Page 3 - Testosterone Replacement Monitoring Tests

Embarking on the path of Testosterone Replacement Therapy (TRT) often evokes a blend of enthusiasm and concern among men. The allure of renewed vigor, heightened sexual desire, and robust muscle growth is enticing. However, there are a lot of less well-known aspects that your healthcare provider might not immediately disclose. For instance, were you aware that TRT could affect your fertility or exacerbate your sleep apnea? While TRT heralds a new dawn for many, it doesn’t offer a universal remedy. In light of this, we have meticulously curated a comprehensive list of 18 pivotal aspects that might elude your doctor's attention but are indispensable for you to grasp. Venture further to unearth the profundities of TRT. Low Blood Levels of Testosterone and Associated Risks: < 450 ng/dl (15.3 nmol/l) - Risk of metabolic syndrome Reference: Dhindsa, S., Miller, M. G., McWhirter, C. L., Mager, D. E., Ghanim, H., Chaudhuri, A., & Dandona, P. (2010). Testosterone concentrations in diabetic and nondiabetic obese men. Diabetes Care, 33(6), 1186-1192. PubMed < 400 ng/dl (15.3 nmol/l) - Venous leakage (internal penile damage) risk Reference: Yassin, A. A., & Saad, F. (2017). Testosterone Deficiency and Testosterone Treatment in Older Men. Gerontology, 63(2), 144–156. PubMed < 350 ng/dl (11.9 nmol/l) – All-cause death risk and anemia risk Reference: Khaw, K. T., Dowsett, M., Folkerd, E., Bingham, S., Wareham, N., Luben, R., ... & Day, N. (2007). Endogenous testosterone and mortality due to all causes, cardiovascular disease, and cancer in men. Circulation, 116(23), 2694-2701. PubMed < 300 ng/dL (10.2 nmol/L) - Lowered libido, weight gain & Diabetes risk increased Reference: Traish, A. M., Saad, F., & Guay, A. (2009). The dark side of testosterone deficiency: I. Metabolic syndrome and erectile dysfunction Journal of Andrology, 30(1), 10-22. PubMed < 300 ng/dL (10.2 nmol/L): Quartile risk of fractures (osteoporosis), memory-related issues and depression risk increases Reference: Orwoll, E., Lambert, L. C., Marshall, L. M., Phipps, K., Blank, J., Barrett-Connor, E.,... & Cummings, S. (2006). Testosterone and estradiol are common among older men. The Journal of Clinical Endocrinology & Metabolism, 91(4), 1336-1344. PubMed < 250 ng/dl (8.5 nmol/l): Arterial plaque (arteriosclerosis) & sleep quality affected Reference: Vlachopoulos, C., Ioakeimidis, N., Miner, M., & Aggelis, A. (2014). Testosterone deficiency: a determinant of aortic stiffness in men Atherosclerosis, 233(1), 278-283. PubMed < 235 ng/dl (8.0 nmol/l) hardening of arteries (dialysis patients) Reference: Carrero, J. J., Qureshi, A. R., Parini, P., Arver, S., Lindholm, B., Bárány, P., ... & Stenvinkel, P. (2009). Low serum testosterone increases mortality risk among male dialysis patients. Journal of the American Society of Nephrology, 20(3), 613-620. PubMed < 200 ng/dl (6.8 nmol/l) morning erections decrease Reference: O'Connor, D. B., Lee, D. M., Corona, G., Forti, G., Tajar, A., O'Neill, T. W., ... & EMAS Study Group. (2011). The relationships between sex hormones and sexual function in middle-aged and older European men. The Journal of Clinical Endocrinology & Metabolism, 96(10), E1577-E1587. PubMed < 150 ng/dl (5.1 nmol/l) - Increased inflammation (TNF-alpha) Reference: Malkin, C. J., Pugh, P. J., Jones, R. D., Kapoor, D., Channer, K. S., & Jones, T. H. (2004). The effect of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. The Journal of Clinical Endocrinology & Metabolism, 89(7), 3313-3318. PubMed The Unspoken Implications of TRT Your doctor might overlook mentioning certain ramifications when you commence Testosterone Replacement Therapy (TRT): Fertility and TRT Sperm Count Drop: TRT lowers the levels of Luteinizing Hormone (LH) and Follicle Stimulating Hormone (FSH), two hormones that help make sperm. If preserving fertility is a priority, discuss with your healthcare provider incorporating Clomiphene or hCG into your TRT regimen. Hematological Effects Blood Viscosity Increase: TRT can escalate your blood's hematocrit level, thereby increasing its viscosity. Although some practitioners may advise halting TRT, this side effect can be managed adeptly through blood donations or therapeutic phlebotomy. Beware; frequent blood donations might deplete iron levels and induce fatigue. Impact on Natural Testosterone Production Suppression of Endogenous Testosterone: TRT suppresses your body’s natural testosterone synthesis, which may rebound anywhere between a few weeks and six months post-cessation. The Multifaceted Benefits and Varied Efficacy of TRT Muscle Mass, Fat Reduction, and Sexual Health Sex Drive and Physique Enhancement: TRT predominantly augments libido, muscle mass, and fat metabolism in men. However, its effectiveness varies, and meticulous dosage and frequency adjustments along with side effect management are imperative. It’s not a panacea. Administration Techniques Methods of Injection: Contrary to what most people think, testosterone can be injected superficially (IM) or deeply (subcutaneously) into the muscle using a 1/2-inch, 27-29-gauge insulin syringe. Topical Testosterone Efficacy of Gels and Creams: Testosterone gels and creams are efficacious but often under-dosed by physicians. More concentrated compounded products or dosage adjustments based on blood levels can rectify this. Dosage Frequency Optimized Injection Schedules: Shifting from biweekly 200mg injections to weekly 100mg or twice-weekly 50mg dosages can often yield better results. Addressing Concerns and Optimizing TRT Outcomes Sleep Apnea and TRT Sleep Apnea Dynamics: TRT could exacerbate central sleep apnea but might alleviate obstructive sleep apnea over time as weight loss occurs. Erectile Function Erectile Function and Libido: TRT enhances erectile function and libido in a majority of men. Some may benefit from adjunctive low-dose daily Cialis, which also harbors cardiovascular advantages. Self-Monitoring and Telemedicine Monitoring Blood Tests: Companies like DiscountedLabs.com enable self-monitoring of blood tests without a doctor visit. Moreover, telemedicine facilitates access to testosterone doctors nationwide, albeit mostly without insurance coverage. Debunking Misconceptions and Enhancing TRT Knowledge Prostate Health and Cardiovascular Effects Prostate Cancer and Heart Attacks: Contemporary evidence refutes the notion that TRT triggers prostate cancer or heart attacks, though vigilant monitoring is crucial for optimal cardiovascular outcomes. Community Support and Knowledge Sharing Leveraging Online Communities: Engage with seasoned TRT users on platforms like the ExcelMale forum or Testosterone Replacement Discussion Facebook group to broaden your understanding. Comprehensive Testing Holistic Blood Analysis: Ensure your doctor conducts a thorough blood analysis encompassing total and free testosterone, DHT, thyroid function, and prolactin (especially for those with extremely low T levels) to rule out pituitary adenomas. Insurance, Professional Expertise, and Addressing Common Hurdles Insurance and TRT Insurance Coverage: Insurance coverage for TRT products is often restrictive, but utilizing a compounding pharmacy can be a viable alternative. Expertise in TRT Management Urologists Leading the Charge: The burgeoning expertise of urologists in TRT management is notable, with extensive TRT-centric discussions now a staple at urology conferences. Identifying and Addressing Co-morbidities Co-morbid Conditions: Men with co-existing health issues may encounter challenges in reaping TRT benefits, warranting a thorough cardiovascular assessment for those experiencing water retention and hypertension. Estradiol Management Misconceptions About Estradiol: People often get the wrong idea about this hormone, which plays a big part in libido, bone health, and brain function, because it is not given enough attention when it comes to management. Emerging evidence suggests aromatase inhibition might be unnecessary in TRT management. Armed with this extensive knowledge, you’re now better positioned to make informed decisions on your TRT journey. Remember, individualized consultation with healthcare professionals is indispensable for optimizing your TRT experience.    

