (BMI), which calculates body fat based on height and weight, for the individuals was 38 kg/m2, indicating obesity. The average age of the individuals was 53. Conclusion and Implications  The results of the study show that men on testosterone therapy do not temporarily lower their testosterone levels when they consume glucose in the same way as men not receiving treatment. This finding is important for the creation of medical guidelines because it suggests that, although testosterone levels should be measured during fasting in order to diagnose low testosterone in men not on TRT, these levels may not need to be tracked in the same manner once testosterone therapy has begun. This is an important finding since it suggests that the baseline testosterone levels should be evaluated while fasting, but the follow up testosterone blood tests do not require fasting once men are on TRT. Clinical Recommendations Specific Guidance on Implementing Clinical Practice: The findings suggest that endocrinology societies should update their guidelines to include the possibility that fasting testosterone levels may not be necessary for monitoring the effectiveness of testosterone therapy in men who are already receiving treatment, even though they are necessary for diagnosing low testosterone. There would be an advantage to the field from this advancement. Study Significance This paper offers important insights into how dietary glucose impacts hormone levels in males with diabetes getting testosterone therapy, which helps to clarify the complexity of treating endocrine illnesses. The factors that specifically influence hormone levels are the subject of the investigation.   Reference: 1.Dhindsa S, Ghanim H, McPhaul MJ, Ghoshal AK, Dandona P. Glucose Ingestion does not lower Testosterone concentrations in men on Testosterone Therapy. Journal of Investigative Medicine. 2024;0(ja). doi:10.1177/10815589241252510

Except for estradiol, no hormone is more misunderstood than dihydrotestosterone, or DHT. Many men fear DHT, going out of their way to use a DHT blocker for their medical condition. However, DHT is a critical hormone, one that men need for sexual and prostate health, cognitive function, skeletal strength, and many other reasons. Like everything in life, there are downsides to DHT, but the upside of healthy DHT levels far outweighs the challenges it can present. It is crucial to choose a DHT blocker that has support from scientific research in order to ensure both safety and efficacy when considering its use for hair thickness and general health care. In the intricate world of hormones and their impact on men's health, Dihydrotestosterone (DHT) often emerges as a topic of considerable debate and intrigue. This potent androgen, frequently overshadowed by its more famous counterpart testosterone, plays a pivotal role in numerous physiological processes yet is often misunderstood or feared due to its association with certain medical conditions. Our journey in this article is to demystify DHT, unraveling its complexities to reveal not just the concerns it raises but, more importantly, the indispensable benefits it offers for male health. From sexual wellness to cognitive abilities and skeletal integrity, DHT's influence is far-reaching, making it essential to understand and appreciate its role in the broader context of hormonal balance and overall health. DHT – FRIEND OR ENEMY? Except for estradiol, no hormone is more misunderstood than dihydrotestosterone, or DHT. Many men fear DHT, going out of their way to lower it and frustrate its biological activity. However, DHT is a critical hormone, one that men need for sexual and prostate growth, cognitive function, skeletal strength, and many other reasons, such as hormonal health conditions. Like everything in life, DHT has downsides, but the upside of healthy DHT levels far outweighs the challenges it can present. DHT, the main hormone involved in male-pattern hair loss, can attach to receptors in your scalp and damage your hair follicles, leading to a receding hairline, hair thinning, and even severe hair loss. DHT – Where it Comes From The principal hormone produced in men is, of course, testosterone. When testosterone is produced by the testicles (or injected or absorbed by a man on testosterone replacement), an enzyme, 5-alpha reductase(5-AR), sets to work, converting a portion of that testosterone to DHT, which is the conversion of testosterone into the androgen hormone dihydrotestosterone (DHT). This conversion prevents some testosterone from reaching the androgen receptors in the brain, genitals, skin, and other tissues. Initially, that may sound like the body is deprived of a needed hormone, testosterone. However, for the most part, this conversion is actually in a man’s best interest. Though estimates vary, DHT binds much more efficiently to androgen receptors; DHT is 300 to 500 percent more efficient at reaching and binding to the receptors and is far more potent than testosterone. If tissues were deprived of DHT, 5-AR hadn’t done its job; there would be dramatic physiological changes. While it is true that testosterone remains the primary, active androgen in muscle and muscle development, DHT is still critical for testosterone's full performance-enhancing effects. Specifically, the impact of DHT on the central nervous system increases neurological efficiency and strength. The production of body hair DHT comes from testosterone, with the help of the enzyme 5-alpha reductase (5-AR). The production of DHT is a natural process that occurs when testosterone is converted into the androgen hormone dihydrotestosterone (DHT) with the help of the enzyme 5-alpha reductase (5-AR). DHT – Positive Effects  To understand DHT’s androgenic properties, consider the following. Male Development – Physical and sexual development in the human male is DHT-dependent. DHT is responsible for the growth and development of the penis, the prostate, and the testicles. It not only helps with sex differentiation during fetal development but also supports the changes that occur during puberty and adulthood. Libido – DHT supports a healthy sex drive. Men with optimal levels of the hormone report a far stronger drive than men with lower levels. Prostate Health – Men with balanced levels of DHT may have fewer prostate health issues. Cognitive Function – One study indicated that administering DHT to men between 34 and 70 resulted in memory improvements. The androgenic properties of the hormone encouraged the retrieval of stored memories and the archiving of new ones. Low/lower levels of DHT were linked to a decline in cognitive function in elderly men. Blood Sugar Management – Higher levels of DHT help to reduce the risk of diabetes by controlling sugar levels and preventing hyperglycemia. DHT can improve insulin sensitivity, support efforts to lose weight, and may provide adjunctive support in treating diabetes.  