CPK is creatine phosphokinase, an enzyme in the heart, brain, and skeletal muscle. High CPK can indicate muscle destruction, heart attacks, and central nervous system issues. Long-term exposure to high CPK can load up your kidneys and cause muscle loss and weakness. Sometimes we have no symptoms when CPK is high, but most of the time, we have body aches and soreness. Resistance training can raise CPK, so stop working out for at least five days before the CPK test.

Elevated levels of homocysteine in the blood, known as hyperhomocysteinemia, have been linked to an increased risk of cardiovascular disease, including heart attack and stroke. High homocysteine levels may also be associated with an increased risk of certain other health conditions, such as osteoporosis and pregnancy complications.

Tests included are:

Complete Blood Count with Differential (CBC)
Comprehensive Metabolic Panel (CMP)
Hemoglobin A1c
Cardio IQ Advanced Lipid Panel
Urinalysis, Complete
TSH
Thyroid Free T3
Thyroid Free T4
Reverse T3
TPO Antibodies
Thyroglobulin Antibodies
Homocysteine
Cardio C-Reactive Protein
CPK
Estradiol, Ultra Sensitive
Testosterone Total & Free (LC/MS- No upper limit)
DHEA – S
Prolactin
DHT
IGF-1
Progesterone
Estrone
Total Estrogens
LH + FSH
Anti-Müllerian Hormone (AMH)
Vitamin D (25OHD)
Vitamin B-12
Folate
Ferritin
Iron & TIBC (Total Iron Binding Capacity)

The adrenal gland produces a hormone known as dehydroepiandrosterone (DHEA). It is also made in the brain. DHEA leads to the production of androgens and estrogens (male and female sex hormones). DHEA levels in the body begin to decrease after age 30. Lower DHEA levels are found in people with hormonal disorders, HIV/AIDS, Alzheimer's disease, heart disease, depression, diabetes, inflammation, immune disorders, and osteoporosis. Corticosteroids, birth control taken by mouth, and agents that treat psychiatric disorders may reduce DHEA levels.

Lactate dehydrogenase (LD) is an enzyme that is found in almost all of the body's cells, but only a small amount of it is usually detectable in the blood. LD is released from the cells into the bloodstream when cells are damaged or destroyed. Because of this, the LD test can be used as a general marker of injury to cells. Although there is some overlap, each of the five LD isoenzymes tends to be concentrated in specific body tissues. This panel provides 5 types of isoenzymes to detect if LD is coming from the heart, red blood cells, kidneys, lungs, white blood cells, lymph nodes, muscle, or liver.

Ferritin is a protein that stores iron. Red blood cells need iron to form normally and carry oxygen around your body. Low levels of ferritin lead to iron deficiency anemia, which means you have too few red blood cells. High levels of ferritin can damage your joints, heart, liver, and pancreas.

Lipid Panel: Evaluates the risk for developing atherosclerosis (arterial plaque) and coronary heart disease. This test includes: Total Cholesterol, Triglycerides ,HDL Cholesterol, LDL Cholesterol, Total Cholesterol/HDL Ratio. FASTING REQUIRED.

The LDH (lactate dehydrogenase) blood test measures the level of LDH in your blood. LDH is an enzyme in many body organs and tissues, including the heart, liver, muscles, and red blood cells. The LDH test is often used to help diagnose and monitor various medical conditions, such as anemia, heart attack, and liver disease. It may also be ordered to check for tissue damage or monitor treatment effectiveness for specific conditions. Since lactic dehydrogenase is present in many body tissues, its diagnostic usefulness is limited. Tissue specificity may be enhanced by LDH isoenzyme analysis.

A C-Reactive Protein (CRP) Quantitative test is used to aid in the diagnosis of infections or diseases which cause inflammation. CRP is a protein produced by the liver. Higher than normal concentrations of CRP are often an indicator of infection or inflammation in the body. This test can help determine if an infection is present but not the source of the infection. Conditions that can cause elevated CRP levels include but are not limited to Sepsis, Pelvic Inflammatory Disease, Arthritis, Lupus, Vasculitis, and Inflammatory Bowel Disease.