Although testosterone frequently overshadows estradiol, a hormone more commonly associated with women, estradiol plays a significant role in men's health. Derived from testosterone through a process known as aromatization, estradiol contributes to various physiological aspects in men. Although it's crucial for maintaining bone density, its role in sexual health, body composition, and other health parameters is subject to ongoing discourse. Here, we delve into the dynamics of estradiol in men, its implications, and the importance of accurate measurement. Understanding Estradiol in Men The hormone estradiol, although present in smaller quantities in men compared to women, is produced through the aromatization of testosterone in liver, fat, and other cells. This conversion is nature’s design, hinting at a purpose behind it. Besides promoting bone health, estradiol’s influence on men's libido, body composition, and other factors is a hot topic among researchers. Excessive levels of estradiol, especially alongside low testosterone levels, could lead to conditions like gynecomastia (enlarged breasts in men). Hormonal Balance: The HPT Axis The Hypothalamic-Pituitary-Testicular (HPT) axis is a hormonal cascade that adjusts testosterone production based on the levels of testosterone and estradiol in the body. When either hormone level goes up too high, the HPT axis responds by decreasing the production of testosterone to keep hormone levels in balance. Aromatase Inhibitors: Boon or Bane? Aromatase inhibitors (AIs) stop the production of estradiol and are often given to people who are getting testosterone replacement therapy (TRT) to help them look younger and stay healthy. While higher estradiol levels could potentially cause gynecomastia and water retention, there's speculation, albeit without scientific backing, linking high estradiol levels to erectile dysfunction. The use of AIs is thought to mitigate these issues by lowering estradiol levels. However, the exact threshold of estradiol levels in men, beyond which it could be detrimental, remains undefined. Unveiling the Optimal Range Recent studies have started to shed light on estradiol's optimal range. For instance, levels below 20 pg/ml have been associated with increased bone loss, higher fat mass, and diminished sexual function in men. It is very important to get a correct reading of estradiol, and it is better to use a sensitive estradiol test (LC/MS assay) instead of the more common ECLIA-based test to avoid getting wrongly high estradiol readings from things like CRP (C-reactive protein). Estradiol’s Diverse Effects: A Closer Look 1. Bone Density: A study showed that estradiol levels below 11 pg/ml were linked to increased bone loss in men, emphasizing estradiol's role in bone health (Source). 2. Libido and Erectile Function: One groundbreaking study revealed that lower estradiol levels were correlated with increased body fat and a decrease in sexual desire and erectile function (Source). 3. Mortality Rate: A study highlighted that men with estradiol levels either below 21.80 pg/ml or above 30.11 pg/ml had a higher mortality rate, indicating a potential sweet spot for estradiol levels (Source). 4. Testosterone Therapy: In men undergoing TRT, elevated estradiol levels were associated with heightened libido, suggesting a nuanced interplay between testosterone and estradiol (Source). Conclusion The journey to demystify estradiol's role in men is ongoing. While its importance in bone health is well acknowledged, the hormone's broader impact on male physiology is gradually being unraveled. Accurate estradiol measurement and a deeper understanding of its optimal range could pave the way for enhanced men's health management, particularly for those undergoing testosterone replacement therapy.     Here is a more detailed discussion on estradiol in men: Click here   How to Get a sensitive estradiol test  

Starting Testosterone Replacement Therapy (TRT) is a significant decision that can have a profound impact on your health and well-being. While it offers numerous benefits, like enhanced mood, improved sexual performance, and increased muscle mass, there are also potential side effects and nuances that your healthcare provider might not fully explain. Below, we delve into critical aspects of TRT that every man should be aware of. But first, did you know that you can easily and affordably monitor your testosterone levels through DiscountedLabs.com? It's an excellent way to keep track of your health without the hassle of a doctor's visit. Table of Contents Impact on Sperm Count How TRT Affects Your Fertility Blood Viscosity and Hematocrit Managing Increased Red Blood Cells Shutdown of Natural Testosterone Production Recovery Post TRT Dose and Effectiveness TRT is Not a Magic Bullet Different Injection Methods Subcutaneous vs. Intramuscular Testosterone Gels and Creams Topical TRT: Right Dose, Right Results Optimal Injection Frequency The Shift Towards Frequent Dosing Sleep Apnea TRT and Sleep Quality Erectile Function and Libido The Added Benefits and Limitations Monitoring Your Blood Tests Taking Charge of Your Health Telemedicine for TRT Access to Expertise Prostate Cancer and Heart Attacks Debunking the Myths Community Support You're Not Alone Important Blood Tests Beyond Total Testosterone Insurance Limitations Navigating the System Consult a Urologist The Go-To Experts on TRT Comorbidities Risks and Workarounds The Estradiol Obsession Re-Thinking Estradiol Management Impact on Sperm Count How TRT Affects Your Fertility One aspect of TRT that is often overlooked is its effect on fertility. TRT reduces levels of LH (Luteinizing Hormone) and FSH (Follicle Stimulating Hormone), which are crucial for sperm production. If you plan on having children, it's essential to discuss fertility preservation options with your healthcare provider. Treatments like clomiphene or the addition of hCG can be useful. Blood Viscosity and Hematocrit Managing Increased Red Blood Cells TRT may lead to an increase in hematocrit, or the amount of red blood cells in your blood, thereby making it thicker. While some doctors may suggest pausing TRT, this condition can be managed through blood donations or therapeutic phlebotomy. However, frequent blood donations can lead to iron depletion and fatigue. Learn more about managing high hematocrit here. Shutdown of Natural Testosterone Production Recovery Post TRT Once you're on TRT, your natural testosterone production will decline. Usually, your body can recover its testosterone levels within a few weeks to six months after stopping TRT, but it's essential to know that this therapy isn't a temporary commitment. Dose and Effectiveness TRT is Not a Magic Bullet Though TRT can dramatically improve quality of life by enhancing sex drive, muscle mass, and fat loss, the effectiveness varies from person to person. Factors like dose, frequency, and side effect management play a crucial role. Learn about the average time to see benefits. Different Injection Methods Subcutaneous vs. Intramuscular There's a common misconception that testosterone must be injected deep into the muscle. However, you can also use a 1/2 inch 27-29 gauge insulin syringe for subcutaneous injections. Read more about injection methods here. Testosterone Gels and Creams Topical TRT: Right Dose, Right Results Gels and creams offer a less invasive way to administer testosterone, but the effectiveness depends on the right dose and concentration. Doctors often miss this, so make sure you monitor your levels closely. Optimal Injection Frequency The Shift Towards Frequent Dosing Traditionally, doctors prescribed testosterone injections at 200 mg every two weeks. However, many are moving towards more frequent dosing schedules, like 100 mg per week or even 50 mg twice per week, using insulin syringes. Sleep Apnea TRT and Sleep Quality Be cautious if you have central sleep apnea, as TRT can worsen this condition. However, weight loss achieved through TRT may improve obstructive sleep apnea over time. Erectile Function and Libido The Added Benefits and Limitations While TRT generally improves libido, the results regarding erectile function are mixed. Some men also use low-dose Cialis for additional cardiovascular benefits. Read more about the benefits of Cialis. Monitoring Your Blood Tests Taking Charge of Your Health One of the great advantages of modern technology is that you can monitor your own blood tests via DiscountedLabs.com, without needing a doctor's appointment. Telemedicine for TRT Access to Expertise For those living in areas without easy access to a TRT specialist, telemedicine is a viable option. Just note that most telemedicine doctors don't accept insurance. Prostate Cancer and Heart Attacks Debunking the Myths Contrary to common belief, TRT has not been proven to cause prostate cancer or heart attacks. Proper monitoring of hematocrit, HDL, and blood pressure is crucial, however. Community Support You're Not Alone Don't underestimate the value of community support. Platforms like Excel Male Forum offer a wealth of shared experiences and advice from men who have been on TRT for years. Important Blood Tests Beyond Total Testosterone Many doctors only measure total testosterone and often neglect other important markers like free testosterone, DHT, and thyroid function. Ensure these are part of your monitoring plan. Insurance Limitations Navigating the System Most insurance companies have limitations on which TRT products they cover. You can bypass insurance restrictions by going through a compounding pharmacy. Consult a Urologist The Go-To Experts on TRT Urologists are becoming increasingly knowledgeable about TRT, making them an excellent resource for anyone considering this treatment. Comorbidities Risks and Workarounds Some men might not see the benefits of TRT due to other health issues, such as metabolic disorders that can lead to water retention and high blood pressure. A full work-up with a cardiologist is advisable for these men. The Estradiol Obsession Re-Thinking Estradiol Management Many men obsess about their estradiol levels and are often prescribed high doses of aromatase inhibitors, which may not be necessary. Learn more about the role of estradiol in men here. In conclusion, TRT is a multifaceted treatment that requires proper understanding and management. Keep yourself informed and consider using DiscountedLabs.com for your testosterone level monitoring. Take control of your health today!

