Men's Health

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In their study, Dr. Catalona and coworkers found that one in four patients with normal DRE and PSA levels between 4.0 and 10.0 ng/mL have prostate cancer ( JAMA. 1998 May 20; 279(19):1542-1547.) They recommend using a cutoff of 25% free PSA for this group of men to identify individuals with an increased risk of prostate cancer. They found that 95% of men with cancer (as determined by biopsy) with normal DRE and total PSA between 4.0 and 10.0 ng/mL had percent free PSA of ≤25%. Their study further indicated that 20% of men with benign disease (as determined by biopsy) with normal DRE and a total PSA between 4.0 and 10.0 ng/mL had percent free PSA greater than the 25% cutoff. The 25% free PSA cutoff detected 95% of cancers while avoiding 20% of unnecessary biopsies.

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Blood test that measures Epstein-Barr Virus (EBV) Antibodies to Early Antigen, IgG which helps in the diagnosis of EBV infection (infectious mononucleosis)

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Free and weakly bound testosterone (FWBT), also referred to as bioavailable testosterone, is thought to reflect an individual's biologically active, circulating testosterone. FWBT includes free testosterone and testosterone that is bound to albumin. FWBT does not include sex hormone binding globulin-bound testosterone. The SHBG-bound fraction is biologically inactive because of the high binding affinity of SHBG for testosterone. The rapid dissociation of “weakly bound” testosterone from albumin results in the availability of essentially all albumin-bound testosterone for steroid-receptor interaction.

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This panel includes two estradiol tests (total and free-unbound) measured by the most accurate hormone testing method: Liquid chromatography/ Mass Spectrometry. Buying these two tests separately would cost $143, so you save $32 by ordering them together in this panel.

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The glucose tolerance test is a medical test in which glucose is given and blood samples taken afterward to determine how quickly it is cleared from the blood. The test is usually used to test for diabetes, insulin resistance, impaired beta cell function, and sometimes reactive hypoglycemia and acromegaly, or rarer disorders of carbohydrate metabolism. In the most commonly performed version of the test, an oral glucose tolerance test (OGTT), a standard dose of glucose is ingested by mouth and blood levels are checked two hours later.

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This panel includes levels in urine of Total Arsenic, Inorganic Arsenic, Lead, Mercury, Creatinine and Creatinine ratios for all metals. The specimen for this test can be either Random Urine or 24 Hour Urine.

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Test Includes: Arsenic, blood; cadmium, blood; lead, blood; mercury, blood

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This panel measures the blood levels of arsenic, lead, and mercury.

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The most complete of all blood test panels for men that include: Total and Free Testosterone, Sensitive Estradiol, IGF-1, Prolactin, DHT, DHEA-S, PSA, SHBG, Lipids, CBC, CMP, and Thyroid Function.

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This panel includes hormones that have been implicated in gynecomastia by several studies. Gynecomastia is a benign enlargement of the male breast resulting from a growth of the glandular tissue of the breast. Since it causes anxiety, psychosocial discomfort and fear of breast cancer, early diagnostic evaluation is important, and patients usually seek medical attention. Causes include hormone imbalance and genetic predisposition.

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This blood test panel includes: CBC, CMP, Lipids, Testosterone (T & F), Sensitive Estradiol, TSH, Free T3, PSA, and SHBG

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Apo A-1 comprises 60% to 70% of the protein content of HDL. Apo A-1 serves as an activator of LCAT which is involved in the transport of cholesterol from peripheral tissues to the liver where it is degraded. Decreased serum HDL cholesterol levels have been reported to correlate with increased risk of coronary artery disease (CAD); however, Apo A-1 has been suggested as a better discrimination of CAD than HDL.

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There are several ways to determine if the dose/frequency of HCG while on TRT is effective: Performing a sperm count/quality test and/or measuring an upstream hormone to testosterone called 17-hydroxyprogesterone (17OH-P). TRT decreases 17OH-P and other upstream hormones due to the shut down of LH (LH is needed to activate the production of these hormones- See figure below). When using HCG plus TRT, upstream hormones like 17OH-P can be normalized. Several studies have found that 17OH-P blood level is correlated to ITT, so testing for this hormone could not only save time while optimizing HCG dose/frequency but also eliminate the need to perform testicular aspirations, a very difficult procedure to do. A 17OH-P level over 6.5 nmol/L (or 215 ng/dL) was found to normalize ITT while using HCG doses of 500 IU every other day plus testosterone enanthate injections given at 200 mg/week.