The erythrocyte sedimentation rate (ESR or sed rate) is the rate at which red blood cells sediment in a period of one hour. It is a common hematology test and is a non-specific measure of inflammation. To perform the test, anticoagulated blood is traditionally placed in an upright tube, known as a Westergren tube, and the rate at which the red blood cells fall is measured and reported in mm at the end of one hour. Elevated levels of ESR are usually found in people who have different types of diseases, such as autoimmune disease, anemia, kidney disease, cancer, and other health complications.

T3 or triiodothyronine is the active form of the thyroid hormone. T3 acts as a metabolic throttle for fueling all of the daily cellular functions. Free T3 is the unbound portion of T3 that is biologically active.

The reverse T3 test has to be done at the same time you do the free T3, and you then measure the ratio between the two by dividing the RT3 into the Free T3. The body produces the benign RT3 naturally to rid itself of excess of T4, but in some cases, such as high or low cortisol, RT3 is produced in excess, which can clog cell receptors from receiving T3. FT3 is usually twenty or more times higher than RT3. NOTE: Reverse T3 is analyzed using a specific technique called liquid chromatography/tandem mass spectrometry (LC/MS-MS). There's a special place in the U.S. where these precise machines needed for LC/MS panels run only on two specific days a week. So, sometimes the clock ticks a bit while we wait for samples to return from their initial collection points. Results may take 7 business days.

This test measures the amount of dihydrotestosterone (DHT) in the blood.  Low DHT has been associated with low libido and high DHT has been linked to acne, hair loss and benign prostatic inflammation in a minority of men.

The thyroid stimulating hormone (TSH) is produced and secreted by the pituitary gland and stimulates the thyroid to produce T3 and T4. When TSH is elevated, low thyroid function may be indicated. If TSH is low it is indicative of high thyroid function. A study found that TSH was suppressed in all subjects after food, so fasting may be suggested although it is not reqired by Quest. Free T4 and Free T4 values did not change significantly after eating.

This panel includes comprehensive testing of the thyroid stimulating hormone (TSH) in addition to free thyroxine (T4) and free triiodothyronine (T3).

The electrolyte panel includes: Carbon dioxide, chloride, potassium, and sodium  

The Cardio IQ® Report provides an in-depth assessment of cardiovascular risks to help physicians recommend the ideal individualized treatment option for patient to minimize cardiovascular disease.

The report is simple, yet comprehensive. It is color-coded to display progressive risk values versus goal using “optimal,” “moderate,” and “high-risk” categories and grouped by functional categories.

Cardio IQ Advanced Lipid Panel The Cardio IQ Advanced Lipid Panel includes:Total Cholesterol, Triglycerides, HDL, LDL and Cholesterol/HDL ratio, LDL Particle Number, LDL Peak Size, LDL Pattern, HDL Large, LDL Small, LDL Medium, Apolipoprotein B, Lipoprotein (a). Fasting is not required prior to collection of a lipid panel. Results for this test take 2 weeks to receive.

A complete blood count CBC with differential test panel measures several components of your blood including:Red blood cells, which carry oxygen, White blood cells, which fight infection, Hemoglobin, the oxygen-carrying protein in red blood cells, Hematocrit, the proportion of red blood cells to the fluid component in your blood (which correlated with blood thickness), and Platelets, which help with blood clotting. This is also called Complete Blood Count (CBC) with Differential and Platelets Blood Test

The A1c test works by measuring the hemoglobin A1c level. Hemoglobin is stored in the red blood cells. When glucose levels are high, the sugar starts to combine with the hemoglobin. It takes the body 8 to 12 weeks to bring hemoglobin A1c levels back to normal. Therefore, if hemoglobin A1c levels are high, that means that there has been a high level of glucose in the blood over the last 2 to 3 months.

Includes liver and kidney function, glucose and electrolytes

The volume measurement, or hct blood test, is the proportion of blood that the red blood cells take up. Hemoglobin, on the other hand, is a density or concentration measurement and is expressed in grams per liter or deciliter. (Hemoglobin is, if you will recall from your high school biology, the iron-based protein that transports oxygen.) RBC is a simple count and is usually expressed as the number of million red blood cells that you have per microliter. Usually, hematocrit is three times the amount of hemoglobin.

Testosterone replacement therapy (TRT) increases hematocrit in most men.  Read more about how to decrease hematocrit.

NOTE: Hematocrit is also part of the CBC panel, so there is no need to order separately if your order already includes CBC.