Testosterone, a vital hormone predominantly found in males, plays a crucial role in various physiological processes such as sexual development, muscle growth, bone density, and overall well-being. Recent studies have raised concerns about a decline in serum testosterone levels among adolescents and young adult men in the United States. This article aims to explore the potential causes, implications, and scientific evidence surrounding this phenomenon. Factors Contributing to Declining Testosterone Levels in Young Men Lifestyle Changes Sedentary behavior, unhealthy dietary patterns, and an increase in screen time have been linked to lower testosterone levels. Lack of physical activity and poor nutrition can lead to weight gain, which is associated with reduced testosterone production [1]. Endocrine Disruptors Exposure to endocrine-disrupting chemicals (EDCs) such as phthalates, bisphenol A (BPA), and pesticides has been suggested as a potential contributor to declining testosterone levels. These chemicals, commonly found in plastics, personal care products, and certain foods, can interfere with hormonal balance and disrupt testosterone synthesis [2]. Stress and Mental Health Chronic stress and mental health disorders, including depression and anxiety, may negatively impact testosterone production. Elevated cortisol levels, often associated with stress, can suppress testosterone synthesis [3]. Obesity and Insulin Resistance The rising prevalence of obesity and insulin resistance among adolescents and young adults has been linked to lower testosterone levels. Excess body fat can promote the conversion of testosterone into estrogen, leading to hormonal imbalances [4]. Implications of Declining Testosterone Levels Sexual and Reproductive Health Testosterone is essential for normal sexual function, including libido, erectile function, and sperm production. Declining testosterone levels may contribute to sexual dysfunction and reduced fertility in affected individuals. Physical Health Testosterone plays a crucial role in maintaining muscle mass, bone density, and overall physical well-being. Decreased testosterone levels may lead to decreased muscle strength, increased risk of osteoporosis, and compromised overall health. Psychological Well-being Testosterone influences mood, cognition, and overall psychological well-being. Low testosterone levels have been associated with symptoms such as fatigue, depression, irritability, and reduced quality of life. Scientific Evidence and Studies A study published in the Journal of Clinical Endocrinology & Metabolism in 2006 analyzed data from the National Health and Nutrition Examination Survey (NHANES) and found a significant decline in testosterone levels among men aged 20-74 years between 1988 and 2004 [5]. Another study published in JAMA Internal Medicine in 2020 examined testosterone levels in over 4,000 young men aged 15-39 years from 2009 to 2016. The findings indicated a substantial decline in testosterone levels during this period [6]. Research published in the journal Environmental International in 2020 explored the association between phthalate exposure and testosterone levels in young men. The study suggested that higher urinary phthalate metabolite concentrations were associated with lower testosterone levels [7]. Conclusion The decline in serum testosterone levels among adolescents and young adult men in the USA is a concerning trend with potential implications for sexual and reproductive health, physical well-being, and psychological functioning. Lifestyle factors, endocrine disruptors, stress, obesity, and insulin resistance are among the factors contributing to this decline. Further research is needed to understand the extent of the issue and develop strategies to address and mitigate the potential consequences. Buy the most affordable testosterone test in the country on DiscountedLabs.com References: Araujo AB, Dixon JM, Suarez EA, et al. Clinical review: Endogenous testosterone and mortality in men: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2011;96(10):3007-3019. Haider A, Yassin A, Doros G, Saad F. Effects of long-term testosterone therapy on patients with "diabesity": results of observational studies of pooled analyses in obese hypogonadal men with type 2 diabetes. Int J Endocrinol. 2014;2014:683515. Morales A, Bebb RA, Manjoo P, et al. Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline. CMAJ. 2015;187(18):1369-1377. Almeida OP, Hankey GJ, Yeap BB, et al. Low free testosterone concentration as a potentially treatable cause of depressive symptoms in older men. Arch Gen Psychiatry. 2008;65(3):283-289. Travison TG, Araujo AB, O'Donnell AB, et al. A population-level decline in serum testosterone levels in American men. J Clin Endocrinol Metab. 2007;92(1):196-202. O'Connor DB, Archer J, Wu FC. Effects of testosterone on mood, aggression, and sexual behavior in young men: a double-blind, placebo-controlled, cross-over study. J Clin Endocrinol Metab. 2004;89(6):2837-2845. Hammoud A, Gibson M, Peterson CM, et al. Impact of male obesity on infertility: a critical review of the current literature. Fertil Steril. 2008;90(4):897-904.

Table of Contents SHBG and the Free Testosterone Relationship What Causes High SHBG? Other factors that can contribute to high SHBG include:   Get Your Levels Checked: SHBG Test, Free & Total Testosterone Test How to Lower SHBG Levels: Very Low SHBG : Low SHBG has also been associated with: Is SHBG an Enemy of Hormone? - Emerging Studies References: Testosterone is the primary and dominant male hormone. It is responsible for numerous functions within the human body in men and women, and when levels are too low, it can lead to multiple health issues. Unfortunately, as many know, testosterone levels naturally decline as we age. Numerous external factors can contribute to lower levels of testosterone. In either case, age or external, symptoms occur, problems arise, and solutions are needed to stop the decline. For many men, testosterone replacement therapy (TRT) is the answer to this problem.  Men should ensure that their testosterone free and total, estradiol and other hormone factors are within normal levels. One of those hormone tests to monitor is the Sex Hormone Binding Globulin (SHBG) test.   SHBG and the Free Testosterone Relationship   When our body produces testosterone or provides it exogenously, a set level of testosterone flows through the body. This testosterone blood level can be measured precisely through a simple blood test aptly referred to as the Total Testosterone blood test. For most adult men, when testing their total testosterone, if it falls in the 350 ng/dl to 1100 ng/dl range, this will be considered medically optimal. Such individuals, even exhibiting low testosterone symptoms, will often not be prescribed TRT. In some cases, this may be a correct diagnosis; in other cases, symptoms exist for different reasons, but in most cases, something else is at play, which makes SHBG important.   While useful, measuring total testosterone is only useful with also measuring Free Testosterone. Free testosterone is a small fraction of your total testosterone. It is often referred to as "unbound," meaning the testosterone your body will use for its intended androgenic function. Free testosterone is so important that if your total testosterone levels are within range, if free testosterone levels are low, in most cases, the man will be symptomatic of low testosterone. This issue is often due to high levels of SHBG in the body.   For this reason, many men will attempt to lower their SHBG or even fret over it. However, SHBG serves an essential purpose. As is with estrogen, too much can be problematic, but so can too little. SHBG is no different.   Of all the testosterone flowing through your body, only 2% is what we can refer to as unbound or free testosterone. From a layman's perspective, to increase free and unbound testosterone, they'd need to increase their total testosterone. Unfortunately, it doesn't always work that way – it often helps and often fixes the issue, but not always – and here's why: our testosterone is bound to albumin and sex hormone-binding globulin (SHBG). Approximately one-third of total testosterone binds to albumin, and the rest to SHBG.   Albumin is a protein that binds testosterone, and we can say it does so loosely. This protein carries testosterone through the bloodstream and releases it as needed. The testosterone detaches and becomes what's often referred to as bioavailable or free testosterone. The testosterone that separates from albumin becomes the testosterone that influences your body's functions from sex organs, muscle tissue, brain function, and a host of other areas of bodily function. Testosterone attached to SHBG cannot do this; it is attached and does not detach.   What Causes High SHBG?   As testosterone attached to SHBG is relatively useless, if SHBG levels increase within the body, there will be more attaches and less free testosterone to circulate. Conversely, lower levels of SHBG are associated with higher levels of free testosterone, which is often associated with positive influences on bodily functions, such as libido, mood, muscle mass, etc.   