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Approximately 95% of IGF-1 and IGF-II are bound to IGFBP-3, which makes this protein the major carrier of the insulin-like growth factors in circulation. The function of the binding protein is to extend the half-life of the growth factors in the circulation.

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Renin is also called angiotensinogenase; it’s an enzyme produced by the kidneys to control aldosterone production. It’s also essential in the renin–angiotensin aldosterone system (RAAS) which maintains your body’s fluid balance and blood pressure. Aldosterone is the primary of several endogenous members of the class of mineralocorticoids in humans. Aldosterone tends to promote Na+ and water retention, and lower plasma K+ concentration.

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Aldosterone (ALD) is one of a group of connected hormones. They form the renin–angiotensin–aldosterone system; this system is activated when there is a decrease in blood flow to your kidneys following a drop in blood volume or blood pressure

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Adrenocorticotropic hormone (ACTH, also adrenocorticotropin, corticotropin) is a hormone produced in the anterior pituitary gland that stimulates the adrenal glands to release cortisol, dehydroepiandrosterone (DHEA), and aldosterone.

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Lipoprotein(a) has been called a powerful predictor of premature atherosclerotic vascular disease. As an independent risk factor for premature coronary artery disease, excess Lp(a) concentrations are associated with an increased risk of cardiac death in patients with acute coronary syndromes and with restenosis after angioplasty (PTCA) and coronary bypass procedures. In general, concentrations greater than or equal to 75 nmol/L of Lp(a) in serum are associated with a two- to sixfold increase in risk, depending on the presence of other risk factors.

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A basic panel offered at a lower cost than the full ED Panel for checking hormones related to erectile dysfunction and testosterone replacement therapy.

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Both chronically low and high levels of glutathione in the body are indicative of potentially debilitating health problems. Glutathione level is a crucial marker for many diseases, both chronic and acute. Given the importance of this protein to human health; discovering your glutathione levels could be one more way to monitor health levels, immune function, and the potential risk of diseases that have been associated with chronically low or high levels of this essential peptide.

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Basic semen analysis is also known as a sperm count test. A semen analysis measures the viability and health of male sperm. Semen is the bodily fluid that contains sperm (and other sugars and proteins) that is released during ejaculation. Semen analysis is used to measure three major sperm health factors:

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PSA circulates through the body in two ways; bound to other proteins or by itself. Unbound PSA is called free PSA. A free-PSA test will measure the percentage of unbound PSA while a PSA test is used to measure the total of free and bound PSA in the blood. The free PSA is a defective variant of normal PSA that can no longer bind to other proteins and so circulates in the blood in the free form. Although the reason why this is the case is poorly understood - patients with prostate cancer may have lower free PSA levels than those with a benign prostate condition.

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Cystatin C is a protein found in almost all the cells in the body. Cystatin C helps to regulate the activity of enzymes needed to break down bigger molecules both inside of and around those cells. Cystatin C level in the blood can be measured to determine how well the kidneys are functioning. The kidneys, liver, and spleen all work to filter the blood and excrete any waste substances as urine. This filtration process happens in a microscopic structure in the kidneys; the glomerulus. Each kidney contains approximately one-million glomeruli that function as tiny sieves to extract waste. The glomerular filtration rate (GFR) rate is a measure of how well the glomeruli are filtering blood. If the kidneys and glomeruli are impaired, the GFR could decrease. A decreased GFR can cause certain proteins to accumulate (like cystatin C and creatinine) in the blood. So, the Cystatin C blood test is used to measure circulating levels of cystatin C. The levels of cystatin C in the blood can be used to assess the glomerular filtration rate to indirectly provide an assessment of kidney function.Since the concentration of cystatin C in the blood will not change due to infection or inflammation and isn’t affected by body weight, drugs or diet - cystatin C level could be a more reliable indicator of kidney health than creatinine. 