The Cardio IQ® Insulin Resistance Score (IR), which uses fasting insulin and C-peptide measurements to estimate a person's likelihood of having insulin resistance. It eliminates the need for multiple samples and reduces the chance of errors that can occur with some other tests.

Having a high score (indicating a greater probability of insulin resistance) was linked to an increased risk of developing type 2 diabetes, even after accounting for other risk factors. 

An IR score of <33 suggests that an individual has normal insulin sensitivity.
A score of 33 to 66 suggests that an individual has >4-fold greater odds of having IR compared with an individual with a score <33 .
A score >66 suggests that an individual has >15-fold greater odds of having IR compared to an individual with a score

Fasting Required for 10-12 hours. Water only.

Both chronically low and high levels of glutathione in the body are indicative of potentially debilitating health problems. Glutathione level is a crucial marker for many diseases, both chronic and acute. Given the importance of this protein to human health; discovering your glutathione levels could be one more way to monitor health levels, immune function, and the potential risk of diseases that have been associated with chronically low or high levels of this essential peptide.

Vitamin D is essential for bone health and many metabolic processes. The body derives it from sunlight and food sources. Many people do not get enough sunlight or do not consume enough vitamin D rich foods. This test is important to determine if you need vitamin D supplementation or if your current supplementation is effective.

This Arthritis Panel Includes Sedimentation Rate, Anti-Nuclear Antibody (ANA), Rheumatoid Factor, C-Reactive Protein (CRP), and Serum Uric Acid

Renin, also known as angiotensinogenase, is an enzyme that the kidneys produce to regulate aldosterone production. It’s also essential in the renin–angiotensin aldosterone system (RAAS) which maintains your body’s fluid balance and blood pressure. Aldosterone is the primary of several endogenous members of the class of mineralocorticoids in humans. Aldosterone tends to promote sodium and water retention, and lower plasma postasium concentrations.

Lipoprotein (a) has been called a powerful predictor of premature atherosclerotic vascular disease. As an independent risk factor for premature coronary artery disease, excess Lp(a) concentrations are associated with an increased risk of cardiac death in patients with acute coronary syndromes and with restenosis after angioplasty (PTCA) and coronary bypass procedures. In general, concentrations greater than or equal to 75 nmol/L of Lp(a) in serum are associated with a two- to sixfold increase in risk, depending on the presence of other risk factors.

ApoB Blood Test has been reported to be a powerful indicator of Coronary Artery Disease (CAD). In some patients with CAD, APO B is elevated even in the presence of normal LDL cholesterol. Instead of non-HDL-C levels, ApoB levels may be used to check how well lipid treatment is working. Non-HDL-C is the total cholesterol concentration minus the amount of HDL. A healthcare practitioner may order both an lipoprotein a (associated with high-density lipoprotein (HDL), the "good" cholesterol) and an apo B to determine an apo B/apo A-I ratio. This ratio is sometimes used as an alternative to a total cholesterol/HDL ratio to evaluate risk for developing CVD.

B12 and folic acid blood testing help doctors diagnose central nervous system disorders, anemia, and malabsorption syndromes. B12 and folic acid also play an important role in energy level, muscle strength and memory. Because B12 and folate are derived solely from dietary intake, such as egg yolks, beef, poultry and fish, many people are deficient in these important vitamins.

Alkaline Phosphatase (AP) The isoenzymes test, a diagnostic tool, measures the various forms of alkaline phosphatase (ALP) enzyme that are present in the blood. The body has the enzyme ALP in a variety of tissues, with the liver, bones, kidneys, and intestines having the largest quantities. Isoleucines are the slightly different forms of ALP that various tissues produce.

A single fasting growth hormone (GH) level is of limited value. The secretion of GH is episodic and pulsatile. GH has a half-life of 20 to 25 minutes. Testing for growth hormone deficiency or excess is best done as part of a dynamic test involving specific stimuli (see the online Endocrine Appendices: Growth Hormone Stimulation and Growth Hormone Suppression). Insulin-like growth factor-1 can also be useful in assessing growth hormone status.