Numerous factors influence how much sex hormone-binding globulin we have in our bodies. Age is one of the primary factors that affect SHBG. Often as we age, SHBG levels increase, and as a result, free testosterone levels go down. Even if our total testosterone levels remain high or optimal, our bioavailable testosterone decreases if SHBG levels increase.   Other factors that can contribute to high SHBG include: Fatty Liver Excessive or what we might call chronic alcohol consumption can lead to a fatty liver and impending higher levels of SHBG and corresponding lower levels of free testosterone. The disease can also be a factor, such as cirrhosis or cancer. Thyroid issues An underactive and overactive thyroid can lead to elevated SHBG, not to mention issues associated with the thyroid. Overactive thyroid or hyperthyroidism is often associated with graves' disease, thyroid nodules, or thyroiditis. It can also exist due to abuse of thyroid medications, such as Cytomel (T3). Underactive thyroid or hypothyroidism may be caused by inflammation of the thyroid gland, pituitary damage, too little iodine in the diet, or genetic factors, along with other possible reasons. Elevated estradiol High levels of estradiol can occur for numerous reasons, which are not limited to using certain antibiotics, some mental health medications, obesity, and abuse of exogenous testosterone. Obesity & High triglycerides While not as expected of a factor for increasing SHBG, being overweight with a low lipid profile can negatively impact. Inflammation While some level of inflammation is necessary for general health in the fight against disease or injury, what we might call chronic inflammation can lead to increases in SHBG and corresponding lower levels of free testosterone   Get Your Levels Checked: SHBG Test, Free & Total Testosterone Test   Testing your SHBG levels along with both total and free testosterone is particularly important if one wants to get to the bottom of hypogonadism (low testosterone) symptoms they may be experiencing. Remember, a total testosterone test alone, which some physicians will run, is not enough. For most adult men, SHBG levels will run between 10 nmol/L and 60 nmol/L if in the optimal range. If SHBG levels are greater than 60 nmol/L and your free testosterone is less than 2% of your total testosterone, there is a good chance your SHBG levels are too high.   Discounted Labs sells several lab test panels that measure SHBG levels that you can buy without a doctor's visit:   Testosterone (Total and Free), SHBG, CBC - Hematocrit, Ultrasensitive Estradiol and PSA   Testosterone, Free, Bioavailable and Total (Upper Limit T 1,500 ng/dL) plus SHBG   CBC, CMP, TT, FT, Lipids, Prolactin, Ultra-Sensitive Estradiol, and SHBG   Testosterone, Free, Bioavailable, and Total, LC/MS (No Upper Limit) plus SHBG   As we now understand SHBG, our next question is what can be done to lower it, increasing free testosterone in the body? There is nothing we can do about aging. As each day passes, we grow older, but there are still things we can do that will improve this factor.   How to Lower SHBG Levels:   The most obvious answer to the problem of low free testosterone and high levels of SHBG is to increase testosterone. Exercise more, consume a cleaner diet, and lose weight; all of these things will increase your testosterone levels. Your levels may not increase massively, but some increase means a higher total to pull from and a greater amount of free testosterone based on the 2% fraction. If this isn't enough - perhaps you're not reaching a 2% fraction due to elevated SHBG – one may need to consider talking to their doctor about testosterone supplementation. However, even if supplementing with exogenous testosterone, the habits mentioned are good for overall health and can only have a positive impact.   Another possible solution, and one of the more commonly needed, is lowering estradiol levels in the body. We tend to think estrogen hormones are needed for females only, but they are also crucial for men, granted in smaller amounts. As it pertains to estrogen, too much estradiol can lead to elevated levels of SHBG. If testosterone levels are also low, this can lead to even more negative factors. But it's important not to get carried away as estradiol that's too low will bring with it numerous symptoms; in fact, your life could be miserable in that regard.   Many men who are at least somewhat familiar with testosterone have been wrongly been told that too much testosterone can lead to gynecomastia due to elevated levels of estrogen in the body due to the aromatization of testosterone to estrogen. But low levels of testosterone in the body with present high levels of SHBG and estradiol can have the effect of causing gynecomastia. In order to combat high levels of estradiol, avoiding certain foods, especially those that are soy-based, will be important. Equally important is living a healthy lifestyle and incorporating what was mentioned above: adequate exercise, a healthy diet, and getting enough sleep. These things will help lower estradiol. Some men will also need medical help through medications known as aromatase inhibitors if they have gynecomastia, although most men on TRT do not need an AI. Too many men have relied on aromatase inhibitors out of fear for too many years. In reality, most men who supplement with exogenous testosterone can, in fact, control estrogen via non-medicated factors.   Some studies have shown that supplementation with DHEA (Dehydroepiandrosterone) may also lower SHBG. However, more study is needed to understand this properly, as too much DHEA can prove problematic. High doses of DHEA supplements have been associated with increased estradiol, so you must speak to your doctor first before beginning such a supplementation regimen.   Very Low SHBG :   We are then left with one factor we've yet to discuss much because it isn't all that common: low SHBG, or rather, levels of SHBG that are too low. Levels of SHBG that are too low may be an indicator of other underlying health issues. This may be an indicator of a metabolic problem. Low levels of SHBG are a standard indicator of those with diabetes. It doesn't appear, as data suggests, that insulin resistance is caused by low SHBG, but it may be a useful marker. More data is currently needed on this topic.   An A1c test will be needed to know with certainty in terms of your diabetic health.   While low SHBG is not a common concern for most men, new data has produced interesting results and information. A recent study published in the Journal of Clinical Endocrinology and Metabolism provides such information.   The process showed a man with undetectable levels of SHBG and low levels of testosterone accompanied by nearly a decade of hypogonadism symptoms. They discovered a family with a missense mutation in the SHBG gene from studying this individual. Interestingly enough, they found this issue did not interfere with the individual's spermatogenesis or general gonadal development. This leads the study to conclude SHBG may not play a significant role in the maturation of the male species physiologically or sexually.   More interesting than the JCEM study is things that new data suggest may negatively impact all men. Low levels of SHBG have recently been associated with three medical conditions that are known to be the silent killers of many men: heart disease, metabolic syndrome, and diabetes. Again, currently, it is being viewed as a marker and not as direct causation, but this new information is important as it acknowledges that more studies must be done.   Low SHBG has also been associated with:   Obesity Obesity is a factor we all well understand and is an issue that leads to problems in many health areas, and often in numerous possible directions. Cushing Disease It is associated with extended exposure to high levels of cortisol. Hypothyroidism It is associated with an under-active thyroid. Excessive levels of growth hormone Exceedingly rare for most, although possible via genetic factors or abuse of exogenous forms. Abuse through anabolic steroids     Is SHBG an Enemy of Hormone? - Emerging Studies   As we mentioned, androgens like testosterone and DHEA and estrogens are transported to the sex hormone binding globulin (SHBG). SHBG is believed to keep sex hormones inactive and to control the amount of free hormones that enter cells by passive diffusion. Contrary to the free hormone hypothesis, some researchers have demonstrated that megalin, a receptor in ovaries and testicles, acts as a pathway for cellular uptake of biologically active androgens and estrogens bound to SHBG. We will see more data on this newly found receptor that actually enables the body to use hormones bound to SHBG in the near future.   In endocrinology, the body has no “harmful” or “good” hormone. Their balance and harmony with each other matters for the best health.     References:   Ding et al. Sex hormone-binding globulin and risk of type 2 diabetes in women and men. The New England Journal of Medicine. Aug 2009. Vos et al. Sex Hormone Binding Globulin Deficiency Due to a Homozygous Missense Mutation. Journal of Clinical Endocrinology and Metabolism. Sept 2014 SHBG and Free Testosterone - Everything You Need to Know Hammes et al. Role of Endocytosis in Cellular Uptake of Sex Steroids. Cell. Sept 2005  