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The PTH test is used to help identify hyperparathyroidism, to find the cause of abnormal calcium levels, or to check the status of chronic kidney disease. PTH controls calcium and phosphorus levels in the blood.

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ED Panel Includes Main Hormones Involved with Erectile Function: Prolactin, Total and Free Testosterone, Sensitive Estradiol, DHT, TSH, Free T3 and Free T4.

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This panel is popular among men who are on testosterone therapy since it offers substantial savings over ordering each of these tests separately : Complete Blood Count (CBC) ,Comprehensive Metabolic Profile ( includes eGFR ), Estradiol Sensitive, Testosterone, Total and Free, LC/MS-MS ( Accurate for all testosterone levels, uncapped), Prolactin, Lipids, and Sex Hormone Binding Globulin (SHBG)

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This test provides a more accurate measurement when total testosterone concentrations are very low (under 150 ng/dL, adequate for T testing in women) or very high (over 1500 ng/dL).

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This panel includes: Total and Free Testosterone (ECLIA method), Luteinizing Hormone (LH), and Follicle Stimulating Hormone (FSH) at substantial savings that buying each test separately.

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This panel is designed to measure the health and recovery of the Hypothalamic-Pituitary-Testicular Axis (HPTA) after attempting to normalize it spontaneously or with the use of Post-Cycle Therapy (PCT) . PCT is prescribed by some physicians for men who stop testosterone replacement therapy (TRT) or other androgens.

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Includes Hematocrit

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Lipid Profile: Evaluates the risk for developing atherosclerosis (arterial plaque) and coronary heart disease. This test includes: Total Cholesterol, Triglycerides ,HDL Cholesterol, LDL Cholesterol, Total Cholesterol/HDL Ratio

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 A prolactin blood test is used by doctors to evaluate sexual dysfunction of unknown cause in both men and women.

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Dehydroepiandrosterone (DHEA) is a hormone produced by the adrenal gland. It is also made in the brain. DHEA leads to the production of androgens and estrogens (male and female sex hormones). DHEA levels in the body begin to decrease after age 30. Lower DHEA levels are found in people with hormonal disorders, HIV/AIDS, Alzheimer's disease, heart disease, depression, diabetes, inflammation, immune disorders, and osteoporosis. Corticosteroids, birth control taken by mouth, and agents that treat psychiatric disorders may reduce DHEA levels.

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This test measures the amount of dehydrotestosterone (DHT) in the blood.  Low DHT has been associated with low libido and high DHT has been linked to acne, hair loss and benigh prostatic inflammation in a minority of men.

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This test measures Zinc levels in red blood cells (RBC). Red blood cell (RBC) analysis is an invaluable method for assessing insufficiency or excess of elements that have important functions within cells or on blood cell membranes. It may be more accurate than testing Zinc in serum.

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This is a very economical panel that includes: 1- Hematocrit: Portion of total blood volume made up of red blood cells. Testosterone replacement therapy can increase hematocrit. Hematocrit over 52 may increase blood thickness and cardiovascular risks. 2- Total and Free Testosterone (For expected total testosterone blood levels under 1500 ng/dL) by Equilibrium Analysis.

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Homocysteine is a chemical in the blood that is produced when an amino acid (a building block of protein) called methionine is broken down in the body. We all have some homocysteine in our blood. Elevated homocysteine levels (also called hyperhomocysteinemia) may cause irritation of the blood vessels. Elevated levels of homocysteine show an increased risk for (1) hardening of the arteries (atherosclerosis), which could eventually result in a heart attack and/or stroke, and (2) blood clots in the veins, referred to as venous thrombosis.

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A Magnesium RBC test can provide an earlier indicator of magnesium deficiency that a standard magnesium blood test. When levels are low, the body will pull magnesium from the cells to keep blood levels normal. In this case a magnesium blood test may show normal levels while a magnesium RBC test will give a more accurate result.

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Prostate Specific Antigen (PSA) is produced exclusively by cells of the prostate gland. Used in conjunction with the digital rectal examination, PSA is a useful screening test for benign prostate enlargement, prostatitis and prostate cancer development.

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SHBG (sex hormone binding globulin) binds to testosterone and estradiol. High SHBG may decrease free testosterone and free estradiol.