Patients with diabetes may get a C-peptide test as a means of distinguishing type 1 diabetes from type 2 diabetes or Maturity onset diabetes of the young (MODY). Measuring C-peptide can help to determine how much of their own natural insulin a person is producing as C-peptide is secreted in equimolar amounts to insulin. C-peptide levels are measured instead of insulin levels because C-peptide can assess a person's own insulin secretion even if they receive insulin injections, and because the liver metabolizes a large and variable amount of insulin secreted into the portal vein but does not metabolize C-peptide, meaning blood C-peptide may be a better measure of portal insulin secretion than insulin itself.

This high sensitivity CRP test is used along other blood markers to assess a patient's potential risk for cardiovascular disease. To illustrate the difference between CRP and hs-CRP, traditional testing measures CRP (quantitative) within the range of 10 to 1,000 mg/L, whereas hs-CRP values range from 0.5 to 10 mg/L. In simpler terms, hs-CRP measures trace amounts of CRP in the blood. Hs-CRP is the analyte of choice for cardiovascular risk assessment

Estrogen is the primary female sex hormone as well as a medication. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. There are three major endogenous estrogens in women and men: estrone, estradiol, and estriol. This test does not specify each of these estrogens.

This test is not the sensitive estradiol test but the regular one. It is not recommended for men (it is adequate for pre-menapausal women).  The results from this test are usually available 2 business days faster than the sensitive estradiol test.

Quest Diagnostics test code 17911 is for a DNA mutation analysis of Methylenetetrahydrofolate Reductase (MTHFR). The test determines if a patient has one, two, or no copies of either of the two mutations in the MTHFR gene, C677T and A1298C.

Changes in the methylenetetrahydrofolate reductase gene can lead to certain health conditions. One of them is hyperhomocysteinemia (high blood levels of homocysteine), which is a risk factor for cerebrovascular disease, cerebral vein thrombosis, coronary artery disease, myocardial infarction, and venous thrombosis. At least 40 mutations in the MTHFR gene have been identified in people with homocystinuria, a disorder in which the body is unable to process certain amino acids properly.

The PTH test is used to help identify hyperparathyroidism, to find the cause of abnormal calcium levels, or to check the status of chronic kidney disease. PTH controls calcium and phosphorus levels in the blood.

The serum iron test measures the amount of iron in your blood. The total iron-binding capacity (TIBC) test looks at how well the iron moves through your body.

A Magnesium RBC test can provide an earlier indicator of magnesium deficiency that a standard magnesium blood test. When levels are low, the body will pull magnesium from the cells to keep blood levels normal. In this case, a magnesium blood test may show normal levels while a magnesium RBC test will give a more accurate result.

The cystatin C test (which also includes estimated creatinine clearance eGFR) can be done along with the creatinine or creatinine clearance test in cases where those tests aren’t appropriate, such as patients taking creatine supplements for bodybuilding. These supplements can increase creatinine and decrease creatinine clearance, which can alarm doctors who fear kidney dysfunction.  This creatinine increase is not clinically relevant, but running a Cystatin C test can give physicians reassurance and allow the patient to keep taking that effective bodybuilding supplement. 

This lab test panel includes Total CK (or CPK) and relative percentage of BB (CK-1), MB (CK-2), and MM (CK-3); the percentage of macro CK, if present. The CK or CPK isoenzyme test is used to diagnose myocardial infarction (MI). Three fractions normally may be found, each an isoenzyme: • MM is found in normal serum. • MB is the myocardial fraction associated with MI and occurs in certain other states. MB can be used in the estimation of infarct size.

D-Dimer is one of the by-products that can be measured after the fibrinolytic system is turned on. Fibrinolytic activation and intravascular thrombosis can be measured by the amount of D-Dimer in the blood. D-Dimer is especially helpful when ruling out venous thromboembolism in people who are at high risk.