Estradiol in Men: What is the Most Accurate Blood Test? Table of Contents Estradiol in Men: What is the Most Accurate Blood Test? Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men Objective: Design and Setting: Main Outcome Measures: Results: Conclusions: BUY SENSITIVE ESTRADIOL TEST HERE  Recent studies show the importance of estradiol in men and how low estradiol can be detrimental for not only for bone but also for sex drive. Low estradiol has also been linked to fat gain. So, physicians should be careful about treating men who are obviously being over diagnosed with high estradiol due to the use of the wrong test. This study compares the old estradiol blood test assay (ECLIA) to the more accurate sensitive one (LC/MS/MS). The sensitive estradiol test is a method for measuring estradiol levels in men (and children) using a sensitive liquid chromatography-tandem mass spectrometry (LC/MS)-based assay[2]. It is considered more accurate for men because it provides better sensitivity and accuracy at lower estradiol concentrations, which are typically found in men, as opposed to higher concentrations found in adult females[1][2]. Immunoassay-based estradiol tests, on the other hand, perform best at higher concentrations of estradiol, making them more suitable for individuals with levels in the adult-female range[2]. The sensitive estradiol test, with its greater sensitivity at lower levels, is more appropriate for men who generally have lower levels of estradiol compared to adult females[3]. Comparisons of Immunoassay and Mass Spectrometry Measurements of Serum Estradiol Levels and Their Influence on Clinical Association Studies in Men  (Source: The Journal of Clinical Endocrinology & Metabolism, Volume 98, Issue 6, 1 June 2013, Pages E1097–E110)   Immunoassay-based techniques, routinely used to measure serum estradiol (E2), are known to have reduced specificity, especially at lower concentrations, when compared with the gold standard technique of mass spectrometry (MS). Different measurement techniques may be responsible for the conflicting results of associations between serum E2 and clinical phenotypes in men. Objective: Our objective was to compare immunoassay and MS measurements of E2 levels in men and evaluate associations with clinical phenotypes. Design and Setting: Middle-aged and older male subjects participating in the population-based Osteoporotic Fractures in Men (MrOS) Sweden study (n = 2599), MrOS US (n = 688), and the European Male Aging Study (n = 2908) were included. Main Outcome Measures: Immunoassay and MS measurements of serum E2 were compared and related to bone mineral density (BMD; measured by dual energy x-ray absorptiometry) and ankle-brachial index. Results: Within each cohort, serum E2 levels obtained by immunoassay and MS correlated moderately (Spearman rank correlation coefficient rS 0.53–0.76). Serum C-reactive protein (CRP) levels associated significantly (albeit to a low extent, rS = 0.29) with immunoassay E2 but not with MS E2 levels. Similar associations of immunoassay E2 and MS E2 were seen with lumbar spine and total hip BMD, independent of serum CRP. However, immunoassay E2, but not MS E2, associated inversely with ankle-brachial index, and this correlation was lost after adjustment for CRP (C Reactive Protein- An Inflammatory marker). Conclusions: Our findings suggest interference in the immunoassay E2 analyses, possibly by CRP or a CRP-associated factor. Although associations with BMD remain unaffected, this might imply for a reevaluation of previous association studies between immunoassay E2 levels and inflammation-related outcomes. BUY SENSITIVE ESTRADIOL TEST HERE   

Table of Contents The 6 Most Popular Discounted Lab Panels Online Why Using Direct-to-Consumer Labs? How Do Online Lab Tests Work? What Lab Tests Can You Choose? What Are the Most Popular Blood Tests Online? 1. Heavy Metal Test Symptoms of Heavy Metal Poisoning 2. Hormone and Wellness Panels for Men and Women 3. Comprehensive Fatigue Panel 4. Erectile Dysfunction ED Panel 5. Electrolyte Panel 6. Elite Male Blood Test Panel Get Your Blood Test Today! The 6 Most Popular Discounted Lab Panels Online   According to the World Health Organization, chronic diseases kill millions of people each year. Diabetes alone accounted for nearly 1.6 million deaths in 2015. Deaths caused by neurodegenerative diseases such as dementia doubled since 2000, and this number is expected to grow in the upcoming years. Although these are alarming facts, you might be happy to find out that numerous diseases and injuries, particularly chronic illnesses, can be prevented. To prevent a disease, you first need to be aware of it. To be aware of it, you need to do the right thing and get your health checked periodically. Discovering a predisposition to the disease earlier on gives you a massive advantage. You’ll be able to follow special treatments and minimize its risks or eliminate them. But how to get tested for various diseases which might affect you? Well, one of the simplest and most efficient ways is by using direct-to-consumer labs. These are usually discount labs you can purchase online at affordable prices and have your general health checked in a matter of days. Why Using Direct-to-Consumer Labs? Direct-to-consumer labs are discounted labs sold by various companies such as DiscountedLabs.com. Many people decide to buy their lab tests instead of working with their primary physicians because this route offers numerous advantages. For example: You can choose your preferred test from hundreds of labs available online You save money since you eliminate the middle man and buy "directly from the source” and not having to pay for a doctor’s visit copay. You get your results back in just a few business days.  Your information and results are confidential and secure You can draw blood or offer a urine sample in the nearest clinic from your house You have more control over your health More and more people are taking advantage of this opportunity to buy a cheap blood test and become more aware of their health, so why shouldn’t you? How Do Online Lab Tests Work? Getting a blood test online is not rocket science. The procedure has just a few steps: 1. Order your preferred test from DiscountedLabs.com 2. Get a form which allows you to go to the nearest lab or clinic to draw blood that you can download after your purchase. 3. Have your blood samples analyzed by a Quest Diagnostics laboratory in your state or the nearest state. 4. The results will be available for you to download in 5-7 business days from the day of your lab blood draw. 5. You can visit your doctor to help you interpret these results or compare them against reference values you find online As you can see, the process is simple, confidential and secure. You don’t even have to visit your doctor for a prescription since DiscountedLabs.com provides that for you. What Lab Tests Can You Choose? There are numerous things you can test in a human body using just a blood, urine or saliva sample. For example, some of the most popular tests include a complete blood count test which tells you how much hemoglobin there is in your blood, the number, and type of your blood cells, etc. You can also go for a pregnenolone test or a cheap testosterone test to determine your testosterone levels. Cheap blood tests are also available, and they can show information about your cholesterol levels, triglycerides, inflammation biomarkers and more. Buying a testosterone test online is increasingly popular especially if you’re a bodybuilder and you want to monitor your T levels or if you think you have testosterone deficiency. DiscountedLabs.com offers dozens of affordable tests for both men and women, so you have a lot of options at your disposal when it comes to taking care of your health. What Are the Most Popular Blood Tests Online? If you’re buying for the first time and you don’t know what to focus on, keep reading to find out a list of some of the most popular direct-to-consumer labs you can buy today. These tests can be obtained using a discounted labs coupon to help you save some money in the process. Here is a way to compare all discounted lab panels to see which one is best for you. 1. Heavy Metal Test The dangers of having heavy metals in your body are real. The heavy metals category includes mercury, arsenic, cadmium, lead and other types of toxic substances. These elements can stick to your bones and organs, causing serious health problems in the long run. The body can easily eliminate trace amounts of heavy metals regularly. However, if you get too high of a quantity of arsenic, for example, you're exposed to serious health risks. Lead is one of the most poisonous heavy metal out there. It can cause brain damage, depression, anxiety, and even panic attacks. Testing for heavy metals can be done using a single blood sample or a urine sample. The Heavy Metals Profile I is performed using a blood sample, and it determines the levels of arsenic, mercury, and lead in your body. There are two more tests sold by DiscountedLabs such as the heavy metal profile II and the urine test. These also come at affordable prices and allow you to discover the levels of cadmium, lead, and arsenic in your system. Symptoms of Heavy Metal Poisoning Having a high amount of toxic metals in your body puts you in a risky situation, so you need to see your doctor immediately if this happens. Moreover, you’ll be able to experience certain symptoms