Cardiovascular Health – Men with coronary artery disease may benefit from higher levels of DHT since lower hormone levels have been shown to increase the risk of cardiovascular disease. It may be a simple association – higher levels of DHT might lower the mortality associated with heart disease. Stroke Risk – Researchers followed a group of men for six years and learned that higher levels of DHT and testosterone seemed to lower the risk of stroke.  Depression – In one study, men who used finasteride, a drug that blocks 5-AR and, thus, generates lower levels of DHT, had higher rates of depression than a control group. DHT may well be necessary to support mental and emotional health. Anti-Aging – Higher levels of DHT, testosterone, and estradiol seem to slow the decline associated with aging. Lower levels of all three hormones brought about cellular changes seen in the elderly. Higher levels were associated with “younger” cellular function. Bone and Skeletal Health – Along with estradiol, appropriate levels of DHT support and maintain bone density in men. DHT – The Downside The DHT story is firm but not universally positive. The drawbacks of DHT must be considered. Baldness – Hair loss is probably the number one DHT—harmful in the minds of most men who are involved in testosterone therapy. Studies have shown that higher levels of DHT are linked to increased male-pattern baldness. In women, elevated levels of DHT can lead to male-like hair growth patterns. Cancer – DHT is critical for the normal development of the prostate, but high hormone levels have been associated with prostate cancer risk. However, studies on DHT and prostate cancer are contradictory. Acne – Inflammatory acne flares have been linked to DHT.  DHT – The Bottom Line: A Friend or Foe? For men, DHT is a friend and an important one. However, like virtually every hormone in the body, the key to health is balance. If DHT levels drop too far, men open themselves to low libido.  DHT is not likely to be tested in most men undergoing testosterone replacement therapy. Some clinicians fail to recognize the importance of DHT for men’s health and libido, so they fail to monitor it. It’s entirely possible, even likely, that some men are not obtaining the maximum benefits of testosterone replacement because (unbeknownst to them) their DHT levels are not optimal.  DiscountedLabs.com offers a highly affordable DHT test to help you determine if your body is producing sufficient DHT. The DHT test is quick, easy to administer, and reliable.   How to Increase DHT There are natural ways to boost DHT levels if one is not on a testosterone replacement protocol. Here are a few things that can be done. Exercise more, particularly resistance training and high-intensity training. Increase your intake of caffeine, creatine, or green tea supplements. Boost the amount of zinc in your diet via the food you eat or a supplement. Take a DHEA supplement if your DHEA blood level is low. Get a DHEA blood test Lose weight. Optimize your testosterone blood level, which is low. Last but not least, use a scrotal testosterone cream. Applying compounded (alcohol-free) testosterone cream to the testicular skin has increased DHT considerably. Using a DHT Blocker to Lower DHT It should be clear that most men have no reason to suppress their DHT levels. However, Propecia is regularly prescribed as a DHT blocker for men anxious about losing their hair, specifically to address male pattern baldness (a.k.a. androgenic alopecia). As was noted, Propecia will stop or suppress the 5-AR activity that produces DHT, thereby reducing DHT production. By blocking or slowing the work of 5-AR, one of the possible adverse side effects that DHT can have, male pattern baldness, may be prevented or arrested. Unfortunately, there is scientific evidence that some men who take this medication may risk lowering their libido and mood. In many cases, using DHT blockers like finasteride can help you to slow down or stop androgenic hair loss and even stimulate growth, allowing people to slow down or prevent hair loss and maintain a full head of thicker, healthier hair well into their 40s, 50s, and 60s. Topical finasteride is not FDA-approved yet but has shown promise in clinical studies. It can be sold by compounding pharmacies with a prescription. For reasons still not clearly understood, this medication can produce a syndrome in some men very similar to those symptoms associated with hypogonadism. Loss of libido, weak erections, malaise, and fatigue plague many men even after they have stopped using the drug. While it’s true that no one wants to lose their hair, no man wants to wind up with what has come to be known as post-finasteride syndrome. With proper attention, DHT can be a friend and ally in the search for optimal health. Don’t fear it; accept it and have it work to your advantage. Conclusion Navigating the intricate landscape of DHT and its role in men's health requires a nuanced understanding that balances the pros and cons. While concerns like male pattern baldness and potential links to certain health issues cannot be overlooked, the substantial benefits of DHT in areas like sexual health, cognitive function, and metabolic regulation highlight its critical role. The key lies in achieving hormonal equilibrium and ensuring that DHT levels are maintained within an optimal range. For those considering testosterone replacement therapy or DHT blockers, it's crucial to make informed decisions based on a comprehensive understanding of DHT's impact and the latest scientific research. At DiscountedLabs.com, we offer affordable and reliable DHT testing, empowering you to make the best choices for your health and wellbeing. Remember, DHT is not just a hormone to be managed but a vital component of a balanced and healthy male physiology.   Buy Your DHT TEST on DiscountedLabs.com