This lab test panel includes main blood test makers involved in hair loss in women and men: Complete Blood Count (CBC)- Can detect potential low hemoglobin and infections that can lead to hair loss. Ferritin- Low ferritin, an iron storage protein, has been linked to hair loss and slow down of hair growth. Iron and Total Iron Capacity (TIBC)- Low iron anemia has been linked to hair loss.  Hyperandrogenism: Excessive male hormones (androgens): Total Testosterone (LC/MS), Free Testosterone (Equilibrium Ultrafiltration), DHEA-S, Dihydrotestosterone (DHT)  Hypothyroidism and Hyperthyroidism: Thyroid Stimulation Hormone (TSH), Free Triidothyronine (Free T3)

Comprehensive and All-Inclusive Lab Test Panel for clients of The Wellness By Design Project.  The panel includes:  Testosterone Free with Total, Estrogens Total, Estrone, Estradiol, DHEA-S, Progesterone, Pregnenolone, Dihydrotestosterone (DHT), FSH/LH, Cortisol, Prolactin, TSH, Free T3, Free T4, Reverse T3, Anti TPO, AntiTG, C-reactive protein (high sensitivity), Homocysteine, Apolipoprotein B, Insulin-like Growth Factor 1 (IGF-1), Insulin, Sex Hormone Binding Globulin (SHBG), Vitamin D 25-hydroxy, Complete Metabolic Panel, Gamma Glutamyl Transferase (GGT), Lipid Profile, Complete Blood Count (CBC), Hemoglobin A1C (HbA1C), Magnesium (serum), Phosphorus (serum), LDH, Uric Acid, Iron Serum, Total Iron Binding Capacity (TIBC), Iron Saturation, Ferritin, and Fibrinogen activity.

Women and men living with fibromyalgia do not have characteristic or consistent abnormalities on laboratory testing. However, routine laboratory and imaging studies are important to help rule out diseases with similar manifestations and to assist in diagnosis of certain inflammatory diseases that frequently coexist with fibromyalgia. These are the lab tests commonly checked by physicians treating fibromyalgia patients: CMP, CBC, Urinalysis, TSH, Vitamin D & B-12, Iron/TIBC, Magnesium in RBC, ESR, CPK and Ferritin.

The pre-op (surgery) blood test includes the three test panels (CBC, CMP, and Prothrombin Time Test) most commonly ordered before a person has surgery. Pre-operative testing is usually done during the few days before the surgery. This panel lets your surgeon know what to be aware of in case of complications during surgery.

This diabetes panel includes important tests usually prescribed for anyone living with Type 1 or Type 2 diabetes. It includes A1c, CMP, Urinialysis, Insulin, and Glucose Tolerance Test (GTT).

This panel is the most inclusive of all offered on the site for men who want a wide picture of their health or who are considering starting testosterone replacement therapy.  It provides a baseline overview of your sex hormones, thyroid gland, adrenal function, metabolic function, cholesterol, prostate, and overall health.  Tests included: 

• CBC
• CMP
• Lipid Panel
• Testosterone
• Total (LC/MS) Estradiol, Ultra Sensitive
• DHEA-s
• TSH
• Free T3
• PSA
• LH
• FSH

 A prolactin blood test is used by doctors to evaluate sexual dysfunction or very low testosterone blood levels of unknown causes in both men and women.

The fasting insulin test is a blood test that measures the level of insulin in your blood after you have fasted (not eaten or drunk anything except water) for at least 8 hours. Insulin is a hormone produced by the pancreas that helps regulate blood sugar levels. The fasting insulin test is often used to help diagnose conditions such as insulin resistance, prediabetes, and type 2 diabetes. It may also be ordered to monitor the effectiveness of treatment for these conditions. The test is usually done in the morning, after an overnight fast. The test results will be reported in units of insulin per liter of blood (U/L). It is important to note that the interpretation of a fasting insulin test may vary depending on the individual's medical history and other factors. A healthcare provider should be consulted to interpret the test results correctly.

The Urinalysis test panel screens for a variety of conditions including urinary tract infections ( UTI ), urinary bladder disease, kidney disease and diabetes. Tests included: Color, Appearance, Specific gravity, pH, Protein, Glucose, Occult blood, Ketones, Leukocyte esterase, Nitrite, Bilirubin, Urobilinogen, and Microscopic examination of urine sediment

Uric acid is a product produced by the body after the purines in many foods undergo the digestive process and are broken down inside the body. After this breakdown process, the uric acid travels through the bloodstream into your kidneys and most is actually eliminated through the urinary tract via urination. However, there are instances where you may have an excess of uric acid and are unable to excrete the bulk of this substance through urination. This could lead to gout-related issues.

Vitamin B-12 is an essential vitamin. Low blood levels of B12 can cause: Anemia and pernicious anemia, loss of balance , numbness or tingling in the arms and legs, and weakness