along the way, and you shouldn’t ignore them. These symptoms depend on the type of metal which caused the poisoning. For example, these symptoms are common among people: l Stomach pain l Diarrhea l Nausea l Dizziness l Tingling in your feet l Weakness and headaches l Vomiting Some of these symptoms are your body's desperate attempt to eliminate the accumulated heavy metals. Help your body by getting tested for heavy metals immediately and find out if you're at risk. 2. Hormone and Wellness Panels for Men and Women Any hormonal imbalance you might experience can drastically influence your health. For example, testosterone deficiency can lead to poor sex drive and even symptoms of anxiety and depression in men of all ages. Instead of looking for “testosterone testing near me” on Google, you can order a testosterone test online and have your hormonal levels checked quickly. In women, estrogen levels are the most important. One of the most popular estrogens is estradiol. This hormone directly influences mood, cognition, sex drive, libido, and other functions in women. It is also possible to check the estradiol levels for men and see if they are elevated. Very high estradiol levels in men might be caused by testosterone replacement therapy. This is a rare but known side effect of TRT, but it can be minimized with certain medications. Another common side effect of TRT has high hematocrit. If you’re wondering what high hematocrit mean then you should know that this is the percentage of red blood cells in the blood. An elevated hematocrit might cause various health problems in the long run. Donating blood can be the answer if you’re wondering how to lower hematocrit on TRT, donating blood can be the answer. However, you shouldn’t donate blood more often than one or two times per year because this can lower your ferritin levels which causes anemia. There are high hematocrit symptoms to which you should pay attention. For example, having high hematocrit levels can lead to: l Fatigue l Itching l Bone pain l Blurred vision l Excessive sweating As you can see, there are numerous important hormones you need to be mindful of such as testosterone, estrogen, estradiol, ferritin, etc. A complete hormone and wellness panel can make your life easier because it provides a complete overview of your health. DiscountedLabs.com sells a Complete Hormone & Wellness Panel for MEN and a Hormone & Wellness Panel for WOMEN, so pick the one suitable for you to learn more about your hormonal health. 3. Comprehensive Fatigue Panel If you feel tired after a long day at work, it’s normal to be so, especially if you also found some time to visit a local gym for half an hour. However, if you constantly feel tired, even in the morning when you wake up, then this is not normal. Diagnosing excessive fatigue is not that easy. There are numerous potential causes which need to be analyzed independently. For example, here are a few factors which might directly influence your energy levels and how tired you feel regularly: l Your thyroid function l Whether you have hyperglycemia or hypoglycemia l Your total and free testosterone levels l The amount of iron in your blood cells l The number of red blood cells in the blood l Any adrenal problems you might have One hormonal imbalance in these areas can make you feel excessively tired. Also, keep in mind that such health problems don’t get corrected on their own. You need to do a thorough health checkup and see what causes your tiredness. A comprehensive fatigue panel takes all these factors into account and analyzes multiple hormones and substances in your bloodstream. Based on the results, your doctor can make appropriate health recommendations. For example, people who have low energy levels as a result of insufficient iron in their bloodstream might need to take an iron supplement. Similarly, those who have low testosterone levels might benefit from TRT or various lifestyle changes to improve their total and free testosterone levels. 4. Erectile Dysfunction ED Panel Another commonly purchased panel is the ED blood test. Unfortunately, the prevalence of erectile dysfunction is quite high, especially among men who are 40 years old or older. However, this health condition can be treated in numerous ways. There are both invasive and non-invasive procedures as well as pills which can improve the symptoms of erectile dysfunction. Certain lifestyle changes can also improve one's erection. However, the most important thing is to know exactly what caused the ED and how to treat it efficiently. For example, having low testosterone levels can lead to erectile dysfunction in men of all ages. In this case, TRT might be the appropriate treatment method to improve libido. Similarly, high estradiol can also be linked to erectile problems. Estradiol is a female sex hormone. If there is too much (or even too little) estradiol in the bloodstream, the person in question will experience erectile dysfunction. ED can also be caused by thyroid problems. For example, the TSH, T3, and T4 are all thyroid hormones which directly influence the production of testosterone and sex drive in general. If these hormones are out of balance, one might not be in the mood for sex that often. Prolactin is another important hormone in the body. It is produced by the pituitary gland, and if it’s not secreted correctly, ED can appear in men. As you can see, there are numerous factors which influence sex drive. The Erectile Dysfunction Panel which can be bought from DiscountedLabs.com looks at all these hormones to determine which one is out of balance. All you need to do is to buy the panel online and go to your nearest lab for a blood sample. The results will be communicated to you in a few business days, and then you can begin looking for appropriate solutions to your ED problem. 5. Electrolyte Panel Electrolytes are important substances in the human body. The most popular ones are potassium and sodium. Other electrolytes include chloride and carbon dioxide. The job of electrolytes is to regulate important bodily functions such as maintaining correct blood pH, muscle and nerve function. When electrolytes go out of balance, various physical symptoms can appear. For example, too much sodium in the body makes the blood acidic. This can lead to chronic illnesses in the long run. At the same time, too much potassium can cause heart problems and other similar health conditions. The Electrolyte Panel which can be bought from DiscountedLabs.com looks at four different important electrolytes in the body such as carbon dioxide, chloride, potassium, and sodium. This is one of the most affordable blood tests online, and it requires only a small blood sample to run it. 6. Elite Male Blood Test Panel If you want to have a broader overview of your health, the Elite Male Blood Test Panel is highly recommended for you. This is one of the most comprehensive panels sold on DiscountedLabs and one of the most affordable in the United States. Using just a simple blood sample, you get to find out more information about multiple hormones, enzymes, and substances in your body such as testosterone, prolactin, thyroid hormones, IGF-1, PSA and more. This panel looks at more than ten different hormones in your bloodstream, helping you diagnose certain conditions or preventing more serious diseases. A lipid panel is also included in this package, revealing information about your good cholesterol, bad cholesterol, and triglyceride levels. Another important hormone checked by this panel is sensitive estradiol. This hormone is linked to sex drive, and if it is in high quantities, it can lead to gynecomastia which is also known as “male boobs.” The estradiol levels might increase as a result of testosterone replacement therapy. If you’re currently using TRT, you might want to get this panel to find out if you’re prone to develop gynecomastia in the future. The Elite Male Blood Test Panel also looks at your complete blood count. It analyzes your hematocrit, the number of red blood cells, the amount of hemoglobin in your bloodstream, etc. Knowing more information about red blood cells helps you determine if you’re predisposed to anemia. Similarly, having a high hematocrit can cause problems in the long run so that you can monitor this important parameter with the Elite Male Panel. Another important aspect checked by this panel is the metabolic function. More precisely, the test looks at the kidney and liver health. As you probably already know, your liver is one of the most important organs in the body. It is responsible for eliminating toxins and producing numerous hormones required for a healthy living. Once you know the state of your liver, you'll be able to make appropriate lifestyle changes to improve its function. The same story goes for your kidneys. For example, creatinine is a byproduct which needs to be excreted by the kidneys. If this process doesn't happen correctly, you can develop kidney problems in the future. The Elite Male Blood Panel helps you look at all these vital aspects and have a broader understanding of your health. Get Your Blood Test Today! As you can see, ordering direct-to-consumer labs is efficient, more affordable and saves time. You don’t have to search for “discounted labs tests near me” on Google anymore; the answer comes directly from DiscountedLabs.com.  

Testosterone replacement therapy is an important treatment option for men with low testosterone and symptomatic hypogonadism. Various formulations of exogenous (supplemental) testosterone replacement therapy exist, including oral, buccal, intramuscular, transdermal, subdermal, and nasal preparations. However, exogenous testosterone replacement therapy is a double-edged sword, posing risks to fertility due to negative feedback mechanisms on the hypothalamic-pituitary-gonadal (HPG) axis, which is the primary regulator of testosterone production and sperm production in men.  Testosterone replacement therapy (TRT) is one of the most effective ways to combat low testosterone levels, but you must understand the risks associated with the treatment. As with any hormone replacement therapy, there are a few downsides to receiving regular testosterone injections. But do these risks outweigh the benefits? That’s a decision you’ll have to make for yourself!   Testosterone replacement therapy- Target Blood Test Limits: To minimize TRT side effects, different medical guideline groups have created lab test value ranges and maximum acceptable targets . These values have been collected from three TRT guidelines and clinical practices around the United States: Hematocrit (percent of red blood cells in plasma) under 53 PSA (Prostatic specific antigen) under 3 (4 is max since doctors will not prescribe TRT at this number) Estradiol (sensitive) between 20-50 pg/mL. However, if you have high testosterone, estradiol will be "high" per Quest or Labcorp since 0.4% of total testosterone aromatizes to estradiol. Blood pressure under 135/85 Estimated Glomerular (eGFR) (kidney function) over 60 Liver enzymes not elevated over 20 percent of top value of reference range Total Testosterone over 450 ng/dL Free Testosterone equal or above 2 percent of total If donating blood to bring hematocrit down, ferritin should never under 30 ng/mL or micrograms/liter (this could lead to fatigue) Free T3 (if hypothyroid and on treatment) in the upper quartile of range. (depending on range it can be 3.7- 4.2 pg/mL) HDL over 40 mg/dL (higher TRT doses can lead to decreased HDL cholesterol) You can order these lab tests here: TRT Male Hormone/Wellness Follow-Up Panel PSA Lipid Panel Thyroid Panel    

Are you feeling sluggish, having trouble concentrating or noticing decreased libido? These are all signs that could indicate low testosterone levels. Before taking any hormone therapy, it is critical to recognize the source and assess your present health status accurately. A hormone quiz can be an effective tool for men interested in learning more about their hormones and if they may need further testing or treatment. Taking this type of quiz will help provide insight into potential imbalances within the body as well as how best to address them with natural solutions such as diet changes, lifestyle adjustments, and other therapies before turning to prescription medications. Read on to learn more about what a hormone quiz entails, its benefits, and how to get started today. Table of Contents What is Testosterone? Definition of Testosterone: What is the Hormone Quiz? Benefits of Taking a Hormone Quiz How to Get Started with a Hormone Quiz? Hormone Quiz for Low Testosterone: What Are the Symptoms of Low Testosterone (Deficiency)? Benefits of Normalizing Testosterone Determining If You Have Testosterone Deficiency Testosterone Deficiency Causes Conclusion References: What is Testosterone? Testosterone is a male sex hormone, produced primarily in the testicles. It’s responsible for many of the physical and emotional characteristics associated with manhood. Its production peaks during adolescence and early adulthood, then gradually declines with age. Definition of Testosterone: Testosterone is a steroid hormone that helps regulate reproductive organs, bone mass, muscle mass, body hair growth, fat distribution and red blood cell production. It's also known as an “androgen” because it promotes masculine traits like strength and aggression. Testosterone is a critical factor in the regulation of male sexual function, stimulating sperm production, sustaining libido, promoting erectile function, and augmenting energy levels and cognitive performance while improving mood and bolstering self-confidence. Additionally, testosterone helps to promote muscle growth and development as well as aiding weight management through its influence on metabolism rates. If you can relate to any of these, it may be beneficial to take a Hormone Quiz and assess if your testosterone levels are lower than optimal. Testosterone is a vital hormone which has implications for various aspects of health and wellbeing. Gaining knowledge about the effects of testosterone can assist in making knowledgeable decisions related to health. Gaining insight into how hormones influence your body and which lifestyle modifications could be advantageous can be achieved by taking the Hormone Quiz. What is the Hormone Quiz? The Hormone Quiz is an online questionnaire designed to help men identify potential issues with their testosterone levels. The quiz consists of a series of questions about lifestyle, health, and medical history that can provide insight into the current state of a man’s hormones. By honestly responding to the questions posed in the Hormone Quiz, males can get a precise appraisal of their hormone levels and ascertain if they require additional testing or treatment. The intent of the Hormone Quiz is to give men insight into their testosterone levels without needing a medical consultation or laboratory exams. It provides quick feedback on possible symptoms associated with low testosterone so that individuals can take action before it becomes more serious. Additionally, this quiz allows men to evaluate their own lifestyle choices and adjust accordingly for better overall health outcomes. The Hormone Quiz includes queries regarding physical activity, sleep quality, dietary habits, stress management techniques regularly employed as well as any medications taken or illnesses experienced in recent years. These are all important considerations when assessing overall hormonal balance since they can directly impact how our bodies produce hormones such as testosterone. Other items covered include age range (since hormone production tends to diminish with advancing age), family history related to hormone imbalances like diabetes and obesity, and whether there has been any significant fluctuation in weight recently which may be indicative of other underlying issues that could potentially affect one's hormonal equilibrium. The Hormone Quiz is an invaluable asset for comprehending one's hormone levels and the potential effects on wellbeing. By taking the quiz, you can gain insight into what treatments or lifestyle modifications may be beneficial to your health in the long run. By taking the Hormone Quiz, you can gain insight into potential health benefits that may be derived from making lifestyle changes or receiving treatments.   Key Takeaway: The Hormone Quiz is an efficient way for men to gain insight into their testosterone levels without the need of a doctor's appointment or laboratory tests. By answering questions about lifestyle, health and medical history honestly and accurately, individuals can get an accurate assessment of their hormone levels and take action if necessary before things become more serious. This quiz also provides an opportunity for self-reflection in terms of making healthier lifestyle choices that could positively impact hormonal balance. Benefits of Taking a Hormone Quiz Taking a hormone quiz can be extremely beneficial for men who are interested in their health and fitness. Early detection and treatment of low testosterone levels is one of the primary benefits of taking a hormone quiz. Testosterone, a key hormone for men, is responsible for the regulation of metabolism, muscle mass, bone density, libido and energy levels. Low testosterone can bring about signs such as tiredness, despondency, changes in weight and libido. By taking a simple blood test at an accredited lab through our website you will be able to detect any potential issues with your testosterone levels early on before they become more serious problems. Another benefit of taking a hormone quiz is improved quality of life and well-being due to increased energy levels and libido associated with normal testosterone production. High testosterone levels often result in greater feelings of happiness due to increased energy and improved performance, as well as a heightened libido for couples. Additionally, having adequate amounts of this important male hormone also increases sexual desire making it easier for couples to enjoy intimacy together without worrying about erectile dysfunction or lack thereof due to hormonal imbalances that come from low T-levels. Completing a hormone quiz can be an essential starting point for comprehending one's body and its requirements, granting the ability to make educated choices about self-care. With the right lab and knowledge on hand, getting started with a hormone quiz is easy - all it takes is some research into accredited labs for testing and learning more about what your results mean.   Key Takeaway: Taking a hormone quiz can be an invaluable tool for men, as it allows them to detect any issues with their testosterone levels early on before they become more serious. A hormone quiz can be a great way to identify testosterone-related issues early, helping stave off more severe health concerns and boosting vigor and libido for better day-to-day performance. How to Get Started with a Hormone Quiz? If you’re looking to take a hormone quiz, the first step is finding an accredited lab for testing. You want to make sure that the laboratory has been certified by a third-party organization such as CLIA or CAP so that your results are reliable and accurate. Once you have found an accredited lab, it’s time to get tested. The tests used in hormone quizzes typically measure levels of testosterone, estrogen, progesterone and other hormones in your blood or saliva sample. Once the laboratory has yielded your outcomes, it is imperative to comprehend their significance and consult with your physician if need be. Your doctor can help explain any abnormal test results and provide advice on how best to address them through lifestyle changes or medications. It's also important to note that while some symptoms may be caused by low hormone levels, they could also be due to other medical conditions so getting professional guidance is essential before taking any action based on test results alone. Finally, making lifestyle changes can go a long way towards improving health when dealing with low hormone levels. Eating healthy foods rich in vitamins and minerals like fruits and vegetables can help boost energy levels naturally while exercising regularly will help improve circulation which helps hormones circulate throughout the body more efficiently leading to better overall health outcomes over time. Additionally reducing stress through activities like yoga or meditation can also help balance out hormones naturally without having to resort to medication or supplements unless advised by a doctor after discussing test results further. Taking care of yourself should always be priority number one.   Key Takeaway: Discovering a certified lab is the primary step to undertaking a hormone examination, which typically assesses levels of testosterone, estrogen and progesterone. It's important to understand your results and discuss them with your doctor before making any changes - but lifestyle modifications like eating healthy foods or reducing stress can go a long way towards balancing hormones naturally. Hormone Quiz for Low Testosterone: Here is a hormone quiz for men who think they may have low testosterone symptoms: How often do you feel tired or fatigued? Rarely Sometimes Often Almost always   Have you noticed a decrease in your sex drive or erectile function? Rarely Sometimes Often Almost always   Have you experienced a decrease in your muscle mass or an increase in body fat? Rarely Sometimes Often Almost always   Have you experienced a decrease in your beard or body hair growth? Rarely Sometimes Often Almost always   Have you experienced mood changes, such as irritability or depression? Rarely Sometimes Often Almost always   Have you experienced hot flashes or night sweats? Rarely Sometimes Often Almost always   Have you noticed a decrease in your bone density or been diagnosed with osteoporosis? Rarely Sometimes Often Almost always   Have you noticed a decrease in your energy levels or motivation? Rarely Sometimes Often Almost always   Have you experienced sleep problems, such as difficulty falling or staying asleep? Rarely Sometimes Often Almost always   Have you experienced a decrease in your overall sense of well-being? Rarely Sometimes Often Almost always If you have answered 3 or 4 in at least 5 questions, then it is a good idea to talk to a doctor about testosterone testing. This quiz can be used as a preliminary tool to detect low testosterone levels, but it is important to note that a diagnosis can only be made by a medical professional. If you are experiencing any symptoms that concern you, it is best to schedule an appointment with your doctor. What Are the Symptoms of Low Testosterone (Deficiency)? A number of tests are available to assist people assess whether they are suffering any of the symptoms associated with low testosterone levels in males, which can include a wide range of signs and symptoms. One such test asks about exhaustion or fatigue, a decline in erectile function or sex desire, changes in muscle mass or body fat, mood swings, hot flashes or night sweats, changes in bone density, sleep issues, and a decline in general sense of well-being. Yet, it's crucial to keep in mind that only a doctor can provide an official diagnosis of hypogonadism, or low testosterone. Lowered sexual desire, erectile dysfunction, melancholy, low energy and appetite, altered body composition, decreased strength, decreased body and facial hair, diminished mental clarity, and decreased bone density are some of the symptoms of hypogonadism that are frequently seen. Restoring sexual desire, enhancing erectile function, enhancing mood, increasing lean body mass, strength, and stamina, enhancing bone density, and reducing fat mass are just a few of the advantages of restoring normal testosterone levels. The Androgen Deficiency in the Aged Man (ADAM) questionnaire, a screening tool, can help with the diagnosis of hypogonadism in addition to blood testing and physical examinations. [1] [4] As mentioned previously, hypogonadism is the medical term for the condition in males that is caused when the body is not producing sufficient amounts of testosterone. What most people don’t realize is that in addition to sexual desire, testosterone also affects lean body mass, strength, bone density, mental focus, mood, fat loss, and other important factors in both males and females. Common complaints for men with hypogonadism include: lower sexual desire (libido), erectile dysfunction (softer erections or lack of erections), depression, low energy and appetite, changes in body composition (lower lean body mass and higher abdominal fat), lower strength, reductions in body and facial hair, less mental focus and  decreased height and osteoporosis (decrease in bone density). Normalizing testosterone in people who have lower than normal levels has dramatic benefits, among which are increased sexual desire, lean body mass, bone density, strength, mood, motivation, mental focus, and stamina. However, these benefits can be erased if proper monitoring, dose adjustment, and appropriate choice of testosterone replacement option are not accomplished. Benefits of Normalizing Testosterone Restored sexual desire Improved erectile function Improved mood/ sense of wellbeing Increased lean body mass, strength and stamina Improved bone density Decreased fat mass Determining If You Have Testosterone Deficiency In addition to blood tests and physical examination, a brief screening instrument has also been developed by researchers at St. Louis University to aid in the diagnosis of hypogonadism. Known as the Androgen Deficiency in the Aging Male (ADAM) questionnaire:   Do you have a decrease in sex drive? Do you lack energy? Have you experienced a decrease in strength and/or endurance? Do you feel shorter? Have you lost height? (Lower bone density can decrease height.) Have you noticed a decreased enjoyment of life? Are you sad and/or grumpy? Are your erections less strong or gone? Has it been more challenging to maintain your erection throughout sexual intercourse? Are you falling asleep after dinner? Has your work performance deteriorated recently? Other questions that are usually not asked by doctors, but which I’ve found to be important are the following: Are you relating well with people around you? Are you being loving to your lover or life partner? Are you able to pay attention when someone talks to you? Note that several of the above-mentioned problems can be caused by many other issues unrelated to low testosterone. Depression, anxiety, stress, medications and/or sleep disorders can cause nine of those 10 symptoms (decrease in height would be the only item unrelated to anything but bone loss or back surgery). This questionnaire is not a perfect predictor of low testosterone and should not replace tests for testosterone blood levels. The benefit of the above questionnaire is that it may encourage some men to seek medical advice.  Then they can get their testosterone checked and have a physical examination to help determine whether they are indeed hypogonadal.   Testosterone Deficiency Causes As previously stated, hypogonadism occurs when the testicles fail to produce normal levels of testosterone. One type of hypogonadism has low testosterone levels while high LH and FSH levels. In another case, there is insufficient LH and FSH secretion to signal the testicles to produce the required testosterone. Medication such as Megace (an appetite stimulant), Nizoral (an anti-fungal agent), Prednisone (an anti-inflammatory corticosteroid), and Tagamet (an antacid) can all reduce testosterone production. Illness and aging can reduce testosterone and/or increase sex hormone binding globulin levels (SHBG). Furthermore, High prolactin hormone levels may indicate a pituitary tumor causing a drop in testosterone production. To determine the type of hypogonadism you have, your doctor must measure hormones in the HPGA cascade. The most common type of hypogonadism is low testosterone with normal or elevated FSH and LH levels, indicating that your testicles are not responding to both LH and FSH signals. This is known as primary hypogonadism. There are several possible causes for low testosterone levels • The pituitary gland, which regulates testosterone production by secreting LH, is not secreting enough LH to stimulate testosterone production by the testicles. Total testosterone would be low in this case. • The hypothalamus isn't working properly. LH levels less than 2 ng/mL indicate a lesion in this region of the HPGA. • Despite adequate LH levels, the testicles have lost their ability to produce testosterone. Despite the low testosterone level, the LH level would be high (greater than 10 ng/mL). • Infections or disease. • Prescription or over-the-counter medications, as well as street drugs (more on this later). • Foods (more on this later). . Obesity and poor sleep Environmental Factors • Mistake in the laboratory. . Biotin supplementation in high doses and using an ECLIA-based testosterone test (interference) • High prolactin levels may indicate the presence of a pituitary tumor, which impairs the production of hormones that tell your testicles to produce testosterone (rare condition, but worth noting!) • Gene defects that affect LH and FSH production.   Conclusion The hormone quiz is an invaluable tool for men to use when considering if they may have low testosterone levels. Taking the time to answer a few questions can provide insight into whether or not further testing and potential treatment are necessary. It's important that men take charge of their health, so don't wait any longer - get started on your hormone quiz today. Take control of your hormone health with DiscountedLabs.com! Our convenient online blood tests provide you with fast, accurate results without the need for a doctor's visit. References: [1] "By age 30 or 35, testosterone levels decrease by about 1% each year. This gradual drop is a normal part of aging. By age 80, half of all men have low testosterone, according to the Urology Care Foundation. But testosterone levels can fluctuate daily, and even change from hour to hour. They are highest in the morning, which is why doctors run ..." URL: https://share.upmc.com/2022/01/do-i-have-low-testosterone/ [2] "Testosterone is a hormone produced by the testicles. Testosterone affects your appearance and sexual development, stimulates sperm production and sex drive, and helps build muscle and..." URL: https://www.healthline.com/health/low-testosterone/warning-signs [3] "The truth about testosterone quiz: Low testosterone and ageing in men Health A-Z Drugs Supplements Living Healthy Mens Health Quizzes Quiz: The truth about testosterone 1 / 17 If..." URL: https://www.webmd.com/men/rm-quiz-truth-testosterone [4] "Testosterone levels generally decrease with age, so older men tend to have low blood testosterone levels. Some men have low testosterone levels. This is called Testosterone Deficiency Syndrome (TD) or Low Testosterone (Low-T). Deficiency means that the body does not have enough of a needed substance." URL: https://www.urologyhealth.org/urology-a-z/l/low-testosterone [5] "Our testosterone quiz can help determine if you have low testosterone and could benefit from treatment. Testosterone is a hormone that plays a key role in many aspects of male health, including sex drive, muscle mass and strength, and bone density." URL: https://phoenixmenshealthcenter.com/testosterone-quiz/